Result of FASTA (omim) for
pF1KB8940
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8940, 297 aa
1>>>pF1KB8940 297 - 297 aa - 297 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1722+/-0.000333; mu= 0.1900+/- 0.021
mean_var=246.7343+/-50.536, 0's: 0 Z-trim(123.5): 250 B-trim: 782 in 2/57
Lambda= 0.081651
statistics sampled from 43281 (43546) to 43281 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.511), width: 16
Scan time: 7.860
The best scores are: opt bits E(85289)
NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 1963 243.3 4.4e-64
NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 839 110.9 2.9e-24
NP_004396 (OMIM: 126255) homeobox protein DLX-2 [H ( 328) 318 49.6 1e-05
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 310 48.6 2e-05
NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 305 48.0 2.6e-05
NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 303 47.8 3.4e-05
NP_004088 (OMIM: 600034) homeobox protein EMX1 [Ho ( 290) 296 46.9 5.5e-05
NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 294 46.7 7.2e-05
NP_796374 (OMIM: 605955) homeobox protein Nkx-6.2 ( 277) 292 46.4 7.4e-05
NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 291 46.3 8.3e-05
NP_612138 (OMIM: 601911,616788) homeobox protein D ( 240) 289 46.0 8.5e-05
XP_016872278 (OMIM: 605955) PREDICTED: homeobox pr ( 277) 287 45.8 0.00011
NP_005212 (OMIM: 220600,600028) homeobox protein D ( 289) 287 45.9 0.00012
NP_001129743 (OMIM: 217095,611770) homeobox protei ( 301) 286 45.8 0.00013
NP_064448 (OMIM: 605211) barH-like 1 homeobox prot ( 327) 285 45.7 0.00015
NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 283 45.4 0.00015
XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 283 45.4 0.00015
XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 282 45.3 0.0002
NP_001091639 (OMIM: 611074) brain-specific homeobo ( 233) 277 44.6 0.00022
NP_001925 (OMIM: 601911,616788) homeobox protein D ( 168) 274 44.1 0.00022
XP_016879780 (OMIM: 601911,616788) PREDICTED: home ( 168) 274 44.1 0.00022
NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 279 44.9 0.00023
NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 277 44.6 0.00024
NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 277 44.7 0.0003
NP_835221 (OMIM: 600029) homeobox protein DLX-1 is ( 255) 273 44.2 0.00033
NP_001418 (OMIM: 131310) homeobox protein engraile ( 333) 275 44.5 0.00034
XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 274 44.4 0.00036
NP_001417 (OMIM: 131290) homeobox protein engraile ( 392) 275 44.6 0.00039
NP_001182446 (OMIM: 186770) T-cell leukemia homeob ( 257) 270 43.8 0.00042
NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 ( 364) 271 44.1 0.0005
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 267 43.6 0.0008
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 267 43.6 0.0008
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 267 43.6 0.0008
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 267 43.6 0.0008
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 267 43.6 0.0008
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 267 43.6 0.0008
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 267 43.6 0.0008
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 267 43.6 0.0008
NP_005211 (OMIM: 104510,190320,600525) homeobox pr ( 287) 263 43.0 0.00081
NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 265 43.4 0.00086
NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 ( 367) 262 43.0 0.0011
NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 257 42.2 0.0011
XP_011538047 (OMIM: 186770) PREDICTED: T-cell leuk ( 269) 258 42.4 0.0012
XP_016867292 (OMIM: 220600,600028) PREDICTED: home ( 161) 252 41.5 0.0013
XP_005250242 (OMIM: 220600,600028) PREDICTED: home ( 161) 252 41.5 0.0013
NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapie ( 264) 256 42.2 0.0014
NP_001476 (OMIM: 601135) homeobox protein GBX-2 is ( 348) 258 42.5 0.0014
NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 258 42.5 0.0014
NP_005213 (OMIM: 600030) homeobox protein DLX-6 [H ( 293) 254 42.0 0.0017
NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 254 42.0 0.0018
>>NP_002439 (OMIM: 106600,142983,189500,608874) homeobox (303 aa)
initn: 1963 init1: 1963 opt: 1963 Z-score: 1271.5 bits: 243.3 E(85289): 4.4e-64
Smith-Waterman score: 1963; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:7-303)
10 20 30 40 50
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAPAADMTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 FSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 TAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 AAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMY
250 260 270 280 290 300
pF1KB8 HLT
:::
NP_002 HLT
>>NP_002440 (OMIM: 123101,168500,168550,604757) homeobox (267 aa)
initn: 829 init1: 600 opt: 839 Z-score: 556.6 bits: 110.9 E(85289): 2.9e-24
Smith-Waterman score: 911; 58.9% identity (78.9% similar) in 275 aa overlap (25-297:16-267)
10 20 30 40 50
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPK-VSPSLLPFSVEA
..:...:. . . :. : .:. . :. : :::::::
NP_002 MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEA
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLK
::.:.. : ::.. :.:.. .::.. .:: . .. :: .: :: :: .:
NP_002 LMSDKKPP--KEASPLPAESA-SAGATLRPLLL--SGHGAREA-HSPGPL--------VK
60 70 80 90
120 130 140 150 160 170
pF1KB8 LPEDALVKAESPEKPERTPWMQSP-RFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQL
: : ::.:. : . . ::: : :.:::: :..:: .::::::::::::::::::.::
NP_002 PFETASVKSENSE--DGAAWMQEPGRYSPPP-RHMSPTTCTLRKHKTNRKPRTPFTTSQL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 LALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_002 LALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB8 MLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
::: ..:.: ::...: . ::.:::: ::.: .::. :::::.. :::.::::.
