Result of FASTA (omim) for
pF1KE0395
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0395, 1188 aa
1>>>pF1KE0395 1188 - 1188 aa - 1188 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7060+/-0.000435; mu= 2.0175+/- 0.027
mean_var=222.3409+/-45.051, 0's: 0 Z-trim(118.3): 63 B-trim: 96 in 2/57
Lambda= 0.086013
statistics sampled from 31029 (31092) to 31029 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.365), width: 16
Scan time: 16.170
The best scores are: opt bits E(85289)
NP_115575 (OMIM: 608538) AT-rich interactive domai (1188) 8000 1006.7 0
XP_011538564 (OMIM: 608538) PREDICTED: AT-rich int (1111) 6342 800.9 0
NP_001231567 (OMIM: 608538) AT-rich interactive do ( 945) 6332 799.6 0
XP_016872254 (OMIM: 608538) PREDICTED: AT-rich int ( 696) 4667 592.9 2.3e-168
NP_997646 (OMIM: 611583) AT-rich interactive domai ( 594) 649 94.3 2.5e-18
XP_011508801 (OMIM: 611583) PREDICTED: AT-rich int ( 604) 649 94.3 2.5e-18
NP_001306021 (OMIM: 611583) AT-rich interactive do ( 526) 566 84.0 2.8e-15
XP_016858673 (OMIM: 611583) PREDICTED: AT-rich int ( 542) 379 60.8 2.8e-08
XP_016858674 (OMIM: 611583) PREDICTED: AT-rich int ( 542) 379 60.8 2.8e-08
NP_001306016 (OMIM: 611583) AT-rich interactive do ( 647) 379 60.8 3.2e-08
NP_001306014 (OMIM: 611583) AT-rich interactive do ( 648) 379 60.8 3.2e-08
XP_016858672 (OMIM: 611583) PREDICTED: AT-rich int ( 657) 379 60.8 3.3e-08
NP_057458 (OMIM: 609696) AT-rich interactive domai (1312) 337 55.8 2.1e-06
NP_001193723 (OMIM: 609696) AT-rich interactive do (1312) 337 55.8 2.1e-06
XP_011542514 (OMIM: 609696) PREDICTED: AT-rich int (1312) 337 55.8 2.1e-06
XP_016856957 (OMIM: 609696) PREDICTED: AT-rich int (1314) 337 55.8 2.1e-06
XP_016856961 (OMIM: 609696) PREDICTED: AT-rich int (1019) 331 55.0 2.9e-06
XP_016856960 (OMIM: 609696) PREDICTED: AT-rich int (1057) 307 52.0 2.4e-05
NP_112739 (OMIM: 609696) AT-rich interactive domai (1226) 307 52.0 2.7e-05
XP_016856959 (OMIM: 609696) PREDICTED: AT-rich int (1228) 307 52.0 2.7e-05
XP_006711844 (OMIM: 609696) PREDICTED: AT-rich int (1276) 307 52.1 2.8e-05
XP_016856958 (OMIM: 609696) PREDICTED: AT-rich int (1278) 307 52.1 2.8e-05
XP_016877053 (OMIM: 180201) PREDICTED: AT-rich int (1137) 266 46.9 0.00086
NP_075377 (OMIM: 180201) AT-rich interactive domai (1188) 266 46.9 0.00089
NP_075376 (OMIM: 180201) AT-rich interactive domai (1203) 266 47.0 0.0009
XP_005268022 (OMIM: 180201) PREDICTED: AT-rich int (1208) 266 47.0 0.0009
XP_016877052 (OMIM: 180201) PREDICTED: AT-rich int (1215) 266 47.0 0.0009
NP_002883 (OMIM: 180201) AT-rich interactive domai (1257) 266 47.0 0.00093
XP_016877051 (OMIM: 180201) PREDICTED: AT-rich int (1264) 266 47.0 0.00093
XP_005268021 (OMIM: 180201) PREDICTED: AT-rich int (1277) 266 47.0 0.00094
XP_016877050 (OMIM: 180201) PREDICTED: AT-rich int (1284) 266 47.0 0.00095
XP_016877049 (OMIM: 180201) PREDICTED: AT-rich int (1284) 266 47.0 0.00095
>>NP_115575 (OMIM: 608538) AT-rich interactive domain-co (1188 aa)
initn: 8000 init1: 8000 opt: 8000 Z-score: 5375.6 bits: 1006.7 E(85289): 0
Smith-Waterman score: 8000; 100.0% identity (100.0% similar) in 1188 aa overlap (1-1188:1-1188)
10 20 30 40 50 60
pF1KE0 MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVRCTPKDPICIAELQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVRCTPKDPICIAELQLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWVHSDFSKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 WEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWVHSDFSKW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 RCGFHAGPVKTEALGRNGQKEALLKYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RCGFHAGPVKTEALGRNGQKEALLKYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 YPQYCRYRSMLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YPQYCRYRSMLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CDEFAPNLKGRPRKKKPCPQRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKPKNNHNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 CDEFAPNLKGRPRKKKPCPQRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKPKNNHNC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KKVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KPRKQENSSQENENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKEQETLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KPRKQENSSQENENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKEQETLIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 QKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQGSNSEKVAEEAGEKGPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQGSNSEKVAEEAGEKGPTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 PLPSAPLAPEKDSALVPGASKQPLTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PLPSAPLAPEKDSALVPGASKQPLTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 TQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMFKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMFKDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 DLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLSR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 SDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHSHMPSFLADFYSSPHLHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHSHMPSFLADFYSSPHLHSL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 YRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHRHQEKLHVNYLTSLHLQDKKSAAAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHRHQEKLHVNYLTSLHLQDKKSAAAEAP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQESKGISQFQVLGSQSRDCHPKACRVSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQESKGISQFQVLGSQSRDCHPKACRVSPM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 TMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVHPILHRKMSPQNIGAARPIKRSLEDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVHPILHRKMSPQNIGAARPIKRSLEDLD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 LVIAGKKARAVSPLDPSKEVSGKEKASEQESEGSKAAHGGHSGGGSEGHKLPLSSPIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LVIAGKKARAVSPLDPSKEVSGKEKASEQESEGSKAAHGGHSGGGSEGHKLPLSSPIFPG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 LYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KE0 YRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL
1150 1160 1170 1180
>>XP_011538564 (OMIM: 608538) PREDICTED: AT-rich interac (1111 aa)
initn: 6335 init1: 6335 opt: 6342 Z-score: 4264.1 bits: 800.9 E(85289): 0
Smith-Waterman score: 7319; 93.5% identity (93.5% similar) in 1188 aa overlap (1-1188:1-1111)
10 20 30 40 50 60
pF1KE0 MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVRCTPKDPICIAELQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVRCTPKDPICIAELQLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWVHSDFSKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWVHSDFSKW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 RCGFHAGPVKTEALGRNGQKEALLKYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCGFHAGPVKTEALGRNGQKEALLKYRQSTLNSGLNFKDVLKEKADL-------------
130 140 150 160
190 200 210 220 230 240
pF1KE0 YPQYCRYRSMLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENESI
XP_011 ------------------------------------------------------------
250 260 270 280 290 300
pF1KE0 CDEFAPNLKGRPRKKKPCPQRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKPKNNHNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----APNLKGRPRKKKPCPQRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKPKNNHNC
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE0 KKVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQ
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE0 KLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPI
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE0 KPRKQENSSQENENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKEQETLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPRKQENSSQENENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKEQETLIS
350 360 370 380 390 400
490 500 510 520 530 540
pF1KE0 QKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQGSNSEKVAEEAGEKGPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQGSNSEKVAEEAGEKGPTP
410 420 430 440 450 460
550 560 570 580 590 600
pF1KE0 PLPSAPLAPEKDSALVPGASKQPLTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPSAPLAPEKDSALVPGASKQPLTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPT
470 480 490 500 510 520
610 620 630 640 650 660
pF1KE0 TQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMFKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMFKDK
530 540 550 560 570 580
670 680 690 700 710 720
pF1KE0 DLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKK
590 600 610 620 630 640
730 740 750 760 770 780
