Result of FASTA (ccds) for
pF1KB8368
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8368, 622 aa
1>>>pF1KB8368 622 - 622 aa - 622 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7817+/-0.000818; mu= 12.3937+/- 0.049
mean_var=103.6706+/-20.429, 0's: 0 Z-trim(110.2): 61 B-trim: 5 in 2/52
Lambda= 0.125964
statistics sampled from 11370 (11431) to 11370 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.351), width: 16
Scan time: 3.700
The best scores are: opt bits E(32554)
CCDS3909.1 PRLR gene_id:5618|Hs108|chr5 ( 622) 4336 798.7 0
CCDS56358.1 PRLR gene_id:5618|Hs108|chr5 ( 521) 3459 639.3 3.8e-183
CCDS56361.1 PRLR gene_id:5618|Hs108|chr5 ( 376) 2367 440.8 1.6e-123
CCDS56362.1 PRLR gene_id:5618|Hs108|chr5 ( 349) 2358 439.1 4.6e-123
CCDS56360.1 PRLR gene_id:5618|Hs108|chr5 ( 288) 2014 376.6 2.6e-104
CCDS56359.1 PRLR gene_id:5618|Hs108|chr5 ( 268) 1628 306.4 3.2e-83
CCDS56364.1 GHR gene_id:2690|Hs108|chr5 ( 616) 532 107.4 5.8e-23
CCDS3940.1 GHR gene_id:2690|Hs108|chr5 ( 638) 529 106.9 8.8e-23
CCDS75239.1 GHR gene_id:2690|Hs108|chr5 ( 645) 529 106.9 8.8e-23
CCDS32962.1 CRLF1 gene_id:9244|Hs108|chr19 ( 422) 448 92.1 1.7e-18
CCDS75240.1 GHR gene_id:2690|Hs108|chr5 ( 295) 378 79.3 8.3e-15
>>CCDS3909.1 PRLR gene_id:5618|Hs108|chr5 (622 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 4261.7 bits: 798.7 E(32554): 0
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 622 aa overlap (1-622:1-622)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
550 560 570 580 590 600
610 620
pF1KB8 KCRLQLGGLDYLDPACFTHSFH
::::::::::::::::::::::
CCDS39 KCRLQLGGLDYLDPACFTHSFH
610 620
>>CCDS56358.1 PRLR gene_id:5618|Hs108|chr5 (521 aa)
initn: 3456 init1: 3456 opt: 3459 Z-score: 3401.5 bits: 639.3 E(32554): 3.8e-183
Smith-Waterman score: 3459; 97.8% identity (99.0% similar) in 511 aa overlap (113-622:11-521)
90 100 110 120 130 140
pF1KB8 PNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYI-VQPDPPLELAVEVKQPE
:. :.... . :::::::::::::::::
CCDS56 MKENVASATVFTLLLFLNTCLLNVQPDPPLELAVEVKQPE
10 20 30 40
150 160 170 180 190 200
pF1KB8 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQK
50 60 70 80 90 100
210 220 230 240 250 260
pF1KB8 YLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 YLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGY
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB8 SMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSE
170 180 190 200 210 220
330 340 350 360 370 380
pF1KB8 DQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIE
230 240 250 260 270 280
390 400 410 420 430 440
pF1KB8 KPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAV
290 300 310 320 330 340
450 460 470 480 490 500
pF1KB8 GPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPF
350 360 370 380 390 400
510 520 530 540 550 560
pF1KB8 GSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLV
410 420 430 440 450 460
570 580 590 600 610 620
pF1KB8 PDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSF
470 480 490 500 510 520
pF1KB8 H
:
CCDS56 H
>>CCDS56361.1 PRLR gene_id:5618|Hs108|chr5 (376 aa)
initn: 2366 init1: 2366 opt: 2367 Z-score: 2331.2 bits: 440.8 E(32554): 1.6e-123
Smith-Waterman score: 2367; 98.8% identity (99.1% similar) in 343 aa overlap (1-343:1-342)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::: : .:
CCDS56 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQG-DPLMLGASHYKNLKSYRPRKIS
310 320 330 340 350
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
CCDS56 SQGRLAVFTKATLTTVQ
360 370
>>CCDS56362.1 PRLR gene_id:5618|Hs108|chr5 (349 aa)
initn: 2358 init1: 2358 opt: 2358 Z-score: 2322.9 bits: 439.1 E(32554): 4.6e-123
Smith-Waterman score: 2358; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::
CCDS56 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQEREQRQAQEARDS
310 320 330 340
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
>>CCDS56360.1 PRLR gene_id:5618|Hs108|chr5 (288 aa)
initn: 2014 init1: 2014 opt: 2014 Z-score: 1986.3 bits: 376.6 E(32554): 2.6e-104
Smith-Waterman score: 2014; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
:::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEVTP
250 260 270 280
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
>>CCDS56359.1 PRLR gene_id:5618|Hs108|chr5 (268 aa)
initn: 1628 init1: 1628 opt: 1628 Z-score: 1607.7 bits: 306.4 E(32554): 3.2e-83
