Result of FASTA (omim) for
pF1KB8171
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8171, 557 aa
1>>>pF1KB8171 557 - 557 aa - 557 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0975+/-0.000465; mu= 14.0676+/- 0.028
mean_var=75.9437+/-15.549, 0's: 0 Z-trim(108.7): 125 B-trim: 146 in 1/50
Lambda= 0.147173
statistics sampled from 16694 (16827) to 16694 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.544), E-opt: 0.2 (0.197), width: 16
Scan time: 7.190
The best scores are: opt bits E(85289)
NP_570720 (OMIM: 604208) copine-4 isoform 2 [Homo ( 557) 3756 807.7 0
XP_016861182 (OMIM: 604208) PREDICTED: copine-4 is ( 575) 3756 807.7 0
NP_702907 (OMIM: 604208) copine-4 isoform 1 [Homo ( 575) 3756 807.7 0
NP_001276041 (OMIM: 604208) copine-4 isoform 1 [Ho ( 575) 3756 807.7 0
XP_011510709 (OMIM: 604208) PREDICTED: copine-4 is ( 444) 2993 645.7 8.9e-185
XP_011510710 (OMIM: 604208) PREDICTED: copine-4 is ( 444) 2993 645.7 8.9e-185
XP_011510708 (OMIM: 604208) PREDICTED: copine-4 is ( 444) 2993 645.7 8.9e-185
XP_016861183 (OMIM: 604208) PREDICTED: copine-4 is ( 434) 2950 636.6 4.9e-182
NP_705900 (OMIM: 605689) copine-7 isoform a [Homo ( 558) 2625 567.6 3.6e-161
XP_011521302 (OMIM: 605689) PREDICTED: copine-7 is ( 595) 2490 538.9 1.6e-152
XP_016878629 (OMIM: 605689) PREDICTED: copine-7 is ( 599) 2474 535.5 1.7e-151
NP_006023 (OMIM: 605688) copine-6 isoform 2 [Homo ( 557) 2363 512.0 2e-144
XP_005268273 (OMIM: 605688) PREDICTED: copine-6 is ( 557) 2363 512.0 2e-144
NP_001267487 (OMIM: 605688) copine-6 isoform 1 [Ho ( 612) 2363 512.0 2.2e-144
XP_016861184 (OMIM: 604208) PREDICTED: copine-4 is ( 417) 2250 487.9 2.6e-137
NP_055242 (OMIM: 605689) copine-7 isoform b [Homo ( 633) 2186 474.4 4.6e-133
XP_016878628 (OMIM: 605689) PREDICTED: copine-7 is ( 637) 2186 474.4 4.7e-133
XP_016861185 (OMIM: 604208) PREDICTED: copine-4 is ( 306) 2067 449.0 9.8e-126
XP_011521303 (OMIM: 605689) PREDICTED: copine-7 is ( 527) 2051 445.7 1.7e-124
XP_016878627 (OMIM: 605689) PREDICTED: copine-7 is ( 670) 2051 445.8 2.1e-124
XP_016869434 (OMIM: 604207) PREDICTED: copine-3 is ( 537) 2035 442.3 1.8e-123
NP_003900 (OMIM: 604207) copine-3 [Homo sapiens] ( 537) 2035 442.3 1.8e-123
XP_005251150 (OMIM: 604207) PREDICTED: copine-3 is ( 537) 2035 442.3 1.8e-123
NP_689940 (OMIM: 604206) copine-2 [Homo sapiens] ( 548) 1956 425.6 2e-118
NP_690904 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1859 405.0 3.2e-112
NP_690902 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1859 405.0 3.2e-112
NP_690905 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1859 405.0 3.2e-112
NP_690903 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1859 405.0 3.2e-112
NP_003906 (OMIM: 604205) copine-1 isoform b [Homo ( 542) 1859 405.0 3.2e-112
NP_001185792 (OMIM: 604205) copine-1 isoform c [Ho ( 536) 1840 400.9 5.2e-111
XP_005268274 (OMIM: 605688) PREDICTED: copine-6 is ( 382) 1741 379.8 8.2e-105
NP_065990 (OMIM: 604209) copine-5 isoform a [Homo ( 593) 1472 322.8 1.9e-87
XP_005249304 (OMIM: 604209) PREDICTED: copine-5 is ( 610) 1467 321.7 4.1e-87
XP_016878630 (OMIM: 605689) PREDICTED: copine-7 is ( 344) 1435 314.9 2.7e-85
XP_011513071 (OMIM: 604209) PREDICTED: copine-5 is ( 653) 1371 301.4 5.9e-81
XP_016866628 (OMIM: 604209) PREDICTED: copine-5 is ( 522) 1366 300.3 1e-80
XP_011513073 (OMIM: 604209) PREDICTED: copine-5 is ( 632) 1366 300.3 1.2e-80
XP_011513072 (OMIM: 604209) PREDICTED: copine-5 is ( 632) 1366 300.3 1.2e-80
XP_011513070 (OMIM: 604209) PREDICTED: copine-5 is ( 670) 1366 300.3 1.3e-80
XP_011513075 (OMIM: 604209) PREDICTED: copine-5 is ( 473) 1320 290.5 8e-78
XP_011513074 (OMIM: 604209) PREDICTED: copine-5 is ( 543) 1192 263.3 1.4e-69
NP_001300947 (OMIM: 604209) copine-5 isoform c [Ho ( 301) 1015 225.7 1.7e-58
XP_011513077 (OMIM: 604209) PREDICTED: copine-5 is ( 361) 914 204.2 5.6e-52
NP_001300948 (OMIM: 604209) copine-5 isoform d [Ho ( 243) 791 178.1 2.9e-44
NP_001300949 (OMIM: 604209) copine-5 isoform d [Ho ( 243) 791 178.1 2.9e-44
NP_001300946 (OMIM: 604209) copine-5 isoform b [Ho ( 140) 310 75.9 9.7e-14
NP_002730 (OMIM: 176980,605361) protein kinase C g ( 697) 202 53.2 3.3e-06
NP_001303258 (OMIM: 176980,605361) protein kinase ( 710) 202 53.2 3.3e-06
NP_997700 (OMIM: 176970) protein kinase C beta typ ( 671) 196 51.9 7.6e-06
NP_002729 (OMIM: 176970) protein kinase C beta typ ( 673) 196 51.9 7.7e-06
>>NP_570720 (OMIM: 604208) copine-4 isoform 2 [Homo sapi (557 aa)
initn: 3756 init1: 3756 opt: 3756 Z-score: 4312.3 bits: 807.7 E(85289): 0
