Result of FASTA (omim) for
pF1KB8218
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8218, 185 aa
1>>>pF1KB8218 185 - 185 aa - 185 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5951+/-0.0003; mu= 11.0589+/- 0.019
mean_var=59.4384+/-11.686, 0's: 0 Z-trim(117.4): 40 B-trim: 344 in 2/50
Lambda= 0.166357
statistics sampled from 29262 (29302) to 29262 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.344), width: 16
Scan time: 4.110
The best scores are: opt bits E(85289)
NP_001274692 (OMIM: 607645) neuron-specific protei ( 185) 1203 296.5 1.6e-80
NP_055207 (OMIM: 607645) neuron-specific protein f ( 185) 1203 296.5 1.6e-80
NP_001035190 (OMIM: 607645) neuron-specific protei ( 185) 1203 296.5 1.6e-80
XP_016863511 (OMIM: 607645) PREDICTED: neuron-spec ( 185) 1203 296.5 1.6e-80
NP_001274693 (OMIM: 607645) neuron-specific protei ( 158) 1024 253.5 1.2e-67
NP_057064 (OMIM: 616752) neuron-specific protein f ( 171) 381 99.2 3.7e-21
NP_056537 (OMIM: 604647) neuron-specific vesicular ( 217) 378 98.5 7.6e-21
XP_011538138 (OMIM: 604647) PREDICTED: neuron-spec ( 250) 205 57.0 2.7e-08
XP_005252742 (OMIM: 604647) PREDICTED: neuron-spec ( 250) 205 57.0 2.7e-08
XP_011538140 (OMIM: 604647) PREDICTED: neuron-spec ( 130) 197 55.0 5.6e-08
>>NP_001274692 (OMIM: 607645) neuron-specific protein fa (185 aa)
initn: 1203 init1: 1203 opt: 1203 Z-score: 1566.5 bits: 296.5 E(85289): 1.6e-80
Smith-Waterman score: 1203; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB8 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
130 140 150 160 170 180
pF1KB8 AEKSA
:::::
NP_001 AEKSA
>>NP_055207 (OMIM: 607645) neuron-specific protein famil (185 aa)
initn: 1203 init1: 1203 opt: 1203 Z-score: 1566.5 bits: 296.5 E(85289): 1.6e-80
Smith-Waterman score: 1203; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB8 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
130 140 150 160 170 180
pF1KB8 AEKSA
:::::
NP_055 AEKSA
>>NP_001035190 (OMIM: 607645) neuron-specific protein fa (185 aa)
initn: 1203 init1: 1203 opt: 1203 Z-score: 1566.5 bits: 296.5 E(85289): 1.6e-80
Smith-Waterman score: 1203; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB8 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
130 140 150 160 170 180
pF1KB8 AEKSA
:::::
NP_001 AEKSA
>>XP_016863511 (OMIM: 607645) PREDICTED: neuron-specific (185 aa)
initn: 1203 init1: 1203 opt: 1203 Z-score: 1566.5 bits: 296.5 E(85289): 1.6e-80
Smith-Waterman score: 1203; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB8 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
130 140 150 160 170 180
pF1KB8 AEKSA
:::::
XP_016 AEKSA
>>NP_001274693 (OMIM: 607645) neuron-specific protein fa (158 aa)
initn: 1024 init1: 1024 opt: 1024 Z-score: 1335.5 bits: 253.5 E(85289): 1.2e-67
Smith-Waterman score: 1024; 100.0% identity (100.0% similar) in 158 aa overlap (28-185:1-158)
10 20 30 40 50 60
pF1KB8 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
:::::::::::::::::::::::::::::::::
NP_001 MTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGK
10 20 30
70 80 90 100 110 120
pF1KB8 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEA
100 110 120 130 140 150
pF1KB8 AEKSA
:::::
NP_001 AEKSA
>>NP_057064 (OMIM: 616752) neuron-specific protein famil (171 aa)
initn: 613 init1: 362 opt: 381 Z-score: 500.9 bits: 99.2 E(85289): 3.7e-21
Smith-Waterman score: 656; 56.2% identity (81.2% similar) in 176 aa overlap (1-172:1-164)
10 20 30 40 50
pF1KB8 MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRK-KG
::::..: .::::: : .::::.:.::.:::.::.::.: :.::.:::.:::.:..: ::
NP_057 MVKLNSNPSEKGTKPPSVEDGFQTVPLITPLEVNHLQLPAPEKVIVKTRTEYQPEQKNKG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 KARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLK
: : :.::::::.: :: .:::::.:.:::::::.. ::..::.::: :
NP_057 KFRVPKIAEFTVTI------------LVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYK
70 80 90 100
120 130 140 150 160 170
pF1KB8 NTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMS---VLSEEKLSEQ
. .::: .:..::. :: ..: .:::::.::..:::: .:...::.: :. : :
NP_057 HKRCIPASLDAYYSSQDPNSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKT
110 120 130 140 150 160
