Result of FASTA (omim) for
pF1KB9698
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9698, 291 aa
1>>>pF1KB9698 291 - 291 aa - 291 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3128+/-0.000416; mu= 17.4657+/- 0.026
mean_var=115.0463+/-24.198, 0's: 0 Z-trim(114.2): 185 B-trim: 749 in 1/49
Lambda= 0.119574
statistics sampled from 23607 (23850) to 23607 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.28), width: 16
Scan time: 5.750
The best scores are: opt bits E(85289)
NP_000297 (OMIM: 173110,613038) pituitary-specific ( 291) 1927 343.3 3.4e-94
NP_001116229 (OMIM: 173110,613038) pituitary-speci ( 317) 1652 295.9 6.8e-80
NP_005595 (OMIM: 600494) POU domain, class 3, tran ( 443) 623 118.5 2.3e-26
NP_006227 (OMIM: 602480) POU domain, class 3, tran ( 500) 612 116.7 9.3e-26
NP_000298 (OMIM: 300039,304400) POU domain, class ( 361) 609 116.0 1.1e-25
NP_002690 (OMIM: 602479) POU domain, class 3, tran ( 451) 604 115.3 2.3e-25
XP_016872976 (OMIM: 607394) PREDICTED: POU domain, ( 356) 515 99.8 8.1e-21
XP_011541045 (OMIM: 607394) PREDICTED: POU domain, ( 403) 515 99.8 8.8e-21
XP_011541044 (OMIM: 607394) PREDICTED: POU domain, ( 403) 515 99.8 8.8e-21
XP_011541043 (OMIM: 607394) PREDICTED: POU domain, ( 403) 515 99.8 8.8e-21
XP_011541041 (OMIM: 607394) PREDICTED: POU domain, ( 432) 515 99.9 9.2e-21
XP_011541042 (OMIM: 607394) PREDICTED: POU domain, ( 432) 515 99.9 9.2e-21
NP_055167 (OMIM: 607394) POU domain, class 2, tran ( 436) 515 99.9 9.3e-21
NP_001231611 (OMIM: 607394) POU domain, class 2, t ( 438) 515 99.9 9.3e-21
NP_002692 (OMIM: 164177) POU domain, class 5, tran ( 360) 480 93.7 5.4e-19
NP_002691 (OMIM: 602459,602460) POU domain, class ( 338) 479 93.5 5.8e-19
NP_001272916 (OMIM: 164177) POU domain, class 5, t ( 265) 475 92.7 8.1e-19
NP_001159490 (OMIM: 601583,609062) POU domain, cla ( 655) 472 92.7 2e-18
NP_001153014 (OMIM: 615739) putative POU domain, c ( 359) 457 89.8 8.4e-18
NP_006228 (OMIM: 601632) POU domain, class 4, tran ( 419) 457 89.9 9.3e-18
NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 454 89.3 1.3e-17
NP_001167002 (OMIM: 164177) POU domain, class 5, t ( 190) 374 75.1 1.1e-13
NP_976034 (OMIM: 164177) POU domain, class 5, tran ( 190) 374 75.1 1.1e-13
NP_001193955 (OMIM: 164176) POU domain, class 2, t ( 467) 334 68.7 2.4e-11
NP_001193954 (OMIM: 164176) POU domain, class 2, t ( 479) 334 68.7 2.5e-11
XP_011525343 (OMIM: 164176) PREDICTED: POU domain, ( 501) 334 68.7 2.5e-11
XP_011525345 (OMIM: 164176) PREDICTED: POU domain, ( 537) 334 68.8 2.7e-11
XP_016882385 (OMIM: 164176) PREDICTED: POU domain, ( 600) 334 68.8 2.8e-11
XP_016882383 (OMIM: 164176) PREDICTED: POU domain, ( 602) 334 68.8 2.9e-11
XP_016882384 (OMIM: 164176) PREDICTED: POU domain, ( 602) 334 68.8 2.9e-11
XP_011525342 (OMIM: 164176) PREDICTED: POU domain, ( 624) 334 68.8 2.9e-11
XP_016882381 (OMIM: 164176) PREDICTED: POU domain, ( 701) 334 68.9 3.1e-11
XP_016882375 (OMIM: 164176) PREDICTED: POU domain, ( 711) 334 68.9 3.2e-11