Smith-Waterman score: 3756; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KB8 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 VDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 IVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 IVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 IFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 FIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 MGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 MGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 FGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 AKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 QMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 QMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGI
490 500 510 520 530 540
550
pF1KB8 KPKCSSEMYESSRTLAP
:::::::::::::::::
NP_570 KPKCSSEMYESSRTLAP
550
>>XP_016861182 (OMIM: 604208) PREDICTED: copine-4 isofor (575 aa)
initn: 3756 init1: 3756 opt: 3756 Z-score: 4312.1 bits: 807.7 E(85289): 0
Smith-Waterman score: 3756; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:19-575)
10 20 30 40
pF1KB8 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVEPSSSESIKRRAGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 NGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 ARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDP
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 DRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGT
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB8 VILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKAL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB8 VAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB8 PKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASH
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB8 LPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKS
490 500 510 520 530 540
530 540 550
pF1KB8 VLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
:::::::::::::::::::::::::::::::::::
XP_016 VLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
550 560 570
>>NP_702907 (OMIM: 604208) copine-4 isoform 1 [Homo sapi (575 aa)
initn: 3756 init1: 3756 opt: 3756 Z-score: 4312.1 bits: 807.7 E(85289): 0
Smith-Waterman score: 3756; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:19-575)
10 20 30 40
pF1KB8 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
::::::::::::::::::::::::::::::::::::::::::
NP_702 MAVEPSSSESIKRRAGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 NGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 NGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 ARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 ARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDP
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 DRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 DRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGT
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB8 VILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 VILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKAL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB8 VAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 VAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB8 PKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 PKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASH
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB8 LPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_702 LPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKS
490 500 510 520 530 540
530 540 550
pF1KB8 VLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
:::::::::::::::::::::::::::::::::::
NP_702 VLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
550 560 570
>>NP_001276041 (OMIM: 604208) copine-4 isoform 1 [Homo s (575 aa)
initn: 3756 init1: 3756 opt: 3756 Z-score: 4312.1 bits: 807.7 E(85289): 0
Smith-Waterman score: 3756; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:19-575)
10 20 30 40
pF1KB8 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVEPSSSESIKRRAGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 NGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 ARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDP
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 DRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGT
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB8 VILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKAL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB8 VAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB8 PKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASH
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB8 LPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKS
490 500 510 520 530 540
