Result of FASTA (omim) for
pF1KE0427
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0427, 178 aa
1>>>pF1KE0427 178 - 178 aa - 178 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9095+/-0.000323; mu= 14.3778+/- 0.020
mean_var=53.9337+/-11.159, 0's: 0 Z-trim(114.6): 24 B-trim: 0 in 0/50
Lambda= 0.174640
statistics sampled from 24598 (24616) to 24598 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.289), width: 16
Scan time: 5.220
The best scores are: opt bits E(85289)
NP_057184 (OMIM: 610833) N-alpha-acetyltransferase ( 178) 1170 302.3 2.6e-82
NP_852668 (OMIM: 610833) N-alpha-acetyltransferase ( 166) 1056 273.6 1.1e-73
NP_852669 (OMIM: 610833) N-alpha-acetyltransferase ( 111) 668 175.8 2.1e-44
NP_003482 (OMIM: 300013,300855,309800) N-alpha-ace ( 235) 255 71.8 8.4e-13
NP_001243049 (OMIM: 300013,300855,309800) N-alpha- ( 229) 217 62.3 6.3e-10
NP_001243048 (OMIM: 300013,300855,309800) N-alpha- ( 220) 192 56.0 4.8e-08
NP_001295374 (OMIM: 610834) N-alpha-acetyltransfer ( 168) 145 44.1 0.00014
NP_079422 (OMIM: 610834) N-alpha-acetyltransferase ( 169) 145 44.1 0.00014
>>NP_057184 (OMIM: 610833) N-alpha-acetyltransferase 20 (178 aa)
initn: 1170 init1: 1170 opt: 1170 Z-score: 1598.6 bits: 302.3 E(85289): 2.6e-82
Smith-Waterman score: 1170; 98.9% identity (98.9% similar) in 178 aa overlap (1-178:1-178)
10 20 30 40 50 60
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGELMGYIMGK
::: :::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_057 MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAV
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 NMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
130 140 150 160 170
>>NP_852668 (OMIM: 610833) N-alpha-acetyltransferase 20 (166 aa)
initn: 1056 init1: 1056 opt: 1056 Z-score: 1443.9 bits: 273.6 E(85289): 1.1e-73
Smith-Waterman score: 1056; 99.4% identity (99.4% similar) in 160 aa overlap (19-178:7-166)
10 20 30 40 50 60
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGELMGYIMGK
:::::::::::::::::::::::::::: :::::::::::::
NP_852 MLSQSCNLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGK
10 20 30 40
70 80 90 100 110 120
pF1KE0 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAV
50 60 70 80 90 100
130 140 150 160 170
pF1KE0 NMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
110 120 130 140 150 160
>>NP_852669 (OMIM: 610833) N-alpha-acetyltransferase 20 (111 aa)
initn: 668 init1: 668 opt: 668 Z-score: 918.2 bits: 175.8 E(85289): 2.1e-44
Smith-Waterman score: 668; 98.0% identity (98.0% similar) in 102 aa overlap (1-102:1-102)
10 20 30 40 50 60
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGELMGYIMGK
::: :::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_852 MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAV
::::::::::::::::::::::::::::::::::::::::::
NP_852 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERYEESTFQGY
70 80 90 100 110
130 140 150 160 170
pF1KE0 NMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
>>NP_003482 (OMIM: 300013,300855,309800) N-alpha-acetylt (235 aa)
initn: 227 init1: 112 opt: 255 Z-score: 350.8 bits: 71.8 E(85289): 8.4e-13
Smith-Waterman score: 255; 33.1% identity (66.9% similar) in 151 aa overlap (10-158:9-153)
10 20 30 40 50 60
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGELMGYIMGK
.::. ... :: : :.: . .:. . ::. .: .:...::...:
NP_003 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAK
10 20 30 40 50
70 80 90 100 110
pF1KE0 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEE-ISERKGGFFVDLFVRVSNQVA
: . . :::.:.:.: :::::: :::. . . : .. .:.: :: ::..:
NP_003 MEED-PDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VNMYKQ-LGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
...:.. :.... .. .::. .:: ::: :.. :..
