Result of FASTA (omim) for
pF1KB8429
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8429, 435 aa
1>>>pF1KB8429 435 - 435 aa - 435 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.2649+/-0.000645; mu= -12.4027+/- 0.038
mean_var=709.8654+/-158.420, 0's: 0 Z-trim(114.1): 869 B-trim: 0 in 0/55
Lambda= 0.048138
statistics sampled from 22733 (23841) to 22733 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.28), width: 16
Scan time: 8.710
The best scores are: opt bits E(85289)
NP_001269476 (OMIM: 609437) serine/threonine-prote ( 435) 2868 215.5 2.2e-55
NP_114406 (OMIM: 609437) serine/threonine-protein ( 435) 2868 215.5 2.2e-55
NP_001269475 (OMIM: 609437) serine/threonine-prote ( 440) 2848 214.1 5.8e-55
NP_079471 (OMIM: 609461) tribbles homolog 1 isofor ( 372) 421 45.4 0.00029
NP_001269914 (OMIM: 609461) tribbles homolog 1 iso ( 206) 409 44.2 0.00037
NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo ( 343) 397 43.7 0.00088
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661) 391 43.7 0.0017
XP_016857181 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 382 42.9 0.0021
XP_016857182 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 382 42.9 0.0021
XP_016857183 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 382 42.9 0.0021
NP_006243 (OMIM: 600497) 5'-AMP-activated protein ( 552) 382 43.0 0.0023
NP_066981 (OMIM: 607898) tribbles homolog 3 isofor ( 358) 373 42.1 0.0028
NP_001288122 (OMIM: 607898) tribbles homolog 3 iso ( 358) 373 42.1 0.0028
NP_001288117 (OMIM: 607898) tribbles homolog 3 iso ( 358) 373 42.1 0.0028
NP_001288125 (OMIM: 607898) tribbles homolog 3 iso ( 358) 373 42.1 0.0028
NP_001288119 (OMIM: 607898) tribbles homolog 3 iso ( 358) 373 42.1 0.0028
NP_001288130 (OMIM: 607898) tribbles homolog 3 iso ( 385) 373 42.1 0.003
XP_016883478 (OMIM: 607898) PREDICTED: tribbles ho ( 385) 373 42.1 0.003
NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 369 41.9 0.0038
NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 369 41.9 0.0038
NP_001617 (OMIM: 125853,164731,240900) RAC-beta se ( 481) 369 42.0 0.0041
XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 369 42.0 0.0041
XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 369 42.0 0.0041
XP_011524920 (OMIM: 125853,164731,240900) PREDICTE ( 481) 369 42.0 0.0041
XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 369 42.0 0.0041
XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 369 42.0 0.0041
XP_011524917 (OMIM: 125853,164731,240900) PREDICTE ( 481) 369 42.0 0.0041
XP_011524918 (OMIM: 125853,164731,240900) PREDICTE ( 481) 369 42.0 0.0041
XP_016865114 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 533) 370 42.1 0.0041
NP_006242 (OMIM: 602739) 5'-AMP-activated protein ( 559) 370 42.2 0.0042
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373) 355 40.9 0.0069
XP_016865113 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 548) 355 41.1 0.0085
XP_011516387 (OMIM: 607025) PREDICTED: maternal em ( 568) 355 41.1 0.0087
NP_996790 (OMIM: 602739) 5'-AMP-activated protein ( 574) 355 41.1 0.0087
NP_001243619 (OMIM: 607025) maternal embryonic leu ( 580) 355 41.2 0.0088
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610) 355 41.2 0.009
NP_001243618 (OMIM: 607025) maternal embryonic leu ( 619) 355 41.2 0.0091
XP_011516383 (OMIM: 607025) PREDICTED: maternal em ( 619) 355 41.2 0.0091
XP_011516385 (OMIM: 607025) PREDICTED: maternal em ( 619) 355 41.2 0.0091
XP_011516384 (OMIM: 607025) PREDICTED: maternal em ( 619) 355 41.2 0.0091
XP_011516386 (OMIM: 607025) PREDICTED: maternal em ( 619) 355 41.2 0.0091
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651) 355 41.2 0.0094
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651) 355 41.2 0.0094
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651) 355 41.2 0.0094
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651) 355 41.2 0.0094
