Result of FASTA (ccds) for
pF1KE0136
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0136, 302 aa
1>>>pF1KE0136 302 - 302 aa - 302 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7838+/-0.000917; mu= 12.1944+/- 0.055
mean_var=57.1731+/-11.123, 0's: 0 Z-trim(104.7): 16 B-trim: 0 in 0/48
Lambda= 0.169620
statistics sampled from 8034 (8041) to 8034 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.247), width: 16
Scan time: 2.190
The best scores are: opt bits E(32554)
CCDS14747.1 DNASE1L1 gene_id:1774|Hs108|chrX ( 302) 1956 486.9 7.9e-138
CCDS2886.1 DNASE1L3 gene_id:1776|Hs108|chr3 ( 305) 782 199.6 2.4e-51
CCDS10507.1 DNASE1 gene_id:1773|Hs108|chr16 ( 282) 626 161.4 7e-40
CCDS58836.1 DNASE1L3 gene_id:1776|Hs108|chr3 ( 275) 545 141.6 6.3e-34
CCDS42105.1 DNASE1L2 gene_id:1775|Hs108|chr16 ( 299) 403 106.9 2e-23
>>CCDS14747.1 DNASE1L1 gene_id:1774|Hs108|chrX (302 aa)
initn: 1956 init1: 1956 opt: 1956 Z-score: 2588.0 bits: 486.9 E(32554): 7.9e-138
Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302)
10 20 30 40 50 60
pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
CCDS14 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP
250 260 270 280 290 300
pF1KE0 AA
::
CCDS14 AA
>>CCDS2886.1 DNASE1L3 gene_id:1776|Hs108|chr3 (305 aa)
initn: 701 init1: 406 opt: 782 Z-score: 1035.2 bits: 199.6 E(32554): 2.4e-51
Smith-Waterman score: 782; 41.3% identity (76.7% similar) in 288 aa overlap (7-287:9-296)
10 20 30 40 50
pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEV
::.:. ..: :.:::.::.. . .: ...::..:... ::::....:.
CCDS28 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 VDSSGSAIPLLLRELNRFDGSG-PYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYN
::.. :.:...::: . : :. . : .:::.:: : :...:. . ..: :: :.
CCDS28 KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 D-ED---DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQ
: .: :::.:::::. :. : ... ..:..::::::.. ::.. : .:. .:...:.
CCDS28 DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 SKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHG
... :..::::: :. . :: ...:::.: : :.:.: :::::. ::.:.:::.::.:
CCDS28 AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 ERCRSLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLP
.. : . .. ..::: ...:::::::..:::.::: .:. :.: . . :.:.
CCDS28 QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
250 260 270 280 290 300
300
pF1KE0 SLLSPQLCPAA
CCDS28 KSKRS
>>CCDS10507.1 DNASE1 gene_id:1773|Hs108|chr16 (282 aa)
initn: 562 init1: 275 opt: 626 Z-score: 829.5 bits: 161.4 E(32554): 7e-40
Smith-Waterman score: 626; 39.1% identity (68.8% similar) in 276 aa overlap (6-273:9-282)
10 20 30 40 50
pF1KE0 MHYPTALLFLI-LANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQ
::: : : .:: ...: ::: : . .:.. ... .:.::.: :: ..:
CCDS10 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 EVVDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVY
:: :: .:. :: .::. :. : . : :::..: : :.. :: ......:: :
CCDS10 EVRDSHLTAVGKLLDNLNQ-DAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYY
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 NDE-----DDVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQH
.: .:.: ::: ...: . . ...::::..: . :..:::::.:.:...
CCDS10 DDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 WQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVL
: .::.:.::::: :. . .. ....: : : :.:.: :. :::. . :::.:::.:.
CCDS10 WGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTA-TPTHCAYDRIVV
180 190 200 210 220 230
240 250 260 270 280
pF1KE0 HGERCRSLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLL
: :. . .: :.: ... :... : ::::::::: ::
CCDS10 AGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
240 250 260 270 280
290 300
pF1KE0 LPSLLSPQLCPAA
>>CCDS58836.1 DNASE1L3 gene_id:1776|Hs108|chr3 (275 aa)
initn: 701 init1: 406 opt: 545 Z-score: 722.6 bits: 141.6 E(32554): 6.3e-34
Smith-Waterman score: 670; 38.4% identity (70.8% similar) in 284 aa overlap (7-287:9-266)
10 20 30 40 50
pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEV
::.:. ..: :.:::.::.. . .: ...::..:... ::::....:.
CCDS58 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 VDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYND
::.. :.:...::: : : ::.. . :.:
CCDS58 KDSNNRICPILMEKLNR---------------------EKLVSVKRSYHY-----HDYQD
70 80 90
120 130 140 150 160 170
pF1KE0 ED-DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDV
: :::.:::::. :. : ... ..:..::::::.. ::.. : .:. .:...:....
CCDS58 GDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWKAENF
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 ILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCR
:..::::: :. . :: ...:::.: : :.:.: :::::. ::.:.:::.::.:..
CCDS58 IFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRGQEIV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 SLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLS
: . .. ..::: ...:::::::..:::.::: .:. :.: . . :.:.
CCDS58 SSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKTKSKR
220 230 240 250 260 270
300
pF1KE0 PQLCPAA
CCDS58 S
>>CCDS42105.1 DNASE1L2 gene_id:1775|Hs108|chr16 (299 aa)
initn: 633 init1: 254 opt: 403 Z-score: 534.1 bits: 106.9 E(32554): 2e-23
Smith-Waterman score: 657; 39.8% identity (64.9% similar) in 299 aa overlap (1-274:1-297)
10 20 30 40 50
pF1KE0 MHYPTALL---FLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQE
: : ::: . . : :. :.:: ::: : . .::. . ...::: :. ..::
CCDS42 MGGPRALLAALWALEAAGTAALRIGAFNIQSFGDSKVSDPACGSIIAKILAGYDLALVQE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 VVDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYN
: : . ::. :....: . :: .:: :::. : : :.. ::. ..:...:.:
CCDS42 VRDPDLSAVSALMEQINSVS-EHEYSFVSSQPLGRDQYKEMYLFVYRKDAVSVVDTYLYP
70 80 90 100 110
120 130 140 150
pF1KE0 DEDDVFAREPFVAQFSLPSN-----VLPS---------------LVLVPLHTTPKAVEKE
: .:::.:::::..:: :.. ::: :::.:::..:. . :
CCDS42 DPEDVFSREPFVVKFSAPGTGERAPPLPSRRALTPPPLPAAAQNLVLIPLHAAPHQAVAE
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 LNALYDVFLEVSQHWQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTT
..:::::.:.: ..: . :...::::::::. . . ..::. :.:.: :. :::
CCDS42 IDALYDVYLDVIDKWGTDDMLFLGDFNADCSYVRAQDWAAIRLRSSEVFKWLIPDSADTT
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE0 VRASTHCTYDRVVLHGERCRSLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLS
: ... :.:::.: : : : : ..:.. :: : : . .:: ::::.:::: ::.
CCDS42 V-GNSDCAYDRIVACGARLRRSLKPQSATVHDFQEEFGLDQTQALAISDHFPVEVTLKFH
240 250 260 270 280 290
280 290 300
pF1KE0 QAHSVQPLSLTVLLLPSLLSPQLCPAA
CCDS42 R
302 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:06:20 2016 done: Fri Nov 4 01:06:20 2016
Total Scan time: 2.190 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]