Smith-Waterman score: 1628; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSGDPLMLGASHYK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
CCDS56 NLKSYRPRKISSQGRLAVFTKATLTTVQ
250 260
>>CCDS56364.1 GHR gene_id:2690|Hs108|chr5 (616 aa)
initn: 470 init1: 124 opt: 532 Z-score: 525.7 bits: 107.4 E(32554): 5.8e-23
Smith-Waterman score: 591; 27.4% identity (52.3% similar) in 621 aa overlap (10-601:7-556)
10 20 30 40 50
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGK-PEIFKCRSPNKETFTCWWRP----GTD--
..:: : .. ..:. .: :.. :::::..:::.: : ::
CCDS56 MDLWQLLLTLALAGSSDAFSGSEDSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS56 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPY--CIKLTSNGGTV-
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS56 -DEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIP--S
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .: :
CCDS56 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 DFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVTCIFPPVPGPKIKGFDAHLL
.:: .. :. . ... .. : .. : : : . :.:::: :::::.: ::
CCDS56 QFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLL
240 250 260 270 280 290
290 300 310 320 330
pF1KB8 EKGKSEELLSALGCQD-FPPTSDYEDLLVEYLEVDDSE----------DQHLMSVHSKEH
..:: ::. . :. .: . : .: ::..:.: .: :. : : : : :
CCDS56 KEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSH
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB8 PSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTWD
. :.: : :::: :: :: :. . : .. : :... .
CCDS56 SNLGVK------DGDSGRTSC---------CE-PDILETDFNANDIHEG-----TSEVAQ
360 370 380 390
400 410 420 430 440 450
pF1KB8 PQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGA-PATLLN
:: ..:. . : : : .:.: : :: :.: :: :...
CCDS56 PQ--RLKGEADLL------C----LDQKNQNN--SPYH---DAC-----PATQQPSVIQA
400 410 420
460 470 480 490 500 510
pF1KB8 EAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLD-YVE
: .: : . . :: .:: :. . : ..: .: . .: :..
CCDS56 EKNKP-----QPLPT--EG-------AESTHQAAHI-------QLSNP-SSLSNIDFYAQ
430 440 450 460
520 530 540 550 560 570
pF1KB8 IHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHAKNVAC
. .. :.. : : :....: . :: . . . .::: . . . ::
CCDS56 VSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVS-LCQENFLMDNAYFCEADAKKCIPVAP
470 480 490 500 510 520
580 590 600 610 620
pF1KB8 FEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH
. .. :::.:.. . ..:.....
CCDS56 HIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHIVQSPQGLI
530 540 550 560 570 580
>>CCDS3940.1 GHR gene_id:2690|Hs108|chr5 (638 aa)
initn: 470 init1: 124 opt: 529 Z-score: 522.5 bits: 106.9 E(32554): 8.8e-23
Smith-Waterman score: 588; 27.5% identity (52.2% similar) in 600 aa overlap (30-601:50-578)
10 20 30 40 50
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRP----GTD--
.:.. :::::..:::.: : ::
CCDS39 SGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB8 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS39 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYC--IKLTSNGGT--
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB8 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS39 VDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
140 150 160 170 180 190
180 190 200 210 220
pF1KB8 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIP--S
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .: :
CCDS39 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 DFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVTCIFPPVPGPKIKGFDAHLL
.:: .. :. . ... .. : .. : : : . :.:::: :::::.: ::
CCDS39 QFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLL
260 270 280 290 300 310
290 300 310 320 330
pF1KB8 EKGKSEELLSALGCQD-FPPTSDYEDLLVEYLEVDDSE----------DQHLMSVHSKEH
..:: ::. . :. .: . : .: ::..:.: .: :. : : : : :
CCDS39 KEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSH
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB8 PSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTWD
. :.: : :::: :: :: :. . : .. : :... .
CCDS39 SNLGVK------DGDSGRTSC---------CE-PDILETDFNANDIHEG-----TSEVAQ
380 390 400 410
400 410 420 430 440 450
pF1KB8 PQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGA-PATLLN
:: ..:. . : : : .:.: : :: :.: :: :...
CCDS39 PQ--RLKGEADLL------C----LDQKNQNN--SPYH---DAC-----PATQQPSVIQA
420 430 440 450
460 470 480 490 500 510
pF1KB8 EAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLD-YVE
: .: : . . :: .:: :. . : ..: .: . .: :..
