Result of FASTA (omim) for
pF1KE0126
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0126, 125 aa
1>>>pF1KE0126 125 - 125 aa - 125 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2197+/-0.00034; mu= 10.5407+/- 0.021
mean_var=53.1367+/-10.604, 0's: 0 Z-trim(113.5): 15 B-trim: 268 in 1/52
Lambda= 0.175945
statistics sampled from 22865 (22878) to 22865 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.268), width: 16
Scan time: 4.190
The best scores are: opt bits E(85289)
NP_073729 (OMIM: 609604) microtubule-associated pr ( 125) 802 211.2 3.6e-55
NP_115903 (OMIM: 601242) microtubule-associated pr ( 121) 669 177.4 5.1e-45
XP_011527387 (OMIM: 601242) PREDICTED: microtubule ( 182) 669 177.4 7.4e-45
XP_011527385 (OMIM: 601242) PREDICTED: microtubule ( 223) 669 177.5 8.9e-45
XP_011527386 (OMIM: 601242) PREDICTED: microtubule ( 223) 669 177.5 8.9e-45
NP_852610 (OMIM: 601242) microtubule-associated pr ( 125) 599 159.6 1.2e-39
XP_005273196 (OMIM: 609605) PREDICTED: microtubule ( 147) 443 120.1 1.1e-27
NP_001004343 (OMIM: 609605) microtubule-associated ( 147) 443 120.1 1.1e-27
NP_009216 (OMIM: 607452) gamma-aminobutyric acid r ( 117) 307 85.5 2.3e-17
NP_113600 (OMIM: 607420) gamma-aminobutyric acid r ( 117) 255 72.3 2.1e-13
NP_009209 (OMIM: 605125) gamma-aminobutyric acid r ( 117) 247 70.3 8.7e-13
XP_005253401 (OMIM: 607420) PREDICTED: gamma-amino ( 146) 198 57.9 5.9e-09
>>NP_073729 (OMIM: 609604) microtubule-associated protei (125 aa)
initn: 802 init1: 802 opt: 802 Z-score: 1111.4 bits: 211.2 E(85289): 3.6e-55
Smith-Waterman score: 802; 100.0% identity (100.0% similar) in 125 aa overlap (1-125:1-125)
10 20 30 40 50 60
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
70 80 90 100 110 120
pF1KE0 MKLSV
:::::
NP_073 MKLSV
>>NP_115903 (OMIM: 601242) microtubule-associated protei (121 aa)
initn: 669 init1: 669 opt: 669 Z-score: 929.2 bits: 177.4 E(85289): 5.1e-45
Smith-Waterman score: 669; 82.5% identity (95.0% similar) in 120 aa overlap (1-120:1-120)
10 20 30 40 50 60
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
:::.. :::::.: .: ..:. ::.:::.:::::::::::::::::::::::::::::::
NP_115 MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
:::.:::::::::: .:::::::: ::::::::::...::.:::::::::::::::::::
NP_115 SELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFG
70 80 90 100 110 120
pF1KE0 MKLSV
NP_115 F
>>XP_011527387 (OMIM: 601242) PREDICTED: microtubule-ass (182 aa)
initn: 669 init1: 669 opt: 669 Z-score: 926.3 bits: 177.4 E(85289): 7.4e-45
Smith-Waterman score: 669; 82.5% identity (95.0% similar) in 120 aa overlap (1-120:62-181)
10 20 30
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTK
:::.. :::::.: .: ..:. ::.:::.:
XP_011 REARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE0 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVS
:::::::::::::::::::::::::::::::::.:::::::::: .:::::::: :::::
XP_011 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVS
100 110 120 130 140 150
100 110 120
pF1KE0 VSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV
:::::...::.:::::::::::::::::::
XP_011 VSTPIADIYEQEKDEDGFLYMVYASQETFGF
160 170 180
>>XP_011527385 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 669 init1: 669 opt: 669 Z-score: 924.8 bits: 177.5 E(85289): 8.9e-45
Smith-Waterman score: 669; 82.5% identity (95.0% similar) in 120 aa overlap (1-120:103-222)
10 20 30
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTK
:::.. :::::.: .: ..:. ::.:::.:
XP_011 REARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSK
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVS
:::::::::::::::::::::::::::::::::.:::::::::: .:::::::: :::::
XP_011 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVS
140 150 160 170 180 190
100 110 120
pF1KE0 VSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV
:::::...::.:::::::::::::::::::
XP_011 VSTPIADIYEQEKDEDGFLYMVYASQETFGF
200 210 220
>>XP_011527386 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 669 init1: 669 opt: 669 Z-score: 924.8 bits: 177.5 E(85289): 8.9e-45
Smith-Waterman score: 669; 82.5% identity (95.0% similar) in 120 aa overlap (1-120:103-222)
10 20 30
