Result of FASTA (omim) for
pF1KB8525
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8525, 961 aa
1>>>pF1KB8525 961 - 961 aa - 961 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3434+/-0.000364; mu= 13.2521+/- 0.023
mean_var=142.8735+/-29.547, 0's: 0 Z-trim(118.2): 156 B-trim: 1323 in 1/54
Lambda= 0.107300
statistics sampled from 30787 (30977) to 30787 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.363), width: 16
Scan time: 13.570
The best scores are: opt bits E(85289)
NP_001461 (OMIM: 603540) gamma-aminobutyric acid t ( 961) 6486 1016.3 0
XP_005249039 (OMIM: 603540) PREDICTED: gamma-amino ( 966) 6486 1016.3 0
NP_068704 (OMIM: 603540) gamma-aminobutyric acid t ( 899) 5400 848.2 0
XP_006715110 (OMIM: 603540) PREDICTED: gamma-amino ( 904) 5400 848.2 0
NP_068703 (OMIM: 603540) gamma-aminobutyric acid t ( 844) 5355 841.2 0
XP_011512755 (OMIM: 603540) PREDICTED: gamma-amino ( 897) 5340 838.9 0
NP_001305982 (OMIM: 603540) gamma-aminobutyric aci ( 784) 5231 822.0 0
XP_016866165 (OMIM: 603540) PREDICTED: gamma-amino ( 778) 4936 776.3 0
XP_011512757 (OMIM: 603540) PREDICTED: gamma-amino ( 680) 4523 712.3 2.1e-204
NP_005449 (OMIM: 188890,607340) gamma-aminobutyric ( 941) 1590 258.4 1.3e-67
XP_016870820 (OMIM: 188890,607340) PREDICTED: gamm ( 843) 1421 232.2 8.8e-60
XP_005252373 (OMIM: 188890,607340) PREDICTED: gamm ( 683) 1162 192.0 8.8e-48
XP_016870821 (OMIM: 188890,607340) PREDICTED: gamm ( 683) 1162 192.0 8.8e-48
XP_016861284 (OMIM: 610464) PREDICTED: probable G- ( 814) 429 78.6 1.4e-13
XP_005247222 (OMIM: 610464) PREDICTED: probable G- ( 814) 429 78.6 1.4e-13
XP_016861285 (OMIM: 610464) PREDICTED: probable G- ( 814) 429 78.6 1.4e-13
NP_694547 (OMIM: 610464) probable G-protein couple ( 814) 429 78.6 1.4e-13
NP_001161743 (OMIM: 610464) probable G-protein cou ( 810) 419 77.1 4.2e-13
XP_016861286 (OMIM: 610464) PREDICTED: probable G- ( 810) 419 77.1 4.2e-13
XP_011510786 (OMIM: 610464) PREDICTED: probable G- ( 733) 377 70.5 3.5e-11
XP_011510789 (OMIM: 610464) PREDICTED: probable G- ( 733) 377 70.5 3.5e-11
NP_001269776 (OMIM: 604100) metabotropic glutamate ( 604) 239 49.1 8.2e-05
NP_001243741 (OMIM: 604100) metabotropic glutamate ( 743) 239 49.2 9.6e-05
NP_003986 (OMIM: 108961,602875,615923,616255) atri (1047) 237 49.0 0.00016
XP_005251535 (OMIM: 108961,602875,615923,616255) P (1050) 237 49.0 0.00016
XP_016856863 (OMIM: 108960) PREDICTED: atrial natr ( 704) 221 46.4 0.00064
XP_011514410 (OMIM: 601116) PREDICTED: metabotropi ( 552) 219 46.0 0.00065
XP_016867569 (OMIM: 601116) PREDICTED: metabotropi ( 629) 219 46.0 0.00072
XP_011514405 (OMIM: 601116) PREDICTED: metabotropi ( 629) 219 46.0 0.00072
XP_011514404 (OMIM: 601116) PREDICTED: metabotropi ( 703) 219 46.1 0.00079
XP_016867568 (OMIM: 601116) PREDICTED: metabotropi ( 703) 219 46.1 0.00079
XP_011514403 (OMIM: 601116) PREDICTED: metabotropi ( 703) 219 46.1 0.00079
XP_016867566 (OMIM: 601116) PREDICTED: metabotropi ( 703) 219 46.1 0.00079
XP_016867564 (OMIM: 601116) PREDICTED: metabotropi ( 703) 219 46.1 0.00079
XP_016867567 (OMIM: 601116) PREDICTED: metabotropi ( 703) 219 46.1 0.00079
XP_016867565 (OMIM: 601116) PREDICTED: metabotropi ( 703) 219 46.1 0.00079
XP_011514397 (OMIM: 601116) PREDICTED: metabotropi ( 714) 219 46.1 0.0008
XP_011514396 (OMIM: 601116) PREDICTED: metabotropi ( 747) 219 46.1 0.00083
XP_005245275 (OMIM: 108960) PREDICTED: atrial natr (1035) 221 46.5 0.00086
NP_000897 (OMIM: 108960) atrial natriuretic peptid (1061) 221 46.5 0.00088
NP_000565 (OMIM: 125240,613793) complement decay-a ( 381) 198 42.6 0.0046
NP_001287833 (OMIM: 125240,613793) complement deca ( 384) 198 42.6 0.0047
XP_016855956 (OMIM: 125240,613793) PREDICTED: comp ( 412) 198 42.6 0.0049
NP_001287832 (OMIM: 125240,613793) complement deca ( 439) 198 42.7 0.0052
NP_001108224 (OMIM: 125240,613793) complement deca ( 440) 198 42.7 0.0052
NP_001287831 (OMIM: 125240,613793) complement deca ( 444) 198 42.7 0.0052
>>NP_001461 (OMIM: 603540) gamma-aminobutyric acid type (961 aa)
initn: 6486 init1: 6486 opt: 6486 Z-score: 5430.9 bits: 1016.3 E(85289): 0
Smith-Waterman score: 6486; 100.0% identity (100.0% similar) in 961 aa overlap (1-961:1-961)
10 20 30 40 50 60
pF1KB8 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB8 IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