NP_002 MLP-SSFSLPFPISSPLQA-----ASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS
220 230 240 250 260
>>NP_004396 (OMIM: 126255) homeobox protein DLX-2 [Homo (328 aa)
initn: 314 init1: 246 opt: 318 Z-score: 223.7 bits: 49.6 E(85289): 1e-05
Smith-Waterman score: 343; 31.0% identity (56.1% similar) in 287 aa overlap (18-297:30-286)
10 20 30 40
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKV
:.::::: :.. ....... ::.
NP_004 MTGVFDSLVADMHSTQIAASSTYHQHQQPPSGGGAG--PGGNSSSSSSL------HKPQE
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 SPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRP
::.: : :. : .:. .. :.::.. : : . .:. . .:
NP_004 SPTL-PVST-----------ATDSSYYTNQQHPAGGGGGG--GSPYAHMGSYQYQASGLN
60 70 80 90
110 120 130 140 150 160
pF1KB8 LGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLR-KHKTNR
.:. . : : : . : : .:: . : . : : . : : :
NP_004 NVPYSAKSSYDLGYTA---AYTSYAPYGTS--SSPANNEPEKEDLEPEIRIVNGKPKKVR
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB8 KPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEA
:::: ... :: ::.:.:.. :::.. ::::...::.::.:::::::::::.: :.. ..
NP_004 KPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKS
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB8 -ELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQ----RAALPVAPV
:. . . . :: : : :...::. .. . :..:: . .. .:
NP_004 GEIPSEQHPGASASPPCA---SPPVSAPASWDFGVPQRMAGGGGPGSGGSGAGSSGSSPS
220 230 240 250 260 270
290
pF1KB8 GLYTAHVG-YSMYHLT
. .: .: : :: :
NP_004 SAASAFLGNYPWYHQTSGSASHLQATAPLLHPTQTPQPHHHHHHHGGGGAPVSAGTIF
280 290 300 310 320
>>NP_038463 (OMIM: 601881,611038) retinal homeobox prote (346 aa)
initn: 227 init1: 227 opt: 310 Z-score: 218.3 bits: 48.6 E(85289): 2e-05
Smith-Waterman score: 332; 32.8% identity (55.5% similar) in 265 aa overlap (46-287:4-256)
20 30 40 50 60 70
pF1KB8 GKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADH--RKPGAKESA
: .:.. : .: : :.::.. :
NP_038 MHLPGCAPAMADGSFS--LAGHLLRSPGGSTSR
10 20 30
80 90 100 110 120 130
pF1KB8 LAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEK
: :.. . . ::. :. :: : : :: . . : ::.. . :
NP_038 LHSIEAILGFTKDDGILGTFPAERGARGAKERDRRLG--ARPACPKAPEEG-SEPSPPPA
40 50 60 70 80
140 150 160 170
pF1KB8 PERTPWMQSPR-FSP--PPARRLSP-----PACTLRK-------HKTNRKPRTPFTTAQL
: .: ...:: . : : : :: :: : .: .:. :: ::: ::
NP_038 PAPAPEYEAPRPYCPKEPGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQL
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB8 LALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKP
::: :....: .. : :......: :..:..:::::::: .: .. :. ..:. .:
NP_038 HELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSP
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB8 ML-----PPAAFGLSFPLG-GPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYS
.: ::.: :: ::: ::.. .. ::..: :.. : : : ::
NP_038 LLSFSRSPPSAT-LS-PLGAGPGSGGGPAGGAL-----PLESWLGPPLPGGGATALQSLP
210 220 230 240 250 260
pF1KB8 MYHLT
NP_038 GFGPPAQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPR
270 280 290 300 310 320
>>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa)
initn: 297 init1: 215 opt: 305 Z-score: 216.3 bits: 48.0 E(85289): 2.6e-05
Smith-Waterman score: 305; 32.8% identity (56.6% similar) in 244 aa overlap (17-254:15-246)
10 20 30 40 50 60
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEAL
.: . : : :. . ....: . : . . ::
NP_057 MEPGMLGPHNLPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGA---FSGGYH
10 20 30 40 50
70 80 90 100 110
pF1KB8 MADHRKPGAKESALAPSEGVQAAG----GSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGG
:. :... . : : :: .: . .:: ::: . ::: .:. : :: ..::
NP_057 GASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPG-PSGLG--GAGG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 LLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTA
: : . ... : .: :: :: .::.. : . : .:::: :. .