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651) 355 41.2 0.0094
NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 350 40.7 0.0099
NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 350 40.7 0.0099
>>NP_001269476 (OMIM: 609437) serine/threonine-protein k (435 aa)
initn: 2868 init1: 2868 opt: 2868 Z-score: 1115.3 bits: 215.5 E(85289): 2.2e-55
Smith-Waterman score: 2868; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KB8 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPM
370 380 390 400 410 420
430
pF1KB8 TSLDTAILAQRYLRK
:::::::::::::::
NP_001 TSLDTAILAQRYLRK
430
>>NP_114406 (OMIM: 609437) serine/threonine-protein kina (435 aa)
initn: 2868 init1: 2868 opt: 2868 Z-score: 1115.3 bits: 215.5 E(85289): 2.2e-55
Smith-Waterman score: 2868; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KB8 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 DFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 ENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPM
370 380 390 400 410 420
430
pF1KB8 TSLDTAILAQRYLRK
:::::::::::::::
NP_114 TSLDTAILAQRYLRK
430
>>NP_001269475 (OMIM: 609437) serine/threonine-protein k (440 aa)
initn: 2635 init1: 2635 opt: 2848 Z-score: 1107.8 bits: 214.1 E(85289): 5.8e-55
Smith-Waterman score: 2848; 98.9% identity (98.9% similar) in 440 aa overlap (1-435:1-440)
10 20 30 40 50
pF1KB8 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFIL-----GPRLGNSPVPSIVQCLAR
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_001 MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILALCAVGPRLGNSPVPSIVQCLAR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 KDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 RTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 VIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 SPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 DGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 SNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGH
370 380 390 400 410 420
420 430
pF1KB8 DAQPMTSLDTAILAQRYLRK
::::::::::::::::::::
NP_001 DAQPMTSLDTAILAQRYLRK
430 440
>>NP_079471 (OMIM: 609461) tribbles homolog 1 isoform 1 (372 aa)
initn: 322 init1: 187 opt: 421 Z-score: 197.6 bits: 45.4 E(85289): 0.00029
Smith-Waterman score: 421; 34.4% identity (66.5% similar) in 221 aa overlap (137-353:147-363)
110 120 130 140 150 160
pF1KB8 VHHHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKE
. ..: :. : .: :. ... :: ..
NP_079 LRCKVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEK--DFGDMHSYVRSR
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 KRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVS-
::: :.:.. .: ..: .: ::. :: :::: ..:.. . . . :...
NP_079 KRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 EGDLLKDQRGSPAYISPDVLSGR-PYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFR
: : :.:..: :::.::..:. : :: .:.:.:::.:.:.: :..::.:: :. ::
NP_079 EDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 KIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVL--EALSAIIASWQSLSSLS
::. ... ::: ..: .. ::::.:: .:..::.: ..: . ... : ..
NP_079 KIRRGQFCIPE--HISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIG
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB8 GPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKR
:.::. ..
NP_079 TSDQIVPEYQEDSDISSFFC
360 370
>>NP_001269914 (OMIM: 609461) tribbles homolog 1 isoform (206 aa)
initn: 315 init1: 187 opt: 409 Z-score: 195.6 bits: 44.2 E(85289): 0.00037
Smith-Waterman score: 409; 35.7% identity (67.8% similar) in 199 aa overlap (159-353:1-197)
130 140 150 160 170 180
pF1KB8 MVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEAL
.. :: ..::: :.:.. .: ..: .:
NP_001 MHSYVRSRKRLREEEAARLFKQIVSAVAHC
10 20 30
190 200 210 220 230 240
pF1KB8 HQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVS-EGDLLKDQRGSPAYISPDVLSG
::. :: :::: ..:.. . . . :... : : :.:..: :::.::..:.