CCDS39 EKNKP-----QPLPT--EG-------AESTHQAAH-------IQLSNP-SSLSNIDFYAQ
460 470 480
520 530 540 550 560 570
pF1KB8 IHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHAKNVAC
. .. :.. : : :....: . :: . . . .::: . . . ::
CCDS39 VSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVS-LCQENFLMDNAYFCEADAKKCIPVAP
490 500 510 520 530 540
580 590 600 610 620
pF1KB8 FEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH
. .. :::.:.. . ..:.....
CCDS39 HIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHIVQSPQGLI
550 560 570 580 590 600
>>CCDS75239.1 GHR gene_id:2690|Hs108|chr5 (645 aa)
initn: 470 init1: 124 opt: 529 Z-score: 522.4 bits: 106.9 E(32554): 8.8e-23
Smith-Waterman score: 588; 27.5% identity (52.2% similar) in 600 aa overlap (30-601:57-585)
10 20 30 40 50
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRP----GTD--
.:.. :::::..:::.: : ::
CCDS75 SGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB8 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS75 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYC--IKLTSNGGT--
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB8 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS75 VDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
150 160 170 180 190 200
180 190 200 210 220
pF1KB8 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIP--S
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .: :
CCDS75 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB8 DFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVTCIFPPVPGPKIKGFDAHLL
.:: .. :. . ... .. : .. : : : . :.:::: :::::.: ::
CCDS75 QFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLL
270 280 290 300 310 320
290 300 310 320 330
pF1KB8 EKGKSEELLSALGCQD-FPPTSDYEDLLVEYLEVDDSE----------DQHLMSVHSKEH
..:: ::. . :. .: . : .: ::..:.: .: :. : : : : :
CCDS75 KEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSH
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB8 PSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTWD
. :.: : :::: :: :: :. . : .. : :... .
CCDS75 SNLGVK------DGDSGRTSC---------CE-PDILETDFNANDIHEG-----TSEVAQ
390 400 410 420
400 410 420 430 440 450
pF1KB8 PQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGA-PATLLN
:: ..:. . : : : .:.: : :: :.: :: :...
CCDS75 PQ--RLKGEADLL------C----LDQKNQNN--SPYH---DAC-----PATQQPSVIQA
430 440 450
460 470 480 490 500 510
pF1KB8 EAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLD-YVE
: .: : . . :: .:: :. . : ..: .: . .: :..
CCDS75 EKNKP-----QPLPT--EG-------AESTHQAAH-------IQLSNP-SSLSNIDFYAQ
460 470 480 490
520 530 540 550 560 570
pF1KB8 IHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHAKNVAC
. .. :.. : : :....: . :: . . . .::: . . . ::
CCDS75 VSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVS-LCQENFLMDNAYFCEADAKKCIPVAP
500 510 520 530 540 550
580 590 600 610 620
pF1KB8 FEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH
. .. :::.:.. . ..:.....
CCDS75 HIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHIVQSPQGLI
560 570 580 590 600 610
>>CCDS32962.1 CRLF1 gene_id:9244|Hs108|chr19 (422 aa)
initn: 363 init1: 106 opt: 448 Z-score: 445.7 bits: 92.1 E(32554): 1.7e-18
Smith-Waterman score: 448; 37.1% identity (59.8% similar) in 224 aa overlap (15-227:123-339)
10 20 30 40
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETF
.. ..:: : ::: :: ..: : : . .
CCDS32 ASTLALALANLNGSRQRSGDNLVCHARDGSILAGSCLYVG-LPPEKPVNISCWSKNMKDL
100 110 120 130 140 150
50 60 70 80 90 100
pF1KB8 TCWWRPGTDGG--LPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMM
:: : ::. : : ::::: :. . . : .: : ::.:::. :. ... : .
CCDS32 TCRWTPGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDL-ALFTPYEIW
160 170 180 190 200 210
110 120 130 140 150 160
pF1KB8 VNATNQMGSSFSDELYVDVTYIVQPDPPLELAV-EVKQPEDRKPYLWIKWSPPTLIDLKT
:.:::..::. :: : .:. .: ::: .. : .: ::. :. :::.: :.
CCDS32 VEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWV--SPPALKDF--
220 230 240 250 260
170 180 190 200 210
pF1KB8 GWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQKYLVQVRCKP-------DHG
: :.:: . : ...:.. ...:: .. .:.:: :.:::::.: :
CCDS32 -LFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAG
270 280 290 300 310 320
220 230 240 250 260 270
pF1KB8 YWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPG
:: :: : . :
CCDS32 IWSEWSHPTAASTPRSERPGPGGGACEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSF
330 340 350 360 370 380
622 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:18:34 2016 done: Fri Nov 4 12:18:35 2016
Total Scan time: 3.700 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]