NP_003 LHLYSNTLNFQISEVEPKYYA--DGE---DAYAMKRDLTQMADELRRHLELKEKGRHVVL
120 130 140 150 160 170
NP_003 GAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDS
180 190 200 210 220 230
>>NP_001243049 (OMIM: 300013,300855,309800) N-alpha-acet (229 aa)
initn: 224 init1: 99 opt: 217 Z-score: 299.3 bits: 62.3 E(85289): 6.3e-10
Smith-Waterman score: 217; 31.8% identity (63.6% similar) in 151 aa overlap (10-158:9-147)
10 20 30 40 50 60
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGELMGYIMGK
.::. ... :: : :.: . .:. . ::. .: .:...: .
NP_001 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGE---E
10 20 30 40 50
70 80 90 100 110
pF1KE0 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEE-ISERKGGFFVDLFVRVSNQVA
.: :::.:.:.: :::::: :::. . . : .. .:.: :: ::..:
NP_001 DPDDVP----HGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VNMYKQ-LGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
...:.. :.... .. .::. .:: ::: :.. :..
NP_001 LHLYSNTLNFQISEVEPKYYA--DGE---DAYAMKRDLTQMADELRRHLELKEKGRHVVL
120 130 140 150 160
NP_001 GAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDS
170 180 190 200 210 220
>>NP_001243048 (OMIM: 300013,300855,309800) N-alpha-acet (220 aa)
initn: 227 init1: 112 opt: 192 Z-score: 265.5 bits: 56.0 E(85289): 4.8e-08
Smith-Waterman score: 192; 34.3% identity (63.8% similar) in 105 aa overlap (10-113:9-112)
10 20 30 40 50 60
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGELMGYIMGK
.::. ... :: : :.: . .:. . ::. .: .:...::...:
NP_001 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAK
10 20 30 40 50
70 80 90 100 110
pF1KE0 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEE-ISERKGGFFVDLFVRVSNQVA
: . . :::.:.:.: :::::: :::. . . : .. .:.: ::
NP_001 MEED-PDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKRISEV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VNMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
NP_001 EPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGNSPPSSGEA
120 130 140 150 160 170
>>NP_001295374 (OMIM: 610834) N-alpha-acetyltransferase (168 aa)
initn: 108 init1: 81 opt: 145 Z-score: 203.3 bits: 44.1 E(85289): 0.00014
Smith-Waterman score: 147; 27.2% identity (57.1% similar) in 147 aa overlap (19-156:14-153)
10 20 30 40 50
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGEL--MGYIM
:. : . . : ..: . : : ::: ..:.
NP_001 MKGRIELGDVTPHNIKQLKRLNQVIFPVSY----NDKFYKDVLEVGELAKLAYFN
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 GKAEGSVAREEWHG------HVTALSVAPEFRRLGLAAKLMELLEEISERKGGF-FVDLF
: :.: . :. .. .:. .::::...:... . .: :. : : . :
NP_001 DIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHP
:..::. :...:...:. . .: .:: . :: ::. ..: :
NP_001 VQISNESAIDFYRKFGFEIIETKKNYY--KRIEP-ADAHVLQKNLKVPSGQNADVQKTDN
120 130 140 150 160
pF1KE0 VRPEDIE
>>NP_079422 (OMIM: 610834) N-alpha-acetyltransferase 50 (169 aa)
initn: 108 init1: 81 opt: 145 Z-score: 203.3 bits: 44.1 E(85289): 0.00014
Smith-Waterman score: 147; 27.2% identity (57.1% similar) in 147 aa overlap (19-156:15-154)
10 20 30 40 50
pF1KE0 MTTPRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAVAPGGEL--MGYIM
:. : . . : ..: . : : ::: ..:.
NP_079 MKGSRIELGDVTPHNIKQLKRLNQVIFPVSY----NDKFYKDVLEVGELAKLAYFN
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 GKAEGSVAREEWHG------HVTALSVAPEFRRLGLAAKLMELLEEISERKGGF-FVDLF
: :.: . :. .. .:. .::::...:... . .: :. : : . :
NP_079 DIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHP
:..::. :...:...:. . .: .:: . :: ::. ..: :
NP_079 VQISNESAIDFYRKFGFEIIETKKNYY--KRIEP-ADAHVLQKNLKVPSGQNADVQKTDN
120 130 140 150 160
pF1KE0 VRPEDIE
178 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:23:48 2016 done: Thu Nov 3 10:23:48 2016
Total Scan time: 5.220 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]