Result of FASTA (omim) for
pF1KB8193
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8193, 119 aa
1>>>pF1KB8193 119 - 119 aa - 119 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6767+/-0.000219; mu= 10.2104+/- 0.014
mean_var=75.9520+/-14.981, 0's: 0 Z-trim(124.1): 12 B-trim: 0 in 0/59
Lambda= 0.147165
statistics sampled from 45168 (45181) to 45168 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.853), E-opt: 0.2 (0.53), width: 16
Scan time: 4.730
The best scores are: opt bits E(85289)
NP_002158 (OMIM: 600277) DNA-binding protein inhib ( 119) 807 178.9 1.6e-45
NP_851998 (OMIM: 600349) DNA-binding protein inhib ( 149) 275 66.1 2e-11
NP_002156 (OMIM: 600349) DNA-binding protein inhib ( 155) 275 66.1 2e-11
NP_002157 (OMIM: 600386) DNA-binding protein inhib ( 134) 272 65.4 2.8e-11
NP_001537 (OMIM: 600581) DNA-binding protein inhib ( 161) 273 65.6 2.8e-11
XP_005268588 (OMIM: 602406) PREDICTED: heart- and ( 214) 146 38.7 0.0047
>>NP_002158 (OMIM: 600277) DNA-binding protein inhibitor (119 aa)
initn: 807 init1: 807 opt: 807 Z-score: 938.1 bits: 178.9 E(85289): 1.6e-45
Smith-Waterman score: 807; 99.2% identity (100.0% similar) in 119 aa overlap (1-119:1-119)
10 20 30 40 50 60
pF1KB8 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELAPELVISNDKRSFCH
::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
NP_002 GTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELTPELVISNDKRSFCH
70 80 90 100 110
>>NP_851998 (OMIM: 600349) DNA-binding protein inhibitor (149 aa)
initn: 248 init1: 192 opt: 275 Z-score: 326.2 bits: 66.1 E(85289): 2e-11
Smith-Waterman score: 276; 49.1% identity (69.1% similar) in 110 aa overlap (1-100:19-126)
10 20 30 40
pF1KB8 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLD
.:: . . : :.: ::::.:.::.: : : .:. : .:::
NP_851 MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAG-GAGARLP-ALLD
10 20 30 40 50
50 60 70 80 90
pF1KB8 ---------DMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVL-AEPAPGPP
::: :::::.:::: .:.. ..:.:::::.::::: :::. : .: : :
NP_851 EQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTP
60 70 80 90 100 110
100 110
pF1KB8 DGPHLPIQTAELAPELVISNDKRSFCH
: ::..
NP_851 GGRGLPVRAPLSTLNGEISALTAEVRSRSDH
120 130 140
>>NP_002156 (OMIM: 600349) DNA-binding protein inhibitor (155 aa)
initn: 248 init1: 192 opt: 275 Z-score: 325.9 bits: 66.1 E(85289): 2e-11
Smith-Waterman score: 276; 49.1% identity (69.1% similar) in 110 aa overlap (1-100:19-126)
10 20 30 40
pF1KB8 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLD
.:: . . : :.: ::::.:.::.: : : .:. : .:::
NP_002 MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAG-GAGARLP-ALLD
10 20 30 40 50
50 60 70 80 90
pF1KB8 ---------DMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVL-AEPAPGPP
::: :::::.:::: .:.. ..:.:::::.::::: :::. : .: : :
NP_002 EQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTP
60 70 80 90 100 110
100 110
pF1KB8 DGPHLPIQTAELAPELVISNDKRSFCH
: ::..
NP_002 GGRGLPVRAPLSTLNGEISALTAEAACVPADDRILCR
120 130 140 150
>>NP_002157 (OMIM: 600386) DNA-binding protein inhibitor (134 aa)
initn: 283 init1: 203 opt: 272 Z-score: 323.4 bits: 65.4 E(85289): 2.8e-11
Smith-Waterman score: 288; 41.0% identity (70.5% similar) in 139 aa overlap (1-118:1-133)
10 20 30 40 50 60
pF1KB8 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR
:::.::::. . ::..::.:.:. : :. ..:.::: .:: :::.:.::::..:.
NP_002 MKAFSPVRSVRKN--SLSDHSLGISRS--KTPV-DDPMSLLYNMNDCYSKLKELVPSIPQ
10 20 30 40 50
70 80 90
pF1KB8 GTQLSQVEILQRVIDYILDLQVVL-AEPA--------PGPPDGPHLPI------------
. ..:..::::.:::::::::..: ..:. :: .. . :.
NP_002 NKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSL
60 70 80 90 100 110
100 110
pF1KB8 QTAELAPELVISNDKRSFCH
:..:. :: .:::....:
NP_002 QASEFPSEL-MSNDSKALCG
120 130
>>NP_001537 (OMIM: 600581) DNA-binding protein inhibitor (161 aa)
initn: 301 init1: 194 opt: 273 Z-score: 323.4 bits: 65.6 E(85289): 2.8e-11
Smith-Waterman score: 286; 47.4% identity (60.7% similar) in 135 aa overlap (1-106:1-135)
10 20 30
pF1KB8 MKALSPVR--------GC---YEAVCCLSER--SL----------AIARGRGKGPAAEEP
:::.:::: :: :. ::.:. :: : :: .. ::.::
NP_001 MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAARCKAAEAAADEP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 -LSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVL-AEPA----PGP
: : ::: ::::::.::: .: . ..:.:::::.:::::::::..: ..:: : :
NP_001 ALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPP
70 80 90 100 110 120
100 110
pF1KB8 PDGPHLPIQTAELAPELVISNDKRSFCH
: :: : : ::
NP_001 PAPPHHPAGTCPAAPPRTPLTALNTDPAGAVNKQGDSILCR
130 140 150 160
>>XP_005268588 (OMIM: 602406) PREDICTED: heart- and neur (214 aa)
initn: 142 init1: 127 opt: 146 Z-score: 175.8 bits: 38.7 E(85289): 0.0047
Smith-Waterman score: 146; 32.0% identity (64.9% similar) in 97 aa overlap (24-119:92-183)
10 20 30 40 50
pF1KB8 MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRE
..: .:.:: :. . ...: ...:::
XP_005 PPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRT--ESINSAFAELRE
70 80 90 100 110
60 70 80 90 100 110
pF1KB8 LVPGVPRGTQLSQVEILQRVIDYILDLQVVLAEPAP-GPPDGPHLPIQTAELAPELVISN
.:.:: :.::... :. . .:: :. :::. : : :.. . .. :. . : :.
XP_005 CIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRE---SK
120 130 140 150 160 170
pF1KB8 DKRSFCH
:: . :
XP_005 RKRELQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ
180 190 200 210
119 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:50:36 2016 done: Fri Nov 4 19:50:37 2016
Total Scan time: 4.730 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]