XP_016882377 (OMIM: 164176) PREDICTED: POU domain, ( 711) 334 68.9 3.2e-11
XP_016882379 (OMIM: 164176) PREDICTED: POU domain, ( 711) 334 68.9 3.2e-11
XP_016882378 (OMIM: 164176) PREDICTED: POU domain, ( 711) 334 68.9 3.2e-11
XP_016882376 (OMIM: 164176) PREDICTED: POU domain, ( 711) 334 68.9 3.2e-11
XP_016882373 (OMIM: 164176) PREDICTED: POU domain, ( 723) 334 68.9 3.2e-11
XP_016882374 (OMIM: 164176) PREDICTED: POU domain, ( 723) 334 68.9 3.2e-11
NP_001234923 (OMIM: 164176) POU domain, class 2, t ( 400) 311 64.6 3.4e-10
NP_002689 (OMIM: 164176) POU domain, class 2, tran ( 463) 311 64.7 3.8e-10
XP_011525344 (OMIM: 164176) PREDICTED: POU domain, ( 485) 311 64.7 3.9e-10
XP_005259067 (OMIM: 164176) PREDICTED: POU domain, ( 586) 311 64.8 4.4e-10
XP_016882382 (OMIM: 164176) PREDICTED: POU domain, ( 608) 311 64.9 4.5e-10
XP_016882380 (OMIM: 164176) PREDICTED: POU domain, ( 707) 311 64.9 4.9e-10
XP_016856997 (OMIM: 164175) PREDICTED: POU domain, ( 381) 306 63.8 6.1e-10
XP_011507957 (OMIM: 164175) PREDICTED: POU domain, ( 671) 308 64.4 6.8e-10
NP_001185715 (OMIM: 164175) POU domain, class 2, t ( 703) 308 64.4 7e-10
XP_011507956 (OMIM: 164175) PREDICTED: POU domain, ( 743) 308 64.5 7.3e-10
NP_001185712 (OMIM: 164175) POU domain, class 2, t ( 755) 308 64.5 7.4e-10
>>NP_000297 (OMIM: 173110,613038) pituitary-specific pos (291 aa)
initn: 1927 init1: 1927 opt: 1927 Z-score: 1812.1 bits: 343.3 E(85289): 3.4e-94
Smith-Waterman score: 1927; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHYSVPSCHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHYSVPSCHY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPS
190 200 210 220 230 240
250 260 270 280 290
pF1KB9 SQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
250 260 270 280 290
>>NP_001116229 (OMIM: 173110,613038) pituitary-specific (317 aa)
initn: 1637 init1: 1637 opt: 1652 Z-score: 1555.3 bits: 295.9 E(85289): 6.8e-80
Smith-Waterman score: 1865; 91.8% identity (91.8% similar) in 317 aa overlap (1-291:1-317)
10 20 30 40
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMST-------------
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTVPSILSLIQTPKC
10 20 30 40 50 60
50 60 70 80 90
pF1KB9 -------------ATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCTHFSVTTLGNTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT
250 260 270 280 290 300
280 290
pF1KB9 SLNQSLFSISKEHLECR
:::::::::::::::::
NP_001 SLNQSLFSISKEHLECR
310
>>NP_005595 (OMIM: 600494) POU domain, class 3, transcri (443 aa)
initn: 602 init1: 326 opt: 623 Z-score: 594.3 bits: 118.5 E(85289): 2.3e-26
Smith-Waterman score: 623; 47.0% identity (67.1% similar) in 249 aa overlap (30-272:172-412)
10 20 30 40 50
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHYSVPSCH
.:: :: : :.: :: :: ::
NP_005 QQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASN-----GGLLYSQPSFT
150 160 170 180 190
60 70 80 90 100 110
pF1KB9 YGNQPSTYGVMAGSLTPCL---YKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSK
... .. : :: : . : :. : : : : ..: : .
