FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8175, 501 aa
  1>>>pF1KB8175 501 - 501 aa - 501 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8396+/-0.000371; mu= 12.4159+/- 0.023
 mean_var=123.5313+/-24.275, 0's: 0 Z-trim(116.0): 31  B-trim: 62 in 1/56
 Lambda= 0.115395
 statistics sampled from 26893 (26922) to 26893 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.316), width:  16
 Scan time:  8.740

The best scores are:                                      opt bits E(85289)
NP_006793 (OMIM: 605596) splicing factor 3A subuni ( 501) 3351 569.2 9.9e-162
NP_001307759 (OMIM: 605596) splicing factor 3A sub ( 448) 2696 460.1 6.1e-129


>>NP_006793 (OMIM: 605596) splicing factor 3A subunit 3   (501 aa)
 initn: 3351 init1: 3351 opt: 3351  Z-score: 3024.6  bits: 569.2 E(85289): 9.9e-162
Smith-Waterman score: 3351; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)

               10        20        30        40        50        60
pF1KB8 METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 YDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKERKNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKERKNA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 EYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWPKETSSALTHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWPKETSSALTHA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 GAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 FAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEEREEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEEREEEE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 EEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASERWQPDTEEEYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASERWQPDTEEEYE
              430       440       450       460       470       480

              490       500 
pF1KB8 DSSGNVVNKKTYEDLKRQGLL
       :::::::::::::::::::::
NP_006 DSSGNVVNKKTYEDLKRQGLL
              490       500 

>>NP_001307759 (OMIM: 605596) splicing factor 3A subunit  (448 aa)
 initn: 2686 init1: 2686 opt: 2696  Z-score: 2435.9  bits: 460.1 E(85289): 6.1e-129
Smith-Waterman score: 2875; 89.4% identity (89.4% similar) in 501 aa overlap (1-501:1-448)

               10        20        30        40        50        60
pF1KB8 METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::            
NP_001 METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQD------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB8 YDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENP
                                                :::::::::::::::::::
NP_001 -----------------------------------------ICVPMSVEFEELLKARENP
                                                50        60       

              130       140       150       160       170       180
pF1KB8 SEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKERKNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKERKNA
        70        80        90       100       110       120       

              190       200       210       220       230       240
pF1KB8 EYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWPKETSSALTHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWPKETSSALTHA
       130       140       150       160       170       180       

              250       260       270       280       290       300
pF1KB8 GAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSL
       190       200       210       220       230       240       

              310       320       330       340       350       360
pF1KB8 FAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEEREEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEEREEEE
       250       260       270       280       290       300       

              370       380       390       400       410       420
pF1KB8 EEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPK
       310       320       330       340       350       360       

              430       440       450       460       470       480
pF1KB8 AFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASERWQPDTEEEYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASERWQPDTEEEYE
       370       380       390       400       410       420       

              490       500 
pF1KB8 DSSGNVVNKKTYEDLKRQGLL
       :::::::::::::::::::::
NP_001 DSSGNVVNKKTYEDLKRQGLL
       430       440        




501 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:15:59 2016 done: Fri Nov  4 10:16:00 2016
 Total Scan time:  8.740 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]