Result of FASTA (ccds) for
pF1KB9692
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9692, 243 aa
1>>>pF1KB9692 243 - 243 aa - 243 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9028+/-0.000703; mu= 13.5851+/- 0.043
mean_var=114.9473+/-23.877, 0's: 0 Z-trim(113.4): 180 B-trim: 696 in 2/49
Lambda= 0.119626
statistics sampled from 13842 (14053) to 13842 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.432), width: 16
Scan time: 1.880
The best scores are: opt bits E(32554)
CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 ( 243) 1688 301.3 3.9e-82
CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 ( 242) 997 182.0 3.1e-46
CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 ( 290) 788 146.0 2.5e-35
CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 ( 289) 771 143.1 1.9e-34
CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 ( 106) 540 102.8 9.5e-23
CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 ( 224) 439 85.7 2.9e-17
CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 ( 230) 427 83.6 1.2e-16
CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 ( 217) 410 80.7 9e-16
CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 ( 235) 392 77.6 8.2e-15
CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 ( 233) 381 75.7 3e-14
CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 ( 153) 373 74.1 5.8e-14
CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 ( 270) 360 72.1 4.1e-13
CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 ( 269) 358 71.8 5.2e-13
CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 ( 222) 353 70.8 8.3e-13
CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 ( 255) 316 64.5 7.7e-11
CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 ( 251) 315 64.3 8.6e-11
>>CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 (243 aa)
initn: 1688 init1: 1688 opt: 1688 Z-score: 1588.1 bits: 301.3 E(32554): 3.9e-82
Smith-Waterman score: 1688; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243)
10 20 30 40 50 60
pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG
190 200 210 220 230 240
pF1KB9 DKK
:::
CCDS11 DKK
>>CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 (242 aa)
initn: 947 init1: 645 opt: 997 Z-score: 943.6 bits: 182.0 E(32554): 3.1e-46
Smith-Waterman score: 997; 62.0% identity (81.6% similar) in 245 aa overlap (1-239:1-241)
10 20 30 40 50
pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGS---FQHPSQ-IQE
::::::: ::::::.::::.: :::: : :..: ..:::: ::: ::: :. .:.
CCDS88 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP--GGSAPGFQHASHHVQD
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 FYH-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAA
:.: : :..:.. ::::::...:::: ..::::. : ::::.::: . ..::: ::: .:
CCDS88 FFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 ASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRK
.. .: .:. ::. .::::::.: ::: ::::::::::::::::::::::::::
CCDS88 NTNSSEGQGHLNQNSSPSLMFPWMRPHAP-GRRSGRQTYSRYQTLELEKEFLFNPYLTRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADE
:::::::::::::::::::::::::::::::::::.:... ..:..:.. :. . .:
CCDS88 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEE
180 190 200 210 220 230
240
pF1KB9 GDAQKGDKK
. .:
CCDS88 KEENKD
240
>>CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 (290 aa)
initn: 941 init1: 699 opt: 788 Z-score: 747.6 bits: 146.0 E(32554): 2.5e-35
Smith-Waterman score: 826; 52.1% identity (69.4% similar) in 265 aa overlap (16-235:24-287)
10 20 30 40
pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG
::.. :.:::: :: ..::: .. .:: :..:
CCDS22 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG
10 20 30 40 50 60
50 60 70
pF1KB9 ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP-----------
. ::: . ::..: .. .: :: :
CCDS22 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP
70 80 90 100 110 120
80 90 100 110 120
pF1KB9 ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS
:. .::::.:..::::: :::: .: .: . .:::: ::: ......::. . .::
CCDS22 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS
130 140 150 160 170
130 140 150 160 170 180
pF1KB9 PSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER
::.:.::::::::: :::::::::::.:::::::::::::::::::::::::::.::::
CCDS22 SSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB9 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-KQKLERAPEAADEGDAQKGDKK
::::::::::::::::::::::: :. : .. : :.. .. : ::
