Result of FASTA (omim) for
pF1KE0030
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0030, 552 aa
1>>>pF1KE0030 552 - 552 aa - 552 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8660+/-0.000433; mu= 15.3028+/- 0.027
mean_var=67.6806+/-13.863, 0's: 0 Z-trim(110.2): 34 B-trim: 46 in 1/53
Lambda= 0.155899
statistics sampled from 18479 (18497) to 18479 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.579), E-opt: 0.2 (0.217), width: 16
Scan time: 10.100
The best scores are: opt bits E(85289)
NP_064555 (OMIM: 609156) nicalin isoform 1 precurs ( 563) 3562 810.6 0
NP_001308392 (OMIM: 609156) nicalin isoform 2 prec ( 562) 3543 806.4 0
NP_001300895 (OMIM: 190010,616740) transferrin rec ( 478) 166 46.8 0.00018
NP_001300894 (OMIM: 190010,616740) transferrin rec ( 679) 166 46.8 0.00025
NP_003225 (OMIM: 190010,616740) transferrin recept ( 760) 166 46.9 0.00028
NP_001121620 (OMIM: 190010,616740) transferrin rec ( 760) 166 46.9 0.00028
NP_001193784 (OMIM: 604250,604720) transferrin rec ( 630) 152 43.7 0.0021
XP_016868062 (OMIM: 604250,604720) PREDICTED: tran ( 801) 152 43.7 0.0026
XP_005250610 (OMIM: 604250,604720) PREDICTED: tran ( 801) 152 43.7 0.0026
NP_003218 (OMIM: 604250,604720) transferrin recept ( 801) 152 43.7 0.0026
>>NP_064555 (OMIM: 609156) nicalin isoform 1 precursor [ (563 aa)
initn: 3562 init1: 3562 opt: 3562 Z-score: 4327.9 bits: 810.6 E(85289): 0
Smith-Waterman score: 3562; 100.0% identity (100.0% similar) in 552 aa overlap (1-552:12-563)
10 20 30 40
pF1KE0 MLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQP
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 YGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 YGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 QDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTAT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 ANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 NGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 NGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 LQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 INLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 INLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 ALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 HHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 HHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAY
490 500 510 520 530 540
530 540 550
pF1KE0 VAVQHFSLLYKTVQRLLVKAKTQ
:::::::::::::::::::::::
NP_064 VAVQHFSLLYKTVQRLLVKAKTQ
550 560
>>NP_001308392 (OMIM: 609156) nicalin isoform 2 precurso (562 aa)
initn: 2804 init1: 2804 opt: 3543 Z-score: 4304.8 bits: 806.4 E(85289): 0
Smith-Waterman score: 3543; 99.8% identity (99.8% similar) in 552 aa overlap (1-552:12-562)
10 20 30 40
pF1KE0 MLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQP
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 YGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 QDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTAT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 ANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 NGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 LQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 INLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 ALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLE
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_001 ALTRVIYNLTEKGTPPDMPVFTEQM-IQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLE
430 440 450 460 470
470 480 490 500 510 520
pF1KE0 HHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAY
480 490 500 510 520 530
530 540 550
pF1KE0 VAVQHFSLLYKTVQRLLVKAKTQ
:::::::::::::::::::::::
NP_001 VAVQHFSLLYKTVQRLLVKAKTQ
540 550 560
>>NP_001300895 (OMIM: 190010,616740) transferrin recepto (478 aa)
initn: 133 init1: 109 opt: 166 Z-score: 201.1 bits: 46.8 E(85289): 0.00018
Smith-Waterman score: 170; 24.4% identity (54.2% similar) in 275 aa overlap (182-454:96-348)
160 170 180 190 200 210
pF1KE0 SASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIV
:..... : .. : . :. : .:.
NP_001 NMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKGFVEPD-HYVVVG
70 80 90 100 110 120
220 230 240 250 260 270
pF1KE0 AHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNY
:. ::.: : :: ..: :...::.::..:: . . . ...: . ..: :.
NP_001 AQRDAWG--P----GAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGS
130 140 150 160 170
280 290 300 310 320 330
pF1KE0 QGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELE
:. .::: : ::: ... :: . :.: ...:: : :: . .....
NP_001 VGATEWLEGYL----SSLHLKAFTYI-NLDKAVLGTS-NFKVSASPLLYTLIEKTMQNVK
180 190 200 210 220 230
340 350 360 370 380 390
pF1KE0 TVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDV
.. :: . . : .:. : :. .: .:: .. :. .. ::.
