Result of FASTA (omim) for
pF1KB8653
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8653, 234 aa
1>>>pF1KB8653 234 - 234 aa - 234 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5361+/-0.000347; mu= 13.3672+/- 0.022
mean_var=73.2697+/-14.636, 0's: 0 Z-trim(115.3): 23 B-trim: 229 in 1/52
Lambda= 0.149835
statistics sampled from 25625 (25648) to 25625 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.301), width: 16
Scan time: 6.380
The best scores are: opt bits E(85289)
NP_004702 (OMIM: 603925) synaptogyrin-1 isoform 1a ( 233) 1588 352.2 4.5e-97
NP_663783 (OMIM: 603925) synaptogyrin-1 isoform 1b ( 191) 1121 251.2 9.4e-67
NP_663791 (OMIM: 603925) synaptogyrin-1 isoform 1c ( 192) 892 201.7 7.5e-52
NP_004200 (OMIM: 603927) synaptogyrin-3 [Homo sapi ( 229) 810 184.0 1.9e-46
NP_004701 (OMIM: 603926) synaptogyrin-2 isoform 1 ( 224) 733 167.3 1.9e-41
XP_005257849 (OMIM: 603926) PREDICTED: synaptogyri ( 275) 634 146.0 6.2e-35
XP_005258750 (OMIM: 608373) PREDICTED: synaptogyri ( 234) 498 116.5 3.9e-26
XP_005258751 (OMIM: 608373) PREDICTED: synaptogyri ( 234) 498 116.5 3.9e-26
NP_036583 (OMIM: 608373) synaptogyrin-4 [Homo sapi ( 234) 498 116.5 3.9e-26
XP_011524988 (OMIM: 608373) PREDICTED: synaptogyri ( 185) 405 96.4 3.6e-20
XP_016882030 (OMIM: 608373) PREDICTED: synaptogyri ( 185) 405 96.4 3.6e-20
NP_001307452 (OMIM: 603926) synaptogyrin-2 isoform ( 135) 384 91.8 6.4e-19
>>NP_004702 (OMIM: 603925) synaptogyrin-1 isoform 1a [Ho (233 aa)
initn: 1586 init1: 1374 opt: 1588 Z-score: 1863.7 bits: 352.2 E(85289): 4.5e-97
Smith-Waterman score: 1588; 99.6% identity (99.6% similar) in 234 aa overlap (1-234:1-233)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
:::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_004 FSQDYMDPSQDSSMPYAPYVEP-TGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
190 200 210 220 230
>>NP_663783 (OMIM: 603925) synaptogyrin-1 isoform 1b [Ho (191 aa)
initn: 1120 init1: 1120 opt: 1121 Z-score: 1319.4 bits: 251.2 E(85289): 9.4e-67
Smith-Waterman score: 1121; 87.2% identity (92.8% similar) in 195 aa overlap (1-195:1-191)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
:::::::::::::::::::::::::::::::::::::::::. :.:: .:.. : .
NP_663 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFK---DLS-
130 140 150 160 170
190 200 210 220 230
pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
:...: :..:
NP_663 FQEEYSTLFPASAQP
180 190
>>NP_663791 (OMIM: 603925) synaptogyrin-1 isoform 1c [Ho (192 aa)
initn: 890 init1: 890 opt: 892 Z-score: 1051.8 bits: 201.7 E(85289): 7.5e-52
Smith-Waterman score: 892; 81.4% identity (87.8% similar) in 172 aa overlap (31-195:25-192)
10 20 30 40 50
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSW-------LFSIVVFGSIVNEGYLNSAS
::: ::::::::::::::::::::
NP_663 MLTLEFGILEFDPSWIGSWTQRSWVSWRSRPGCELFSIVVFGSIVNEGYLNSAS
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 FWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQ
::::::::::::::::::::::::::::::::::::::::::::::::. :.:: .:..
NP_663 FWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 IGADSALFSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQG
: . :...: :..:
NP_663 ---DLS-FQEEYSTLFPASAQP
180 190
>>NP_004200 (OMIM: 603927) synaptogyrin-3 [Homo sapiens] (229 aa)
initn: 812 init1: 597 opt: 810 Z-score: 954.9 bits: 184.0 E(85289): 1.9e-46
Smith-Waterman score: 811; 51.7% identity (76.9% similar) in 238 aa overlap (1-234:1-229)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
:::...:::.::.:.:: ...:.:.:.:::.::.:::.::: ::::::.:. : : :.