CCDS22 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN
240 250 260 270 280 290
>>CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 (289 aa)
initn: 890 init1: 467 opt: 771 Z-score: 731.8 bits: 143.1 E(32554): 1.9e-34
Smith-Waterman score: 809; 51.7% identity (69.1% similar) in 265 aa overlap (16-235:24-286)
10 20 30 40
pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG
::.. :.:::: :: ..::: .. .:: :..:
CCDS56 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG
10 20 30 40 50 60
50 60 70
pF1KB9 ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP-----------
. ::: . ::..: .. .: :: :
CCDS56 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP
70 80 90 100 110 120
80 90 100 110 120
pF1KB9 ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS
:. .::::.:..::::: :::: .: .: . .:::: ::: ......::. . .::
CCDS56 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS
130 140 150 160 170
130 140 150 160 170 180
pF1KB9 PSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER
::.:.:::::::: :::::::::::.:::::::::::::::::::::::::::.::::
CCDS56 SSPSQMFPWMRPQAP-GRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB9 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-KQKLERAPEAADEGDAQKGDKK
::::::::::::::::::::::: :. : .. : :.. .. : ::
CCDS56 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN
240 250 260 270 280
>>CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 (106 aa)
initn: 536 init1: 536 opt: 540 Z-score: 521.9 bits: 102.8 E(32554): 9.5e-23
Smith-Waterman score: 540; 78.6% identity (88.3% similar) in 103 aa overlap (134-235:1-103)
110 120 130 140 150 160
pF1KB9 LVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEK
.::::::::: :::::::::::.:::::::
CCDS56 MFPWMRPQAAPGRRRGRQTYSRFQTLELEK
10 20 30
170 180 190 200 210 220
pF1KB9 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-K
::::::::::::::::::::.::::::::::::::::::::::::::: :. : .. : :
CCDS56 EFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETK
40 50 60 70 80 90
230 240
pF1KB9 QKLERAPEAADEGDAQKGDKK
.. .. : ::
CCDS56 KEAQELEEDRAEGLTN
100
>>CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 (224 aa)
initn: 429 init1: 348 opt: 439 Z-score: 423.5 bits: 85.7 E(32554): 2.9e-17
Smith-Waterman score: 439; 41.6% identity (59.7% similar) in 238 aa overlap (1-223:1-222)
10 20 30 40 50
pF1KB9 MSSYFVNSLFS-KYKTG-ESLRPNY--YDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQE
:::::::: : .: ::. . :. :.:. : :. :::. : : .
CCDS11 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAP-YGPGPG---QDKGFATS
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQD-PDL---VQYADCKL
:. :.. . . . :: .: :: . . .: ::.. : . . .::
CCDS11 SYYPPAGGGYG--RAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRKSDCA-
60 70 80 90 100
120 130 140 150 160
pF1KB9 AAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGR-------RRGRQTYSRYQTLELEKEF
: .:: .:.. : ..:::. . . . :::::::.:::::::::::
CCDS11 QDKSVFGE----TEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEF
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB9 LFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKL
.: ::::.::::..::: :::::.::::::::::::::. : :. .:: :::
CCDS11 HYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKES-KLLSASQLSAEEEEEKQAE
170 180 190 200 210 220
230 240
pF1KB9 ERAPEAADEGDAQKGDKK
>>CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 (230 aa)
initn: 478 init1: 353 opt: 427 Z-score: 412.2 bits: 83.6 E(32554): 1.2e-16
Smith-Waterman score: 496; 43.1% identity (63.8% similar) in 246 aa overlap (2-243:3-224)
10 20 30 40 50
pF1KB9 MSSYFVNSLFSKYKTGESLRPNYY--DCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEF
:::.::.::::: .: :: : .:.:: . . : :: ...:.: : . .
CCDS54 MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPN-SQRSG--YG-AGAGAFA--STVPGL
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 YHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQR--QSLFGAQDPDLVQYADCKLAAA
:. : : :.: : . .: .. :: : :.. : . ::.. : : .
CCDS54 YNVNS-----PLYQSPFA-SGYGLGADAYGNLPCASYDQNIPGLCS-DLAKGA-CDKTDE
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 SGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKR
..: ::.. ...:::: ... :.::::::.::::::::::: :: ::::.:
CCDS54 GALHGAAEAN------FRIYPWMR-SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRR
110 120 130 140 150
180 190 200 210 220 230
pF1KB9 RIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEG
:::..::: :::::.::::::::::::::. ::. :.. : . : :::..