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTK
:::.. :::::.: .: ..:. ::.:::.:
XP_011 REARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSK
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVS
:::::::::::::::::::::::::::::::::.:::::::::: .:::::::: :::::
XP_011 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVS
140 150 160 170 180 190
100 110 120
pF1KE0 VSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV
:::::...::.:::::::::::::::::::
XP_011 VSTPIADIYEQEKDEDGFLYMVYASQETFGF
200 210 220
>>NP_852610 (OMIM: 601242) microtubule-associated protei (125 aa)
initn: 599 init1: 599 opt: 599 Z-score: 833.0 bits: 159.6 E(85289): 1.2e-39
Smith-Waterman score: 599; 85.7% identity (96.2% similar) in 105 aa overlap (16-120:20-124)
10 20 30 40 50
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPD
: ..:. ::.:::.:::::::::::::::::::::::::::
NP_852 MKMRFFSSPCGKAAVDPADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 HVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQ
:::::::.:::::::::: .:::::::: ::::::::::...::.:::::::::::::::
NP_852 HVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQ
70 80 90 100 110 120
120
pF1KE0 ETFGMKLSV
::::
NP_852 ETFGF
>>XP_005273196 (OMIM: 609605) PREDICTED: microtubule-ass (147 aa)
initn: 443 init1: 443 opt: 443 Z-score: 617.8 bits: 120.1 E(85289): 1.1e-27
Smith-Waterman score: 443; 55.0% identity (84.2% similar) in 120 aa overlap (1-120:7-126)
10 20 30 40 50
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLV
.:: . ::::... : :.: :: . :.::::..::: : :: ::::::::
XP_005 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 PDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYA
:....:.....::: :. : :..::.::::..:.::.:. ..:.:.. ::::::.::.::
XP_005 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
120
pF1KE0 SQETFGMKLSV
::::::
XP_005 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>NP_001004343 (OMIM: 609605) microtubule-associated pro (147 aa)
initn: 443 init1: 443 opt: 443 Z-score: 617.8 bits: 120.1 E(85289): 1.1e-27
Smith-Waterman score: 443; 55.0% identity (84.2% similar) in 120 aa overlap (1-120:7-126)
10 20 30 40 50
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLV
.:: . ::::... : :.: :: . :.::::..::: : :: ::::::::
NP_001 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 PDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYA
:....:.....::: :. : :..::.::::..:.::.:. ..:.:.. ::::::.::.::
NP_001 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
120
pF1KE0 SQETFGMKLSV
::::::
NP_001 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>NP_009216 (OMIM: 607452) gamma-aminobutyric acid recep (117 aa)
initn: 303 init1: 118 opt: 307 Z-score: 432.9 bits: 85.5 E(85289): 2.3e-17
Smith-Waterman score: 307; 39.5% identity (81.6% similar) in 114 aa overlap (7-120:5-116)
10 20 30 40 50 60
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
::. ...:.: . :: ..: ..:::.:. .: .:. .:: :.:::. ...
NP_009 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSG-SQIVDIDKRKYLVPSDITV
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
.... :::.:.:: ...:.::.:. ... . : ....::.:::::::::..:....:::
NP_009 AQFMWIIRKRIQLPSEKAIFLFVD-KTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFG
60 70 80 90 100 110
pF1KE0 MKLSV
NP_009 F
>>NP_113600 (OMIM: 607420) gamma-aminobutyric acid recep (117 aa)
initn: 244 init1: 113 opt: 255 Z-score: 361.5 bits: 72.3 E(85289): 2.1e-13
Smith-Waterman score: 255; 32.5% identity (78.9% similar) in 114 aa overlap (7-120:5-116)
10 20 30 40 50 60
pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
.:. . :: : .. . ::...: ..:::.:. . ..: ::: :.:::. ...
NP_113 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAP-KARVPDLDKRKYLVPSDLTV
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
... .::.:..: ..:.:..:: ... .:. ....::....:: :::..:... ..:
NP_113 GQFYFLIRKRIHLRPEDALFFFVN-NTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYG
60 70 80 90 100 110
pF1KE0 MKLSV
NP_113 K
125 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:55:31 2016 done: Fri Nov 4 01:55:32 2016
Total Scan time: 4.190 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]