Result of FASTA (omim) for
pF1KB9520
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9520, 445 aa
1>>>pF1KB9520 445 - 445 aa - 445 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1661+/-0.000333; mu= 13.4985+/- 0.021
mean_var=219.7386+/-46.760, 0's: 0 Z-trim(123.2): 448 B-trim: 3926 in 2/55
Lambda= 0.086521
statistics sampled from 41976 (42568) to 41976 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.499), width: 16
Scan time: 9.690
The best scores are: opt bits E(85289)
NP_009163 (OMIM: 604525) histamine H3 receptor [Ho ( 445) 3043 392.1 1.5e-108
XP_005260323 (OMIM: 604525) PREDICTED: histamine H ( 453) 3043 392.1 1.5e-108
XP_016883112 (OMIM: 604525) PREDICTED: histamine H ( 399) 2445 317.4 4.2e-86
NP_067637 (OMIM: 606792) histamine H4 receptor iso ( 390) 635 91.5 4.3e-18
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 624 90.2 1.2e-17
XP_016855648 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_011542349 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855644 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855643 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_005273089 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855646 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_011542343 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855642 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_011542347 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_011542346 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_011542345 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855641 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_011542348 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855652 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
NP_000731 (OMIM: 100100,118494) muscarinic acetylc ( 590) 538 79.6 2.4e-14
XP_016855650 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855649 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855651 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855647 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
XP_016855645 (OMIM: 100100,118494) PREDICTED: musc ( 590) 538 79.6 2.4e-14
NP_001307846 (OMIM: 118496) muscarinic acetylcholi ( 532) 522 77.5 9.1e-14
NP_036257 (OMIM: 118496) muscarinic acetylcholine ( 532) 522 77.5 9.1e-14
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic ( 460) 518 77.0 1.2e-13
NP_000729 (OMIM: 118510) muscarinic acetylcholine ( 460) 518 77.0 1.2e-13
NP_000732 (OMIM: 118495) muscarinic acetylcholine ( 479) 502 75.0 4.8e-13
NP_001006633 (OMIM: 118493) muscarinic acetylcholi ( 466) 470 71.0 7.6e-12
NP_001006631 (OMIM: 118493) muscarinic acetylcholi ( 466) 470 71.0 7.6e-12
NP_000730 (OMIM: 118493) muscarinic acetylcholine ( 466) 470 71.0 7.6e-12
NP_001006632 (OMIM: 118493) muscarinic acetylcholi ( 466) 470 71.0 7.6e-12
NP_001006627 (OMIM: 118493) muscarinic acetylcholi ( 466) 470 71.0 7.6e-12
NP_001006630 (OMIM: 118493) muscarinic acetylcholi ( 466) 470 71.0 7.6e-12
NP_001006629 (OMIM: 118493) muscarinic acetylcholi ( 466) 470 71.0 7.6e-12
XP_011514071 (OMIM: 118493) PREDICTED: muscarinic ( 466) 470 71.0 7.6e-12
NP_001006628 (OMIM: 118493) muscarinic acetylcholi ( 466) 470 71.0 7.6e-12
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 459 69.6 2e-11
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 435 66.6 1.6e-10
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 427 65.6 3.1e-10
XP_011524435 (OMIM: 606792) PREDICTED: histamine H ( 127) 414 63.3 4.3e-10
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 409 63.3 1.4e-09
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 383 60.1 1.4e-08
NP_001091683 (OMIM: 600167) histamine H1 receptor ( 487) 379 59.6 2e-08
