FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0357, 601 aa
  1>>>pF1KE0357 601 - 601 aa - 601 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6293+/-0.00103; mu= 13.0215+/- 0.062
 mean_var=96.5072+/-19.357, 0's: 0 Z-trim(106.0): 26  B-trim: 0 in 0/51
 Lambda= 0.130555
 statistics sampled from 8726 (8734) to 8726 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.268), width:  16
 Scan time:  3.230

The best scores are:                                      opt bits E(32554)
CCDS34872.1 ESCO2 gene_id:157570|Hs108|chr8        ( 601) 3999 764.0       0
CCDS32800.1 ESCO1 gene_id:114799|Hs108|chr18       ( 840) 1055 209.5 1.4e-53


>>CCDS34872.1 ESCO2 gene_id:157570|Hs108|chr8             (601 aa)
 initn: 3999 init1: 3999 opt: 3999  Z-score: 4074.5  bits: 764.0 E(32554):    0
Smith-Waterman score: 3999; 100.0% identity (100.0% similar) in 601 aa overlap (1-601:1-601)

               10        20        30        40        50        60
pF1KE0 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 KTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKEN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 NCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 NTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 FISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 FRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFN
              550       560       570       580       590       600

        
pF1KE0 S
       :
CCDS34 S
        

>>CCDS32800.1 ESCO1 gene_id:114799|Hs108|chr18            (840 aa)
 initn: 1000 init1: 602 opt: 1055  Z-score: 1075.5  bits: 209.5 E(32554): 1.4e-53
Smith-Waterman score: 1068; 37.9% identity (66.9% similar) in 525 aa overlap (104-599:322-833)

            80        90       100       110       120         130 
pF1KE0 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV
                                     ...:. ...  :.:   :  :.  .. . .
CCDS32 LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL
             300       310       320       330       340       350 

             140       150         160         170       180       
pF1KE0 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE
        .:..:.  :     .. :. :. :::.   :. ::  :.:    :  . : :.  :.  
CCDS32 HQKETNQDVQ---CNRFFPS-RKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKL
             360           370       380       390       400       

        190         200          210       220       230       240 
pF1KE0 NNSNAPRV--LSQKIKPQVTLQGGA---AFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI
       ... .:..  :  ...: .  .      . :.  :   :. . ..:    . .. .:: .
CCDS32 DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV
       410       420       430       440       450           460   

                     250       260       270       280       290   
pF1KE0 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR
       . .:.        : . :.  .:..  :.   :....: .. :::.::  . .... .. 
CCDS32 KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN-
           470       480       490       500       510       520   

           300       310         320       330       340           
pF1KE0 VSSKEHKVDKNEAFSSEDSL--GENKTISPKSTVYPIFSASSVNSKRSLGEE---QFSVG
         :  ..:    .. :. ..  ::::  .     . :.: ..  :: : ..:   . :. 
CCDS32 --SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQT--SKSSDNRETPRNHSLP
              530       540       550       560         570        

      350       360       370       380       390       400        
pF1KE0 SVNFMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHV
       . :   . .: :. . ... :  . :::::::::.:::. :. :::.::::::::: ::.
CCDS32 KCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHL
      580       590       600       610       620       630        

      410       420       430       440       450       460        
pF1KE0 QHHHRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQV
         :..:. ..:::::::::..::. ::.:..:::.::..:.:::....:.:::.:::::.
CCDS32 LFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQA
      640       650       660       670       680       690        

      470       480       490       500           510       520    
pF1KE0 VPKCPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQC
          : .. ::.::::..:.:::::::: :. ..::. :  :.  . :     :  .:: :
CCDS32 PLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCC
      700       710       720       730       740       750        

          530       540       550       560       570       580    
pF1KE0 SDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLF
       : .::::.::::::::: . :::.:: :... ::. :..: .:: .::::::::::::::
CCDS32 STLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLF
      760       770       780       790       800       810        

          590       600      
pF1KE0 ATKYCNTPNFLVYNFNS     
       ::.::.: .::::::       
CCDS32 ATQYCGTGQFLVYNFINGQNST
      820       830       840




601 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:19:06 2016 done: Thu Nov  3 14:19:06 2016
 Total Scan time:  3.230 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]