910 920 930 940 950 960
pF1KB8 K
:
NP_001 K
>>XP_005249039 (OMIM: 603540) PREDICTED: gamma-aminobuty (966 aa)
initn: 6486 init1: 6486 opt: 6486 Z-score: 5430.8 bits: 1016.3 E(85289): 0
Smith-Waterman score: 6486; 100.0% identity (100.0% similar) in 961 aa overlap (1-961:6-966)
10 20 30 40 50
pF1KB8 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPGAWMLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGAL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 LLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYG
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 YKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFA
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB8 FASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKEN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB8 RELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSR
910 920 930 940 950 960
960
pF1KB8 VHLLYK
::::::
XP_005 VHLLYK
>>NP_068704 (OMIM: 603540) gamma-aminobutyric acid type (899 aa)
initn: 5359 init1: 5359 opt: 5400 Z-score: 4522.7 bits: 848.2 E(85289): 0
Smith-Waterman score: 5905; 93.5% identity (93.5% similar) in 961 aa overlap (1-961:1-899)
10 20 30 40 50 60
pF1KB8 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP
:::::::::::::::::::::::::::::::::::::
NP_068 YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCV-----------------------
70 80 90
130 140 150 160 170 180
pF1KB8 ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG
:::::::::::::::::::::
NP_068 ---------------------------------------NRTPHSERRAVYIGALFPMSG
100 110
190 200 210 220 230 240
pF1KB8 GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB8 ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB8 FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB8 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB8 GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB8 LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB8 QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB8 LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB8 FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB8 DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB8 LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
720 730 740 750 760 770
850 860 870 880 890 900
pF1KB8 IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
780 790 800 810 820 830
910 920 930 940 950 960
pF1KB8 IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
840 850 860 870 880 890
pF1KB8 K
:
NP_068 K
>>XP_006715110 (OMIM: 603540) PREDICTED: gamma-aminobuty (904 aa)
initn: 5359 init1: 5359 opt: 5400 Z-score: 4522.7 bits: 848.2 E(85289): 0
Smith-Waterman score: 5905; 93.5% identity (93.5% similar) in 961 aa overlap (1-961:6-904)
10 20 30 40 50
pF1KB8 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPGAWMLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLT
::::::::::::::::::::::::::::::::::::::::::
XP_006 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCV------------------
70 80 90 100
120 130 140 150 160 170
pF1KB8 GGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGAL
::::::::::::::::
XP_006 --------------------------------------------NRTPHSERRAVYIGAL
110
180 190 200 210 220 230
pF1KB8 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB8 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB8 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB8 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
300 310 320 330 340 350
420 430 440 450 460 470
pF1KB8 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
360 370 380 390 400 410
480 490 500 510 520 530
pF1KB8 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
420 430 440 450 460 470
540 550 560 570 580 590
pF1KB8 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
480 490 500 510 520 530
600 610 620 630 640 650
pF1KB8 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
540 550 560 570 580 590
660 670 680 690 700 710
pF1KB8 RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVG
600 610 620 630 640 650
720 730 740 750 760 770
pF1KB8 LLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYG
660 670 680 690 700 710
780 790 800 810 820 830
pF1KB8 YKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFA
720 730 740 750 760 770
840 850 860 870 880 890
pF1KB8 FASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKEN
780 790 800 810 820 830
900 910 920 930 940 950
pF1KB8 RELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSR
840 850 860 870 880 890
960
pF1KB8 VHLLYK
::::::
XP_006 VHLLYK
900
>>NP_068703 (OMIM: 603540) gamma-aminobutyric acid type (844 aa)
initn: 5355 init1: 5355 opt: 5355 Z-score: 4485.5 bits: 841.2 E(85289): 0
Smith-Waterman score: 5355; 99.1% identity (99.4% similar) in 809 aa overlap (153-961:36-844)
130 140 150 160 170 180
pF1KB8 DGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSGGW
:.:: .: : ::::::::::::::::::
NP_068 PFARVGWPLPLLVVMAAGVAPVWASHSPHLPRPHSRVPPHPSSERRAVYIGALFPMSGGW
10 20 30 40 50 60
190 200 210 220 230 240
pF1KB8 PGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIIL
70 80 90 100 110 120
250 260 270 280 290 300
pF1KB8 MPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFE
130 140 150 160 170 180
310 320 330 340 350 360
pF1KB8 KWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARII
190 200 210 220 230 240
370 380 390 400 410 420
pF1KB8 VGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGH
250 260 270 280 290 300
430 440 450 460 470 480
pF1KB8 ITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALN
310 320 330 340 350 360
490 500 510 520 530 540
pF1KB8 KTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQL
370 380 390 400 410 420
550 560 570 580 590 600
pF1KB8 QGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLG
430 440 450 460 470 480
610 620 630 640 650 660
pF1KB8 IVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 IVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFV
490 500 510 520 530 540
670 680 690 700 710 720
pF1KB8 CQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDV
550 560 570 580 590 600
730 740 750 760 770 780
pF1KB8 LTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLL
610 620 630 640 650 660
790 800 810 820 830 840
pF1KB8 LGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIV
670 680 690 700 710 720
850 860 870 880 890 900
pF1KB8 FSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKII
730 740 750 760 770 780
910 920 930 940 950 960
pF1KB8 AEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
790 800 810 820 830 840
>>XP_011512755 (OMIM: 603540) PREDICTED: gamma-aminobuty (897 aa)
initn: 5310 init1: 5310 opt: 5340 Z-score: 4472.5 bits: 838.9 E(85289): 0
Smith-Waterman score: 5842; 92.8% identity (92.8% similar) in 961 aa overlap (1-961:6-897)
10 20 30 40 50
pF1KB8 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGAWMLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLT
:::::::::::::::::::::::::::::::::::::::::
XP_011 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRC-------------------
70 80 90 100
120 130 140 150 160 170
pF1KB8 GGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGAL
::::::::::
XP_011 --------------------------------------------------ERRAVYIGAL
110
180 190 200 210 220 230
pF1KB8 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB8 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB8 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB8 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
300 310 320 330 340 350
420 430 440 450 460 470
pF1KB8 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
360 370 380 390 400 410
480 490 500 510 520 530
pF1KB8 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
420 430 440 450 460 470
540 550 560 570 580 590
pF1KB8 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
480 490 500 510 520 530
600 610 620 630 640 650
pF1KB8 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
540 550 560 570 580 590
660 670 680 690 700 710
pF1KB8 RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVG
600 610 620 630 640 650
720 730 740 750 760 770
pF1KB8 LLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYG
660 670 680 690 700 710
780 790 800 810 820 830
pF1KB8 YKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFA
720 730 740 750 760 770
840 850 860 870 880 890
pF1KB8 FASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKEN
780 790 800 810 820 830
900 910 920 930 940 950
pF1KB8 RELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSR
840 850 860 870 880 890
960
pF1KB8 VHLLYK
::::::
XP_011 VHLLYK