NP_001091682 (OMIM: 600167) histamine H1 receptor ( 487) 379 59.6 2e-08
XP_011531955 (OMIM: 600167) PREDICTED: histamine H ( 487) 379 59.6 2e-08
XP_016861772 (OMIM: 600167) PREDICTED: histamine H ( 487) 379 59.6 2e-08
XP_016861773 (OMIM: 600167) PREDICTED: histamine H ( 487) 379 59.6 2e-08
>>NP_009163 (OMIM: 604525) histamine H3 receptor [Homo s (445 aa)
initn: 3043 init1: 3043 opt: 3043 Z-score: 2069.6 bits: 392.1 E(85289): 1.5e-108
Smith-Waterman score: 3043; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
370 380 390 400 410 420
430 440
pF1KB9 RAFTKLLCPQKLKIQPHSSLEHCWK
:::::::::::::::::::::::::
NP_009 RAFTKLLCPQKLKIQPHSSLEHCWK
430 440
>>XP_005260323 (OMIM: 604525) PREDICTED: histamine H3 re (453 aa)
initn: 3043 init1: 3043 opt: 3043 Z-score: 2069.6 bits: 392.1 E(85289): 1.5e-108
Smith-Waterman score: 3043; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
370 380 390 400 410 420
430 440
pF1KB9 RAFTKLLCPQKLKIQPHSSLEHCWK
:::::::::::::::::::::::::
XP_005 RAFTKLLCPQKLKIQPHSSLEHCWKKMKKKTCL
430 440 450
>>XP_016883112 (OMIM: 604525) PREDICTED: histamine H3 re (399 aa)
initn: 2437 init1: 2437 opt: 2445 Z-score: 1666.8 bits: 317.4 E(85289): 4.2e-86
Smith-Waterman score: 2646; 96.5% identity (96.5% similar) in 405 aa overlap (41-445:1-391)
20 30 40 50 60 70
pF1KB9 NASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNN
::::::::::::::::::::::::::::::
XP_016 MALLIVATVLGNALVMLAFVADSSLRTQNN
10 20 30
80 90 100 110 120 130
pF1KB9 FFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISY
:::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 FFLLNLAISDFLVG--------------RWTFGRGLCKLWLVVDYLLCTSSAFNIVLISY
40 50 60 70
140 150 160 170 180 190
pF1KB9 DRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYA
80 90 100 110 120 130
200 210 220 230 240 250
pF1KB9 EFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQP
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB9 SPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSS
200 210 220 230 240 250
320 330 340 350 360 370
pF1KB9 SRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLC
260 270 280 290 300 310
380 390 400 410 420 430
pF1KB9 WAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQ
320 330 340 350 360 370
440
pF1KB9 KLKIQPHSSLEHCWK
:::::::::::::::
XP_016 KLKIQPHSSLEHCWKKMKKKTCL
380 390
>>NP_067637 (OMIM: 606792) histamine H4 receptor isoform (390 aa)
initn: 961 init1: 312 opt: 635 Z-score: 445.8 bits: 91.5 E(85289): 4.3e-18
Smith-Waterman score: 896; 39.5% identity (63.6% similar) in 423 aa overlap (29-439:10-382)
10 20 30 40 50 60
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
.: . ..:: .:.:. : .::::::.::::
NP_067 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFV
10 20 30 40
70 80 90 100 110 120
pF1KB9 ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
.:..:: ....:.::::::::.::.. ::::.:..: .: ::. .: .::..::::::.
NP_067 VDKNLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLF-EWDFGKEICVFWLTTDYLLCTA
50 60 70 80 90 100
130 140 150 160 170
pF1KB9 SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAIL---SWEYL
:..:::::::::.:::. :::::.:. . . : :. :::::::. :: :: ::.
NP_067 SVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWK--
110 120 130 140 150
180 190 200 210 220 230
pF1KB9 SGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAR
. :: .: :: .::.: .: ::: : . :..::..::
NP_067 DEGS-----ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIY---------------
160 170 180 190
240 250 260 270 280 290
pF1KB9 EAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEA-GEATLGGGGG
:. :.. : : : .::... :.. : ..
NP_067 ---------------------WSLWKRDHLSRCQSHP---GLTAVSSNICGHSFRGRLSS
200 210 220 230
300 310 320 330 340
pF1KB9 GGSVASPTSSSGS-SSRGTERPRSLKRGSKPSASSASLEKRMKMVSQS----FTQR--FR
:... : .: :. .: :: .:. . .: .. ..: ::: . :: .
