Result of FASTA (omim) for
pF1KB8327
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8327, 254 aa
1>>>pF1KB8327 254 - 254 aa - 254 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3093+/-0.000356; mu= 14.0113+/- 0.022
mean_var=63.3963+/-12.490, 0's: 0 Z-trim(114.3): 36 B-trim: 0 in 0/48
Lambda= 0.161080
statistics sampled from 24014 (24044) to 24014 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.282), width: 16
Scan time: 5.590
The best scores are: opt bits E(85289)
NP_055112 (OMIM: 602473,608451) persulfide dioxyge ( 254) 1713 406.6 2.1e-113
XP_005258744 (OMIM: 602473,608451) PREDICTED: pers ( 227) 1545 367.6 1.1e-101
NP_001307796 (OMIM: 602473,608451) persulfide diox ( 243) 1154 276.7 2.6e-74
NP_001307798 (OMIM: 602473,608451) persulfide diox ( 156) 898 217.1 1.5e-56
NP_001307797 (OMIM: 602473,608451) persulfide diox ( 131) 896 216.6 1.7e-56
NP_072094 (OMIM: 118800,609023) probable hydrolase ( 361) 278 73.2 7.1e-13
NP_056303 (OMIM: 118800,609023) probable hydrolase ( 385) 278 73.2 7.5e-13
XP_016878684 (OMIM: 138760,614033) PREDICTED: hydr ( 258) 252 67.1 3.5e-11
NP_001035517 (OMIM: 138760,614033) hydroxyacylglut ( 260) 252 67.1 3.5e-11
XP_011520771 (OMIM: 138760,614033) PREDICTED: hydr ( 306) 252 67.1 4e-11
NP_005317 (OMIM: 138760,614033) hydroxyacylglutath ( 308) 252 67.2 4.1e-11
XP_016859261 (OMIM: 118800,609023) PREDICTED: prob ( 332) 232 62.5 1.1e-09
XP_016859260 (OMIM: 118800,609023) PREDICTED: prob ( 356) 232 62.5 1.2e-09
>>NP_055112 (OMIM: 602473,608451) persulfide dioxygenase (254 aa)
initn: 1713 init1: 1713 opt: 1713 Z-score: 2156.8 bits: 406.6 E(85289): 2.1e-113
Smith-Waterman score: 1713; 100.0% identity (100.0% similar) in 254 aa overlap (1-254:1-254)
10 20 30 40 50 60
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA
190 200 210 220 230 240
250
pF1KB8 VPANMRCGVQTPTA
::::::::::::::
NP_055 VPANMRCGVQTPTA
250
>>XP_005258744 (OMIM: 602473,608451) PREDICTED: persulfi (227 aa)
initn: 1545 init1: 1545 opt: 1545 Z-score: 1946.5 bits: 367.6 E(85289): 1.1e-101
Smith-Waterman score: 1545; 100.0% identity (100.0% similar) in 227 aa overlap (28-254:1-227)
10 20 30 40 50 60
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
:::::::::::::::::::::::::::::::::
XP_005 MFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
10 20 30
70 80 90 100 110 120
pF1KB8 DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA
160 170 180 190 200 210
250
pF1KB8 VPANMRCGVQTPTA
::::::::::::::
XP_005 VPANMRCGVQTPTA
220
>>NP_001307796 (OMIM: 602473,608451) persulfide dioxygen (243 aa)
initn: 1616 init1: 1154 opt: 1154 Z-score: 1455.0 bits: 276.7 E(85289): 2.6e-74
Smith-Waterman score: 1598; 95.7% identity (95.7% similar) in 254 aa overlap (1-254:1-243)
10 20 30 40 50 60
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI
::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_001 DAQLIKELGLRLLYA-----------GSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI
70 80 90 100
130 140 150 160 170 180
pF1KB8 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA
170 180 190 200 210 220
250
pF1KB8 VPANMRCGVQTPTA
::::::::::::::
NP_001 VPANMRCGVQTPTA
230 240
>>NP_001307798 (OMIM: 602473,608451) persulfide dioxygen (156 aa)
initn: 898 init1: 898 opt: 898 Z-score: 1136.4 bits: 217.1 E(85289): 1.5e-56
Smith-Waterman score: 898; 99.2% identity (99.2% similar) in 131 aa overlap (124-254:26-156)