>>NP_001305982 (OMIM: 603540) gamma-aminobutyric acid ty (784 aa)
initn: 5231 init1: 5231 opt: 5231 Z-score: 4382.2 bits: 822.0 E(85289): 0
Smith-Waterman score: 5231; 100.0% identity (100.0% similar) in 784 aa overlap (178-961:1-784)
150 160 170 180 190 200
pF1KB8 GQWSTPKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILP
::::::::::::::::::::::::::::::
NP_001 MSGGWPGGQACQPAVEMALEDVNSRRDILP
10 20 30
210 220 230 240 250 260
pF1KB8 DYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSY
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 GSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLE
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 ERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKK
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB8 YVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFV
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB8 EKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITD
280 290 300 310 320 330
510 520 530 540 550 560
pF1KB8 QIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDK
340 350 360 370 380 390
570 580 590 600 610 620
pF1KB8 WIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQP
400 410 420 430 440 450
630 640 650 660 670 680
pF1KB8 NLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWW
460 470 480 490 500 510
690 700 710 720 730 740
pF1KB8 VHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPK
520 530 540 550 560 570
750 760 770 780 790 800
pF1KB8 EDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGM
580 590 600 610 620 630
810 820 830 840 850 860
pF1KB8 AIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQ
640 650 660 670 680 690
870 880 890 900 910 920
pF1KB8 SEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRH
700 710 720 730 740 750
930 940 950 960
pF1KB8 PPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
::::::::::::::::::::::::::::::::::
NP_001 PPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
760 770 780
>>XP_016866165 (OMIM: 603540) PREDICTED: gamma-aminobuty (778 aa)
initn: 4932 init1: 4932 opt: 4936 Z-score: 4135.4 bits: 776.3 E(85289): 0
Smith-Waterman score: 4936; 99.5% identity (99.6% similar) in 747 aa overlap (215-961:32-778)
190 200 210 220 230 240
pF1KB8 GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMP
: . :::::::::::::::::::::::::
XP_016 RLSMCAGGSARWWGPRSASAWPTAPGQIWTHPAAVCDPGQATKYLYELLYNDPIKIILMP
10 20 30 40 50 60
250 260 270 280 290 300
pF1KB8 GCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKW
70 80 90 100 110 120
310 320 330 340 350 360
pF1KB8 GWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVG
130 140 150 160 170 180
370 380 390 400 410 420
pF1KB8 LFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHIT
190 200 210 220 230 240
430 440 450 460 470 480
pF1KB8 TEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKT
250 260 270 280 290 300
490 500 510 520 530 540
pF1KB8 SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQG
310 320 330 340 350 360
550 560 570 580 590 600
pF1KB8 GSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIV
370 380 390 400 410 420
610 620 630 640 650 660
pF1KB8 LAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQ
430 440 450 460 470 480
670 680 690 700 710 720
pF1KB8 ARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLT
490 500 510 520 530 540
730 740 750 760 770 780
pF1KB8 LAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLG
550 560 570 580 590 600
790 800 810 820 830 840
pF1KB8 IFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFS
610 620 630 640 650 660
850 860 870 880 890 900
pF1KB8 SYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAE
670 680 690 700 710 720
910 920 930 940 950 960
pF1KB8 KEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
730 740 750 760 770
>>XP_011512757 (OMIM: 603540) PREDICTED: gamma-aminobuty (680 aa)
initn: 4523 init1: 4523 opt: 4523 Z-score: 3790.7 bits: 712.3 E(85289): 2.1e-204
Smith-Waterman score: 4523; 99.4% identity (99.6% similar) in 670 aa overlap (1-670:6-675)
10 20 30 40 50
pF1KB8 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGAWMLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGAL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIW
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVG
::::::::: : :.