NP_067 RRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVE
240 250 260 270 280 290
350 360 370 380 390 400
pF1KB9 LSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVP-DYWYETSFWLLWANSAVN
: : :..:::::.....:..:::::.:. :. . . : . ::. .::: : :: ::
NP_067 LLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVN
300 310 320 330 340 350
410 420 430 440
pF1KB9 PVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK
:.::::::. :..:: :..: .: :: :
NP_067 PLLYPLCHKRFQKAFLKIFC---IKKQPLPSQHSRSVSS
360 370 380 390
>>NP_000674 (OMIM: 104250) alpha-2C adrenergic receptor (462 aa)
initn: 528 init1: 305 opt: 624 Z-score: 437.6 bits: 90.2 E(85289): 1.2e-17
Smith-Waterman score: 640; 31.5% identity (59.4% similar) in 451 aa overlap (4-427:13-452)
10 20 30 40
pF1KB9 MERAPPDGPLNASGAL---AGEAAAAGGA-----RG-FSAAWTAVLAALMA
: :: ::::: .: .: :.:: :: .::. .: :::...
NP_000 MASPALAAALAVAAAAGP-NASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVG
10 20 30 40 50
50 60 70 80 90 100
pF1KB9 LLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTF
.::: ::.::.::..: ... .::. .:.::..:: .:.::... .:. . : . : :
NP_000 FLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 GRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVL
:. : ..:..: :.:::: .. :: ::. :::.:: : .. ::. .. ::..
NP_000 GQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKR-TPRRVKATIVAVWLI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 AFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIY
. .. : ..: :.. :. : .::.: .. ::.: : . . .:
NP_000 SAVISFPPLVSLYRQPDGAAYPQCGLNDE---TWYIL-SSCIGSFFAPCLIMGL----VY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB9 LNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCW-GCWQKGHGEAMPLHRYGVGEAA
: : ..:: : .: : :.:. : : ..:: : : :..
NP_000 ARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHC-APPPADVEPDESS
240 250 260 270 280
290 300 310 320
pF1KB9 VGAE----------AGEATLG--GGGGG--GSVASPTSSSGSSSRGTERPRSLKRGSKPS
..:: .:. : ::.:: :. :.: .. ... ... : : :. :
NP_000 AAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRAS
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB9 ASSAS--LEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACH
. :. : .: . :. .. .:... . :::....: ::: :. . . . . :.
NP_000 SRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICR
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB9 GHC-VPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCW
: :: .. ::. . ::..:::.: . ...:::.: ..:
NP_000 EACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
410 420 430 440 450 460
pF1KB9 K
>>XP_016855648 (OMIM: 100100,118494) PREDICTED: muscarin (590 aa)
initn: 506 init1: 342 opt: 538 Z-score: 378.4 bits: 79.6 E(85289): 2.4e-14
Smith-Waterman score: 538; 34.0% identity (70.4% similar) in 250 aa overlap (8-252:38-283)
10 20 30
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGAR----GFSAAW
: :.: : ::. .. :. : ..:
XP_016 TTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRA-AGNFSSPDGTTDDPLGGHTVW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 TAVLAALMA-LLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYV
.:. :... .: ..:..:: ::...: ....:.: ::.:::.:: .:...:.. . :..
XP_016 QVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 PYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRA
:.. .::..: : :::..::. ..:..:...::.::..:.:: ..:::.. :.::
XP_016 TYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR-TTKRA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 VRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFL
. :.::..:.:..:::: :.:. : ..: :.:. .:. . . . .. :. :
XP_016 GVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 SVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPL
.:.. :: . ..::. .: : .:.: : : :
XP_016 IMTILYWRIYKETEKRTK-ELAGL-QASGTEAETENFVHPTGSSRSCSSYELQQQSMKRS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 HRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSAS
XP_016 NRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRA
310 320 330 340 350 360
>>XP_011542349 (OMIM: 100100,118494) PREDICTED: muscarin (590 aa)
initn: 506 init1: 342 opt: 538 Z-score: 378.4 bits: 79.6 E(85289): 2.4e-14
Smith-Waterman score: 538; 34.0% identity (70.4% similar) in 250 aa overlap (8-252:38-283)
10 20 30
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGAR----GFSAAW
: :.: : ::. .. :. : ..:
XP_011 TTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRA-AGNFSSPDGTTDDPLGGHTVW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 TAVLAALMA-LLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYV
.:. :... .: ..:..:: ::...: ....:.: ::.:::.:: .:...:.. . :..