100 110 120 130 140 150
pF1KB8 LLPGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLNDHSMAFTG
: ::::::::::::::::::::::::::::
NP_001 MAEAVLRVARRQLSQRGGSGAPILLRQALETRASPGHTPGCVTFVLNDHSMAFTG
10 20 30 40 50
160 170 180 190 200 210
pF1KB8 DALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNP
60 70 80 90 100 110
220 230 240 250
pF1KB8 RLTLSCEEFVKIMGNLNLPKPQQIDFAVPANMRCGVQTPTA
:::::::::::::::::::::::::::::::::::::::::
NP_001 RLTLSCEEFVKIMGNLNLPKPQQIDFAVPANMRCGVQTPTA
120 130 140 150
>>NP_001307797 (OMIM: 602473,608451) persulfide dioxygen (131 aa)
initn: 896 init1: 896 opt: 896 Z-score: 1135.1 bits: 216.6 E(85289): 1.7e-56
Smith-Waterman score: 896; 99.2% identity (100.0% similar) in 130 aa overlap (125-254:2-131)
100 110 120 130 140 150
pF1KB8 LPGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLNDHSMAFTGD
.:::::::::::::::::::::::::::::
NP_001 MLALETRASPGHTPGCVTFVLNDHSMAFTGD
10 20 30
160 170 180 190 200 210
pF1KB8 ALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPR
40 50 60 70 80 90
220 230 240 250
pF1KB8 LTLSCEEFVKIMGNLNLPKPQQIDFAVPANMRCGVQTPTA
::::::::::::::::::::::::::::::::::::::::
NP_001 LTLSCEEFVKIMGNLNLPKPQQIDFAVPANMRCGVQTPTA
100 110 120 130
>>NP_072094 (OMIM: 118800,609023) probable hydrolase PNK (361 aa)
initn: 297 init1: 73 opt: 278 Z-score: 352.2 bits: 73.2 E(85289): 7.1e-13
Smith-Waterman score: 278; 31.2% identity (55.8% similar) in 224 aa overlap (6-214:73-289)
10 20 30
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILL---RQMFEPV
:: :: . . .. : :. . . ::
NP_072 LMAHSQRLLFRIGYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB8 -SCTFTYLLGDRESREAVLIDPVLETAPRDAQL-IKELGLRLLYAVNTHCHADHITGSGL
: ...::. : ... :: .:: . :: .: :.. :. :. . :: : :: :.
NP_072 LSDNYSYLIIDTQAQLAVAVDP---SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRD
110 120 130 140 150
100 110 120 130 140
pF1KB8 LRSLLPGCQSVISRLSGAQADLH-IEDGDSIRFGRFALETRASPGHTPGCVTFVLNDH--
: :. : .: : . : . ::. ... :.:::: : ....:. .
NP_072 LSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPY
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB8 ---SMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYH----GF
: :.:: :.. ::::: :. : :.:. :. . .. : : :..:.:.: ::
NP_072 KGPSCLFSGDLLFLSGCGRT-FE-GNAETMLSSL-DTVLGLGDDTLLWPGHEYAEENLGF
220 230 240 250 260 270
210 220 230 240 250
pF1KB8 TVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFAVPANMRCGVQTPTA
. ..:: : :
NP_072 A-GVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPG
280 290 300 310 320 330
>>NP_056303 (OMIM: 118800,609023) probable hydrolase PNK (385 aa)
initn: 297 init1: 73 opt: 278 Z-score: 351.7 bits: 73.2 E(85289): 7.5e-13
Smith-Waterman score: 278; 31.2% identity (55.8% similar) in 224 aa overlap (6-214:97-313)
10 20 30
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILL---RQMFEPV
:: :: . . .. : :. . . ::
NP_056 RGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPV
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB8 -SCTFTYLLGDRESREAVLIDPVLETAPRDAQL-IKELGLRLLYAVNTHCHADHITGSGL
: ...::. : ... :: .:: . :: .: :.. :. :. . :: : :: :.
NP_056 LSDNYSYLIIDTQAQLAVAVDP---SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRD
130 140 150 160 170 180
100 110 120 130 140
pF1KB8 LRSLLPGCQSVISRLSGAQADLH-IEDGDSIRFGRFALETRASPGHTPGCVTFVLNDH--
: :. : .: : . : . ::. ... :.:::: : ....:. .