NP_001 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB8 R-PYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCL
: :: .:.:.:::.:.:.: :..::.:: :. :: ::. ... ::: ..: .. ::
NP_001 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPE--HISPKARCL
100 110 120 130 140
310 320 330 340 350 360
pF1KB8 IRKLLVLDPQQRLAAADVL--EALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEA
::.:: .:..::.: ..: . ... : .. :.::. ..
NP_001 IRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
150 160 170 180 190 200
370 380 390 400 410 420
pF1KB8 KVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLD
>>NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo sapi (343 aa)
initn: 330 init1: 184 opt: 397 Z-score: 188.9 bits: 43.7 E(85289): 0.00088
Smith-Waterman score: 397; 31.8% identity (67.7% similar) in 220 aa overlap (139-355:119-328)
110 120 130 140 150 160
pF1KB8 HHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKR
..: :. : ... ... .: :.
NP_067 CKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYG--DMHSFVRTCKK
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB8 LSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVL-NKRTHRITITNFCLGKHLVSEG
: :.:.. .::... .: :. ..: ::::: .... ... :. . .. . : ..
NP_067 LREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDD
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB8 DLLKDQRGSPAYISPDVL-SGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKI
: :.:..: :::.::..: .. : :: .:.:.:::.:.::: :..::.: :. :: ::
NP_067 DSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKI
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB8 KAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLS-SLSGPL
. ....::: .: .. ::::..: .:..::.. ..:. : : . :.:.
NP_067 RRGQFNIPET--LSPKAKCLIRSILRREPSERLTSQEILDH------PWFSTDFSVSNSA
270 280 290 300 310
350 360 370 380 390 400
pF1KB8 QVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFG
. ...::.
NP_067 YGAKEVSDQLVPDVNMEENLDPFFN
320 330 340
>>NP_055655 (OMIM: 608130) NUAK family SNF1-like kinase (661 aa)
initn: 342 init1: 214 opt: 391 Z-score: 183.9 bits: 43.7 E(85289): 0.0017
Smith-Waterman score: 391; 40.2% identity (69.8% similar) in 169 aa overlap (159-324:140-300)
130 140 150 160 170 180
pF1KB8 MVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEAL
: :. ...::::::: .: ..: .:.
NP_055 LNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYC
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 HQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGR
:....::::::: :..:. . : :..: :. .: .. .:. ::: : ::....::
NP_055 HKNGVVHRDLKLENILLDDNCN-IKIADFGLS-NLYQKDKFLQTFCGSPLYASPEIVNGR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 PYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEY---TIPEDGRVSENTVC
:::: : :::::.:.:..:: .:: ..:.:.:...:: : : :.:
NP_055 PYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDAR------G
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 LIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAK
::: .:...:..: . :.
NP_055 LIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGL
290 300 310 320 330 340
>>XP_016857181 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 312 init1: 201 opt: 382 Z-score: 182.0 bits: 42.9 E(85289): 0.0021
Smith-Waterman score: 382; 30.5% identity (60.5% similar) in 256 aa overlap (162-409:14-257)
140 150 160 170 180 190
pF1KB8 KMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQK
:. :. :. : :. .: ... .:. :..