CCDS54 RIEIAHALCLTERQIKIWFQNRRMKWKKEH-KDEGPTAAAAPEGAVPSAA--ATAAADKA
160 170 180 190 200 210
240
pF1KB9 DAQKGDKK
: . :..
CCDS54 DEEDDDEEEEDEEE
220 230
>>CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 (217 aa)
initn: 470 init1: 347 opt: 410 Z-score: 396.7 bits: 80.7 E(32554): 9e-16
Smith-Waterman score: 493; 41.6% identity (65.2% similar) in 233 aa overlap (1-223:1-217)
10 20 30 40 50
pF1KB9 MSS-YFVNSLFSKYKTGESLR-----PNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQI
::: :..:.::::: .. :. :. .:.::.. :: :: .::.:: ...
CCDS11 MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASN-PQRPG--YGAGSGASFA--ASM
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 QEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAA
: .: : .... :. .: : :: .: . . . . .: :
CCDS11 QGLYPGGGGMAG----QSAAGVYAAG-----YGLEPSSFNMHCAPFEQNLSGVCPGDSAK
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 ASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRK
:.: :. ... . : ...:::: .... :.::::::.::::::::::: .: ::::.
CCDS11 AAGAKEQRDSDLAAESNFRIYPWMR-SSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSS----KCEQEELEKQKLERAPE
::::..:.: :::::.::::::::::::::: : :.. . : :: :..
CCDS11 RRIEIAHTLCLTERQIKIWFQNRRMKWKKEN-KTAGPGTTGQDRAEAEEEEEE
170 180 190 200 210
240
pF1KB9 AADEGDAQKGDKK
>>CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 (235 aa)
initn: 426 init1: 353 opt: 392 Z-score: 379.4 bits: 77.6 E(32554): 8.2e-15
Smith-Waterman score: 392; 37.7% identity (61.4% similar) in 215 aa overlap (1-206:1-201)
10 20 30 40 50
pF1KB9 MSSYFVN-SLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYH
:.:::.: :: . :... :: . : : :. .. ... :. ::
CCDS88 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYD----PVRHFSTYGAAVAQNRIYSTPFY-
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLG
.: :.: . .: : .. . . :...... . . . : . .
CCDS88 -------SP-QENVVFSSSRG-PYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSS
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 EEAEGSEQSPSPT-QLFPWMRPQAA-------AGRRRGRQTYSRYQTLELEKEFLFNPYL
:... . :. . . :..:::. . . : :::::: ::::::::::::: :: ::
CCDS88 EQGRTAPQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 TRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEA
::.::::...:: :::::.::::::::::::::.:
CCDS88 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKRE
170 180 190 200 210 220
240
pF1KB9 ADEGDAQKGDKK
CCDS88 ETEEEKQKE
230
>>CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 (233 aa)
initn: 426 init1: 344 opt: 381 Z-score: 369.2 bits: 75.7 E(32554): 3e-14
Smith-Waterman score: 411; 40.4% identity (60.4% similar) in 225 aa overlap (1-205:1-214)
10 20 30 40 50
pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQ---DLGGRPTVVYGPSSGGSFQHPSQIQE-
::::::: : :: :. : ..: .: .. :.: :. . :..
CCDS54 MSSYFVNPTFPG-----SL-PSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTS
10 20 30 40 50
60 70 80 90 100
pF1KB9 --FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQD-----PDLVQYAD
::. .:. . . ...: . .. : .: . : : :. ::
CCDS54 PCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQ-QY--
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 CKLAAASGLGE--EAEGSEQSPSPTQLFPWM-RPQAAAGR------RRGRQTYSRYQTLE
: ..:: :. . ::.... . . ..::: : .. :: :::::::.::::::
CCDS54 -KPDSSSGQGKALHDEGADRKYT-SPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLE
120 130 140 150 160
170 180 190 200 210 220
pF1KB9 LEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEEL
::::: :: ::::.::::...:: :::::.:::::::::::::::
CCDS54 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA
170 180 190 200 210 220
230 240
pF1KB9 EKQKLERAPEAADEGDAQKGDKK
CCDS54 KAGE
230
243 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:22:09 2016 done: Fri Nov 4 18:22:09 2016
Total Scan time: 1.880 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]