NP_004 MEGASFGAGRAGAALDPVSFARRPQTLLRVASWVFSIAVFGPIVNEGYVNTDSGPELRCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
.: : .:: .:::.:. :::.: .: ::: : :::::.::..::: :.: :..:.::::
NP_004 FNGNAGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
::::.:.:::: . : . : ::::::::::::::..:.. .: :.::...:.: .:
NP_004 VGFCFLTNQWQRTAPGPATTQAG-DAARAAIAFSFFSILSWVALTVKALQRFRLGTDMSL
130 140 150 160 170
190 200 210 220 230
pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGT--YQQP--ANTFDTEPQGYQSQGY
:. . . : .:. : : : .:. :: ::.: ..:.:: :.::: .:
NP_004 FATEQL--STGASQAYPGY------PVGSGVEGTETYQSPPFTETLDTSPKGYQVPAY
180 190 200 210 220
>>NP_004701 (OMIM: 603926) synaptogyrin-2 isoform 1 [Hom (224 aa)
initn: 763 init1: 543 opt: 733 Z-score: 865.1 bits: 167.3 E(85289): 1.9e-41
Smith-Waterman score: 757; 49.4% identity (75.8% similar) in 231 aa overlap (1-230:1-219)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
::.:::::.::::.:: .. ::... :.: .:...::. : .::: :. . .:.
NP_004 MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
.::: .:: :: :.::::::. ..:..:.::::::.. ::: :..:. ::.:.::::
NP_004 FNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
::::.:.::: :..::: . :.:..::::.:::::::.:. : ::.:::. :.:.
NP_004 VGFCFLTNQWAVTNPKD--VLVGADSVRAAITFSFFSIFSWGVLASLAYQRYKAGVDD--
130 140 150 160 170
190 200 210 220 230
pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEP-QGYQSQGY
: :.:.::. : . :: : :... : .:::: : ..: .:::
NP_004 FIQNYVDPTPDPNTAYASY--PGASVD------NYQQPPFTQNAETTEGYQPPPVY
180 190 200 210 220
>>XP_005257849 (OMIM: 603926) PREDICTED: synaptogyrin-2 (275 aa)
initn: 623 init1: 543 opt: 634 Z-score: 748.1 bits: 146.0 E(85289): 6.2e-35
Smith-Waterman score: 634; 53.4% identity (81.6% similar) in 163 aa overlap (1-163:1-161)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
::.:::::.::::.:: .. ::... :.: .:...::. : .::: :. . .:.
XP_005 MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
.::: .:: :: :.::::::. ..:..:.::::::.. ::: :..:. ::.:.::::
XP_005 FNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
::::.:.::: :..::: . :.:..::::.:::::::.:.:
XP_005 VGFCFLTNQWAVTNPKD--VLVGADSVRAAITFSFFSIFSWVGWPGAGSWVKGGGGWGPP
130 140 150 160 170
190 200 210 220 230
pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
XP_005 PTCTLLCSPCRVCWPPWPTSATRLAWTTSSRITLTPLRTPTLPTPPTQVHLWTTTNSHPS
180 190 200 210 220 230
>>XP_005258750 (OMIM: 608373) PREDICTED: synaptogyrin-4 (234 aa)
initn: 500 init1: 346 opt: 498 Z-score: 590.3 bits: 116.5 E(85289): 3.9e-26
Smith-Waterman score: 498; 37.9% identity (68.2% similar) in 214 aa overlap (20-227:18-227)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
..:.:.:: :: .::..::.:....:: :. . ::
XP_005 MHIPKSLQELANSEAVQFLRRPKTITRVFEGVFSLIVFSSLLTDGYQNKMESPQLHCI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
: : :::..:..: ::::.:: .:.::. .:.... . : :. ....:: .::
XP_005 LNSNSVACSFAVGAGFLAFLSCLAFLVLDTQETRIAGTRFKTAFQLLDFILAVLWAVVWF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
.:::.:::::: : ::. : :...:.:::::.::::..: :: :::: .. :. .
XP_005 MGFCFLANQWQHSPPKEFLL--GSSSAQAAIAFTFFSILVWIFQAYLAFQ--DLRNDAPV
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 FSQDYMDPSQD--SSMPY----APYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
. ..: . ...: .: :.:::. ..... .: : :.