NP_005 VNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSH-P--HQQPPPPPPPQGPPGHPG
200 210 220 230 240 250
120 130 140 150 160 170
pF1KB9 LVEEP-IDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFEN
..: : :.: .::.::..:: ::::::.::..:: ::....:. ::::::::::
NP_005 AHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEA
260 270 280 290 300 310
180 190 200 210 220 230
pF1KB9 LQLSFKNACKLKAILSKWLEEAEQVGALYN--EKVGANERKRKRRTTISIAAKDALERHF
::::::: :::: .:.::::::.. .. . .:..:. ::::.::.: ...: ::: ::
NP_005 LQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHF
320 330 340 350 360 370
240 250 260 270 280 290
pF1KB9 GEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
. :::.::: .:. :.:::::::::::::::.:::.
NP_005 LKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTP
380 390 400 410 420 430
NP_005 PHHGVQTPVQ
440
>>NP_006227 (OMIM: 602480) POU domain, class 3, transcri (500 aa)
initn: 597 init1: 324 opt: 612 Z-score: 583.4 bits: 116.7 E(85289): 9.3e-26
Smith-Waterman score: 612; 50.0% identity (72.1% similar) in 208 aa overlap (68-272:258-464)
40 50 60 70 80 90
pF1KB9 SNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPL
:.. :. :: : . : :. : .:
NP_006 FTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGD-TPELAEHHHHHHHHAHPHPPHPH
230 240 250 260 270 280
100 110 120 130 140 150
pF1KB9 LAEDPTAADFKQELRRKSKLVEEP-IDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEA
:. : . ..: : :.: .::.::..:: ::::::.::..:: :
NP_006 HAQGPPHHGGGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLA
290 300 310 320 330 340
160 170 180 190 200 210
pF1KB9 LAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQ-VGALYN-EKVGANERK
:....:. :::::::::: ::::::: :::: .:.::::::.. .:. . .:..:. ::
NP_006 LGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRK
350 360 370 380 390 400
220 230 240 250 260 270
pF1KB9 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT
::.::.: ...: ::: :: . :::.::: .:. :.:::::::::::::::.:::.
NP_006 RKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTP
410 420 430 440 450 460
280 290
pF1KB9 SLNQSLFSISKEHLECR
NP_006 PGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ
470 480 490 500
>>NP_000298 (OMIM: 300039,304400) POU domain, class 3, t (361 aa)
initn: 586 init1: 344 opt: 609 Z-score: 582.3 bits: 116.0 E(85289): 1.1e-25
Smith-Waterman score: 614; 43.9% identity (68.2% similar) in 264 aa overlap (24-278:99-342)
10 20 30 40 50
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHY
: . ::: : .:: :. ... . .
NP_000 STLATSPLDQQDVKPGREDLQLGAIIHHRSPHVAHHS-----PHTNHP-NAWGASPAPNP
70 80 90 100 110 120
60 70 80 90 100
pF1KB9 SVPSC----HYGNQP--STYGVMA-GSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAAD
:. : . .:: .. :.. :.::: : . : .: :.: : : ..
NP_000 SITSSGQPLNVYSQPGFTVSGMLEHGGLTP-----PPAAASA--QSLH-PVLREPPDHGE
130 140 150 160 170
110 120 130 140 150 160
pF1KB9 FKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFS
. :. .. : ..: :::.::..:: ::::::.::..:: ::....:. ::
NP_000 LG------SHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFS
180 190 200 210 220
170 180 190 200 210 220
pF1KB9 QTTICRFENLQLSFKNACKLKAILSKWLEEAEQ-VGALYN-EKVGANERKRKRRTTISIA
:::::::: ::::::: :::: .:.::::::.. .:. . .:..:. ::::.::.: ..