pF1KE0 KLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLSR
650 660 670 680 690 700
790 800 810 820 830 840
pF1KE0 SDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHSHMPSFLADFYSSPHLHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHSHMPSFLADFYSSPHLHSL
710 720 730 740 750 760
850 860 870 880 890 900
pF1KE0 YRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHRHQEKLHVNYLTSLHLQDKKSAAAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHRHQEKLHVNYLTSLHLQDKKSAAAEAP
770 780 790 800 810 820
910 920 930 940 950 960
pF1KE0 TDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQESKGISQFQVLGSQSRDCHPKACRVSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQESKGISQFQVLGSQSRDCHPKACRVSPM
830 840 850 860 870 880
970 980 990 1000 1010 1020
pF1KE0 TMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVHPILHRKMSPQNIGAARPIKRSLEDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVHPILHRKMSPQNIGAARPIKRSLEDLD
890 900 910 920 930 940
1030 1040 1050 1060 1070 1080
pF1KE0 LVIAGKKARAVSPLDPSKEVSGKEKASEQESEGSKAAHGGHSGGGSEGHKLPLSSPIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVIAGKKARAVSPLDPSKEVSGKEKASEQESEGSKAAHGGHSGGGSEGHKLPLSSPIFPG
950 960 970 980 990 1000
1090 1100 1110 1120 1130 1140
pF1KE0 LYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQL
1010 1020 1030 1040 1050 1060
1150 1160 1170 1180
pF1KE0 YRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL
1070 1080 1090 1100 1110
>>NP_001231567 (OMIM: 608538) AT-rich interactive domain (945 aa)
initn: 6332 init1: 6332 opt: 6332 Z-score: 4258.4 bits: 799.6 E(85289): 0
Smith-Waterman score: 6332; 100.0% identity (100.0% similar) in 944 aa overlap (245-1188:2-945)
220 230 240 250 260 270
pF1KE0 VVSRNPQILYCRDTFDHPTLIENESICDEFAPNLKGRPRKKKPCPQRRDSFSGVKDSNNN
::::::::::::::::::::::::::::::
NP_001 MAPNLKGRPRKKKPCPQRRDSFSGVKDSNNN
10 20 30
280 290 300 310 320 330
pF1KE0 SDGKAVAKVKCEARSALTKPKNNHNCKKVSNEEKPKVAIGEECRADEQAFLVALYKYMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDGKAVAKVKCEARSALTKPKNNHNCKKVSNEEKPKVAIGEECRADEQAFLVALYKYMKE
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE0 RKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCT
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE0 RRHYERLILPYERFIKGEEDKPLPPIKPRKQENSSQENENKTKVSGTKRIKHEIPKSKKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRHYERLILPYERFIKGEEDKPLPPIKPRKQENSSQENENKTKVSGTKRIKHEIPKSKKE
160 170 180 190 200 210
460 470 480 490 500 510
pF1KE0 KENAPKPQDAAEVSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KENAPKPQDAAEVSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDP
220 230 240 250 260 270
520 530 540 550 560 570
pF1KE0 EKDNETDQGSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQPLTSPSALVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDNETDQGSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQPLTSPSALVDSK
280 290 300 310 320 330
580 590 600 610 620 630
pF1KE0 QESKLCCFTESPESEPQEASFPSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QESKLCCFTESPESEPQEASFPSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLG
340 350 360 370 380 390
640 650 660 670 680 690
pF1KE0 SDDIHNALKQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDDIHNALKQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKK
400 410 420 430 440 450
700 710 720 730 740 750
pF1KE0 LLSQVSGASLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSQVSGASLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQH
460 470 480 490 500 510
760 770 780 790 800 810
pF1KE0 VQSFRSKPSEERKTINDIFKHEKLSRSDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQSFRSKPSEERKTINDIFKHEKLSRSDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLL
520 530 540 550 560 570
820 830 840 850 860 870
pF1KE0 EKRALPHSHMPSFLADFYSSPHLHSLYRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRALPHSHMPSFLADFYSSPHLHSLYRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHR
580 590 600 610 620 630
880 890 900 910 920 930
pF1KE0 HQEKLHVNYLTSLHLQDKKSAAAEAPTDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQEKLHVNYLTSLHLQDKKSAAAEAPTDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQES
640 650 660 670 680 690
940 950 960 970 980 990
pF1KE0 KGISQFQVLGSQSRDCHPKACRVSPMTMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGISQFQVLGSQSRDCHPKACRVSPMTMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVH
700 710 720 730 740 750