XP_005 PYKRFLDEGGMVLTTLPLPSANSPVNMPTTGPNSLSYASSALSPCLTAPKSPRLAMMPDN
180 190 200 210 220 230
>>XP_005258751 (OMIM: 608373) PREDICTED: synaptogyrin-4 (234 aa)
initn: 500 init1: 346 opt: 498 Z-score: 590.3 bits: 116.5 E(85289): 3.9e-26
Smith-Waterman score: 498; 37.9% identity (68.2% similar) in 214 aa overlap (20-227:18-227)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
..:.:.:: :: .::..::.:....:: :. . ::
XP_005 MHIPKSLQELANSEAVQFLRRPKTITRVFEGVFSLIVFSSLLTDGYQNKMESPQLHCI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
: : :::..:..: ::::.:: .:.::. .:.... . : :. ....:: .::
XP_005 LNSNSVACSFAVGAGFLAFLSCLAFLVLDTQETRIAGTRFKTAFQLLDFILAVLWAVVWF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
.:::.:::::: : ::. : :...:.:::::.::::..: :: :::: .. :. .
XP_005 MGFCFLANQWQHSPPKEFLL--GSSSAQAAIAFTFFSILVWIFQAYLAFQ--DLRNDAPV
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 FSQDYMDPSQD--SSMPY----APYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
. ..: . ...: .: :.:::. ..... .: : :.
XP_005 PYKRFLDEGGMVLTTLPLPSANSPVNMPTTGPNSLSYASSALSPCLTAPKSPRLAMMPDN
180 190 200 210 220 230
>>NP_036583 (OMIM: 608373) synaptogyrin-4 [Homo sapiens] (234 aa)
initn: 500 init1: 346 opt: 498 Z-score: 590.3 bits: 116.5 E(85289): 3.9e-26
Smith-Waterman score: 498; 37.9% identity (68.2% similar) in 214 aa overlap (20-227:18-227)
10 20 30 40 50 60
pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI
..:.:.:: :: .::..::.:....:: :. . ::
NP_036 MHIPKSLQELANSEAVQFLRRPKTITRVFEGVFSLIVFSSLLTDGYQNKMESPQLHCI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF
: : :::..:..: ::::.:: .:.::. .:.... . : :. ....:: .::
NP_036 LNSNSVACSFAVGAGFLAFLSCLAFLVLDTQETRIAGTRFKTAFQLLDFILAVLWAVVWF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL
.:::.:::::: : ::. : :...:.:::::.::::..: :: :::: .. :. .
NP_036 MGFCFLANQWQHSPPKEFLL--GSSSAQAAIAFTFFSILVWIFQAYLAFQ--DLRNDAPV
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 FSQDYMDPSQD--SSMPY----APYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
. ..: . ...: .: :.:::. ..... .: : :.
NP_036 PYKRFLDEGGMVLTTLPLPSANSPVNMPTTGPNSLSYASSALSPCLTAPKSPRLAMMPDN
180 190 200 210 220 230
>>XP_011524988 (OMIM: 608373) PREDICTED: synaptogyrin-4 (185 aa)
initn: 427 init1: 273 opt: 405 Z-score: 483.1 bits: 96.4 E(85289): 3.6e-20
Smith-Waterman score: 405; 38.3% identity (67.4% similar) in 175 aa overlap (59-227:8-178)
30 40 50 60 70 80
pF1KB8 RVVSWLFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLAL
:: : : :::..:..: ::::.:: .:.:
XP_011 MESPQLHCILNSNSVACSFAVGAGFLAFLSCLAFLVL
10 20 30
90 100 110 120 130 140
pF1KB8 DVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAAR
:. .:.... . : :. ....:: .::.:::.:::::: : ::. : :...:.
XP_011 DTQETRIAGTRFKTAFQLLDFILAVLWAVVWFMGFCFLANQWQHSPPKEFLL--GSSSAQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB8 AAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQD--SSMPY----APYVEP
:::::.::::..: :: :::: .. :. . . ..: . ...: .: :
XP_011 AAIAFTFFSILVWIFQAYLAFQ--DLRNDAPVPYKRFLDEGGMVLTTLPLPSANSPVNMP
100 110 120 130 140 150
210 220 230
pF1KB8 NTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY
.:::. ..... .: : :.
XP_011 TTGPNSLSYASSALSPCLTAPKSPRLAMMPDN
160 170 180
234 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:54:01 2016 done: Sat Nov 5 19:54:02 2016
Total Scan time: 6.380 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]