Result of FASTA (omim) for
pF1KE0054
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0054, 1013 aa
1>>>pF1KE0054 1013 - 1013 aa - 1013 aa
Library: /omim/omim.rfq.tfa
63214209 residues in 88908 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1839+/-0.000362; mu= 13.1758+/- 0.023
mean_var=109.6878+/-22.147, 0's: 0 Z-trim(115.8): 72 B-trim: 367 in 2/52
Lambda= 0.122460
statistics sampled from 26976 (27048) to 26976 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.304), width: 16
Scan time: 12.140
The best scores are: opt bits E(88908)
NP_958831 (OMIM: 604249) reticulon-3 isoform b [Ho (1013) 6495 1158.9 0
NP_001252518 (OMIM: 604249) reticulon-3 isoform e (1032) 6189 1104.8 0
XP_011543032 (OMIM: 604249) PREDICTED: reticulon-3 (1037) 5978 1067.6 0
NP_001252519 (OMIM: 604249) reticulon-3 isoform f ( 920) 5577 996.7 0
XP_016872580 (OMIM: 604249) PREDICTED: reticulon-3 ( 880) 5022 898.6 0
XP_016872581 (OMIM: 604249) PREDICTED: reticulon-3 ( 848) 5021 898.4 0
NP_958832 (OMIM: 604249) reticulon-3 isoform c [Ho ( 255) 1172 218.2 4.7e-56
NP_006045 (OMIM: 604249) reticulon-3 isoform a [Ho ( 236) 1169 217.7 6.3e-56
XP_011543033 (OMIM: 604249) PREDICTED: reticulon-3 ( 260) 961 181.0 7.9e-45
NP_958833 (OMIM: 604249) reticulon-3 isoform d [Ho ( 241) 958 180.4 1.1e-44
NP_001308833 (OMIM: 604475) reticulon-4 isoform E ( 986) 801 152.9 8.2e-36
NP_001308792 (OMIM: 604475) reticulon-4 isoform E ( 986) 801 152.9 8.2e-36
NP_001308790 (OMIM: 604475) reticulon-4 isoform E ( 986) 801 152.9 8.2e-36
XP_016860007 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 801 152.9 8.2e-36
NP_001308791 (OMIM: 604475) reticulon-4 isoform E ( 986) 801 152.9 8.2e-36
XP_005264491 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 801 152.9 8.2e-36
NP_001308789 (OMIM: 604475) reticulon-4 isoform E ( 986) 801 152.9 8.2e-36
XP_016860008 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 801 152.9 8.2e-36
NP_997404 (OMIM: 604475) reticulon-4 isoform E [Ho ( 986) 801 152.9 8.2e-36
NP_001308788 (OMIM: 604475) reticulon-4 isoform E ( 986) 801 152.9 8.2e-36
NP_065393 (OMIM: 604475) reticulon-4 isoform A [Ho (1192) 801 152.9 9.7e-36
NP_008939 (OMIM: 604475) reticulon-4 isoform C [Ho ( 199) 785 149.8 1.4e-35
NP_997403 (OMIM: 604475) reticulon-4 isoform D [Ho ( 392) 788 150.5 1.8e-35
NP_722550 (OMIM: 604475) reticulon-4 isoform B [Ho ( 373) 785 149.9 2.5e-35
XP_016877067 (OMIM: 600865) PREDICTED: reticulon-1 ( 193) 760 145.4 3e-34
NP_996734 (OMIM: 600865) reticulon-1 isoform C [Ho ( 208) 760 145.4 3.2e-34
NP_066959 (OMIM: 600865) reticulon-1 isoform A [Ho ( 776) 760 145.6 1e-33
NP_996783 (OMIM: 603183,604805) reticulon-2 isofor ( 472) 569 111.8 9.4e-24
NP_996784 (OMIM: 603183,604805) reticulon-2 isofor ( 205) 558 109.7 1.7e-23
NP_005610 (OMIM: 603183,604805) reticulon-2 isofor ( 545) 558 109.9 4.1e-23
NP_001252520 (OMIM: 604249) reticulon-3 isoform g ( 214) 435 88.0 6.3e-17
>>NP_958831 (OMIM: 604249) reticulon-3 isoform b [Homo s (1013 aa)
initn: 6495 init1: 6495 opt: 6495 Z-score: 6200.8 bits: 1158.9 E(88908): 0
Smith-Waterman score: 6495; 100.0% identity (100.0% similar) in 1013 aa overlap (1-1013:1-1013)
10 20 30 40 50 60
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAEGLSSLCSDEPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAEGLSSLCSDEPSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQIDKETKNPNGVSSREAKTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 VSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQIDKETKNPNGVSSREAKTAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 DADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 EFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 EFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 AALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 AALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 KTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 MQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 MQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 SDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 SDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 FNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKAISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 FNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKAISE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 KMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 KMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 QEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILERNVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 QEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILERNVKN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 GSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 GSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 FGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 FGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 ITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 ITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITL
910 920 930 940 950 960
970 980 990 1000 1010
pF1KE0 LILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 LILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
970 980 990 1000 1010
>>NP_001252518 (OMIM: 604249) reticulon-3 isoform e [Hom (1032 aa)
initn: 6180 init1: 6180 opt: 6189 Z-score: 5908.5 bits: 1104.8 E(88908): 0
Smith-Waterman score: 6447; 98.2% identity (98.2% similar) in 1032 aa overlap (1-1013:1-1032)
10 20 30 40
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA-------------
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ------EGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE0 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE0 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE0 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE0 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE0 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE0 DFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE0 QAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKL
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE0 AVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQ
970 980 990 1000 1010 1020
1010
pF1KE0 AKLPGIAKKKAE
::::::::::::
NP_001 AKLPGIAKKKAE
1030
>>XP_011543032 (OMIM: 604249) PREDICTED: reticulon-3 iso (1037 aa)
initn: 5969 init1: 5969 opt: 5978 Z-score: 5707.0 bits: 1067.6 E(88908): 0
Smith-Waterman score: 6236; 98.1% identity (98.1% similar) in 998 aa overlap (1-979:1-998)
10 20 30 40
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ------EGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE0 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE0 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE0 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE0 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE0 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE0 DFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE0 QAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKL
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE0 AVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQ
::::::::::::::::::::::::::::::::::::::
XP_011 AVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKDPSKTPWNRQKKGRISTWKPEM
970 980 990 1000 1010 1020
1010
pF1KE0 AKLPGIAKKKAE
XP_011 QQLLKHHLIVITSLLVL
1030
>>NP_001252519 (OMIM: 604249) reticulon-3 isoform f [Hom (920 aa)
initn: 5573 init1: 5573 opt: 5577 Z-score: 5324.9 bits: 996.7 E(88908): 0
Smith-Waterman score: 5695; 90.8% identity (90.8% similar) in 1013 aa overlap (1-1013:1-920)
10 20 30 40 50 60
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAEGLSSLCSDEPSS
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA-------------
10 20 30 40
70 80 90 100 110 120
pF1KE0 EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNN
NP_001 ------------------------------------------------------------
130 140 150 160 170 180
pF1KE0 VSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQIDKETKNPNGVSSREAKTAL
::::::::::::::::::::::::::::::::::::::::
NP_001 --------------------ASFPEHPAFLSKKIGQVEEQIDKETKNPNGVSSREAKTAL
50 60 70 80
190 200 210 220 230 240
pF1KE0 DADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDK
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE0 EFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTN
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE0 AALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNL
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE0 KTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGN
270 280 290 300 310 320
430 440 450 460 470 480
