Result of FASTA (omim) for
pF1KB8896
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8896, 223 aa
1>>>pF1KB8896 223 - 223 aa - 223 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0580+/-0.000401; mu= 14.8452+/- 0.025
mean_var=57.1517+/-11.350, 0's: 0 Z-trim(111.5): 29 B-trim: 39 in 1/51
Lambda= 0.169652
statistics sampled from 20084 (20110) to 20084 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.236), width: 16
Scan time: 6.060
The best scores are: opt bits E(85289)
NP_001630 (OMIM: 104770) serum amyloid P-component ( 223) 1501 375.6 3.7e-104
NP_001315986 (OMIM: 123260) C-reactive protein iso ( 224) 777 198.4 8.2e-51
NP_000558 (OMIM: 123260) C-reactive protein isofor ( 224) 777 198.4 8.2e-51
NP_001013680 (OMIM: 613442) pentraxin-4 isoform 2 ( 473) 286 78.3 2.3e-14
NP_001315537 (OMIM: 613442) pentraxin-4 isoform 1 ( 478) 286 78.3 2.4e-14
NP_002514 (OMIM: 600750) neuronal pentraxin-2 prec ( 431) 279 76.6 7.1e-14
NP_055108 (OMIM: 609474) neuronal pentraxin recept ( 500) 267 73.7 6.2e-13
NP_002513 (OMIM: 602367) neuronal pentraxin-1 prec ( 432) 263 72.7 1.1e-12
NP_002843 (OMIM: 602492) pentraxin-related protein ( 381) 225 63.4 6.1e-10
NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 234 66.0 9e-10
NP_001315987 (OMIM: 123260) C-reactive protein iso ( 91) 202 57.4 8.8e-09
>>NP_001630 (OMIM: 104770) serum amyloid P-component pre (223 aa)
initn: 1501 init1: 1501 opt: 1501 Z-score: 1990.9 bits: 375.6 E(85289): 3.7e-104
Smith-Waterman score: 1501; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD
130 140 150 160 170 180
190 200 210 220
pF1KB8 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
:::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
190 200 210 220
>>NP_001315986 (OMIM: 123260) C-reactive protein isoform (224 aa)
initn: 769 init1: 582 opt: 777 Z-score: 1033.2 bits: 198.4 E(85289): 8.2e-51
Smith-Waterman score: 777; 51.8% identity (79.5% similar) in 224 aa overlap (1-222:1-223)
10 20 30 40 50 60
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS
:.: :: . ::::: .::..::.: :.::::.:: :..:.: .:: :::. ::.:.. :.
NP_001 MEK-LLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYT
10 20 30 40 50
70 80 90 100 110
pF1KB8 DLS--RAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWE
.:: :.::.::: :. .:::.:.. . ::. .: .. .: : ::::::.:::
NP_001 ELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 SSSGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYM
:.:::.:::..: : :.:.:..:: : :. .:.:::::::.::.:. :::.::.::.. :
NP_001 SASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNM
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 WDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
:: :: :..: . : : :. :.:.:.::.::..: :. :: .:
NP_001 WDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP
180 190 200 210 220
>>NP_000558 (OMIM: 123260) C-reactive protein isoform 1 (224 aa)
initn: 769 init1: 582 opt: 777 Z-score: 1033.2 bits: 198.4 E(85289): 8.2e-51
Smith-Waterman score: 777; 51.8% identity (79.5% similar) in 224 aa overlap (1-222:1-223)
10 20 30 40 50 60
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS
:.: :: . ::::: .::..::.: :.::::.:: :..:.: .:: :::. ::.:.. :.
NP_000 MEK-LLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYT
10 20 30 40 50
70 80 90 100 110
pF1KB8 DLS--RAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWE
.:: :.::.::: :. .:::.:.. . ::. .: .. .: : ::::::.:::
NP_000 ELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 SSSGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYM
:.:::.:::..: : :.:.:..:: : :. .:.:::::::.::.:. :::.::.::.. :
NP_000 SASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNM
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 WDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
:: :: :..: . : : :. :.:.:.::.::..: :. :: .:
NP_000 WDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP
180 190 200 210 220
>>NP_001013680 (OMIM: 613442) pentraxin-4 isoform 2 [Hom (473 aa)
initn: 275 init1: 161 opt: 286 Z-score: 378.7 bits: 78.3 E(85289): 2.3e-14
Smith-Waterman score: 295; 32.5% identity (60.2% similar) in 191 aa overlap (25-202:265-448)
10 20 30 40 50
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITP-LEKPLQNFT
: ..::: : : .: ...: . :. ..
NP_001 GSHRVLSGTAPKDPRQQAWSPQVPGEICGVGPTLVFPNAS-TRNVVFLSPGFVTALRALS
240 250 260 270 280 290
60 70 80 90 100 110
pF1KB8 LCFRAYSDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGR-HKVTSK-VIEKFPAPV
.: . . .: .:.:: :. ::.:... :. :: : : : . .....: .
