FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0025, 574 aa
  1>>>pF1KE0025 574 - 574 aa - 574 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9996+/-0.000421; mu= 14.9253+/- 0.026
 mean_var=75.3734+/-15.185, 0's: 0 Z-trim(110.7): 26  B-trim: 132 in 1/55
 Lambda= 0.147729
 statistics sampled from 19104 (19121) to 19104 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.224), width:  16
 Scan time: 10.490

The best scores are:                                      opt bits E(85289)
NP_003120 (OMIM: 602019) squalene monooxygenase [H ( 574) 3741 807.3       0
XP_011515548 (OMIM: 602019) PREDICTED: squalene mo ( 516) 3104 671.5 1.8e-192


>>NP_003120 (OMIM: 602019) squalene monooxygenase [Homo   (574 aa)
 initn: 3741 init1: 3741 opt: 3741  Z-score: 4309.6  bits: 807.3 E(85289):    0
Smith-Waterman score: 3741; 99.1% identity (99.5% similar) in 574 aa overlap (1-574:1-574)

               10        20        30        40        50        60
pF1KE0 MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLFYRCRHRNGGLLGRQQSG
       :::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_003 MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SVSSHFVGFLMKNAPQFKANHAELILANPSPVLTYQISSSETRVLVDIRGEMPRNLREYM
       ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_003 SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 VEKIYPQIPDHLKEPSLEVADNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG
       ::::::::::::::: ::..::::::::::::::::::::::::::::::::::::::::
NP_003 VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW
              490       500       510       520       530       540

              550       560       570    
pF1KE0 ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
       ::::::::::::::::::::::::::::::::::
NP_003 ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
              550       560       570    

>>XP_011515548 (OMIM: 602019) PREDICTED: squalene monoox  (516 aa)
 initn: 3101 init1: 3101 opt: 3104  Z-score: 3576.6  bits: 671.5 E(85289): 1.8e-192
Smith-Waterman score: 3104; 97.9% identity (99.2% similar) in 485 aa overlap (90-574:32-516)

      60        70        80        90       100       110         
pF1KE0 GSQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTS
                                     .:. .. :::::::::::::::::::::::
XP_011 LEFHFEGEEQPLSMMKKFLKSSWVRIGFVPEEERNVLRRRKGTNISETSLIGTAACTSTS
              10        20        30        40        50        60 

     120       130       140       150       160       170         
pF1KE0 SQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLG
              70        80        90       100       110       120 

     180       190       200       210       220       230         
pF1KE0 LGDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMA
             130       140       150       160       170       180 

     240       250       260       270       280       290         
pF1KE0 EPNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNK
             190       200       210       220       230       240 

     300       310       320       330       340       350         
pF1KE0 VSVSSHFVGFLMKNAPQFKANHAELILANPSPVLTYQISSSETRVLVDIRGEMPRNLREY
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 VSVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREY
             250       260       270       280       290       300 

     360       370       380       390       400       410         
pF1KE0 MVEKIYPQIPDHLKEPSLEVADNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGG
       :::::::::::::::: ::..:::::::::::::::::::::::::::::::::::::::
XP_011 MVEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGG
             310       320       330       340       350       360 

     420       430       440       450       460       470         
pF1KE0 GMTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSA
             370       380       390       400       410       420 

     480       490       500       510       520       530         
pF1KE0 TDDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEP
             430       440       450       460       470       480 

     540       550       560       570    
pF1KE0 WITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
       :::::::::::::::::::::::::::::::::::
XP_011 WITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
             490       500       510      




574 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 08:14:41 2016 done: Fri Nov  4 08:14:43 2016
 Total Scan time: 10.490 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]