FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0142, 179 aa
  1>>>pF1KE0142 179 - 179 aa - 179 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2176+/-0.000288; mu= 13.8740+/- 0.018
 mean_var=69.5681+/-13.876, 0's: 0 Z-trim(118.0): 9  B-trim: 0 in 0/52
 Lambda= 0.153769
 statistics sampled from 30480 (30489) to 30480 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.357), width:  16
 Scan time:  5.950

The best scores are:                                      opt bits E(85289)
NP_079412 (OMIM: 165300,258501,606580) optic atrop ( 179) 1182 270.4 1.1e-72
NP_001017989 (OMIM: 165300,258501,606580) optic at ( 180)  877 202.8 2.5e-52
XP_006723466 (OMIM: 165300,258501,606580) PREDICTE ( 126)  825 191.1 5.6e-49


>>NP_079412 (OMIM: 165300,258501,606580) optic atrophy 3  (179 aa)
 initn: 1182 init1: 1182 opt: 1182  Z-score: 1426.1  bits: 270.4 E(85289): 1.1e-72
Smith-Waterman score: 1182; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)

               10        20        30        40        50        60
pF1KE0 MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 MGFRGTVIKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQAQQRHKEEEQRAAWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MGFRGTVIKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQAQQRHKEEEQRAAWN
               70        80        90       100       110       120

              130       140       150       160       170         
pF1KE0 ALRDEVGHLALALEALQAQVQAAPPQGALEELRTELQEVRAQLCNPGRSASHAVPASKK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ALRDEVGHLALALEALQAQVQAAPPQGALEELRTELQEVRAQLCNPGRSASHAVPASKK
              130       140       150       160       170         

>>NP_001017989 (OMIM: 165300,258501,606580) optic atroph  (180 aa)
 initn: 865 init1: 865 opt: 877  Z-score: 1060.4  bits: 202.8 E(85289): 2.5e-52
Smith-Waterman score: 877; 77.3% identity (90.1% similar) in 181 aa overlap (1-179:1-180)

               10        20        30        40        50        60
pF1KE0 MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRI
       :::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_001 MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWLEMRTKMRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 MGFRGTVIKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQAQQRHKEEEQRAAWN
       ::: ...:::::: ::::::::::::. :::.. .::.::::::: :::.::.:.:.: .
NP_001 MGFNAAAIKPLNEGAAAELGAELLGEGIIFITACSCLMLEYWRHQLQQRRKEKERRVARE
               70        80        90       100       110       120

              130       140       150       160         170        
pF1KE0 ALRDEVGHLALALEALQAQVQAAPPQGALEELRTELQEVRAQLC--NPGRSASHAVPASK
       ::: :::::.:::: :::::::.  : ::::::..::::::.::  .:   :  ..:::.
NP_001 ALRGEVGHLGLALEELQAQVQATSTQLALEELRAQLQEVRAHLCLRDPP-PAPPVAPASE
              130       140       150       160        170         

        
pF1KE0 K
       :
NP_001 K
     180

>>XP_006723466 (OMIM: 165300,258501,606580) PREDICTED: o  (126 aa)
 initn: 825 init1: 825 opt: 825  Z-score: 1000.3  bits: 191.1 E(85289): 5.6e-49
Smith-Waterman score: 825; 100.0% identity (100.0% similar) in 126 aa overlap (54-179:1-126)

            30        40        50        60        70        80   
pF1KE0 ANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRIMGFRGTVIKPLNEEAAAELGAEL
                                     ::::::::::::::::::::::::::::::
XP_006                               MRTKMRIMGFRGTVIKPLNEEAAAELGAEL
                                             10        20        30

            90       100       110       120       130       140   
pF1KE0 LGEATIFIVGGGCLVLEYWRHQAQQRHKEEEQRAAWNALRDEVGHLALALEALQAQVQAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGEATIFIVGGGCLVLEYWRHQAQQRHKEEEQRAAWNALRDEVGHLALALEALQAQVQAA
               40        50        60        70        80        90

           150       160       170         
pF1KE0 PPQGALEELRTELQEVRAQLCNPGRSASHAVPASKK
       ::::::::::::::::::::::::::::::::::::
XP_006 PPQGALEELRTELQEVRAQLCNPGRSASHAVPASKK
              100       110       120      




179 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 00:40:33 2016 done: Fri Nov  4 00:40:34 2016
 Total Scan time:  5.950 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]