NP_001 FCSWVRTASGRLGTLLSYATEDNDNKLVLH----GRDSLLPGSIHFVIGDPAFRELPLQL
300 310 320 330 340
120 130 140 150 160
pF1KB8 -------HICVSWESSSGIAEFWIN-GTPLVKKG--LRQGYFVEAQPKIVLGQEQDSYGG
:::: : :..: ..:.. :: : .:.:: . ..:::::::: ::
NP_001 LLDGQWHHICVIWTSTQG--RYWLHVDRRLVATGSRFREGYEIPPGGSLVLGQEQDSVGG
350 360 370 380 390 400
170 180 190 200 210 220
pF1KB8 KFDRSQSFVGEIGDLYMWDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLV
:: :..::: .. : .:: .: : .. . : .:.. .
NP_001 GFDSSEAFVGSMSGLAIWDRALVPGEVANLAIGKEFPTGAILTLANAALAGGFVQGANCT
410 420 430 440 450 460
pF1KB8 WV
NP_001 CLERCP
470
>>NP_001315537 (OMIM: 613442) pentraxin-4 isoform 1 prec (478 aa)
initn: 275 init1: 161 opt: 286 Z-score: 378.7 bits: 78.3 E(85289): 2.4e-14
Smith-Waterman score: 295; 32.5% identity (60.2% similar) in 191 aa overlap (25-202:270-453)
10 20 30 40 50
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITP-LEKPLQNFT
: ..::: : : .: ...: . :. ..
NP_001 GSHRVLSGTAPKDPRQQAWSPQVPGEICGVGPTLVFPNAS-TRNVVFLSPGFVTALRALS
240 250 260 270 280 290
60 70 80 90 100 110
pF1KB8 LCFRAYSDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGR-HKVTSK-VIEKFPAPV
.: . . .: .:.:: :. ::.:... :. :: : : : . .....: .
NP_001 FCSWVRTASGRLGTLLSYATEDNDNKLVLH----GRDSLLPGSIHFVIGDPAFRELPLQL
300 310 320 330 340 350
120 130 140 150 160
pF1KB8 -------HICVSWESSSGIAEFWIN-GTPLVKKG--LRQGYFVEAQPKIVLGQEQDSYGG
:::: : :..: ..:.. :: : .:.:: . ..:::::::: ::
NP_001 LLDGQWHHICVIWTSTQG--RYWLHVDRRLVATGSRFREGYEIPPGGSLVLGQEQDSVGG
360 370 380 390 400 410
170 180 190 200 210 220
pF1KB8 KFDRSQSFVGEIGDLYMWDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLV
:: :..::: .. : .:: .: : .. . : .:.. .
NP_001 GFDSSEAFVGSMSGLAIWDRALVPGEVANLAIGKEFPTGAILTLANAALAGGFVQGANCT
420 430 440 450 460 470
pF1KB8 WV
NP_001 CLERCP
>>NP_002514 (OMIM: 600750) neuronal pentraxin-2 precurso (431 aa)
initn: 213 init1: 152 opt: 279 Z-score: 370.1 bits: 76.6 E(85289): 7.1e-14
Smith-Waterman score: 283; 28.8% identity (60.9% similar) in 215 aa overlap (9-213:200-414)
10 20 30
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFP---RESV
:.:..::. .. . ....: : . :.
NP_002 ERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSL
170 180 190 200 210 220
40 50 60 70 80 90
pF1KB8 TDHVN-LITPLEKPLQN---FTLCFRAYSDLSRAYSL-FSYNTQGRDNELLVYKERVGEY
..: : ..: : . ::.:. :. : . . ::: . :. ::... . .
NP_002 PLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPI
230 240 250 260 270 280
100 110 120 130 140
pF1KB8 SLYIGRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGTPL-VKKGLRQGYFVEAQPK
: :. . . .. . ::::.: . .:. : . .: : . ..: . ..
NP_002 ELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGV
290 300 310 320 330 340
150 160 170 180 190 200
pF1KB8 IVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENILS-AYQGTPLPANILDWQALN
..::::::. ::.:: .:.::::.... .:: :: ..:.. : .: .:.::. : :
NP_002 LILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIVNIANCSTNMPGNIIPWVDNN
350 360 370 380 390 400
210 220
pF1KB8 YEIRGYVIIKPLVWV
.. :
NP_002 VDVFGGASKWPVETCEERLLDL
410 420 430
>>NP_055108 (OMIM: 609474) neuronal pentraxin receptor [ (500 aa)
initn: 159 init1: 159 opt: 267 Z-score: 353.2 bits: 73.7 E(85289): 6.2e-13
Smith-Waterman score: 267; 30.9% identity (61.1% similar) in 162 aa overlap (49-205:316-476)
20 30 40 50 60 70
pF1KB8 AHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLC--FRAYSDLSRAYSLFSYNTQGR
: :: : .:. :. . . :::.. :.
NP_055 SAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPFSYSVPGQ
290 300 310 320 330 340
80 90 100 110 120 130
pF1KB8 DNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGTPLVKK
::... . . : :. . . . : . :::..: . .:. . .: : .
NP_055 ANEIVLLEAGHEPMELLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQDGE-LQGS
350 360 370 380 390 400
140 150 160 170 180 190
pF1KB8 GLRQGYFVEAQPK--IVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENILSAYQG
: . . .:. ..::::::. ::.:: .:.:::.:... .:: .: : ..:. .
NP_055 GENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANC
410 420 430 440 450 460
200 210 220
pF1KB8 T-PLPANILDWQALNYEIRGYVIIKPLVWV
: :: .:.: :.
NP_055 TAPLLGNVLPWEDKLVEAFGGATKAAFDVCKGRAKA
470 480 490 500
>>NP_002513 (OMIM: 602367) neuronal pentraxin-1 precurso (432 aa)
initn: 224 init1: 148 opt: 263 Z-score: 348.9 bits: 72.7 E(85289): 1.1e-12
Smith-Waterman score: 263; 29.6% identity (56.8% similar) in 213 aa overlap (13-213:213-418)
10 20 30 40
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVF--VFPRESVTDHVN
: :: . . : : .:: .. ...
NP_002 TLEEGKGGPRNDTEERVKIETALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAK
190 200 210 220 230 240
50 60 70 80 90
pF1KB8 LITPLEKPLQNFTLCFRAYSDLSRAYSL-FSYNTQGRDNELLVYKERVGEYSLYIGRHKV
. : . . ::.:. :. . . . ::: . :. :::.. . :. . : .
NP_002 VKKSLPE-MYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEW--GNNPMEI---LI
250 260 270 280 290
100 110 120 130 140 150
pF1KB8 TSKVIEKFPAPV------HICVSWESSSGIAEFWINGTPLVK-KGLRQGYFVEAQPKIVL
..:: :.: . ::::.: . .:. : . .:: . ..: . .. : .::
NP_002 NDKVA-KLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVL
300 310 320 330 340 350
160 170 180 190 200 210
pF1KB8 GQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENI--LSAYQGTPLPANILDWQALNYE
:::::. :: :: .:.::::.. . .:: : : .. :.. . : .:.. : . :
NP_002 GQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIE
360 370 380 390 400 410
220
pF1KB8 IRGYVIIKPLVWV
: :
NP_002 IYGGATKWTFEACRQIN
420 430
>>NP_002843 (OMIM: 602492) pentraxin-related protein PTX (381 aa)
initn: 110 init1: 91 opt: 225 Z-score: 299.5 bits: 63.4 E(85289): 6.1e-10
Smith-Waterman score: 225; 24.7% identity (58.8% similar) in 194 aa overlap (29-213:184-375)
10 20 30 40 50
pF1KB8 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRES--VTDHVNLITPLEKPLQNFTLCF
.:: .: . :. . :.. :..:. :.
NP_002 EELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMR--LESFSACI
160 170 180 190 200 210
60 70 80 90 100 110
pF1KB8 RAY-SDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGR-HKVTSKVIEKFPAPVHIC
. .:. ::::.:. :. .: . . :. .:...... .. .:.:
NP_002 WVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLC
220 230 240 250 260 270
120 130 140 150 160 170
pF1KB8 VSWESSSGIAEFWINGT-PLVKKGLRQGYFVEAQPKIVLGQEQDS--YGGKFDRSQSFVG
.:.: :.. .:.:: . . :..: . .:::... :: ::.. .: :
NP_002 GTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSG
280 290 300 310 320 330
180 190 200 210 220
pF1KB8 EIGDLYMWDSVLPPENI--LSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
.. . .::::: :.: .. .. . .::. : . . . .:
NP_002 RLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS
340 350 360 370 380
>>NP_699197 (OMIM: 611691) sushi, von Willebrand factor (3571 aa)
initn: 250 init1: 151 opt: 234 Z-score: 296.4 bits: 66.0 E(85289): 9e-10
Smith-Waterman score: 234; 33.5% identity (56.2% similar) in 176 aa overlap (49-217:1448-1621)
20 30 40 50 60 70
pF1KB8 AHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYSDLSRAYSL-FSYNTQ-GR
:. .: : :. . :. .:: .. :
NP_699 CETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGS
1420 1430 1440 1450 1460 1470
80 90 100 110 120 130
pF1KB8 DNELLVYKERVGEYSLYI-GRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGT-PLV
:: ::. . : . ::. ::.:.:. . :: ..: :..:: . .:.:
NP_699 DNTLLL-TDYNG-WVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDG
1480 1490 1500 1510 1520 1530
140 150 160 170 180 190
pF1KB8 KKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENILSAYQG
:: : . . .:::::::. : :. ..:::: :..: .:: :: :... : .
NP_699 GAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATS
1540 1550 1560 1570 1580 1590
200 210 220
pF1KB8 TPLP---ANILDWQALNYEIRGYVIIKPLVWV
: .:.: : . : : : :
NP_699 CPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVN
1600 1610 1620 1630 1640 1650
223 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:59:32 2016 done: Sat Nov 5 19:59:33 2016
Total Scan time: 6.060 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]