530 540 550
pF1KB8 VLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
:::::::::::::::::::::::::::::::::::
NP_001 VLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
550 560 570
>>XP_011510709 (OMIM: 604208) PREDICTED: copine-4 isofor (444 aa)
initn: 2993 init1: 2993 opt: 2993 Z-score: 3438.3 bits: 645.7 E(85289): 8.9e-185
Smith-Waterman score: 2993; 100.0% identity (100.0% similar) in 444 aa overlap (114-557:1-444)
90 100 110 120 130 140
pF1KB8 YFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSI
::::::::::::::::::::::::::::::
XP_011 MECTLGQIVSQRKLSKSLLKHGNTAGKSSI
10 20 30
150 160 170 180 190 200
pF1KB8 TVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNL
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB8 SPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQW
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB8 ECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRN
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB8 SCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNE
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB8 DNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILT
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB8 DGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIV
340 350 360 370 380 390
510 520 530 540 550
pF1KB8 QFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
400 410 420 430 440
>>XP_011510710 (OMIM: 604208) PREDICTED: copine-4 isofor (444 aa)
initn: 2993 init1: 2993 opt: 2993 Z-score: 3438.3 bits: 645.7 E(85289): 8.9e-185
Smith-Waterman score: 2993; 100.0% identity (100.0% similar) in 444 aa overlap (114-557:1-444)
90 100 110 120 130 140
pF1KB8 YFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSI
::::::::::::::::::::::::::::::
XP_011 MECTLGQIVSQRKLSKSLLKHGNTAGKSSI
10 20 30
150 160 170 180 190 200
pF1KB8 TVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNL
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB8 SPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQW
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB8 ECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRN
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB8 SCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNE
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB8 DNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILT
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB8 DGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIV
340 350 360 370 380 390
510 520 530 540 550
pF1KB8 QFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
400 410 420 430 440
>>XP_011510708 (OMIM: 604208) PREDICTED: copine-4 isofor (444 aa)
initn: 2993 init1: 2993 opt: 2993 Z-score: 3438.3 bits: 645.7 E(85289): 8.9e-185
Smith-Waterman score: 2993; 100.0% identity (100.0% similar) in 444 aa overlap (114-557:1-444)
90 100 110 120 130 140
pF1KB8 YFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSI
::::::::::::::::::::::::::::::
XP_011 MECTLGQIVSQRKLSKSLLKHGNTAGKSSI
10 20 30
150 160 170 180 190 200
pF1KB8 TVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNL
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB8 SPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQW
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB8 ECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRN
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB8 SCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNE
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB8 DNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILT
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB8 DGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIV
340 350 360 370 380 390
510 520 530 540 550
pF1KB8 QFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
400 410 420 430 440
>>XP_016861183 (OMIM: 604208) PREDICTED: copine-4 isofor (434 aa)
initn: 2950 init1: 2950 opt: 2950 Z-score: 3389.2 bits: 636.6 E(85289): 4.9e-182
Smith-Waterman score: 2950; 100.0% identity (100.0% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KB8 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 IVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 MGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDM
::::::::::::::
XP_016 AKSASEETNTKEAS
430
>>NP_705900 (OMIM: 605689) copine-7 isoform a [Homo sapi (558 aa)
initn: 2636 init1: 2159 opt: 2625 Z-score: 3014.5 bits: 567.6 E(85289): 3.6e-161
Smith-Waterman score: 2625; 70.5% identity (89.6% similar) in 536 aa overlap (11-543:9-543)
10 20 30 40 50 60
pF1KB8 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFE
:: : : . .:: .:::::..:. . ::: :.: :: : : .:..::: .