NP_057 LAGLTFPWMDSGRRFAK-DRLTAALSP-FSG--TRRIGHPYQN-RTPPKRKKPRTSFSRS
120 130 140 150 160
180 190 200 210 220 230
pF1KB8 QLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRL--QEAELEKLKM
:.: :::.: ...::. :::: ....: .:..::: ::::::.: .: .: : :. .
NP_057 QVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHR-
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB8 AAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMY
:.. .: .: :: :
NP_057 AGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
230 240 250 260 270 280
>>NP_004378 (OMIM: 108900,187500,217095,225250,600584,61 (324 aa)
initn: 296 init1: 254 opt: 303 Z-score: 214.3 bits: 47.8 E(85289): 3.4e-05
Smith-Waterman score: 328; 32.0% identity (52.0% similar) in 275 aa overlap (46-292:5-269)
20 30 40 50 60 70
pF1KB8 GKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALA
: ..:. ::::. .. ... . .:
NP_004 MFPSPALTPT--PFSVKDILNLEQQQRSLAAAGE
10 20 30
80 90 100 110 120 130
pF1KB8 PSEGVQA--AGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEK
: ..: : .: . . : . ..:.: . : . .: . : : . :
NP_004 LSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELG---RAPSPAKCASAFPAA
40 50 60 70 80
140 150 160 170
pF1KB8 PERTPWMQSPRFSPPPA---RRLSPPACTLRK----HKTN------------RKPRTPFT
: : : .: :: : . :.:.: .::. ::::. :.
NP_004 PAFYPRAYS---DPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFS
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB8 TAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRL-QEAELEKLK
::. :::.:.:..::: :: ...: :.:: ::::::::::: : :: :. :: .
NP_004 QAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVG
150 160 170 180 190 200
240 250 260 270 280
pF1KB8 MAAKPMLPPAAFGLSFPL----GGPAAVAAAAGASLYGAS-GPFQRAALPVAP-VGLYTA
. : :: : .. :. : : .: : ::.. .:. : :. : : .
NP_004 LPPPP--PPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAAC
210 220 230 240 250 260
290
pF1KB8 HVGYSMYHLT
:::
NP_004 SPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
270 280 290 300 310 320
>>NP_004088 (OMIM: 600034) homeobox protein EMX1 [Homo s (290 aa)
initn: 277 init1: 213 opt: 296 Z-score: 210.5 bits: 46.9 E(85289): 5.5e-05
Smith-Waterman score: 298; 33.9% identity (55.7% similar) in 230 aa overlap (7-230:42-255)
10 20 30
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAA
: .: : .: .: :.: . ..:.. :
NP_004 AAPGRGALPRARLPRTAPAAATMFQPAAKRGFTIE-SLVAKDGGTGGGTGGGGAGSHLLA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 MGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGS
.:.:: .: :: : :.: :.:.. . . ::.:... : :
NP_004 AAASEEPLRPT-----------ALNYPH--PSAAEAAFVSGFPAAAAAGAGRSLYGGP-E
80 90 100 110
100 110 120 130 140 150
pF1KB8 LGAPDAPSSPRPLGH--FSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLS
: :.: . : : ..:. : .. :. . . ::. :: . .