1000 1010 1020 1030 1040 1050
pF1KE0 PILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPSKEVSGKEKASEQESEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPSKEVSGKEKASEQESEGS
760 770 780 790 800 810
1060 1070 1080 1090 1100 1110
pF1KE0 KAAHGGHSGGGSEGHKLPLSSPIFPGLYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAHGGHSGGGSEGHKLPLSSPIFPGLYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSP
820 830 840 850 860 870
1120 1130 1140 1150 1160 1170
pF1KE0 LMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAF
880 890 900 910 920 930
1180
pF1KE0 PSSQLSSVHPSTKL
::::::::::::::
NP_001 PSSQLSSVHPSTKL
940
>>XP_016872254 (OMIM: 608538) PREDICTED: AT-rich interac (696 aa)
initn: 4667 init1: 4667 opt: 4667 Z-score: 3143.8 bits: 592.9 E(85289): 2.3e-168
Smith-Waterman score: 4667; 100.0% identity (100.0% similar) in 696 aa overlap (493-1188:1-696)
470 480 490 500 510 520
pF1KE0 DAAEVSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQ
::::::::::::::::::::::::::::::
XP_016 MKKKIEGYQEFSAKPLASRVDPEKDNETDQ
10 20 30
530 540 550 560 570 580
pF1KE0 GSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQPLTSPSALVDSKQESKLCCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQPLTSPSALVDSKQESKLCCF
40 50 60 70 80 90
590 600 610 620 630 640
pF1KE0 TESPESEPQEASFPSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESPESEPQEASFPSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNAL
100 110 120 130 140 150
650 660 670 680 690 700
pF1KE0 KQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGA
160 170 180 190 200 210
710 720 730 740 750 760
pF1KE0 SLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKP
220 230 240 250 260 270
770 780 790 800 810 820
pF1KE0 SEERKTINDIFKHEKLSRSDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEERKTINDIFKHEKLSRSDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHS
280 290 300 310 320 330
830 840 850 860 870 880
pF1KE0 HMPSFLADFYSSPHLHSLYRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHRHQEKLHVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMPSFLADFYSSPHLHSLYRHTEHHLHNEQTSKYPSRDMYRESENSSFPSHRHQEKLHVN
340 350 360 370 380 390
890 900 910 920 930 940
pF1KE0 YLTSLHLQDKKSAAAEAPTDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQESKGISQFQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLTSLHLQDKKSAAAEAPTDDQPTDLSLPKNPHKPTGKVLGLAHSTTGPQESKGISQFQV
400 410 420 430 440 450
950 960 970 980 990 1000
pF1KE0 LGSQSRDCHPKACRVSPMTMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVHPILHRKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSQSRDCHPKACRVSPMTMSGPKKYPESLSRSGKPHHVRLENFRKMEGMVHPILHRKMS
460 470 480 490 500 510
1010 1020 1030 1040 1050 1060
pF1KE0 PQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPSKEVSGKEKASEQESEGSKAAHGGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPSKEVSGKEKASEQESEGSKAAHGGHS
520 530 540 550 560 570
1070 1080 1090 1100 1110 1120
pF1KE0 GGGSEGHKLPLSSPIFPGLYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGSEGHKLPLSSPIFPGLYSGSLCNSGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFH
580 590 600 610 620 630
1130 1140 1150 1160 1170 1180
pF1KE0 SLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSV
640 650 660 670 680 690
pF1KE0 HPSTKL
::::::
XP_016 HPSTKL
>>NP_997646 (OMIM: 611583) AT-rich interactive domain-co (594 aa)
initn: 798 init1: 604 opt: 649 Z-score: 450.2 bits: 94.3 E(85289): 2.5e-18
Smith-Waterman score: 666; 33.5% identity (56.0% similar) in 457 aa overlap (290-722:22-447)
260 270 280 290 300 310
pF1KE0 QRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKP--KNNHNCKKVSNEEKPKVAIGE--
: :: :.: . .: :..:. : ::
NP_997 MAAPVKGNRKQSTEGDALDPPASPKPAGKQNGIQNPISLEDSPE-AGGERE
10 20 30 40 50
320 330 340 350 360 370
pF1KE0 --ECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQ
. : .::::::.:::.::::.:::::.:.::::::::: ...:..:::.:: .:.::
NP_997 EEQEREEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRL
60 70 80 90 100 110
380 390 400 410 420 430
pF1KE0 WKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENSSQEN-
::..::::::.:::::::::::::::::.::: : .:::.::::: ::::: . ..::
NP_997 WKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENR
120 130 140 150 160 170
440 450 460 470 480
pF1KE0 ------ENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKEQETLISQKSIPE
: :.. .:. . .: . : : : . : .. ::. : : .:.
