Result of FASTA (omim) for
pF1KE0389
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0389, 836 aa
1>>>pF1KE0389 836 - 836 aa - 836 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7380+/-0.000382; mu= 9.2743+/- 0.024
mean_var=135.4053+/-27.776, 0's: 0 Z-trim(117.3): 4 B-trim: 624 in 1/57
Lambda= 0.110219
statistics sampled from 29166 (29170) to 29166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.342), width: 16
Scan time: 12.110
The best scores are: opt bits E(85289)
NP_073753 (OMIM: 611735) CUB domain-containing pro ( 836) 5639 908.7 0
XP_011532326 (OMIM: 611735) PREDICTED: CUB domain- ( 835) 5621 905.8 0
XP_016862559 (OMIM: 611735) PREDICTED: CUB domain- ( 786) 4469 722.7 1.6e-207
NP_835488 (OMIM: 611735) CUB domain-containing pro ( 343) 2289 375.8 1.8e-103
>>NP_073753 (OMIM: 611735) CUB domain-containing protein (836 aa)
initn: 5639 init1: 5639 opt: 5639 Z-score: 4851.7 bits: 908.7 E(85289): 0
Smith-Waterman score: 5639; 100.0% identity (100.0% similar) in 836 aa overlap (1-836:1-836)
10 20 30 40 50 60
pF1KE0 MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 RYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 RYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 FKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 FKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 TGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 TGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 PRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KFQKGRKDNDSHVYAVIEDTMVYGHLLQDSSGSFLQPEVDTYRPFQGTMGVCPPSPPTIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 KFQKGRKDNDSHVYAVIEDTMVYGHLLQDSSGSFLQPEVDTYRPFQGTMGVCPPSPPTIC
730 740 750 760 770 780
790 800 810 820 830
pF1KE0 SRAPTAKLATEEPPPRSPPESESEPYTFSHPNNGDVSSKDTDIPLLNTQEPMEPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SRAPTAKLATEEPPPRSPPESESEPYTFSHPNNGDVSSKDTDIPLLNTQEPMEPAE
790 800 810 820 830
>>XP_011532326 (OMIM: 611735) PREDICTED: CUB domain-cont (835 aa)
initn: 5619 init1: 5462 opt: 5621 Z-score: 4836.2 bits: 905.8 E(85289): 0
Smith-Waterman score: 5621; 99.9% identity (99.9% similar) in 836 aa overlap (1-836:1-835)
10 20 30 40 50 60
pF1KE0 MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVI
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 MAGLNCGVSIALLGVLLLGAARLPRGA-AFEIALPRESNITVLIKLGTPTLLAKPCYIVI
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 PRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDH
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 RYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSF
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 SYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPY
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 FKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE0 TGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLT
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 PRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 KFQKGRKDNDSHVYAVIEDTMVYGHLLQDSSGSFLQPEVDTYRPFQGTMGVCPPSPPTIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFQKGRKDNDSHVYAVIEDTMVYGHLLQDSSGSFLQPEVDTYRPFQGTMGVCPPSPPTIC
720 730 740 750 760 770
790 800 810 820 830
pF1KE0 SRAPTAKLATEEPPPRSPPESESEPYTFSHPNNGDVSSKDTDIPLLNTQEPMEPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRAPTAKLATEEPPPRSPPESESEPYTFSHPNNGDVSSKDTDIPLLNTQEPMEPAE
780 790 800 810 820 830
>>XP_016862559 (OMIM: 611735) PREDICTED: CUB domain-cont (786 aa)
initn: 4503 init1: 4469 opt: 4469 Z-score: 3846.6 bits: 722.7 E(85289): 1.6e-207
Smith-Waterman score: 4469; 100.0% identity (100.0% similar) in 664 aa overlap (1-664:1-664)
10 20 30 40 50 60
pF1KE0 MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 RYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 FKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 TGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 PRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPK
::::
XP_016 PRTVGKRRQTRAPLWVSTMTTSILRCRGSQKSFRKGERTMTPMCMQSSRTPWYMGICYRI
670 680 690 700 710 720
>>NP_835488 (OMIM: 611735) CUB domain-containing protein (343 aa)
initn: 2289 init1: 2289 opt: 2289 Z-score: 1978.7 bits: 375.8 E(85289): 1.8e-103
Smith-Waterman score: 2289; 99.4% identity (100.0% similar) in 343 aa overlap (1-343:1-343)
10 20 30 40 50 60
pF1KE0 MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 SKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 LNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 GTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 PEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIE
:::::::::::::::::::::::::::::::::::::::::..
NP_835 QPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESSE
310 320 330 340
370 380 390 400 410 420
pF1KE0 PRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDH
836 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:49:54 2016 done: Thu Nov 3 12:49:55 2016
Total Scan time: 12.110 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]