NP_000 QTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVS
230 240 250 260 270 280
230 240 250 260 270 280
pF1KB9 AKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSIS
.: .:: :: . ::..::: .:. :.:::::::::::::::.:::. .:
NP_000 VKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEVY
290 300 310 320 330 340
290
pF1KB9 KEHLECR
NP_000 SHTVKTDTSCHDL
350 360
>>NP_002690 (OMIM: 602479) POU domain, class 3, transcri (451 aa)
initn: 587 init1: 344 opt: 604 Z-score: 576.5 bits: 115.3 E(85289): 2.3e-25
Smith-Waterman score: 604; 51.8% identity (74.1% similar) in 193 aa overlap (82-272:205-397)
60 70 80 90 100 110
pF1KB9 HYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQEL
: : .:: : . .:: ..
NP_002 MLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGA
180 190 200 210 220 230
120 130 140 150 160 170
pF1KB9 RRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTIC
.. : : : :.: .::.::..:: ::::::.::..:: ::....:. :::::::
NP_002 GGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTIC
240 250 260 270 280 290
180 190 200 210 220
pF1KB9 RFENLQLSFKNACKLKAILSKWLEEAEQV-GALYN-EKVGANERKRKRRTTISIAAKDAL
::: ::::::: :::: .:.:::::... :. : .:..:. ::::.::.: ...: ::
NP_002 RFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGAL
300 310 320 330 340 350
230 240 250 260 270 280
pF1KB9 ERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLE
: :: . :::..:: .:. :.:::::::::::::::.:::.
NP_002 ESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAP
360 370 380 390 400 410
290
pF1KB9 CR
NP_002 GELGPGGGGASPPSAPPPPPPAALHHHHHHTLPGSVQ
420 430 440 450
>>XP_016872976 (OMIM: 607394) PREDICTED: POU domain, cla (356 aa)
initn: 536 init1: 298 opt: 515 Z-score: 494.7 bits: 99.8 E(85289): 8.1e-21
Smith-Waterman score: 516; 40.0% identity (64.9% similar) in 265 aa overlap (30-272:81-339)
10 20 30 40 50
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSN-HATNVMSTATGLHYSVPSC
.:. : ... : . . . : :: .
XP_016 SDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQF
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB9 HYGN-QPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAED----P--TAADFKQEL
.. ::. : : : : ::.. : . : : :: . : ..... .:
XP_016 LLSQTQPGQQG-----LQPNLLPFPQQQ-SGLLLPQTGPGLASQAFGHPGLPGSSLEPHL
120 130 140 150 160
120 130 140 150 160
pF1KB9 RRKSKL-VEEPID----MDSP-EIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEF
. ...: : . . : : ...::::::. :: ::::::.:: .:: :.. ..:..:
XP_016 EASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDF
170 180 190 200 210 220
170 180 190 200 210
pF1KB9 SQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANE--------RKRKR
::::: ::: :.::::: :::: .: :::..::. . . .. .. ::::.
XP_016 SQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKK
230 240 250 260 270 280
220 230 240 250 260 270
pF1KB9 RTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLN
::.: . .::..: .. ::::.:: .::.:..::::::::::::::.:::.
XP_016 RTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVA
290 300 310 320 330 340
280 290
pF1KB9 QSLFSISKEHLECR
XP_016 TPIKPPVYNSRL
350
>>XP_011541045 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 536 init1: 298 opt: 515 Z-score: 494.1 bits: 99.8 E(85289): 8.8e-21
Smith-Waterman score: 516; 40.0% identity (64.9% similar) in 265 aa overlap (30-272:48-306)
10 20 30 40 50
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSN-HATNVMSTATGLHYSVPSC
.:. : ... : . . . : :: .
