FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0175, 301 aa
  1>>>pF1KE0175 301 - 301 aa - 301 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3838+/-0.000282; mu= 12.9661+/- 0.018
 mean_var=116.3281+/-23.785, 0's: 0 Z-trim(121.9): 2  B-trim: 1229 in 1/53
 Lambda= 0.118914
 statistics sampled from 39090 (39092) to 39090 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.458), width:  16
 Scan time:  8.960

The best scores are:                                      opt bits E(85289)
NP_001129516 (OMIM: 614792) transmembrane and ubiq ( 246)  490 93.9 3.3e-19
NP_113622 (OMIM: 614792) transmembrane and ubiquit ( 246)  490 93.9 3.3e-19


>>NP_001129516 (OMIM: 614792) transmembrane and ubiquiti  (246 aa)
 initn: 582 init1: 279 opt: 490  Z-score: 465.8  bits: 93.9 E(85289): 3.3e-19
Smith-Waterman score: 574; 39.7% identity (64.4% similar) in 295 aa overlap (6-299:1-244)

               10        20        30        40        50        60
pF1KE0 MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLH
            .:::::::.:: :. .:.. .:.:.:::.::..:..:                  
NP_001      MTLIEGVGDEVTVLFSVLACLLVLALAWVSTHTAEGG------------------
                    10        20        30                         

               70        80        90       100        110         
pF1KE0 LGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDST-GEAGAGGGVEPSLEHLLD
           : :      :.:.  : ::. .      :. .  ::  :::   :.  :::.:   
NP_001 ----DPL------PQPSGTPTPSQPS------AAMAATDSMRGEAP--GAETPSLRHR-G
            40              50              60          70         

     120       130       140       150       160       170         
pF1KE0 IQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGAL
         . :. ..:  ...: ::    ::   :  :  ...:::::::.:..: : :.::.:.:
NP_001 QAAQPEPSTGF-TATPPAP----DS---PQEP--LVLRLKFLNDSEQVARAWPHDTIGSL
       80         90              100         110       120        

     180       190       200       210       220       230         
pF1KE0 KSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPS
       :   :::.:.:..:::::.:: : ..:: ::..  :::.::: :   . : ::     : 
NP_001 KRTQFPGREQQVRLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVS---TRV-GPPNPPCPP
      130       140       150       160       170           180    

     240       250       260       270       280       290         
pF1KE0 ATEPPRLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMY
       ..::   :...:::..:....:: ..:: .:.:: ::   ::..:.: :...:.:.:.::
NP_001 GSEPGPSGLEIGSLLLPLLLLLLLLLWYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMY
          190       200       210       220       230       240    

     300 
pF1KE0 GR
         
NP_001 RP
         

>>NP_113622 (OMIM: 614792) transmembrane and ubiquitin-l  (246 aa)
 initn: 582 init1: 279 opt: 490  Z-score: 465.8  bits: 93.9 E(85289): 3.3e-19
Smith-Waterman score: 574; 39.7% identity (64.4% similar) in 295 aa overlap (6-299:1-244)

               10        20        30        40        50        60
pF1KE0 MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLH
            .:::::::.:: :. .:.. .:.:.:::.::..:..:                  
NP_113      MTLIEGVGDEVTVLFSVLACLLVLALAWVSTHTAEGG------------------
                    10        20        30                         

               70        80        90       100        110         
pF1KE0 LGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDST-GEAGAGGGVEPSLEHLLD
           : :      :.:.  : ::. .      :. .  ::  :::   :.  :::.:   
NP_113 ----DPL------PQPSGTPTPSQPS------AAMAATDSMRGEAP--GAETPSLRHR-G
            40              50              60          70         

     120       130       140       150       160       170         
pF1KE0 IQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGAL
         . :. ..:  ...: ::    ::   :  :  ...:::::::.:..: : :.::.:.:
NP_113 QAAQPEPSTGF-TATPPAP----DS---PQEP--LVLRLKFLNDSEQVARAWPHDTIGSL
       80         90              100         110       120        

     180       190       200       210       220       230         
pF1KE0 KSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPS
       :   :::.:.:..:::::.:: : ..:: ::..  :::.::: :   . : ::     : 
NP_113 KRTQFPGREQQVRLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVS---TRV-GPPNPPCPP
      130       140       150       160       170           180    

     240       250       260       270       280       290         
pF1KE0 ATEPPRLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMY
       ..::   :...:::..:....:: ..:: .:.:: ::   ::..:.: :...:.:.:.::
NP_113 GSEPGPSGLEIGSLLLPLLLLLLLLLWYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMY
          190       200       210       220       230       240    

     300 
pF1KE0 GR
         
NP_113 RP
         




301 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:42:24 2016 done: Thu Nov  3 22:42:25 2016
 Total Scan time:  8.960 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]