Result of FASTA (ccds) for
pF1KB8285
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8285, 394 aa
1>>>pF1KB8285 394 - 394 aa - 394 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7676+/-0.00103; mu= 15.1272+/- 0.062
mean_var=73.9558+/-15.215, 0's: 0 Z-trim(104.0): 24 B-trim: 402 in 1/48
Lambda= 0.149138
statistics sampled from 7652 (7663) to 7652 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.596), E-opt: 0.2 (0.235), width: 16
Scan time: 2.390
The best scores are: opt bits E(32554)
CCDS8902.1 PA2G4 gene_id:5036|Hs108|chr12 ( 394) 2547 557.5 7.5e-159
CCDS81723.1 METAP2 gene_id:10988|Hs108|chr12 ( 455) 385 92.4 9.2e-19
CCDS81725.1 METAP2 gene_id:10988|Hs108|chr12 ( 455) 385 92.4 9.2e-19
CCDS81724.1 METAP2 gene_id:10988|Hs108|chr12 ( 477) 385 92.4 9.6e-19
CCDS9052.1 METAP2 gene_id:10988|Hs108|chr12 ( 478) 385 92.4 9.6e-19
>>CCDS8902.1 PA2G4 gene_id:5036|Hs108|chr12 (394 aa)
initn: 2547 init1: 2547 opt: 2547 Z-score: 2965.3 bits: 557.5 E(32554): 7.5e-159
Smith-Waterman score: 2547; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB8 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 GKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIAN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 VAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 PIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 GQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 GQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 LLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS
310 320 330 340 350 360
370 380 390
pF1KB8 SASRKTQKKKKKKASKTAENATSGETLEENEAGD
::::::::::::::::::::::::::::::::::
CCDS89 SASRKTQKKKKKKASKTAENATSGETLEENEAGD
370 380 390
>>CCDS81723.1 METAP2 gene_id:10988|Hs108|chr12 (455 aa)
initn: 108 init1: 108 opt: 385 Z-score: 450.3 bits: 92.4 E(32554): 9.2e-19
Smith-Waterman score: 385; 23.8% identity (59.8% similar) in 336 aa overlap (5-336:130-452)
10 20 30
pF1KB8 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRS
.:.. : . . . .. ... .: .
CCDS81 KKKKKKKRGRQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKY
100 110 120 130 140 150
40 50 60 70 80 90
pF1KB8 LVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKS
.. . :.... .::: .:. .. . ::. .. :.::::. :.:::. :..: .
CCDS81 VMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAG
160 170 180 190 200 210
100 110 120 130 140 150
pF1KB8 DQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAAL
: .:. :. :::.:.:..: : . : : . . : . . : :. ... :: .
CCDS81 DTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTGIKCAGIDV
220 230 240 250 260 270
160 170 180 190 200 210
pF1KB8 RLVKPGNQNTQVTEAWN-KV-AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKD
:: :. .: :... .. ..... ::... .:.. :. : . ::. : :
CCDS81 RLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV---PI---VKG
280 290 300 310 320
220 230 240 250 260 270
pF1KB8 HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERR
: ...: ::::.... :.:.: ..: . . .: . ... .. ... ...
CCDS81 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN
330 340 350 360 370 380
280 290 300 310 320 330
pF1KB8 FDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGP
: .. : : .. :.: :.. . ...:. : . .: ..:::. :.:: :.
CCDS81 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCK
390 400 410 420 430 440
340 350 360 370 380 390
pF1KB8 MRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEEN
.. :
CCDS81 EVVSRGDDY
450
>>CCDS81725.1 METAP2 gene_id:10988|Hs108|chr12 (455 aa)
initn: 166 init1: 108 opt: 385 Z-score: 450.3 bits: 92.4 E(32554): 9.2e-19
Smith-Waterman score: 385; 23.8% identity (59.8% similar) in 336 aa overlap (5-336:130-452)
10 20 30
pF1KB8 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRS
.:.. : . . . .. ... .: .
CCDS81 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKY
100 110 120 130 140 150
40 50 60 70 80 90
pF1KB8 LVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKS
.. . :.... .::: .:. .. . ::. .. :.::::. :.:::. :..: .
CCDS81 VMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAG
160 170 180 190 200 210
100 110 120 130 140 150
pF1KB8 DQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAAL
: .:. :. :::.:.:..: : . : : . . : . . : :. ... :: .