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRH
10 20 30 40
200 210 220 230 240 250
pF1KB8 NIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYR
.:::::: :..:. . . :..: :. ...:.:..:. . ::: : .:.:.::: :
XP_016 MVVHRDLKPENVLLDAHMN-AKIADFGLS-NMMSDGEFLRTSCGSPNYAAPEVISGRLYA
50 60 70 80 90 100
260 270 280 290 300 310
pF1KB8 GKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLL
: :.:. ::.:...: : .:: : ::.::... . ::: ...... :. ..:
XP_016 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE--YLNRSVATLLMHML
110 120 130 140 150
320 330 340 350 360
pF1KB8 VLDPQQRLAAADVLEALSAIIASW--QSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEE
.:: .: . :. : : :.: : : . :. : .. . .. .:. :
XP_016 QVDPLKRATIKDIREH------EWFKQDLPSYLFPED--PSYDANVIDDEAVKEVCEKFE
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB8 CSQYEFENYMRQ---QLLLAEEKSSIHDAR---SWVPKRQFGSAPPVRRLGHDAQPMTSL
:.. : : . . : :: : : : . . . ..:.::
XP_016 CTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPP
220 230 240 250 260 270
430
pF1KB8 DTAILAQRYLRK
XP_016 GLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYR
280 290 300 310 320 330
>>XP_016857182 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 312 init1: 201 opt: 382 Z-score: 182.0 bits: 42.9 E(85289): 0.0021
Smith-Waterman score: 382; 30.5% identity (60.5% similar) in 256 aa overlap (162-409:14-257)
140 150 160 170 180 190
pF1KB8 KMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQK
:. :. :. : :. .: ... .:. :..
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRH
10 20 30 40
200 210 220 230 240 250
pF1KB8 NIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYR
.:::::: :..:. . . :..: :. ...:.:..:. . ::: : .:.:.::: :
XP_016 MVVHRDLKPENVLLDAHMN-AKIADFGLS-NMMSDGEFLRTSCGSPNYAAPEVISGRLYA
50 60 70 80 90 100
260 270 280 290 300 310
pF1KB8 GKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLL
: :.:. ::.:...: : .:: : ::.::... . ::: ...... :. ..:
XP_016 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE--YLNRSVATLLMHML
110 120 130 140 150
320 330 340 350 360
pF1KB8 VLDPQQRLAAADVLEALSAIIASW--QSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEE
.:: .: . :. : : :.: : : . :. : .. . .. .:. :
XP_016 QVDPLKRATIKDIREH------EWFKQDLPSYLFPED--PSYDANVIDDEAVKEVCEKFE
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB8 CSQYEFENYMRQ---QLLLAEEKSSIHDAR---SWVPKRQFGSAPPVRRLGHDAQPMTSL
:.. : : . . : :: : : : . . . ..:.::
XP_016 CTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPP
220 230 240 250 260 270
430
pF1KB8 DTAILAQRYLRK
XP_016 GLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYR
280 290 300 310 320 330
>>XP_016857183 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 312 init1: 201 opt: 382 Z-score: 182.0 bits: 42.9 E(85289): 0.0021
Smith-Waterman score: 382; 30.5% identity (60.5% similar) in 256 aa overlap (162-409:14-257)
140 150 160 170 180 190
pF1KB8 KMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQK
:. :. :. : :. .: ... .:. :..
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRH
10 20 30 40
200 210 220 230 240 250
pF1KB8 NIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYR
.:::::: :..:. . . :..: :. ...:.:..:. . ::: : .:.:.::: :
XP_016 MVVHRDLKPENVLLDAHMN-AKIADFGLS-NMMSDGEFLRTSCGSPNYAAPEVISGRLYA
50 60 70 80 90 100
260 270 280 290 300 310
pF1KB8 GKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLL
: :.:. ::.:...: : .:: : ::.::... . ::: ...... :. ..:
XP_016 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE--YLNRSVATLLMHML
110 120 130 140 150
320 330 340 350 360
pF1KB8 VLDPQQRLAAADVLEALSAIIASW--QSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEE
.:: .: . :. : : :.: : : . :. : .. . .. .:. :
XP_016 QVDPLKRATIKDIREH------EWFKQDLPSYLFPED--PSYDANVIDDEAVKEVCEKFE
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB8 CSQYEFENYMRQ---QLLLAEEKSSIHDAR---SWVPKRQFGSAPPVRRLGHDAQPMTSL
:.. : : . . : :: : : : . . . ..:.::
XP_016 CTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPP
220 230 240 250 260 270
430
pF1KB8 DTAILAQRYLRK
XP_016 GLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYR
280 290 300 310 320 330
435 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:50:18 2016 done: Fri Nov 4 12:50:20 2016
Total Scan time: 8.710 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]