Result of FASTA (ccds) for
pF1KB8186
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8186, 303 aa
1>>>pF1KB8186 303 - 303 aa - 303 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4880+/-0.00076; mu= 14.5659+/- 0.046
mean_var=67.6101+/-13.261, 0's: 0 Z-trim(108.0): 11 B-trim: 0 in 0/52
Lambda= 0.155980
statistics sampled from 9935 (9942) to 9935 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.305), width: 16
Scan time: 2.360
The best scores are: opt bits E(32554)
CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 ( 303) 2095 480.1 8.7e-136
CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 ( 290) 512 123.9 1.4e-28
CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX ( 357) 476 115.8 4.7e-26
CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX ( 353) 393 97.2 2e-20
CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 ( 291) 389 96.2 3.1e-20
CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 ( 279) 317 80.0 2.3e-15
>>CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 (303 aa)
initn: 2095 init1: 2095 opt: 2095 Z-score: 2551.3 bits: 480.1 E(32554): 8.7e-136
Smith-Waterman score: 2095; 100.0% identity (100.0% similar) in 303 aa overlap (1-303:1-303)
10 20 30 40 50 60
pF1KB8 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 MIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 NRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 QYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIE
250 260 270 280 290 300
pF1KB8 VKS
:::
CCDS12 VKS
>>CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 (290 aa)
initn: 661 init1: 347 opt: 512 Z-score: 626.4 bits: 123.9 E(32554): 1.4e-28
Smith-Waterman score: 729; 39.5% identity (67.4% similar) in 304 aa overlap (4-301:11-287)
10 20 30 40 50
pF1KB8 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGT
:.. :: ::.:.:: . ..:.:::: :: :::::..::: :...: :
CCDS32 MVIQKEKKSCGQVVEE--WKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLT
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 IQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYK
. ::: :.:. : ::::.: ::: :. .. .. .: .:.. .: .. .::: :.
CCDS32 MWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYN
60 70 80 90 100 110
120 130 140 150 160
pF1KB8 DS--AQRDDMIFEDC--GDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDET-YG
:: ::..:. : : .: . : .:. . ..:.:. ::::::..: : ::
CCDS32 DSIQAQKNDV----CRPGRYYEQP-DNGVLNYPK---RACQFNRTQLGNCSGIGDSTHYG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 YKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVE
:. :.::..::.:::..: :.:.. : :.:::::: ...::
CCDS32 YSTGQPCVFIKMNRVINFYAG--ANQSMN-------------VTCAGKRDEDAENLGNFV
180 190 200 210
230 240 250 260 270 280
pF1KB8 YFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYS-E
.: ... . :.:.::::: .. .: :::.::.: :.: ..:. .::. . ::. . :
CCDS32 MFPANGN--IDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDE
220 230 240 250 260 270
290 300
pF1KB8 KDRFQGRFDVKIEVKS
.:.: :: :...
CCDS32 RDKFAGRVAFKLRINKT
280 290
>>CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX (357 aa)
initn: 635 init1: 279 opt: 476 Z-score: 581.2 bits: 115.8 E(32554): 4.7e-26
Smith-Waterman score: 625; 34.7% identity (65.3% similar) in 308 aa overlap (4-300:73-356)
10 20
pF1KB8 MARGKAKEEGS--WKK------FIWNSEKKEFL
:... :. :.: ..:. :.. ::
CCDS48 ARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFL
50 60 70 80 90 100
30 40 50 60 70 80
pF1KB8 GRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQK
.::: :: :::.: .::. ::... . ...:::: . ::. .:: :::. : ..
CCDS48 ARTGQSWSLILLIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHS
110 120 130 140 150 160
90 100 110 120 130 140
pF1KB8 TEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGE
...: ..: ... ::... ::. :.:: :.. . :: : : :... .
CCDS48 LNFNFNVSEPDTWQHYVISLNGFLQGYNDSLQEEMNV--DC---PPGQYFIQDGNEDE-D
170 180 190 200 210
150 160 170 180 190 200
pF1KB8 RKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYN
.:.:.:: .: :::::.: :.::. :.:::..:.::..::.:. ::
CCDS48 KKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPELGD-------PV----
220 230 240 250 260
210 220 230 240 250 260
pF1KB8 PNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTN
:.: .: ...: . .. :. .: .: :.:::::::: . .: .::.:..::.
CCDS48 ----KVSCKVQRGDEND-IRSISYYP--ESASFDLRYYPYYGKLTHVNYTSPLVAMHFTD
270 280 290 300 310
270 280 290 300
pF1KB8 LTMDTEIRIECKAYGEN-IGYSEKDRFQGR--FDVKIEVKS
.. . . ..:. :.. :. .::: :: : ..::
CCDS48 VVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
320 330 340 350
>>CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX (353 aa)
initn: 557 init1: 208 opt: 393 Z-score: 480.3 bits: 97.2 E(32554): 2e-20
Smith-Waterman score: 592; 34.1% identity (64.6% similar) in 308 aa overlap (4-300:73-352)
10 20
pF1KB8 MARGKAKEEGS--WKK------FIWNSEKKEFL
:... :. :.: ..:. :.. ::
CCDS14 ARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFL
50 60 70 80 90 100
30 40 50 60 70 80
pF1KB8 GRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQK
.::: :::.: .::. ::... . ...:::: . ::. .:: :::. : ..