NP_004 LVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASD
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 PPACTLRKHKT-NRKP---RTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQV
: : : ::: :: :. .::: ::: :....:. ::: ....::::.::::
NP_004 VPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 KIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASG
:.::::::.: :: :. : :
NP_004 KVWFQNRRTKYKR-QKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND
240 250 260 270 280 290
>>NP_005512 (OMIM: 186770) T-cell leukemia homeobox prot (330 aa)
initn: 205 init1: 205 opt: 294 Z-score: 208.4 bits: 46.7 E(85289): 7.2e-05
Smith-Waterman score: 294; 29.5% identity (54.5% similar) in 264 aa overlap (16-266:53-304)
10 20 30 40
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAK
: . ::.:.: ...:. :.:.:. :.
NP_005 QILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGP
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB8 PKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAGGSA--QPLGVP--PGSLGAPD
. . :. : ... : .. .:. : ..::.. . :: :.
NP_005 GGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPAHRPLAG
90 100 110 120 130 140
110 120 130 140 150
pF1KB8 APSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQS------PRFSPPPARRLSP
: . :.::. :: .: . . . :::.: ::. : . .:
NP_005 AVAHPQPLAT----GLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTP
150 160 170 180 190
160 170 180 190 200 210
pF1KB8 PACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQ
: :.: :::: :: :. ::..:....::. :::: ....:..:..::: :::
NP_005 P-----KKK---KPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQ
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB8 NRRAKAKRLQEAELEKLKMAAKPML---PPAAFGLSFPLGGPAAVAAAAGASLYGASGPF
:::.: .: : : .. :. .: :: :. :: . ..::.
NP_005 NRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQ
260 270 280 290 300 310
280 290
pF1KB8 QRAALPVAPVGLYTAHVGYSMYHLT
NP_005 PWSDDSTKITSVTSVASACE
320 330
>>NP_796374 (OMIM: 605955) homeobox protein Nkx-6.2 [Hom (277 aa)
initn: 283 init1: 183 opt: 292 Z-score: 208.2 bits: 46.4 E(85289): 7.4e-05
Smith-Waterman score: 292; 30.3% identity (60.6% similar) in 221 aa overlap (27-233:6-215)
10 20 30 40 50 60
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEAL
:.: . ..: ..: .. :. :.: :.:.....
NP_796 MDTNRPGAFVLSSAPLAALHNMAEMKTS--LFPYALQG-
10 20 30
70 80 90 100 110 120
pF1KB8 MADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKL
: . :. ..:. . . . : .. :: : :. :. . :: : : .:.
NP_796 PAGFKAPAL--GGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFG
40 50 60 70 80 90
130 140 150 160
pF1KB8 PEDALVK------AESPEKP--------ERTPWMQSPRFSPPPARRLSPPACTLRKHKTN
: :... :: : .: . .:: ..::.. : .: . .: : .
NP_796 PAAAVARGYPKPLAELPGRPPIFWPGVVQGAPW-RDPRLAGP-----APAGGVLDKDGKK
100 110 120 130 140
170 180 190 200 210 220
pF1KB8 RKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQE
.. : :. :..:::. :.: .::. :::... ::..::.:::.::::::.: .. .
NP_796 KHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHA
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB8 AELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYT
::. . :
NP_796 AEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSP
210 220 230 240 250 260
>>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa)
initn: 322 init1: 212 opt: 291 Z-score: 207.3 bits: 46.3 E(85289): 8.3e-05
Smith-Waterman score: 303; 32.4% identity (58.1% similar) in 222 aa overlap (26-240:32-240)
10 20 30 40 50
pF1KB8 MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPF
::. . .:.. . :..: .. ::
NP_066 EAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLPA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 SVEALMADHRKPGAKES--ALAPSEGVQAAGGSAQPLGVPPGSLGA-PDAPSSPRPLGHF
: .: : . :. .:::. ... . : .::: .: : :: :
NP_066 SFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTV---S
70 80 90 100 110
120 130 140 150 160
pF1KB8 SVGGLLKLP--EDA--LVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRK
:.::: ..: :.. .:: . ::. . :.. : : .:: :: :
NP_066 SLGGL-NFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNR-TPPK---RK-----K
120 130 140 150 160
170 180 190 200 210 220
pF1KB8 PRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAE
::: :. .:. ::..:....::. :::: ...::..:..::: ::::::.: .: :
NP_066 PRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEE
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB8 LEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAH
: .. :. ..
NP_066 REAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVT
230 240 250 260 270 280
297 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:10:48 2016 done: Sat Nov 5 01:10:49 2016
Total Scan time: 7.860 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]