FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0175, 301 aa
  1>>>pF1KE0175 301 - 301 aa - 301 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5405+/-0.000665; mu= 12.1961+/- 0.041
 mean_var=117.3191+/-23.305, 0's: 0 Z-trim(114.6): 5  B-trim: 8 in 1/51
 Lambda= 0.118410
 statistics sampled from 15193 (15198) to 15193 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.467), width:  16
 Scan time:  3.050

The best scores are:                                      opt bits E(32554)
CCDS11479.1 TMUB2 gene_id:79089|Hs108|chr17        ( 301) 1972 346.8 1.2e-95
CCDS54134.1 TMUB2 gene_id:79089|Hs108|chr17        ( 321) 1972 346.8 1.2e-95
CCDS82137.1 TMUB2 gene_id:79089|Hs108|chr17        ( 264) 1205 215.7 2.9e-56
CCDS5920.1 TMUB1 gene_id:83590|Hs108|chr7          ( 246)  490 93.6 1.6e-19


>>CCDS11479.1 TMUB2 gene_id:79089|Hs108|chr17             (301 aa)
 initn: 1972 init1: 1972 opt: 1972  Z-score: 1830.9  bits: 346.8 E(32554): 1.2e-95
Smith-Waterman score: 1972; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:1-301)

               10        20        30        40        50        60
pF1KE0 MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 QGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPSA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 TEPPRLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYG
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYG
              250       260       270       280       290       300

        
pF1KE0 R
       :
CCDS11 R
        

>>CCDS54134.1 TMUB2 gene_id:79089|Hs108|chr17             (321 aa)
 initn: 1972 init1: 1972 opt: 1972  Z-score: 1830.5  bits: 346.8 E(32554): 1.2e-95
Smith-Waterman score: 1972; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:21-321)

                                   10        20        30        40
pF1KE0                     MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVAD
                           ::::::::::::::::::::::::::::::::::::::::
CCDS54 MISRHLQNNLMSVDPASSQAMELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVAD
               10        20        30        40        50        60

               50        60        70        80        90       100
pF1KE0 SGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDS
               70        80        90       100       110       120

              110       120       130       140       150       160
pF1KE0 TGEAGAGGGVEPSLEHLLDIQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TGEAGAGGGVEPSLEHLLDIQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKF
              130       140       150       160       170       180

              170       180       190       200       210       220
pF1KE0 LNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHC
              190       200       210       220       230       240

              230       240       250       260       270       280
pF1KE0 HRSPPGSAVPGPSASLAPSATEPPRLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPA
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
CCDS54 HRSPPGSAVPGPSASLAPSATEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPA
              250       260       270       280       290       300

              290       300 
pF1KE0 TVSLVGVTVFFSFLVFGMYGR
       :::::::::::::::::::::
CCDS54 TVSLVGVTVFFSFLVFGMYGR
              310       320 

>>CCDS82137.1 TMUB2 gene_id:79089|Hs108|chr17             (264 aa)
 initn: 1201 init1: 1201 opt: 1205  Z-score: 1123.5  bits: 215.7 E(32554): 2.9e-56
Smith-Waterman score: 1643; 87.4% identity (87.4% similar) in 301 aa overlap (1-301:1-264)

               10        20        30        40        50        60
pF1KE0 MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDI
       :::::::::::::::::::::::::                                   
CCDS82 LGHVDHLVAGQGNPEPTELPHPSEG-----------------------------------
               70        80                                        

              130       140       150       160       170       180
pF1KE0 QGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALK
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 --LPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALK
            90       100       110       120       130       140   

              190       200       210       220       230       240
pF1KE0 SKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPSA
           150       160       170       180       190       200   

              250       260       270       280       290       300
pF1KE0 TEPPRLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYG
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYG
           210       220       230       240       250       260   

        
pF1KE0 R
       :
CCDS82 R
        

>>CCDS5920.1 TMUB1 gene_id:83590|Hs108|chr7               (246 aa)
 initn: 582 init1: 279 opt: 490  Z-score: 463.8  bits: 93.6 E(32554): 1.6e-19
Smith-Waterman score: 574; 39.7% identity (64.4% similar) in 295 aa overlap (6-299:1-244)

               10        20        30        40        50        60
pF1KE0 MELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLH
            .:::::::.:: :. .:.. .:.:.:::.::..:..:                  
CCDS59      MTLIEGVGDEVTVLFSVLACLLVLALAWVSTHTAEGG------------------
                    10        20        30                         

               70        80        90       100        110         
pF1KE0 LGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDST-GEAGAGGGVEPSLEHLLD
           : :      :.:.  : ::. .      :. .  ::  :::   :.  :::.:   
CCDS59 ----DPL------PQPSGTPTPSQPS------AAMAATDSMRGEAP--GAETPSLRHR-G
            40              50              60          70         

     120       130       140       150       160       170         
pF1KE0 IQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGAL
         . :. ..:  ...: ::    ::   :  :  ...:::::::.:..: : :.::.:.:
CCDS59 QAAQPEPSTGF-TATPPAP----DS---PQEP--LVLRLKFLNDSEQVARAWPHDTIGSL
       80         90              100         110       120        

     180       190       200       210       220       230         
pF1KE0 KSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPS
       :   :::.:.:..:::::.:: : ..:: ::..  :::.::: :   . : ::     : 
CCDS59 KRTQFPGREQQVRLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVS---TRV-GPPNPPCPP
      130       140       150       160       170           180    

     240       250       260       270       280       290         
pF1KE0 ATEPPRLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMY
       ..::   :...:::..:....:: ..:: .:.:: ::   ::..:.: :...:.:.:.::
CCDS59 GSEPGPSGLEIGSLLLPLLLLLLLLLWYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMY
          190       200       210       220       230       240    

     300 
pF1KE0 GR
         
CCDS59 RP
         




301 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:42:23 2016 done: Thu Nov  3 22:42:23 2016
 Total Scan time:  3.050 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]