NP_056 LSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPY
190 200 210 220 230 240
150 160 170 180 190 200
pF1KB8 ---SMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYH----GF
: :.:: :.. ::::: :. : :.:. :. . .. : : :..:.:.: ::
NP_056 KGPSCLFSGDLLFLSGCGRT-FE-GNAETMLSSL-DTVLGLGDDTLLWPGHEYAEENLGF
250 260 270 280 290 300
210 220 230 240 250
pF1KB8 TVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFAVPANMRCGVQTPTA
. ..:: : :
NP_056 A-GVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPG
310 320 330 340 350
>>XP_016878684 (OMIM: 138760,614033) PREDICTED: hydroxya (258 aa)
initn: 217 init1: 73 opt: 252 Z-score: 321.7 bits: 67.1 E(85289): 3.5e-11
Smith-Waterman score: 252; 27.5% identity (58.0% similar) in 193 aa overlap (27-213:4-188)
10 20 30 40 50 60
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
... .. .. ::. : :..::...:::
XP_016 MKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVV
10 20 30
70 80 90 100 110
pF1KB8 DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLH-IEDGDS
:: .. :..: ...:: : :: :. : .: : . : . . : : : ..
XP_016 DAA--RKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLK-VYGGDDRIGALTHKITHLST
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB8 IRFGRFALETRASPGHTPGCVTFVLN-----DHSMAFTGDALLIRGCGRTDFQQGCAKTL
.. : . .. :.: :: : . . .. . .::::.:.. :::. : .: : .
XP_016 LQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGK--FYEGTADEM
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 YHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKP
... : . :: : .: .:.: :..... : ..:
XP_016 CKALLEVLGRLPPDTRVYCGHEY---TINNLKFARHVEPGNAAIREKLAWAKEKYSIGEP
160 170 180 190 200
240 250
pF1KB8 QQIDFAVPANMRCGVQTPTA
XP_016 TVPSTLAEEFTYNPFMRVSGPGSSGGRGSAQPAARCWPPQGEDGAAARR
210 220 230 240 250
>>NP_001035517 (OMIM: 138760,614033) hydroxyacylglutathi (260 aa)
initn: 212 init1: 73 opt: 252 Z-score: 321.7 bits: 67.1 E(85289): 3.5e-11
Smith-Waterman score: 252; 27.5% identity (58.0% similar) in 193 aa overlap (27-213:4-188)
10 20 30 40 50 60
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
... .. .. ::. : :..::...:::
NP_001 MKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVV
10 20 30
70 80 90 100 110
pF1KB8 DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLH-IEDGDS
:: .. :..: ...:: : :: :. : .: : . : . . : : : ..
NP_001 DAA--RKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLK-VYGGDDRIGALTHKITHLST
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB8 IRFGRFALETRASPGHTPGCVTFVLN-----DHSMAFTGDALLIRGCGRTDFQQGCAKTL
.. : . .. :.: :: : . . .. . .::::.:.. :::. : .: : .
NP_001 LQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGK--FYEGTADEM
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 YHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKP
... : . :: : .: .:.: :..... : ..:
NP_001 CKALLEVLGRLPPDTRVYCGHEY---TINNLKFARHVEPGNAAIREKLAWAKEKYSIGEP
160 170 180 190 200
240 250
pF1KB8 QQIDFAVPANMRCGVQTPTA
NP_001 TVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVTTMRAVRREKDQFKMPRD
210 220 230 240 250 260
>>XP_011520771 (OMIM: 138760,614033) PREDICTED: hydroxya (306 aa)
initn: 217 init1: 73 opt: 252 Z-score: 320.6 bits: 67.1 E(85289): 4e-11
Smith-Waterman score: 252; 27.5% identity (58.0% similar) in 193 aa overlap (27-213:52-236)
10 20 30 40 50
pF1KB8 MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLE
... .. .. ::. : :..::...:::
XP_011 RRGLGPALLGVFCHTDLRKNLTVDEGTMKVEVLPALTDNYMYLVIDDETKEAAIVDPVQP
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB8 TAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLH-IE
:: .. :..: ...:: : :: :. : .: : . : . . : : :
XP_011 QKVVDAA--RKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLK-VYGGDDRIGALTHKIT
90 100 110 120 130
120 130 140 150 160 170
pF1KB8 DGDSIRFGRFALETRASPGHTPGCVTFVLN-----DHSMAFTGDALLIRGCGRTDFQQGC
.... : . .. :.: :: : . . .. . .::::.:.. :::. : .:
XP_011 HLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGK--FYEGT
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB8 AKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLN
: . ... : . :: : .: .:.: :..... : ..:
XP_011 ADEMCKALLEVLGRLPPDTRVYCGHEY---TINNLKFARHVEPGNAAIREKLAWAKEKYS
200 210 220 230 240 250
240 250
pF1KB8 LPKPQQIDFAVPANMRCGVQTPTA
XP_011 IGEPTVPSTLAEEFTYNPFMRVSGPGSSGGRGSAQPAARCWPPQGEDGAAARR
260 270 280 290 300
254 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:46:57 2016 done: Fri Nov 4 11:46:58 2016
Total Scan time: 5.590 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]