Result of FASTA (omim) for
pF1KB8256
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8256, 355 aa
1>>>pF1KB8256 355 - 355 aa - 355 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6004+/-0.000336; mu= 7.5234+/- 0.021
mean_var=133.4330+/-26.930, 0's: 0 Z-trim(119.4): 61 B-trim: 438 in 1/52
Lambda= 0.111031
statistics sampled from 33238 (33301) to 33238 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.39), width: 16
Scan time: 7.840
The best scores are: opt bits E(85289)
NP_003155 (OMIM: 603189) syntaxin-5 isoform 1 [Hom ( 355) 2239 369.4 6.6e-102
NP_001231595 (OMIM: 603189) syntaxin-5 isoform 2 [ ( 321) 1913 317.2 3.2e-86
NP_001317223 (OMIM: 603189) syntaxin-5 isoform 3 [ ( 301) 1877 311.4 1.6e-84
XP_011543526 (OMIM: 603189) PREDICTED: syntaxin-5 ( 259) 1602 267.3 2.6e-71
NP_003560 (OMIM: 603217) syntaxin-7 isoform a [Hom ( 261) 184 40.2 0.0063
NP_001313507 (OMIM: 603217) syntaxin-7 isoform a [ ( 261) 184 40.2 0.0063
NP_001313508 (OMIM: 603217) syntaxin-7 isoform a [ ( 261) 184 40.2 0.0063
XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 ( 260) 181 39.7 0.0088
NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Hom ( 288) 181 39.7 0.0096
>>NP_003155 (OMIM: 603189) syntaxin-5 isoform 1 [Homo sa (355 aa)
initn: 2239 init1: 2239 opt: 2239 Z-score: 1950.5 bits: 369.4 E(85289): 6.6e-102
Smith-Waterman score: 2239; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KB8 MIPRKRYGSKNTDQGVYLGLSKTQVLSPATAGSSSSDIAPLPPPVTLVPPPPDTMSCRDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MIPRKRYGSKNTDQGVYLGLSKTQVLSPATAGSSSSDIAPLPPPVTLVPPPPDTMSCRDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TQEFLSACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TQEFLSACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEET
250 260 270 280 290 300
310 320 330 340 350
pF1KB8 IQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
310 320 330 340 350
>>NP_001231595 (OMIM: 603189) syntaxin-5 isoform 2 [Homo (321 aa)
initn: 1969 init1: 1913 opt: 1913 Z-score: 1668.9 bits: 317.2 E(85289): 3.2e-86
Smith-Waterman score: 1913; 99.3% identity (99.7% similar) in 304 aa overlap (1-304:1-304)
10 20 30 40 50 60
pF1KB8 MIPRKRYGSKNTDQGVYLGLSKTQVLSPATAGSSSSDIAPLPPPVTLVPPPPDTMSCRDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPRKRYGSKNTDQGVYLGLSKTQVLSPATAGSSSSDIAPLPPPVTLVPPPPDTMSCRDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TQEFLSACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQEFLSACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEET
250 260 270 280 290 300
310 320 330 340 350
pF1KB8 IQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
:: .
NP_001 IQSVLLFPLLPALSPGSTRTC
310 320
>>NP_001317223 (OMIM: 603189) syntaxin-5 isoform 3 [Homo (301 aa)
initn: 1877 init1: 1877 opt: 1877 Z-score: 1638.2 bits: 311.4 E(85289): 1.6e-84
Smith-Waterman score: 1877; 100.0% identity (100.0% similar) in 301 aa overlap (55-355:1-301)
30 40 50 60 70 80
pF1KB8 VLSPATAGSSSSDIAPLPPPVTLVPPPPDTMSCRDRTQEFLSACKSLQTRQNGIQTNKPA
::::::::::::::::::::::::::::::
NP_001 MSCRDRTQEFLSACKSLQTRQNGIQTNKPA
10 20 30
90 100 110 120 130 140
pF1KB8 LRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDIN
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB8 SLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQ
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB8 RSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB8 YIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILK
220 230 240 250 260 270
330 340 350
pF1KB8 YFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
:::::::::::::::::::::::::::::::
NP_001 YFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
280 290 300
>>XP_011543526 (OMIM: 603189) PREDICTED: syntaxin-5 isof (259 aa)
initn: 1602 init1: 1602 opt: 1602 Z-score: 1401.1 bits: 267.3 E(85289): 2.6e-71
Smith-Waterman score: 1602; 100.0% identity (100.0% similar) in 259 aa overlap (97-355:1-259)
70 80 90 100 110 120
pF1KB8 ACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAKRKSLFD
::::::::::::::::::::::::::::::
XP_011 MAKRIGKDLSNTFAKLEKLTILAKRKSLFD
10 20 30
130 140 150 160 170 180
pF1KB8 DKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASM
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB8 SNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAID
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB8 MMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDE
160 170 180 190 200 210
310 320 330 340 350
pF1KB8 NVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
220 230 240 250
>>NP_003560 (OMIM: 603217) syntaxin-7 isoform a [Homo sa (261 aa)
initn: 132 init1: 104 opt: 184 Z-score: 173.5 bits: 40.2 E(85289): 0.0063
Smith-Waterman score: 184; 21.8% identity (60.2% similar) in 211 aa overlap (141-345:43-247)
120 130 140 150 160 170
pF1KB8 KLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQT
:: : .:. : :... .... ....
NP_003 QLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKE
20 30 40 50 60 70
180 190 200 210 220
pF1KB8 HSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAP-VSALPLAPNHLGGG
.. .. ... ....: . : : : . :. .:. : : : ....:.
NP_003 FGSLPTTPSEQRQRKIQKD-RLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGS
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB8 AVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDS-----YIQSRADTMQNIESTIVELG
.::. . .:.:. :.:. ::. . :. : ......:. :....