CCDS14 ARTG----LILLIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHS
110 120 130 140 150
90 100 110 120 130 140
pF1KB8 TEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGE
...: ..: ... ::... ::. :.:: :.. . :: : : :... .
CCDS14 LNFNFNVSEPDTWQHYVISLNGFLQGYNDSLQEEMNV--DC---PPGQYFIQDGNEDE-D
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB8 RKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYN
.:.:.:: .: :::::.: :.::. :.:::..:.::..::.:. ::
CCDS14 KKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPELGD-------PV----
220 230 240 250 260
210 220 230 240 250 260
pF1KB8 PNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTN
:.: .: ...: . .. :. .: .: :.:::::::: . .: .::.:..::.
CCDS14 ----KVSCKVQRGDEND-IRSISYYP--ESASFDLRYYPYYGKLTHVNYTSPLVAMHFTD
270 280 290 300 310
270 280 290 300
pF1KB8 LTMDTEIRIECKAYGEN-IGYSEKDRFQGR--FDVKIEVKS
.. . . ..:. :.. :. .::: :: : ..::
CCDS14 VVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
320 330 340 350
>>CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 (291 aa)
initn: 477 init1: 194 opt: 389 Z-score: 476.8 bits: 96.2 E(32554): 3.1e-20
Smith-Waterman score: 522; 30.1% identity (61.8% similar) in 306 aa overlap (4-302:11-290)
10 20 30 40 50
pF1KB8 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGT
:. :: .... :: . ..:::: . : : :.:: :: ..:.:
CCDS95 MAALQEKKTCGQRMEE--FQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALC
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 IQVMLLTISEFKPTYQDRVAPPGLTQIPQI---QKTEISFRPNDPKSYEAYVLNIVRFLE
. :.. :.. . : :::.. ::.: :.. . :: . .: ... . .. ::
CCDS95 LYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 KYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYK
:. .::.:.. .: . .: .: . :.: . : ::::: : ..:..
CCDS95 GYSPAAQEDSI---NCTSEQYFFQE--SFRAPNHTKFSCKFTADMLQNCSGLADPNFGFE
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 EGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGN---V
:::::.:::.::.. : :. : .. :.:. :. .. .:. :
CCDS95 EGKPCFIIKMNRIVKFLPS---------------NGSAPRVDCAFL-DQPRE-LGQPLQV
180 190 200 210
230 240 250 260 270 280
pF1KB8 EYFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSE
.:. ... : :.:.::::: ::.: .::.:... :. ..:. : ::...:.. ...
CCDS95 KYYPPNGT--FSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNN
220 230 240 250 260 270
290 300
pF1KB8 -KDRFQGRFDVKIEVKS
.: ..:. . :....
CCDS95 PHDPYEGKVEFKLKIEK
280 290
>>CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 (279 aa)
initn: 580 init1: 241 opt: 317 Z-score: 389.5 bits: 80.0 E(32554): 2.3e-15
Smith-Waterman score: 603; 36.6% identity (60.4% similar) in 298 aa overlap (12-303:16-279)
10 20 30 40 50
pF1KB8 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQV
:: ::.: ::::::. :: :::::..::: ::..: :. :
CCDS31 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 MLLTISEFKPTYQDRVAPPGLTQIPQ-IQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDS
:: :... : :.:.. ::: .:. . : .: .:: :: .:. .. .::. :
CCDS31 MLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 AQRDDMIFEDCGDVPSEPKERGDFNHERGERKV-CRFKLEWLGNCSGLNDETYGYKEGKP
:.. . : : : . ...: : :.: . : :::.:: .::..:.:
CCDS31 EQKNLTV---CPD--------GALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNP
130 140 150 160
180 190 200 210 220 230
pF1KB8 CIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYFGLGN
::..:.::..:.:: : : ..:..: .:: .:. . :.
CCDS31 CILVKMNRIIGLKP--------EGVPR---------IDCVSK-NEDIPNVAVYPHNGM--
170 180 190 200
240 250 260 270 280 290
pF1KB8 SPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDT--EIRIECKAYGE-NI-GYSEKDR
. :.:.::::: :. :::::.::: . .: :. .::: : :. . ...:.
CCDS31 ---IDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDK
210 220 230 240 250 260
300
pF1KB8 FQGRFDVKIEVKS
: :: :: ...
CCDS31 FLGRVMFKITARA
270
303 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:19:27 2016 done: Fri Nov 4 10:19:28 2016
Total Scan time: 2.360 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]