XP_011 SDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQF
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB9 HYGN-QPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAED----P--TAADFKQEL
.. ::. : : : : ::.. : . : : :: . : ..... .:
XP_011 LLSQTQPGQQG-----LQPNLLPFPQQQ-SGLLLPQTGPGLASQAFGHPGLPGSSLEPHL
80 90 100 110 120 130
120 130 140 150 160
pF1KB9 RRKSKL-VEEPID----MDSP-EIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEF
. ...: : . . : : ...::::::. :: ::::::.:: .:: :.. ..:..:
XP_011 EASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDF
140 150 160 170 180 190
170 180 190 200 210
pF1KB9 SQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANE--------RKRKR
::::: ::: :.::::: :::: .: :::..::. . . .. .. ::::.
XP_011 SQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKK
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB9 RTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLN
::.: . .::..: .. ::::.:: .::.:..::::::::::::::.:::.
XP_011 RTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVA
260 270 280 290 300 310
280 290
pF1KB9 QSLFSISKEHLECR
XP_011 TPIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPT
320 330 340 350 360 370
>>XP_011541044 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 536 init1: 298 opt: 515 Z-score: 494.1 bits: 99.8 E(85289): 8.8e-21
Smith-Waterman score: 516; 40.0% identity (64.9% similar) in 265 aa overlap (30-272:48-306)
10 20 30 40 50
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSN-HATNVMSTATGLHYSVPSC
.:. : ... : . . . : :: .
XP_011 SDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQF
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB9 HYGN-QPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAED----P--TAADFKQEL
.. ::. : : : : ::.. : . : : :: . : ..... .:
XP_011 LLSQTQPGQQG-----LQPNLLPFPQQQ-SGLLLPQTGPGLASQAFGHPGLPGSSLEPHL
80 90 100 110 120 130
120 130 140 150 160
pF1KB9 RRKSKL-VEEPID----MDSP-EIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEF
. ...: : . . : : ...::::::. :: ::::::.:: .:: :.. ..:..:
XP_011 EASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDF
140 150 160 170 180 190
170 180 190 200 210
pF1KB9 SQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANE--------RKRKR
::::: ::: :.::::: :::: .: :::..::. . . .. .. ::::.
XP_011 SQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKK
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB9 RTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLN
::.: . .::..: .. ::::.:: .::.:..::::::::::::::.:::.
XP_011 RTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVA
260 270 280 290 300 310
280 290
pF1KB9 QSLFSISKEHLECR
XP_011 TPIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPT
320 330 340 350 360 370
>>XP_011541043 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 536 init1: 298 opt: 515 Z-score: 494.1 bits: 99.8 E(85289): 8.8e-21
Smith-Waterman score: 516; 40.0% identity (64.9% similar) in 265 aa overlap (30-272:48-306)
10 20 30 40 50
pF1KB9 MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSN-HATNVMSTATGLHYSVPSC
.:. : ... : . . . : :: .
XP_011 SDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQF
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB9 HYGN-QPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAED----P--TAADFKQEL
.. ::. : : : : ::.. : . : : :: . : ..... .:
XP_011 LLSQTQPGQQG-----LQPNLLPFPQQQ-SGLLLPQTGPGLASQAFGHPGLPGSSLEPHL
80 90 100 110 120 130
120 130 140 150 160
pF1KB9 RRKSKL-VEEPID----MDSP-EIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEF
. ...: : . . : : ...::::::. :: ::::::.:: .:: :.. ..:..:
XP_011 EASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDF
140 150 160 170 180 190
170 180 190 200 210
pF1KB9 SQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANE--------RKRKR
::::: ::: :.::::: :::: .: :::..::. . . .. .. ::::.
XP_011 SQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKK
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB9 RTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLN
::.: . .::..: .. ::::.:: .::.:..::::::::::::::.:::.
XP_011 RTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVA
260 270 280 290 300 310
280 290
pF1KB9 QSLFSISKEHLECR
XP_011 TPIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPT
320 330 340 350 360 370
291 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:30:10 2016 done: Sat Nov 5 19:30:11 2016
Total Scan time: 5.750 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]