Result of FASTA (omim) for
pF1KB8936
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8936, 285 aa
1>>>pF1KB8936 285 - 285 aa - 285 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2235+/-0.000276; mu= 16.4016+/- 0.017
mean_var=74.1518+/-15.140, 0's: 0 Z-trim(120.2): 30 B-trim: 918 in 2/54
Lambda= 0.148941
statistics sampled from 35112 (35145) to 35112 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.412), width: 16
Scan time: 8.280
The best scores are: opt bits E(85289)
NP_542787 (OMIM: 608597) neuralized-like protein 2 ( 285) 1952 428.0 1e-119
NP_001265464 (OMIM: 608597) neuralized-like protei ( 261) 1702 374.2 1.4e-103
NP_001005408 (OMIM: 615865) neuralized-like protei (1560) 220 56.4 4.1e-07
NP_115818 (OMIM: 615865) neuralized-like protein 4 (1562) 220 56.4 4.1e-07
NP_001295107 (OMIM: 615893) E3 ubiquitin-protein l ( 315) 211 53.9 4.5e-07
NP_001136123 (OMIM: 615893) E3 ubiquitin-protein l ( 555) 211 54.1 7e-07
XP_011538637 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 290) 185 48.3 2e-05
XP_011538635 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 556) 185 48.5 3.4e-05
XP_005270326 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 557) 185 48.5 3.4e-05
NP_004201 (OMIM: 603804) E3 ubiquitin-protein liga ( 574) 185 48.5 3.4e-05
XP_016872398 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 580) 185 48.5 3.5e-05
XP_011538634 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 594) 185 48.5 3.5e-05
XP_011538633 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 612) 185 48.5 3.6e-05
XP_005270327 (OMIM: 603804) PREDICTED: E3 ubiquiti ( 499) 162 43.5 0.00095
>>NP_542787 (OMIM: 608597) neuralized-like protein 2 iso (285 aa)
initn: 1952 init1: 1952 opt: 1952 Z-score: 2270.4 bits: 428.0 E(85289): 1e-119
Smith-Waterman score: 1952; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 APGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 APGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR
190 200 210 220 230 240
250 260 270 280
pF1KB8 LVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE
:::::::::::::::::::::::::::::::::::::::::::::
NP_542 LVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE
250 260 270 280
>>NP_001265464 (OMIM: 608597) neuralized-like protein 2 (261 aa)
initn: 1695 init1: 1695 opt: 1702 Z-score: 1980.6 bits: 374.2 E(85289): 1.4e-103
Smith-Waterman score: 1702; 96.9% identity (98.1% similar) in 259 aa overlap (1-257:1-258)
10 20 30 40 50 60
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 APGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR
190 200 210 220 230 240
250 260 270 280
pF1KB8 LVQLEYGL--PSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE
:::::::. :. . :::
NP_001 LVQLEYGFFFPQCHP-CRLCAA
250 260
>>NP_001005408 (OMIM: 615865) neuralized-like protein 4 (1560 aa)
initn: 434 init1: 218 opt: 220 Z-score: 248.7 bits: 56.4 E(85289): 4.1e-07
Smith-Waterman score: 273; 31.7% identity (53.4% similar) in 221 aa overlap (25-242:913-1082)
10 20 30 40 50
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVC
::: . : :. .. .::::.:. ..:::.
NP_001 TGPMDNSLATSNTATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAGYAHGLV
890 900 910 920 930 940
60 70 80 90 100 110
pF1KB8 FSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFA
:: . : .:: :..:: . : : ::::::.: :. ..: :
NP_001 FSTKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGP------------G------
950 960 970 980
120 130 140 150 160 170
pF1KB8 ITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQ
: ...:. ::.: : :: . . . : : : :
NP_001 ---------------AGGGGPGLPPSL---PELRTKTTWMVSSCEV--RRDG-------Q
990 1000 1010
180 190 200 210 220 230
pF1KB8 LYELNV---LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVD
: ..: : . ::.:: : . :::...::::::.: :. :. ..::.:
NP_001 LQRMNYGRNLERLGVGSRVGV----RRGADDTMHILVDGEDMGPAATGI--AKNVWAVLD
1020 1030 1040 1050 1060 1070
240 250 260 270 280
pF1KB8 VFASTKSVRLVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE
... ...: .:
NP_001 LYGPVRGVSIVSSTRLEESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLE
1080 1090 1100 1110 1120 1130
>>NP_115818 (OMIM: 615865) neuralized-like protein 4 iso (1562 aa)
initn: 434 init1: 218 opt: 220 Z-score: 248.7 bits: 56.4 E(85289): 4.1e-07
Smith-Waterman score: 273; 31.7% identity (53.4% similar) in 221 aa overlap (25-242:915-1084)
10 20 30 40 50
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVC
::: . : :. .. .::::.:. ..:::.
NP_115 TGPMDNSLATSNTATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAGYAHGLV
890 900 910 920 930 940
60 70 80 90 100 110
pF1KB8 FSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFA
:: . : .:: :..:: . : : ::::::.: :. ..: :
NP_115 FSTKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGP------------G------
950 960 970 980
120 130 140 150 160 170
pF1KB8 ITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQ
: ...:. ::.: : :: . . . : : : :
NP_115 ---------------AGGGGPGLPPSL---PELRTKTTWMVSSCEV--RRDG-------Q
990 1000 1010
180 190 200 210 220 230
pF1KB8 LYELNV---LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVD
: ..: : . ::.:: : . :::...::::::.: :. :. ..::.:
NP_115 LQRMNYGRNLERLGVGSRVGV----RRGADDTMHILVDGEDMGPAATGI--AKNVWAVLD
1020 1030 1040 1050 1060 1070
240 250 260 270 280
pF1KB8 VFASTKSVRLVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE
... ...: .:
NP_115 LYGPVRGVSIVSSTRLEESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLE
1080 1090 1100 1110 1120 1130
>>NP_001295107 (OMIM: 615893) E3 ubiquitin-protein ligas (315 aa)
initn: 155 init1: 155 opt: 211 Z-score: 248.0 bits: 53.9 E(85289): 4.5e-07
Smith-Waterman score: 211; 37.5% identity (63.5% similar) in 104 aa overlap (18-115:32-133)
10 20 30 40
pF1KB8 MAAASEPVDSGALWGLERP---EPPPTRFH-RVHGANIRVDPSGTRA
:: : : ::: ...: :.:.: . ::
NP_001 GNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAP--RFHAQAKGKNVRLDGHSRRA
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 TRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPA--SLAPVPEFSL
:: .:: .:: :...:. . ... . :: : ::.:.:: ::. : .:...
NP_001 TRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYAC
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 PDLVNLGHTWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVG
::::. :. :.
NP_001 PDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWAL
120 130 140 150 160 170
>>NP_001136123 (OMIM: 615893) E3 ubiquitin-protein ligas (555 aa)
initn: 189 init1: 155 opt: 211 Z-score: 244.6 bits: 54.1 E(85289): 7e-07
Smith-Waterman score: 211; 37.5% identity (63.5% similar) in 104 aa overlap (18-115:32-133)
10 20 30 40
pF1KB8 MAAASEPVDSGALWGLERP---EPPPTRFH-RVHGANIRVDPSGTRA
:: : : ::: ...: :.:.: . ::
NP_001 GNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAP--RFHAQAKGKNVRLDGHSRRA
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 TRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPA--SLAPVPEFSL
:: .:: .:: :...:. . ... . :: : ::.:.:: ::. : .:...
NP_001 TRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYAC
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 PDLVNLGHTWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVG
::::. :. :.
NP_001 PDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWAL
120 130 140 150 160 170
>>XP_011538637 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (290 aa)
initn: 177 init1: 113 opt: 185 Z-score: 218.3 bits: 48.3 E(85289): 2e-05
Smith-Waterman score: 185; 33.3% identity (63.5% similar) in 96 aa overlap (23-115:100-195)
10 20 30 40 50
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFH-RVHGANIRVDPSGTRATRVESFAH
: :: ...:..: .: : . : :: .
XP_011 GGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCN
70 80 90 100 110 120
60 70 80 90 100
pF1KB8 GVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAP--VPEFSLPDLVNLGH
.. :: .:. . ..: .:. : : ::::.:. ::. . : .:... ::::. .
XP_011 AITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB8 TWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYS
:. :.
XP_011 FWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTR
190 200 210 220 230 240
>>XP_011538635 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (556 aa)
initn: 185 init1: 113 opt: 185 Z-score: 214.4 bits: 48.5 E(85289): 3.4e-05
Smith-Waterman score: 185; 33.3% identity (63.5% similar) in 96 aa overlap (23-115:44-139)
10 20 30 40 50
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFH-RVHGANIRVDPSGTRATRVESFAH
: :: ...:..: .: : . : :: .
XP_011 GGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCN
20 30 40 50 60 70
60 70 80 90 100
pF1KB8 GVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAP--VPEFSLPDLVNLGH
.. :: .:. . ..: .:. : : ::::.:. ::. . : .:... ::::. .
XP_011 AITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB8 TWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYS
:. :.
XP_011 FWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTR
140 150 160 170 180 190
>>XP_005270326 (OMIM: 603804) PREDICTED: E3 ubiquitin-pr (557 aa)
initn: 185 init1: 113 opt: 185 Z-score: 214.4 bits: 48.5 E(85289): 3.4e-05
Smith-Waterman score: 185; 33.3% identity (63.5% similar) in 96 aa overlap (23-115:45-140)
10 20 30 40 50
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFH-RVHGANIRVDPSGTRATRVESFAH
: :: ...:..: .: : . : :: .
XP_005 GGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCN
20 30 40 50 60 70
60 70 80 90 100
pF1KB8 GVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAP--VPEFSLPDLVNLGH
.. :: .:. . ..: .:. : : ::::.:. ::. . : .:... ::::. .
XP_005 AITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB8 TWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYS
:. :.
XP_005 FWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTR
140 150 160 170 180 190
>>NP_004201 (OMIM: 603804) E3 ubiquitin-protein ligase N (574 aa)
initn: 185 init1: 113 opt: 185 Z-score: 214.2 bits: 48.5 E(85289): 3.4e-05
Smith-Waterman score: 185; 33.3% identity (63.5% similar) in 96 aa overlap (23-115:62-157)
10 20 30 40 50
pF1KB8 MAAASEPVDSGALWGLERPEPPPTRFH-RVHGANIRVDPSGTRATRVESFAH
: :: ...:..: .: : . : :: .
NP_004 GGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCN
40 50 60 70 80 90
60 70 80 90 100
pF1KB8 GVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAP--VPEFSLPDLVNLGH
.. :: .:. . ..: .:. : : ::::.:. ::. . : .:... ::::. .
NP_004 AITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSG
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB8 TWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYS
:. :.
NP_004 FWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTR
160 170 180 190 200 210
285 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:04:56 2016 done: Sat Nov 5 20:04:57 2016
Total Scan time: 8.280 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]