NP_003 F-----PEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDIN
140 150 160 170 180
290 300 310 320 330 340
pF1KB8 SIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILI
::..:. :..:: ..:. :. :: .:.. :. :.... . . ..: . :.:::.
NP_003 EIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILV
190 200 210 220 230 240
350
pF1KB8 VFFIIFVVFLA
.
NP_003 IGVAIISLIIWGLNH
250 260
>>NP_001313507 (OMIM: 603217) syntaxin-7 isoform a [Homo (261 aa)
initn: 132 init1: 104 opt: 184 Z-score: 173.5 bits: 40.2 E(85289): 0.0063
Smith-Waterman score: 184; 21.8% identity (60.2% similar) in 211 aa overlap (141-345:43-247)
120 130 140 150 160 170
pF1KB8 KLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQT
:: : .:. : :... .... ....
NP_001 QLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKE
20 30 40 50 60 70
180 190 200 210 220
pF1KB8 HSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAP-VSALPLAPNHLGGG
.. .. ... ....: . : : : . :. .:. : : : ....:.
NP_001 FGSLPTTPSEQRQRKIQKD-RLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGS
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB8 AVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDS-----YIQSRADTMQNIESTIVELG
.::. . .:.:. :.:. ::. . :. : ......:. :....
NP_001 F-----PEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDIN
140 150 160 170 180
290 300 310 320 330 340
pF1KB8 SIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILI
::..:. :..:: ..:. :. :: .:.. :. :.... . . ..: . :.:::.
NP_001 EIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILV
190 200 210 220 230 240
350
pF1KB8 VFFIIFVVFLA
.
NP_001 IGVAIISLIIWGLNH
250 260
>>NP_001313508 (OMIM: 603217) syntaxin-7 isoform a [Homo (261 aa)
initn: 132 init1: 104 opt: 184 Z-score: 173.5 bits: 40.2 E(85289): 0.0063
Smith-Waterman score: 184; 21.8% identity (60.2% similar) in 211 aa overlap (141-345:43-247)
120 130 140 150 160 170
pF1KB8 KLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQT
:: : .:. : :... .... ....
NP_001 QLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKE
20 30 40 50 60 70
180 190 200 210 220
pF1KB8 HSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAP-VSALPLAPNHLGGG
.. .. ... ....: . : : : . :. .:. : : : ....:.
NP_001 FGSLPTTPSEQRQRKIQKD-RLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGS
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB8 AVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDS-----YIQSRADTMQNIESTIVELG
.::. . .:.:. :.:. ::. . :. : ......:. :....
NP_001 F-----PEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDIN
140 150 160 170 180
290 300 310 320 330 340
pF1KB8 SIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILI
::..:. :..:: ..:. :. :: .:.. :. :.... . . ..: . :.:::.
NP_001 EIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILV
190 200 210 220 230 240
350
pF1KB8 VFFIIFVVFLA
.
NP_001 IGVAIISLIIWGLNH
250 260
>>XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 isof (260 aa)
initn: 154 init1: 107 opt: 181 Z-score: 170.9 bits: 39.7 E(85289): 0.0088
Smith-Waterman score: 181; 24.5% identity (60.5% similar) in 220 aa overlap (139-351:42-254)
110 120 130 140 150 160
pF1KB8 FAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHL
::.....:::.: . . .::: . . .
XP_016 RNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSF
20 30 40 50 60 70
170 180 190 200 210 220
pF1KB8 -QTHS-NTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVS-ALPLAPNH
: .: : :.:. . .. : .. .:. .: . : ::. :.. .. : ..
XP_016 DQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRER-SKGRIQRQLEITGRT
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB8 LGGGAVVLGAESHASKDVAIDMM-DSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELG
. :: . . :.. ::. ..: ..: :.:: ....:..: ::
XP_016 TTDDELEEMLESGKPSIFTSDIISDSQITRQ--ALNE----IESRHKDIMKLETSIRELH
140 150 160 170 180
290 300 310 320 330 340
pF1KB8 SIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEI---LKYFQSVTSNRWLMVKIFL
.:...: .:. : : :. :..::..: :: :. : .:: ... ..:... . .
XP_016 EMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSV
190 200 210 220 230 240
350
pF1KB8 ILIVFFIIFVVFLA
.:.... ...
XP_016 VLVAIIALIIGLSVGK
250 260
>>NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Homo sa (288 aa)
initn: 177 init1: 107 opt: 181 Z-score: 170.3 bits: 39.7 E(85289): 0.0096
Smith-Waterman score: 181; 24.5% identity (60.5% similar) in 220 aa overlap (139-351:70-282)
110 120 130 140 150 160
pF1KB8 FAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHL
::.....:::.: . . .::: . . .
NP_919 RNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSF
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 -QTHS-NTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVS-ALPLAPNH
: .: : :.:. . .. : .. .:. .: . : ::. :.. .. : ..
NP_919 DQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRER-SKGRIQRQLEITGRT
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 LGGGAVVLGAESHASKDVAIDMM-DSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELG
. :: . . :.. ::. ..: ..: :.:: ....:..: ::
NP_919 TTDDELEEMLESGKPSIFTSDIISDSQITRQ--ALNE----IESRHKDIMKLETSIRELH
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 SIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEI---LKYFQSVTSNRWLMVKIFL
.:...: .:. : : :. :..::..: :: :. : .:: ... ..:... . .
NP_919 EMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSV
220 230 240 250 260 270
350
pF1KB8 ILIVFFIIFVVFLA
.:.... ...
NP_919 VLVAIIALIIGLSVGK
280
355 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:05:28 2016 done: Fri Nov 4 11:05:29 2016
Total Scan time: 7.840 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]