NP_997 GDDGATERPKKAKEERRMDQMMPGKTKADAADPAPLPSQE-PPRNSTEQQGLASGSSVSF
180 190 200 210 220
490 500 510 520 530 540
pF1KE0 PLPAADMKKKIEGYQEFSAKPLASRVDP-EKDNETDQGSNSE--KVAEEAGEKGPTP---
.. . . . : : . ..: : . : :. : . ::. ..: :
NP_997 VGASGCPEAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQAS
230 240 250 260 270 280
550 560 570 580 590
pF1KE0 PLPSAPLAPEKDSALVPGAS-----KQPLTSPSALVDSKQESKLCCFTESPESEPQEASF
: : .:.. ..:. .. .. : .:.. . . .. : : . .. :
NP_997 PAVHLPESPQSPKGLTENSRHRLTPQEGLQAPGGSLREEAQAGPC-----PAAPIFKGCF
290 300 310 320 330 340
600 610 620 630 640 650
pF1KE0 PSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFD
. :: ..:. : . . : . :: .. : :. .
NP_997 YTHPTEVLKPVSQHPR--DFFSRLKDGVL--------LGPPGKEG--------LSVKEPQ
350 360 370 380
660 670 680 690 700 710
pF1KE0 MFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPP
. : . : ..: . .:: . . .::.:: : .: ..: : :
NP_997 LVWGGDANRPSAFHKGGSRKGILYPKPKACWVSPMAKVPAES----PTLPPTFP--SSPG
390 400 410 420 430 440
720 730 740 750 760 770
pF1KE0 LISKKKLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKH
: ::..:
NP_997 LGSKRSLEEEGAAHSGKRLRAVSPFLKEADAKKCGAKPAGSGLVSCLLGPALGPVPPEAY
450 460 470 480 490 500
>>XP_011508801 (OMIM: 611583) PREDICTED: AT-rich interac (604 aa)
initn: 798 init1: 604 opt: 649 Z-score: 450.1 bits: 94.3 E(85289): 2.5e-18
Smith-Waterman score: 666; 33.5% identity (56.0% similar) in 457 aa overlap (290-722:32-457)
260 270 280 290 300 310
pF1KE0 QRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKP--KNNHNCKKVSNEEKPKVAIGE--
: :: :.: . .: :..:. : ::
XP_011 VLKRKMQYCKAAPVKGNRKQSTEGDALDPPASPKPAGKQNGIQNPISLEDSPE-AGGERE
10 20 30 40 50 60
320 330 340 350 360 370
pF1KE0 --ECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQ
. : .::::::.:::.::::.:::::.:.::::::::: ...:..:::.:: .:.::
XP_011 EEQEREEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRL
70 80 90 100 110 120
380 390 400 410 420 430
pF1KE0 WKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENSSQEN-
::..::::::.:::::::::::::::::.::: : .:::.::::: ::::: . ..::
XP_011 WKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENR
130 140 150 160 170 180
440 450 460 470 480
pF1KE0 ------ENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKEQETLISQKSIPE
: :.. .:. . .: . : : : . : .. ::. : : .:.
XP_011 GDDGATERPKKAKEERRMDQMMPGKTKADAADPAPLPSQE-PPRNSTEQQGLASGSSVSF
190 200 210 220 230
490 500 510 520 530 540
pF1KE0 PLPAADMKKKIEGYQEFSAKPLASRVDP-EKDNETDQGSNSE--KVAEEAGEKGPTP---
.. . . . : : . ..: : . : :. : . ::. ..: :
XP_011 VGASGCPEAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQAS
240 250 260 270 280 290
550 560 570 580 590
pF1KE0 PLPSAPLAPEKDSALVPGAS-----KQPLTSPSALVDSKQESKLCCFTESPESEPQEASF
: : .:.. ..:. .. .. : .:.. . . .. : : . .. :
XP_011 PAVHLPESPQSPKGLTENSRHRLTPQEGLQAPGGSLREEAQAGPC-----PAAPIFKGCF
300 310 320 330 340 350
600 610 620 630 640 650
pF1KE0 PSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFD
. :: ..:. : . . : . :: .. : :. .