NP_001 HPVTGQFLYQDSNWASKVEKLTLDNAAFPF--LAYSGIPAVSFCFCEDTDYPYLGTTMDT
240 250 260 270 280 290
400 410 420 430 440
pF1KE0 RSRVDSKT--LTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLT
... . :.. .: ::. . . .::. :. . . . ... :. : :
NP_001 YKELIERIPELNKVARAAAEVAGQFVIKLTH-----DVELNLDYERYNSQLLSFVRD--L
300 310 320 330 340
450 460 470 480 490 500
pF1KE0 NQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVK
:: ::
NP_001 NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHF
350 360 370 380 390 400
>>NP_001300894 (OMIM: 190010,616740) transferrin recepto (679 aa)
initn: 109 init1: 109 opt: 166 Z-score: 198.6 bits: 46.8 E(85289): 0.00025
Smith-Waterman score: 170; 24.4% identity (54.2% similar) in 275 aa overlap (182-454:297-549)
160 170 180 190 200 210
pF1KE0 SASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIV
:..... : .. : . :. : .:.
NP_001 NMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKGFVEPD-HYVVVG
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE0 AHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNY
:. ::.: : :: ..: :...::.::..:: . . . ...: . ..: :.
NP_001 AQRDAWG--P----GAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGS
330 340 350 360 370
280 290 300 310 320 330
pF1KE0 QGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELE
:. .::: : ::: ... :: . :.: ...:: : :: . .....
NP_001 VGATEWLEGYL----SSLHLKAFTYI-NLDKAVLGTS-NFKVSASPLLYTLIEKTMQNVK
380 390 400 410 420 430
340 350 360 370 380 390
pF1KE0 TVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDV
.. :: . . : .:. : :. .: .:: .. :. .. ::.
NP_001 HPVTGQFLYQDSNWASKVEKLTLDNAAFPF--LAYSGIPAVSFCFCEDTDYPYLGTTMDT
440 450 460 470 480 490
400 410 420 430 440
pF1KE0 RSRVDSKT--LTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLT
... . :.. .: ::. . . .::. :. . . . ... :. : :
NP_001 YKELIERIPELNKVARAAAEVAGQFVIKLTH-----DVELNLDYERYNSQLLSFVRD--L
500 510 520 530 540
450 460 470 480 490 500
pF1KE0 NQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVK
:: ::
NP_001 NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHF
550 560 570 580 590 600
>>NP_003225 (OMIM: 190010,616740) transferrin receptor p (760 aa)
initn: 109 init1: 109 opt: 166 Z-score: 197.8 bits: 46.9 E(85289): 0.00028
Smith-Waterman score: 170; 24.4% identity (54.2% similar) in 275 aa overlap (182-454:378-630)
160 170 180 190 200 210
pF1KE0 SASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIV
:..... : .. : . :. : .:.
NP_003 NMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKGFVEPD-HYVVVG
350 360 370 380 390 400
220 230 240 250 260 270
pF1KE0 AHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNY
:. ::.: : :: ..: :...::.::..:: . . . ...: . ..: :.
NP_003 AQRDAWG--P----GAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGS
410 420 430 440 450 460
280 290 300 310 320 330
pF1KE0 QGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELE
:. .::: : ::: ... :: . :.: ...:: : :: . .....
NP_003 VGATEWLEGYL----SSLHLKAFTYI-NLDKAVLGTS-NFKVSASPLLYTLIEKTMQNVK
470 480 490 500 510
340 350 360 370 380 390
pF1KE0 TVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDV
.. :: . . : .:. : :. .: .:: .. :. .. ::.
NP_003 HPVTGQFLYQDSNWASKVEKLTLDNAAFPF--LAYSGIPAVSFCFCEDTDYPYLGTTMDT
520 530 540 550 560 570
400 410 420 430 440
pF1KE0 RSRVDSKT--LTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLT
... . :.. .: ::. . . .::. :. . . . ... :. : :
NP_003 YKELIERIPELNKVARAAAEVAGQFVIKLTH-----DVELNLDYERYNSQLLSFVRD--L
580 590 600 610 620
450 460 470 480 490 500
pF1KE0 NQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVK
:: ::
NP_003 NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHF
630 640 650 660 670 680
>>NP_001121620 (OMIM: 190010,616740) transferrin recepto (760 aa)
initn: 109 init1: 109 opt: 166 Z-score: 197.8 bits: 46.9 E(85289): 0.00028
Smith-Waterman score: 170; 24.4% identity (54.2% similar) in 275 aa overlap (182-454:378-630)
160 170 180 190 200 210
pF1KE0 SASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIV
:..... : .. : . :. : .:.
