FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8444, 303 aa
  1>>>pF1KB8444 303 - 303 aa - 303 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2598+/-0.000411; mu= 3.7877+/- 0.025
 mean_var=308.5148+/-71.469, 0's: 0 Z-trim(119.6): 72  B-trim: 39 in 1/57
 Lambda= 0.073019
 statistics sampled from 33659 (33757) to 33659 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.396), width:  16
 Scan time:  7.940

The best scores are:                                      opt bits E(85289)
NP_005198 (OMIM: 602007) crk-like protein [Homo sa ( 303) 2078 232.2 9.9e-61
NP_058431 (OMIM: 164762) adapter molecule crk isof ( 304)  642 80.9 3.4e-15
NP_005197 (OMIM: 164762) adapter molecule crk isof ( 204)  321 46.9 4.1e-05


>>NP_005198 (OMIM: 602007) crk-like protein [Homo sapien  (303 aa)
 initn: 2078 init1: 2078 opt: 2078  Z-score: 1211.3  bits: 232.2 E(85289): 9.9e-61
Smith-Waterman score: 2078; 100.0% identity (100.0% similar) in 303 aa overlap (1-303:1-303)

               10        20        30        40        50        60
pF1KB8 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD
              250       260       270       280       290       300

          
pF1KB8 ENE
       :::
NP_005 ENE
          

>>NP_058431 (OMIM: 164762) adapter molecule crk isoform   (304 aa)
 initn: 1223 init1: 403 opt: 642  Z-score: 393.7  bits: 80.9 E(85289): 3.4e-15
Smith-Waterman score: 1135; 57.5% identity (73.8% similar) in 320 aa overlap (6-302:5-302)

               10        20        30        40        50        60
pF1KB8 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH
            ::: .::.:: : .::::: . :::::::.:::::::: ::::::::::::::::
NP_058  MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSH
                10        20        30        40        50         

                                70        80        90       100   
pF1KB8 YIINSLPNR-----------------RFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAP
       :::::   :                 :..::::::: :::::::::::::::::::::. 
NP_058 YIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVS
      60        70        80        90       100       110         

           110       120       130       140       150       160   
pF1KB8 RYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA
       :       : .. ..   ... ::::.:.:: ::: ::::::::.:: : .:::::::.:
NP_058 R-------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNA
     120              130       140       150       160       170  

           170       180             190       200       210       
pF1KB8 RNKDGRVGMIPVPYVEKLVRSSPH------GKHGNRNSNSYGIPEPAHAYAQPQTTTPLP
       ....:. ::::::::::   .:        :.. . . .  : :::.  ::::...    
NP_058 EDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPG-PYAQPSVN----
            180       190       200       210        220           

       220       230       240       250       260       270       
pF1KB8 AVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEG
                 ::::. ::::..:..:::::: ::::::::::::..::::..:..:::::
NP_058 ----------TPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEG
                 230       240       250       260       270       

       280       290       300    
pF1KB8 EVNGRKGLFPFTHVKIFDPQNPDENE 
       : ::..: ::::::...: :::::.  
NP_058 ECNGKRGHFPFTHVRLLDQQNPDEDFS
       280       290       300    

>>NP_005197 (OMIM: 164762) adapter molecule crk isoform   (204 aa)
 initn: 778 init1: 321 opt: 321  Z-score: 212.8  bits: 46.9 E(85289): 4.1e-05
Smith-Waterman score: 745; 63.0% identity (76.0% similar) in 192 aa overlap (6-180:5-189)

               10        20        30        40        50        60
pF1KB8 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH
            ::: .::.:: : .::::: . :::::::.:::::::: ::::::::::::::::
NP_005  MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSH
                10        20        30        40        50         

                                70        80        90       100   
pF1KB8 YIINSLPNR-----------------RFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAP
       :::::   :                 :..::::::: :::::::::::::::::::::. 
NP_005 YIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVS
      60        70        80        90       100       110         

           110       120       130       140       150       160   
pF1KB8 RYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA
       :       : .. ..   ... ::::.:.:: ::: ::::::::.:: : .:::::::.:
NP_005 R-------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNA
     120              130       140       150       160       170  

           170       180       190       200       210       220   
pF1KB8 RNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSP
       ....:. ::::::::::                                           
NP_005 EDSEGKRGMIPVPYVEKYRPASASVSALIGGR                            
            180       190       200                                




303 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:56:10 2016 done: Fri Nov  4 12:56:11 2016
 Total Scan time:  7.940 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]