XP_011 YTHPTEVLKPVSQHPR--DFFSRLKDGVL--------LGPPGKEG--------LSVKEPQ
360 370 380 390
660 670 680 690 700 710
pF1KE0 MFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPP
. : . : ..: . .:: . . .::.:: : .: ..: : :
XP_011 LVWGGDANRPSAFHKGGSRKGILYPKPKACWVSPMAKVPAES----PTLPPTFP--SSPG
400 410 420 430 440 450
720 730 740 750 760 770
pF1KE0 LISKKKLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKH
: ::..:
XP_011 LGSKRSLEEEGAAHSGKRLRAVSPFLKEADAKKCGAKPAGSGLVSCLLGPALGPVPPEAY
460 470 480 490 500 510
>>NP_001306021 (OMIM: 611583) AT-rich interactive domain (526 aa)
initn: 725 init1: 531 opt: 566 Z-score: 395.3 bits: 84.0 E(85289): 2.8e-15
Smith-Waterman score: 583; 32.3% identity (55.0% similar) in 409 aa overlap (332-722:1-379)
310 320 330 340 350 360
pF1KE0 KVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQK
::::.:::::.:.::::::::: ...:..:
NP_001 MKERHTPIERVPHLGFKQINLWKIYKAVEK
10 20 30
370 380 390 400 410 420
pF1KE0 LGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIK
::.:: .:.:: ::..::::::.:::::::::::::::::.::: : .:::.::::: :
NP_001 LGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPTSK
40 50 60 70 80 90
430 440 450 460 470
pF1KE0 PRKQENSSQEN-------ENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKE
:::: . ..:: : :.. .:. . .: . : : : . : .. :
NP_001 PRKQYKMAKENRGDDGATERPKKAKEERRMDQMMPGKTKADAADPAPLPSQE-PPRNSTE
100 110 120 130 140
480 490 500 510 520 530
pF1KE0 QETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDP-EKDNETDQGSNSE--KVAE
:. : : .:. .. . . . : : . ..: : . : :. : . :
NP_001 QQGLASGSSVSFVGASGCPEAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKVEALQCQE
150 160 170 180 190 200
540 550 560 570 580
pF1KE0 EAGEKGPTP---PLPSAPLAPEKDSALVPGAS-----KQPLTSPSALVDSKQESKLCCFT
:. ..: : : : .:.. ..:. .. .. : .:.. . . .. :
NP_001 EGCRHGAEPQASPAVHLPESPQSPKGLTENSRHRLTPQEGLQAPGGSLREEAQAGPC---
210 220 230 240 250 260
590 600 610 620 630 640
pF1KE0 ESPESEPQEASFPSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALK
: . .. : . :: ..:. : . . : . :: ..
NP_001 --PAAPIFKGCFYTHPTEVLKPVSQHPR--DFFSRLKDGVL--------LGPPGKEG---
270 280 290 300 310
650 660 670 680 690 700
pF1KE0 QTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGAS
: :. .. : . : ..: . .:: . . .::.:: : .
NP_001 -----LSVKEPQLVWGGDANRPSAFHKGGSRKGILYPKPKACWVSPMAKVPAESP----T
320 330 340 350 360
710 720 730 740 750 760
pF1KE0 LSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPS
: ..: : : : ::..:
NP_001 LPPTFP--SSPGLGSKRSLEEEGAAHSGKRLRAVSPFLKEADAKKCGAKPAGSGLVSCLL
370 380 390 400 410 420
>>XP_016858673 (OMIM: 611583) PREDICTED: AT-rich interac (542 aa)
initn: 538 init1: 344 opt: 379 Z-score: 269.7 bits: 60.8 E(85289): 2.8e-08
Smith-Waterman score: 396; 28.1% identity (51.9% similar) in 374 aa overlap (368-722:53-395)
340 350 360 370 380 390
pF1KE0 PIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRH
.:.:: ::..::::::.:::::::::::::
XP_016 LRVPARAAGAARTPPPGGARRPRPHEVPLQVTGRRLWKNVYDELGGSPGSTSAATCTRRH
30 40 50 60 70 80
400 410 420 430 440 450
pF1KE0 YERLILPYERFIKGEEDKPLPPIKPRKQENSSQEN-------ENKTKVSGTKRIKHEIPK
::::.::: : .:::.::::: ::::: . ..:: : :.. .:. . .:
XP_016 YERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENRGDDGATERPKKAKEERRMDQMMPG
90 100 110 120 130 140
460 470 480 490 500 510
pF1KE0 SKKEKENAPKPQDAAEVSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLAS
. : : : . : .. ::. : : .:. .. . . . : : .