NP_001 NMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKGFVEPD-HYVVVG
350 360 370 380 390 400
220 230 240 250 260 270
pF1KE0 AHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNY
:. ::.: : :: ..: :...::.::..:: . . . ...: . ..: :.
NP_001 AQRDAWG--P----GAAKSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGS
410 420 430 440 450 460
280 290 300 310 320 330
pF1KE0 QGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELE
:. .::: : ::: ... :: . :.: ...:: : :: . .....
NP_001 VGATEWLEGYL----SSLHLKAFTYI-NLDKAVLGTS-NFKVSASPLLYTLIEKTMQNVK
470 480 490 500 510
340 350 360 370 380 390
pF1KE0 TVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDV
.. :: . . : .:. : :. .: .:: .. :. .. ::.
NP_001 HPVTGQFLYQDSNWASKVEKLTLDNAAFPF--LAYSGIPAVSFCFCEDTDYPYLGTTMDT
520 530 540 550 560 570
400 410 420 430 440
pF1KE0 RSRVDSKT--LTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLT
... . :.. .: ::. . . .::. :. . . . ... :. : :
NP_001 YKELIERIPELNKVARAAAEVAGQFVIKLTH-----DVELNLDYERYNSQLLSFVRD--L
580 590 600 610 620
450 460 470 480 490 500
pF1KE0 NQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVK
:: ::
NP_001 NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHF
630 640 650 660 670 680
>>NP_001193784 (OMIM: 604250,604720) transferrin recepto (630 aa)
initn: 121 init1: 69 opt: 152 Z-score: 182.1 bits: 43.7 E(85289): 0.0021
Smith-Waterman score: 161; 24.2% identity (55.9% similar) in 256 aa overlap (115-370:171-395)
90 100 110 120 130 140
pF1KE0 QYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSI
:: . : : :. . .. ::
NP_001 SLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASR-LLRK
150 160 170 180 190
150 160 170 180 190 200
pF1KE0 YKQTQAASASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGED
: : . ::: .. : . . ...:... .... . ... .::: .:
NP_001 LKGPVAPQEWQGSLLGSPYHL--GPGPRLRLVVNNHRTSTPINNIFGCIEGR-----SEP
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE0 LPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFAS
.:: :. ::.: : :: ... :...::::.: :: . . . . .:::..
NP_001 DHYVVIGAQRDAWG--P----GAAKSAVGTAILLELVRTFSSMVS-NGFRPRRSLLFISW
260 270 280 290 300
270 280 290 300 310 320
pF1KE0 GGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQH
:: :. :. .::: : :.:. ... . ::.. :.. ..:.. : .: .
NP_001 DGGDFGSVGSTEWLEGYL-----SVLHLKAVVYVSLDNAVLGDD-KFHAKTSPLLTSLIE
310 320 330 340 350
330 340 350 360 370 380
pF1KE0 AFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQ
. :..... :. . ..... ... .:. : .:: ::
NP_001 SVLKQVDS------PNHSGQTLYEQVVFTNP--SWDAE--VIRPLPMDSSAYSFTAFVGV
360 370 380 390 400
390 400 410 420 430 440
pF1KE0 RSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSV
NP_001 PAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLP
410 420 430 440 450 460
>>XP_016868062 (OMIM: 604250,604720) PREDICTED: transfer (801 aa)
initn: 121 init1: 69 opt: 152 Z-score: 180.4 bits: 43.7 E(85289): 0.0026
Smith-Waterman score: 161; 24.2% identity (55.9% similar) in 256 aa overlap (115-370:342-566)
90 100 110 120 130 140
pF1KE0 QYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSI
:: . : : :. . .. ::
XP_016 SLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASR-LLRK
320 330 340 350 360 370
150 160 170 180 190 200
pF1KE0 YKQTQAASASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGED
: : . ::: .. : . . ...:... .... . ... .::: .:
XP_016 LKGPVAPQEWQGSLLGSPYHL--GPGPRLRLVVNNHRTSTPINNIFGCIEGR-----SEP
380 390 400 410 420
210 220 230 240 250 260
pF1KE0 LPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFAS
.:: :. ::.: : :: ... :...::::.: :: . . . . .:::..
XP_016 DHYVVIGAQRDAWG--P----GAAKSAVGTAILLELVRTFSSMVS-NGFRPRRSLLFISW
430 440 450 460 470
270 280 290 300 310 320
pF1KE0 GGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQH
:: :. :. .::: : :.:. ... . ::.. :.. ..:.. : .: .