180
pF1KB8 ETEAAEKSA
NP_057 QGH
170
>>NP_056537 (OMIM: 604647) neuron-specific vesicular pro (217 aa)
initn: 319 init1: 165 opt: 378 Z-score: 495.2 bits: 98.5 E(85289): 7.6e-21
Smith-Waterman score: 378; 38.8% identity (68.8% similar) in 170 aa overlap (1-164:1-165)
10 20 30 40 50
pF1KB8 MVKLGNNFAEKGTKQPLLEDG--FDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYE---PD
::::: .:. : :.: .:: .:..::..:::..::: : ::.::.::.:::. ::
NP_056 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 RKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDR-ACPD
... : . . :: .:. .. .. ::.:.: :: :..::. ::. .:::
NP_056 QQNFPDLEGQRLNCS-HPEEG--RRLPTARMIAFAMALLGCV--LIMYKAIWYDQFTCPD
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 GFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLS
::.:.. : : :: ::.:.: .... ..:. : :... :.. . :
NP_056 GFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEE
120 130 140 150 160 170
180
pF1KB8 EQETEAAEKSA
NP_056 RKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
180 190 200 210
>>XP_011538138 (OMIM: 604647) PREDICTED: neuron-specific (250 aa)
initn: 317 init1: 136 opt: 205 Z-score: 269.8 bits: 57.0 E(85289): 2.7e-08
Smith-Waterman score: 326; 33.5% identity (61.5% similar) in 200 aa overlap (1-164:1-198)
10 20 30 40 50
pF1KB8 MVKLGNNFAEKGTKQPLLEDG--FDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYE---PD
::::: .:. : :.: .:: .:..::..:::..::: : ::.::.::.:::. ::
XP_011 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
10 20 30 40 50 60
60 70 80
pF1KB8 RK-----KGK----ARPPQ----------IAEFTVSITEGVTER-----------FKVSV
.. .:. ..: . .: . . :: . . ..
XP_011 QQNFPDLEGQRLNCSHPEEGRRTDLLGLPAPGLTFQSAAHVTTHAPTVGSHLGGLLPTAR
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB8 LVLFALAFLTCVVFLVVYKVYKYDR-ACPDGFVLKNTQCIPEGLESYYAEQDSSAREKFY
.. ::.:.: :: :..::. ::. .:::::.:.. : : :: ::.:.: ....
XP_011 MIAFAMALLGCV--LIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSIL
130 140 150 160 170
150 160 170 180
pF1KB8 TVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEAAEKSA
..:. : :... :.. . :
XP_011 AAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAAR
180 190 200 210 220 230
>>XP_005252742 (OMIM: 604647) PREDICTED: neuron-specific (250 aa)
initn: 317 init1: 136 opt: 205 Z-score: 269.8 bits: 57.0 E(85289): 2.7e-08
Smith-Waterman score: 326; 33.5% identity (61.5% similar) in 200 aa overlap (1-164:1-198)
10 20 30 40 50
pF1KB8 MVKLGNNFAEKGTKQPLLEDG--FDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYE---PD
::::: .:. : :.: .:: .:..::..:::..::: : ::.::.::.:::. ::
XP_005 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
10 20 30 40 50 60
60 70 80
pF1KB8 RK-----KGK----ARPPQ----------IAEFTVSITEGVTER-----------FKVSV
.. .:. ..: . .: . . :: . . ..
XP_005 QQNFPDLEGQRLNCSHPEEGRRTDLLGLPAPGLTFQSAAHVTTHAPTVGSHLGGLLPTAR
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB8 LVLFALAFLTCVVFLVVYKVYKYDR-ACPDGFVLKNTQCIPEGLESYYAEQDSSAREKFY
.. ::.:.: :: :..::. ::. .:::::.:.. : : :: ::.:.: ....
XP_005 MIAFAMALLGCV--LIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSIL
130 140 150 160 170
150 160 170 180
pF1KB8 TVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEAAEKSA
..:. : :... :.. . :
XP_005 AAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAAR
180 190 200 210 220 230
>>XP_011538140 (OMIM: 604647) PREDICTED: neuron-specific (130 aa)
initn: 155 init1: 109 opt: 197 Z-score: 264.2 bits: 55.0 E(85289): 5.6e-08
Smith-Waterman score: 197; 37.5% identity (71.2% similar) in 80 aa overlap (86-164:1-78)
60 70 80 90 100 110
pF1KB8 RKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDR-ACPD
.. ::.:.: :: :..::. ::. .:::
XP_011 MIAFAMALLGCV--LIMYKAIWYDQFTCPD
10 20
120 130 140 150 160 170
pF1KB8 GFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLS
::.:.. : : :: ::.:.: .... ..:. : :... :.. . :
XP_011 GFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEE
30 40 50 60 70 80
180
pF1KB8 EQETEAAEKSA
XP_011 RKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
90 100 110 120 130
185 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:39:36 2016 done: Fri Nov 4 10:39:37 2016
Total Scan time: 4.110 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]