XP_016 KTKADAADPAPLPSQE-PPRNSTEQQGLASGSSVSFVGASGCPEAYKRLLSSFYCKGTHG
150 160 170 180 190 200
520 530 540 550 560
pF1KE0 RVDP-EKDNETDQGSNSE--KVAEEAGEKGPTP---PLPSAPLAPEKDSALVPGAS----
..: : . : :. : . ::. ..: : : : .:.. ..:. ..
XP_016 IMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQASPAVHLPESPQSPKGLTENSRHRLT
210 220 230 240 250 260
570 580 590 600 610
pF1KE0 -KQPLTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPT-TQPPLANQNETEDDKLPA
.. : .:.. . . .. : : . .. : . :: . :.... . : .
XP_016 PQEGLQAPGGSLREEAQAGPC-----PAAPIFKGCFYTHPTEVLKPVSQHPR---DFFSR
270 280 290 300 310
620 630 640 650 660 670
pF1KE0 MADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLL
. : . :: .. . :. . : . : ..: . .:
XP_016 LKDGVL--------LGPPGKEGLSVKEPQ--------LVWGGDANRPSAFHKGGSRKGIL
320 330 340 350
680 690 700 710 720 730
pF1KE0 YSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHG
: . . .::.:: . . .: ..: : : : ::..:
XP_016 YPKPKACWVSPMAK----VPAESPTLPPTFP--SSPGLGSKRSLEEEGAAHSGKRLRAVS
360 370 380 390 400 410
740 750 760 770 780 790
pF1KE0 QSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLSRSDPHRCSFSKHHLNPLAD
XP_016 PFLKEADAKKCGAKPAGSGLVSCLLGPALGPVPPEAYRGTMLHCPLNFTGTPGPLKGQAA
420 430 440 450 460 470
>>XP_016858674 (OMIM: 611583) PREDICTED: AT-rich interac (542 aa)
initn: 538 init1: 344 opt: 379 Z-score: 269.7 bits: 60.8 E(85289): 2.8e-08
Smith-Waterman score: 396; 28.1% identity (51.9% similar) in 374 aa overlap (368-722:53-395)
340 350 360 370 380 390
pF1KE0 PIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRH
.:.:: ::..::::::.:::::::::::::
XP_016 LRVPARAAGAARTPPPGGARRPRPHEVPLQVTGRRLWKNVYDELGGSPGSTSAATCTRRH
30 40 50 60 70 80
400 410 420 430 440 450
pF1KE0 YERLILPYERFIKGEEDKPLPPIKPRKQENSSQEN-------ENKTKVSGTKRIKHEIPK
::::.::: : .:::.::::: ::::: . ..:: : :.. .:. . .:
XP_016 YERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENRGDDGATERPKKAKEERRMDQMMPG
90 100 110 120 130 140
460 470 480 490 500 510
pF1KE0 SKKEKENAPKPQDAAEVSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLAS
. : : : . : .. ::. : : .:. .. . . . : : .
XP_016 KTKADAADPAPLPSQE-PPRNSTEQQGLASGSSVSFVGASGCPEAYKRLLSSFYCKGTHG
150 160 170 180 190 200
520 530 540 550 560
pF1KE0 RVDP-EKDNETDQGSNSE--KVAEEAGEKGPTP---PLPSAPLAPEKDSALVPGAS----
..: : . : :. : . ::. ..: : : : .:.. ..:. ..
XP_016 IMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQASPAVHLPESPQSPKGLTENSRHRLT
210 220 230 240 250 260
570 580 590 600 610
pF1KE0 -KQPLTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPT-TQPPLANQNETEDDKLPA
.. : .:.. . . .. : : . .. : . :: . :.... . : .