XP_016 DGGDFGSVGSTEWLEGYL-----SVLHLKAVVYVSLDNAVLGDD-KFHAKTSPLLTSLIE
480 490 500 510 520 530
330 340 350 360 370 380
pF1KE0 AFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQ
. :..... :. . ..... ... .:. : .:: ::
XP_016 SVLKQVDS------PNHSGQTLYEQVVFTNP--SWDAE--VIRPLPMDSSAYSFTAFVGV
540 550 560 570 580
390 400 410 420 430 440
pF1KE0 RSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSV
XP_016 PAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLP
590 600 610 620 630 640
>>XP_005250610 (OMIM: 604250,604720) PREDICTED: transfer (801 aa)
initn: 121 init1: 69 opt: 152 Z-score: 180.4 bits: 43.7 E(85289): 0.0026
Smith-Waterman score: 161; 24.2% identity (55.9% similar) in 256 aa overlap (115-370:342-566)
90 100 110 120 130 140
pF1KE0 QYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSI
:: . : : :. . .. ::
XP_005 SLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASR-LLRK
320 330 340 350 360 370
150 160 170 180 190 200
pF1KE0 YKQTQAASASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGED
: : . ::: .. : . . ...:... .... . ... .::: .:
XP_005 LKGPVAPQEWQGSLLGSPYHL--GPGPRLRLVVNNHRTSTPINNIFGCIEGR-----SEP
380 390 400 410 420
210 220 230 240 250 260
pF1KE0 LPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFAS
.:: :. ::.: : :: ... :...::::.: :: . . . . .:::..
XP_005 DHYVVIGAQRDAWG--P----GAAKSAVGTAILLELVRTFSSMVS-NGFRPRRSLLFISW
430 440 450 460 470
270 280 290 300 310 320
pF1KE0 GGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQH
:: :. :. .::: : :.:. ... . ::.. :.. ..:.. : .: .
XP_005 DGGDFGSVGSTEWLEGYL-----SVLHLKAVVYVSLDNAVLGDD-KFHAKTSPLLTSLIE
480 490 500 510 520 530
330 340 350 360 370 380
pF1KE0 AFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQ
. :..... :. . ..... ... .:. : .:: ::
XP_005 SVLKQVDS------PNHSGQTLYEQVVFTNP--SWDAE--VIRPLPMDSSAYSFTAFVGV
540 550 560 570 580
390 400 410 420 430 440
pF1KE0 RSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSV
XP_005 PAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLP
590 600 610 620 630 640
>>NP_003218 (OMIM: 604250,604720) transferrin receptor p (801 aa)
initn: 121 init1: 69 opt: 152 Z-score: 180.4 bits: 43.7 E(85289): 0.0026
Smith-Waterman score: 161; 24.2% identity (55.9% similar) in 256 aa overlap (115-370:342-566)
90 100 110 120 130 140
pF1KE0 QYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSI
:: . : : :. . .. ::
NP_003 SLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASR-LLRK
320 330 340 350 360 370
150 160 170 180 190 200
pF1KE0 YKQTQAASASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGED
: : . ::: .. : . . ...:... .... . ... .::: .:
NP_003 LKGPVAPQEWQGSLLGSPYHL--GPGPRLRLVVNNHRTSTPINNIFGCIEGR-----SEP
380 390 400 410 420
210 220 230 240 250 260
pF1KE0 LPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFAS
.:: :. ::.: : :: ... :...::::.: :: . . . . .:::..
NP_003 DHYVVIGAQRDAWG--P----GAAKSAVGTAILLELVRTFSSMVS-NGFRPRRSLLFISW
430 440 450 460 470
270 280 290 300 310 320
pF1KE0 GGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQH
:: :. :. .::: : :.:. ... . ::.. :.. ..:.. : .: .
NP_003 DGGDFGSVGSTEWLEGYL-----SVLHLKAVVYVSLDNAVLGDD-KFHAKTSPLLTSLIE
480 490 500 510 520 530
330 340 350 360 370 380
pF1KE0 AFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQ
. :..... :. . ..... ... .:. : .:: ::
NP_003 SVLKQVDS------PNHSGQTLYEQVVFTNP--SWDAE--VIRPLPMDSSAYSFTAFVGV
540 550 560 570 580
390 400 410 420 430 440
pF1KE0 RSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSV
NP_003 PAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLP
590 600 610 620 630 640
552 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:28:15 2016 done: Fri Nov 4 07:28:16 2016
Total Scan time: 10.100 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]