FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8248, 235 aa
  1>>>pF1KB8248 235 - 235 aa - 235 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9311+/-0.000721; mu= 16.0160+/- 0.043
 mean_var=57.5616+/-11.235, 0's: 0 Z-trim(108.4): 9  B-trim: 0 in 0/49
 Lambda= 0.169047
 statistics sampled from 10183 (10187) to 10183 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.313), width:  16
 Scan time:  2.110

The best scores are:                                      opt bits E(32554)
CCDS12580.1 EXOSC5 gene_id:56915|Hs108|chr19       ( 235) 1518 378.0 2.9e-105
CCDS6414.1 EXOSC4 gene_id:54512|Hs108|chr8         ( 245)  231 64.1 9.2e-11


>>CCDS12580.1 EXOSC5 gene_id:56915|Hs108|chr19            (235 aa)
 initn: 1518 init1: 1518 opt: 1518  Z-score: 2003.3  bits: 378.0 E(32554): 2.9e-105
Smith-Waterman score: 1518; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)

               10        20        30        40        50        60
pF1KB8 MEEETHTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MEEETHTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PAEVKVSKEIFNKATLEVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTLHPRTSITVVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PAEVKVSKEIFNKATLEVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTLHPRTSITVVL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 QVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALDSDGTLVLDPTSKQEKEARAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 QVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALDSDGTLVLDPTSKQEKEARAV
              130       140       150       160       170       180

              190       200       210       220       230     
pF1KB8 LTFALDSVERKLLMSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSKS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LTFALDSVERKLLMSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSKS
              190       200       210       220       230     

>>CCDS6414.1 EXOSC4 gene_id:54512|Hs108|chr8              (245 aa)
 initn: 284 init1: 190 opt: 231  Z-score: 306.7  bits: 64.1 E(32554): 9.2e-11
Smith-Waterman score: 300; 33.3% identity (60.8% similar) in 204 aa overlap (28-216:22-221)

               10        20        30        40        50        60
pF1KB8 MEEETHTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYG
                                  ::..  ....... :::: . ::.:..:: :::
CCDS64       MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYG
                     10        20        30        40        50    

                          70        80        90         100       
pF1KB8 PAEVKVSKE-----------IFNKATLEVILRPKIGLPGVAEKSRER--LIRNTCEAVVL
       : :.. :.             ...::. .  : .   :   .:: :    .:.: ::..:
CCDS64 PHEIRGSRARALPDRALVNCQYSSATFSTGERKR--RPHGDRKSCEMGLQLRQTFEAAIL
           60        70        80          90       100       110  

       110       120       130       140       150       160       
pF1KB8 GTLHPRTSITVVLQVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALD-SDGTLV
         ::::..: . .::..  :.  : :.::: .:..:::.::: . :  ::.    ::: .
CCDS64 TQLHPRSQIDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVC--ACSAGFVDGTAL
            120       130       140       150         160       170

        170       180       190       200       210        220     
pF1KB8 LDPTSKQEKEARAVLTFALDSVERKLLMSSTKGLYSDTELQQCL-AAAQAASQHVFRFYR
        : .  .:  .   :..::  .  .. .    .   . .:.. : ::::::         
CCDS64 ADLSHVEEAAGGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDR
              180       190       200       210       220       230

         230          
pF1KB8 ESLQRRYSKS     
                      
CCDS64 VVRQHVREASILLGD
              240     




235 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:58:47 2016 done: Fri Nov  4 10:58:48 2016
 Total Scan time:  2.110 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]