XP_011 RNQFPFVCQLSLTLVPVLSF
670 680
>>NP_005449 (OMIM: 188890,607340) gamma-aminobutyric aci (941 aa)
initn: 1412 init1: 477 opt: 1590 Z-score: 1335.0 bits: 258.4 E(85289): 1.3e-67
Smith-Waterman score: 1632; 35.1% identity (65.6% similar) in 793 aa overlap (150-917:42-817)
120 130 140 150 160 170
pF1KB8 PALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMS
:. : : : : .: :.:..
NP_005 PPPPPPPPPARLLLLLLLPLLLPLAPGAWGWARGAP-----RPPPSSPPLSIMG-LMPLT
20 30 40 50 60
180 190 200 210 220 230
pF1KB8 ---GGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYND
. :.. ::::.:.:.. .. . : : : : .:..:: ... : .:. .
NP_005 KEVAKGSIGRGVLPAVELAIEQIRNESLLRP-YFLDLRLYDTECDNAKGLKAFYDAIKYG
70 80 90 100 110 120
240 250 260 270 280 290
pF1KB8 PIKIILMPG-CSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNP
: ..... : : ::....::. . :::. ::.....:.:......: :::: :: . ::
NP_005 PNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNP
130 140 150 160 170 180
300 310 320 330 340 350
pF1KB8 TRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK
. .::.... ::...:. : .. :. . .:: . :::. .:: .:: . ::.::
NP_005 AILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLK
190 200 210 220 230 240
360 370 380 390 400 410
pF1KB8 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSIN---CTV
.:.:::.: : .. : :::: .:.: ..:.:: :.. ::: .:.. : :
NP_005 GNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCLR
250 260 270 280 290 300
420 430 440 450 460 470
pF1KB8 DEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLT-KRLKRHPEETGGFQEAPLAY
.. :.::.: ... :. . ..::. : :.. .. . :: : . :. ::
NP_005 KNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGY-----AY
310 320 330 340 350
480 490 500 510 520
pF1KB8 DAIWALALALNK---TSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFD
:.::..: .:.. : ...: :..::::...:. : ::: ..: ::.:.:::
NP_005 DGIWVIAKTLQRAMETLHASSRHQ-RIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFR
360 370 380 390 400 410
530 540 550 560 570 580
pF1KB8 ASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSW-SKTDKWIGGSPPADQTLVIKTFRFL
.: ::. . :.: . :.: :... : : . : .. :. :: :.:.... .: .
NP_005 -NGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKI
420 430 440 450 460 470
590 600 610 620 630 640
pF1KB8 SQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPL
: :. .:.:. ::...: . : ::: : . . :. :.: .::: .: :. :..: .
NP_005 SLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLF
480 490 500 510 520 530
650 660 670 680 690 700
pF1KB8 GLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEP
:::: .... : .: .: :.: .:.. ..:.::.: : ::..: . . :: : ..
NP_005 GLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKK---KIIKD
540 550 560 570 580 590
710 720 730 740 750 760
pF1KB8 WKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMN
:: . :: .. .:. : :: ::::.::.: .. : :.:: : :::: . .:.
NP_005 QKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMT
600 610 620 630 640 650
770 780 790 800 810 820
pF1KB8 TWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILS
:::: :.:::::.:.: :::.::..:: .:: . .::..:::...:.: : :...
NP_005 IWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTR
660 670 680 690 700 710
830 840 850 860 870
pF1KB8 SQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEW----------QSEAQDTMKTG
.: .. : ...:.:.: : ::: ..::::. : : . :.. .. ::.
NP_005 DQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTS
720 730 740 750 760 770
880 890 900 910 920 930
pF1KB8 SS-TNNNEEEKSRL--LEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEP
.: :. :. ::: :..::..:. :.: .. . :. :::
NP_005 TSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQEL
780 790 800 810 820 830
940 950 960
pF1KB8 SGGLPRGPPEPPDRLSCDGSRVHLLYK
NP_005 NDILNLGNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSL
840 850 860 870 880 890
961 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:34:52 2016 done: Sat Nov 5 16:34:54 2016
Total Scan time: 13.570 Total Display time: 0.380
Function used was FASTA [36.3.4 Apr, 2011]