CCDS81 DTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTGIKCAGIDV
220 230 240 250 260 270
160 170 180 190 200 210
pF1KB8 RLVKPGNQNTQVTEAWN-KV-AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKD
:: :. .: :... .. ..... ::... .:.. :. : . ::. : :
CCDS81 RLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV---PI---VKG
280 290 300 310 320
220 230 240 250 260 270
pF1KB8 HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERR
: ...: ::::.... :.:.: ..: . . .: . ... .. ... ...
CCDS81 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN
330 340 350 360 370 380
280 290 300 310 320 330
pF1KB8 FDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGP
: .. : : .. :.: :.. . ...:. : . .: ..:::. :.:: :.
CCDS81 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCK
390 400 410 420 430 440
340 350 360 370 380 390
pF1KB8 MRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEEN
.. :
CCDS81 EVVSRGDDY
450
>>CCDS81724.1 METAP2 gene_id:10988|Hs108|chr12 (477 aa)
initn: 141 init1: 108 opt: 385 Z-score: 450.0 bits: 92.4 E(32554): 9.6e-19
Smith-Waterman score: 385; 23.8% identity (59.8% similar) in 336 aa overlap (5-336:152-474)
10 20 30
pF1KB8 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRS
.:.. : . . . .. ... .: .
CCDS81 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKY
130 140 150 160 170 180
40 50 60 70 80 90
pF1KB8 LVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKS
.. . :.... .::: .:. .. . ::. .. :.::::. :.:::. :..: .
CCDS81 VMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAG
190 200 210 220 230
100 110 120 130 140 150
pF1KB8 DQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAAL
: .:. :. :::.:.:..: : . : : . . : . . : :. ... :: .
CCDS81 DTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTGIKCAGIDV
240 250 260 270 280 290
160 170 180 190 200 210
pF1KB8 RLVKPGNQNTQVTEAWN-KV-AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKD
:: :. .: :... .. ..... ::... .:.. :. : . ::. : :
CCDS81 RLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV---PI---VKG
300 310 320 330 340
220 230 240 250 260 270
pF1KB8 HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERR
: ...: ::::.... :.:.: ..: . . .: . ... .. ... ...
CCDS81 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN
350 360 370 380 390 400
280 290 300 310 320 330
pF1KB8 FDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGP
: .. : : .. :.: :.. . ...:. : . .: ..:::. :.:: :.
CCDS81 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCK
410 420 430 440 450 460
340 350 360 370 380 390
pF1KB8 MRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEEN
.. :
CCDS81 EVVSRGDDY
470
>>CCDS9052.1 METAP2 gene_id:10988|Hs108|chr12 (478 aa)
initn: 141 init1: 108 opt: 385 Z-score: 450.0 bits: 92.4 E(32554): 9.6e-19
Smith-Waterman score: 385; 23.8% identity (59.8% similar) in 336 aa overlap (5-336:153-475)
10 20 30
pF1KB8 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRS
.:.. : . . . .. ... .: .
CCDS90 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKY
130 140 150 160 170 180
40 50 60 70 80 90
pF1KB8 LVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKS
.. . :.... .::: .:. .. . ::. .. :.::::. :.:::. :..: .
CCDS90 VMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAG
190 200 210 220 230
100 110 120 130 140 150
pF1KB8 DQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAAL
: .:. :. :::.:.:..: : . : : . . : . . : :. ... :: .
CCDS90 DTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTGIKCAGIDV
240 250 260 270 280 290
160 170 180 190 200 210
pF1KB8 RLVKPGNQNTQVTEAWN-KV-AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKD
:: :. .: :... .. ..... ::... .:.. :. : . ::. : :
CCDS90 RLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV---PI---VKG
300 310 320 330 340
220 230 240 250 260 270
pF1KB8 HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERR
: ...: ::::.... :.:.: ..: . . .: . ... .. ... ...
CCDS90 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN
350 360 370 380 390 400
280 290 300 310 320 330
pF1KB8 FDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGP
: .. : : .. :.: :.. . ...:. : . .: ..:::. :.:: :.
CCDS90 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCK
410 420 430 440 450 460
340 350 360 370 380 390
pF1KB8 MRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEEN
.. :
CCDS90 EVVSRGDDY
470
394 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:24:05 2016 done: Fri Nov 4 11:24:06 2016
Total Scan time: 2.390 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]