pF1KE0 MQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGE
330 340 350 360 370 380
490 500 510 520 530 540
pF1KE0 SDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELV
390 400 410 420 430 440
550 560 570 580 590 600
pF1KE0 SDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNV
450 460 470 480 490 500
610 620 630 640 650 660
pF1KE0 FNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKAISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKAISE
510 520 530 540 550 560
670 680 690 700 710 720
pF1KE0 KMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLE
570 580 590 600 610 620
730 740 750 760 770 780
pF1KE0 QEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILERNVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILERNVKN
630 640 650 660 670 680
790 800 810 820 830 840
pF1KE0 GSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFV
690 700 710 720 730 740
850 860 870 880 890 900
pF1KE0 FGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVD
750 760 770 780 790 800
910 920 930 940 950 960
pF1KE0 ITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITL
810 820 830 840 850 860
970 980 990 1000 1010
pF1KE0 LILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
870 880 890 900 910 920
>>XP_016872580 (OMIM: 604249) PREDICTED: reticulon-3 iso (880 aa)
initn: 5414 init1: 5008 opt: 5022 Z-score: 4795.3 bits: 898.6 E(88908): 0
Smith-Waterman score: 5280; 97.4% identity (97.5% similar) in 847 aa overlap (1-828:1-847)
10 20 30 40
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ------EGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE0 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE0 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE0 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE0 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE0 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE0 DFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
::: .:
XP_016 DFSESSLGSHFVPHPVSLLSFNLRIKIKRSKFLSLSLSHH
850 860 870 880
>>XP_016872581 (OMIM: 604249) PREDICTED: reticulon-3 iso (848 aa)
initn: 5012 init1: 5012 opt: 5021 Z-score: 4794.6 bits: 898.4 E(88908): 0
Smith-Waterman score: 5279; 97.7% identity (97.7% similar) in 843 aa overlap (1-824:1-843)
10 20 30 40
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ------EGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCIT
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE0 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE0 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTE
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE0 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE0 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTF
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE0 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLT
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE0 DFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
:::
XP_016 DFSGFYWT
>>NP_958832 (OMIM: 604249) reticulon-3 isoform c [Homo s (255 aa)
initn: 1172 init1: 1172 opt: 1172 Z-score: 1127.7 bits: 218.2 E(88908): 4.7e-56
Smith-Waterman score: 1172; 97.4% identity (99.0% similar) in 195 aa overlap (819-1013:61-255)
790 800 810 820 830 840
pF1KE0 KPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIML
:.. .::::::::::::::::::::::::
NP_958 PGACPALGTKSCSSSCADSFVSSSSSQPVSLFSTSQVHDLIFWRDVKKTGFVFGTTLIML
40 50 60 70 80 90
850 860 870 880 890 900
pF1KE0 LSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 LSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAF
100 110 120 130 140 150
910 920 930 940 950 960
pF1KE0 HNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 HNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLI
160 170 180 190 200 210
970 980 990 1000 1010
pF1KE0 FSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
:::::::::::::::::::::::::::::::::::::::::::::
NP_958 FSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
220 230 240 250
>--
initn: 375 init1: 342 opt: 342 Z-score: 335.2 bits: 71.6 E(88908): 6.5e-12
Smith-Waterman score: 342; 85.0% identity (93.3% similar) in 60 aa overlap (1-60:1-60)
10 20 30 40 50 60
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAEGLSSLCSDEPSS
:::::::::::::::::::::::::::::::::::::::::::::::... : :..: :
NP_958 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNN
NP_958 LFSTSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYK
70 80 90 100 110 120
>>NP_006045 (OMIM: 604249) reticulon-3 isoform a [Homo s (236 aa)
initn: 1169 init1: 1169 opt: 1169 Z-score: 1125.4 bits: 217.7 E(88908): 6.3e-56
Smith-Waterman score: 1169; 99.5% identity (100.0% similar) in 190 aa overlap (824-1013:47-236)
800 810 820 830 840 850
pF1KE0 RETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAA
.:::::::::::::::::::::::::::::
NP_006 SFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAA
20 30 40 50 60 70
860 870 880 890 900 910
pF1KE0 FSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMN
80 90 100 110 120 130
920 930 940 950 960 970
pF1KE0 AAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPI
140 150 160 170 180 190
980 990 1000 1010
pF1KE0 VYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
::::::::::::::::::::::::::::::::::::::::
NP_006 VYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
200 210 220 230
>--
initn: 315 init1: 315 opt: 315 Z-score: 310.0 bits: 66.8 E(88908): 1.6e-10
Smith-Waterman score: 315; 100.0% identity (100.0% similar) in 46 aa overlap (1-46:1-46)
10 20 30 40 50 60
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAEGLSSLCSDEPSS
::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNN
NP_006 GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL
70 80 90 100 110 120
>>XP_011543033 (OMIM: 604249) PREDICTED: reticulon-3 iso (260 aa)
initn: 961 init1: 961 opt: 961 Z-score: 926.1 bits: 181.0 E(88908): 7.9e-45
Smith-Waterman score: 961; 96.9% identity (98.8% similar) in 161 aa overlap (819-979:61-221)
790 800 810 820 830 840
pF1KE0 KPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIML
:.. .::::::::::::::::::::::::
XP_011 PGACPALGTKSCSSSCADSFVSSSSSQPVSLFSTSQVHDLIFWRDVKKTGFVFGTTLIML
40 50 60 70 80 90
850 860 870 880 890 900
pF1KE0 LSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAF
100 110 120 130 140 150
910 920 930 940 950 960
pF1KE0 HNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLI
160 170 180 190 200 210
970 980 990 1000 1010
pF1KE0 FSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
:::::::::::
XP_011 FSVPIVYEKYKDPSKTPWNRQKKGRISTWKPEMQQLLKHHLIVITSLLVL
220 230 240 250 260
>--
initn: 375 init1: 342 opt: 342 Z-score: 335.1 bits: 71.6 E(88908): 6.6e-12
Smith-Waterman score: 342; 85.0% identity (93.3% similar) in 60 aa overlap (1-60:1-60)
10 20 30 40 50 60
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAEGLSSLCSDEPSS
:::::::::::::::::::::::::::::::::::::::::::::::... : :..: :
XP_011 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNN
XP_011 LFSTSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYK
70 80 90 100 110 120
>>NP_958833 (OMIM: 604249) reticulon-3 isoform d [Homo s (241 aa)
initn: 958 init1: 958 opt: 958 Z-score: 923.8 bits: 180.4 E(88908): 1.1e-44
Smith-Waterman score: 958; 99.4% identity (100.0% similar) in 156 aa overlap (824-979:47-202)
800 810 820 830 840 850
pF1KE0 RETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAA
.:::::::::::::::::::::::::::::
NP_958 SFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAA
20 30 40 50 60 70
860 870 880 890 900 910
pF1KE0 FSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 FSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMN
80 90 100 110 120 130
920 930 940 950 960 970
pF1KE0 AAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_958 AAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPI
140 150 160 170 180 190
980 990 1000 1010
pF1KE0 VYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
::::::
NP_958 VYEKYKDPSKTPWNRQKKGRISTWKPEMQQLLKHHLIVITSLLVL
200 210 220 230 240
>--
initn: 315 init1: 315 opt: 315 Z-score: 309.8 bits: 66.8 E(88908): 1.7e-10
Smith-Waterman score: 315; 100.0% identity (100.0% similar) in 46 aa overlap (1-46:1-46)
10 20 30 40 50 60
pF1KE0 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAEGLSSLCSDEPSS
::::::::::::::::::::::::::::::::::::::::::::::
NP_958 MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNN
NP_958 GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL
70 80 90 100 110 120
1013 residues in 1 query sequences
63214209 residues in 88908 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Sep 11 11:59:58 2017 done: Mon Sep 11 12:00:00 2017
Total Scan time: 12.140 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]