XP_011 QVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 PYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRA
:.. .::..: : :::..::. ..:..:...::.::..:.:: ..:::.. :.::
XP_011 TYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR-TTKRA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 VRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFL
. :.::..:.:..:::: :.:. : ..: :.:. .:. . . . .. :. :
XP_011 GVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 SVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPL
.:.. :: . ..::. .: : .:.: : : :
XP_011 IMTILYWRIYKETEKRTK-ELAGL-QASGTEAETENFVHPTGSSRSCSSYELQQQSMKRS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 HRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSAS
XP_011 NRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRA
310 320 330 340 350 360
>>XP_016855644 (OMIM: 100100,118494) PREDICTED: muscarin (590 aa)
initn: 506 init1: 342 opt: 538 Z-score: 378.4 bits: 79.6 E(85289): 2.4e-14
Smith-Waterman score: 538; 34.0% identity (70.4% similar) in 250 aa overlap (8-252:38-283)
10 20 30
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGAR----GFSAAW
: :.: : ::. .. :. : ..:
XP_016 TTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRA-AGNFSSPDGTTDDPLGGHTVW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 TAVLAALMA-LLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYV
.:. :... .: ..:..:: ::...: ....:.: ::.:::.:: .:...:.. . :..
XP_016 QVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 PYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRA
:.. .::..: : :::..::. ..:..:...::.::..:.:: ..:::.. :.::
XP_016 TYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR-TTKRA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 VRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFL
. :.::..:.:..:::: :.:. : ..: :.:. .:. . . . .. :. :
XP_016 GVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 SVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPL
.:.. :: . ..::. .: : .:.: : : :
XP_016 IMTILYWRIYKETEKRTK-ELAGL-QASGTEAETENFVHPTGSSRSCSSYELQQQSMKRS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 HRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSAS
XP_016 NRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRA
310 320 330 340 350 360
>>XP_016855643 (OMIM: 100100,118494) PREDICTED: muscarin (590 aa)
initn: 506 init1: 342 opt: 538 Z-score: 378.4 bits: 79.6 E(85289): 2.4e-14
Smith-Waterman score: 538; 34.0% identity (70.4% similar) in 250 aa overlap (8-252:38-283)
10 20 30
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGAR----GFSAAW
: :.: : ::. .. :. : ..:
XP_016 TTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRA-AGNFSSPDGTTDDPLGGHTVW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 TAVLAALMA-LLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYV
.:. :... .: ..:..:: ::...: ....:.: ::.:::.:: .:...:.. . :..
XP_016 QVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 PYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRA
:.. .::..: : :::..::. ..:..:...::.::..:.:: ..:::.. :.::
XP_016 TYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR-TTKRA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 VRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFL
. :.::..:.:..:::: :.:. : ..: :.:. .:. . . . .. :. :
XP_016 GVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 SVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPL
.:.. :: . ..::. .: : .:.: : : :
XP_016 IMTILYWRIYKETEKRTK-ELAGL-QASGTEAETENFVHPTGSSRSCSSYELQQQSMKRS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 HRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSAS
XP_016 NRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRA
310 320 330 340 350 360
>>XP_005273089 (OMIM: 100100,118494) PREDICTED: muscarin (590 aa)
initn: 506 init1: 342 opt: 538 Z-score: 378.4 bits: 79.6 E(85289): 2.4e-14
Smith-Waterman score: 538; 34.0% identity (70.4% similar) in 250 aa overlap (8-252:38-283)
10 20 30
pF1KB9 MERAPPDGPLNASGALAGEAAAAGGAR----GFSAAW
: :.: : ::. .. :. : ..:
XP_005 TTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRA-AGNFSSPDGTTDDPLGGHTVW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 TAVLAALMA-LLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYV
.:. :... .: ..:..:: ::...: ....:.: ::.:::.:: .:...:.. . :..
XP_005 QVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 PYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRA
:.. .::..: : :::..::. ..:..:...::.::..:.:: ..:::.. :.::
XP_005 TYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR-TTKRA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 VRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFL
. :.::..:.:..:::: :.:. : ..: :.:. .:. . . . .. :. :
XP_005 GVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 SVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPL
.:.. :: . ..::. .: : .:.: : : :
XP_005 IMTILYWRIYKETEKRTK-ELAGL-QASGTEAETENFVHPTGSSRSCSSYELQQQSMKRS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 HRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSAS
XP_005 NRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRA
310 320 330 340 350 360
445 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:01:04 2016 done: Sun Nov 6 13:01:05 2016
Total Scan time: 9.690 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]