XP_016 PQEGLQAPGGSLREEAQAGPC-----PAAPIFKGCFYTHPTEVLKPVSQHPR---DFFSR
270 280 290 300 310
620 630 640 650 660 670
pF1KE0 MADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMFKDKDLTGPMNENHGLNYTPLL
. : . :: .. . :. . : . : ..: . .:
XP_016 LKDGVL--------LGPPGKEGLSVKEPQ--------LVWGGDANRPSAFHKGGSRKGIL
320 330 340 350
680 690 700 710 720 730
pF1KE0 YSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHG
: . . .::.:: . . .: ..: : : : ::..:
XP_016 YPKPKACWVSPMAK----VPAESPTLPPTFP--SSPGLGSKRSLEEEGAAHSGKRLRAVS
360 370 380 390 400 410
740 750 760 770 780 790
pF1KE0 QSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLSRSDPHRCSFSKHHLNPLAD
XP_016 PFLKEADAKKCGAKPAGSGLVSCLLGPALGPVPPEAYRGTMLHCPLNFTGTPGPLKGQAA
420 430 440 450 460 470
>>NP_001306016 (OMIM: 611583) AT-rich interactive domain (647 aa)
initn: 785 init1: 344 opt: 379 Z-score: 268.6 bits: 60.8 E(85289): 3.2e-08
Smith-Waterman score: 550; 30.0% identity (50.2% similar) in 510 aa overlap (290-722:22-500)
260 270 280 290 300 310
pF1KE0 QRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKP--KNNHNCKKVSNEEKPKVAIGE--
: :: :.: . .: :..:. : ::
NP_001 MAAPVKGNRKQSTEGDALDPPASPKPAGKQNGIQNPISLEDSPE-AGGERE
10 20 30 40 50
320 330 340 350 360
pF1KE0 --ECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYET------
. : .::::::.:::.::::.:::::.:.::::::::: ...:..:::.::
NP_001 EEQEREEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELSMALGE
60 70 80 90 100 110
370 380
pF1KE0 -----------------------------------------------ITARRQWKHIYDE
.:.:: ::..:::
NP_001 RIGWPLLEPQSSCQTAVLRVPARAAGAARTPPPGGARRPRPHEVPLQVTGRRLWKNVYDE
120 130 140 150 160 170
390 400 410 420 430
pF1KE0 LGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENSSQEN-------E
:::.:::::::::::::::::.::: : .:::.::::: ::::: . ..:: :
NP_001 LGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENRGDDGATE
180 190 200 210 220 230
440 450 460 470 480 490
pF1KE0 NKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAEVSSEQEKEQETLISQKSIPEPLPAADM
:.. .:. . .: . : : : . : .. ::. : : .:. ..
NP_001 RPKKAKEERRMDQMMPGKTKADAADPAPLPSQE-PPRNSTEQQGLASGSSVSFVGASGCP
240 250 260 270 280
500 510 520 530 540
pF1KE0 KKKIEGYQEFSAKPLASRVDP-EKDNETDQGSNSE--KVAEEAGEKGPTP---PLPSAPL
. . . : : . ..: : . : :. : . ::. ..: : : :
NP_001 EAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQASPAVHLPE
290 300 310 320 330 340
550 560 570 580 590 600
pF1KE0 APEKDSALVPGAS-----KQPLTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPTTQ
.:.. ..:. .. .. : .:.. . . .. : : . .. : . ::
NP_001 SPQSPKGLTENSRHRLTPQEGLQAPGGSLREEAQAGPC-----PAAPIFKGCFYTHPTEV
350 360 370 380 390 400
610 620 630 640 650 660
pF1KE0 PPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMFKDKDL
..:. : . . : . :: .. : :. .. :
NP_001 LKPVSQHPR--DFFSRLKDGVL--------LGPPGKEG--------LSVKEPQLVWGGDA
410 420 430 440
670 680 690 700 710 720
pF1KE0 TGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKL
. : ..: . .:: . . .::.:: : .: ..: : : : ::..:
NP_001 NRPSAFHKGGSRKGILYPKPKACWVSPMAKVPAES----PTLPPTFP--SSPGLGSKRSL
450 460 470 480 490 500
730 740 750 760 770 780
pF1KE0 IARDDLCSSLSQTHHGQSTDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLSRSD
NP_001 EEEGAAHSGKRLRAVSPFLKEADAKKCGAKPAGSGLVSCLLGPALGPVPPEAYRGTMLHC
510 520 530 540 550 560
1188 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:26:05 2016 done: Thu Nov 3 12:26:07 2016
Total Scan time: 16.170 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]