NP_705 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ
10 20 30 40 50
70 80 90 100 110
pF1KB8 VDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGL--KEADFLGGMECTL
: ::::.:. ..::.::.::::.::::::::::::.: . . .:. .: ::::::::::
NP_705 VGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYD-THGPSGFSCQEDDFLGGMECTL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 GQIVSQRKLSKSLL-KHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDP
::::.:.:... :: : : .::::.::::::..:::. ::::.: ::::::::.::::::
NP_705 GQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 FLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNG
:::..:.::: :::.::::: :::.:.:..::::..:::: . : :::.:::.:: :
NP_705 FLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFL
::::::::..::.::. :.: :.::.:.::::: :...:::::.:.: :.:...:::
NP_705 KHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 DYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKM
:::::::::.:::::::::::::::::::::::.::::::::::::.::::::::::::
NP_705 DYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB8 FPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPII
: :.::::::::.: :::::::::: .. :: ::::::::::.:::..:::::::.::::
NP_705 FSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPII
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB8 QKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADF
.:::. :. : .: .::::.:::::::::.:::::::::::.::.::::.::::::::::
NP_705 SKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB8 SDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNG
.:::.::::::.::::.:::.:::::::::::..:.:::::::: ::::::.:::.::.
NP_705 TDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSH
480 490 500 510 520 530
540 550
pF1KB8 KGIKPKCSSEMYESSRTLAP
.:. :.
NP_705 RGLPPRSLGVPAGEASPGCTP
540 550
>>XP_011521302 (OMIM: 605689) PREDICTED: copine-7 isofor (595 aa)
initn: 2498 init1: 2021 opt: 2490 Z-score: 2859.1 bits: 538.9 E(85289): 1.6e-152
Smith-Waterman score: 2490; 69.6% identity (88.6% similar) in 516 aa overlap (11-523:9-523)
10 20 30 40 50 60
pF1KB8 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFE
:: : : . .:: .:::::..:. . ::: :.: :: : : .:..::: .
XP_011 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ
10 20 30 40 50
70 80 90 100 110
pF1KB8 VDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGL--KEADFLGGMECTL
: ::::.:. ..::.::.::::.::::::::::::.: . . .:. .: ::::::::::
XP_011 VGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYD-THGPSGFSCQEDDFLGGMECTL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 GQIVSQRKLSKSLL-KHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDP
::::.:.:... :: : : .::::.::::::..:::. ::::.: ::::::::.::::::
XP_011 GQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 FLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNG
:::..:.::: :::.::::: :::.:.:..::::..:::: . : :::.:::.:: :
XP_011 FLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFL
::::::::..::.::. :.: :.::.:.::::: :...:::::.:.: :.:...:::
XP_011 KHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 DYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKM
:::::::::.:::::::::::::::::::::::.::::::::::::.::::::::::::
XP_011 DYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB8 FPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPII
: :.::::::::.: :::::::::: .. :: ::::::::::.:::..:::::::.::::
XP_011 FSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPII
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB8 QKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADF
.:::. :. : .: .::::.:::::::::.:::::::::::.::.::::.::::::::::
XP_011 SKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB8 SDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNG
.:::.::::::.::::.:::.:::::::::::..:. : : ..
XP_011 TDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNQRTAQGAPGIHHAASPVAANLCDP
480 490 500 510 520 530
540 550
pF1KB8 KGIKPKCSSEMYESSRTLAP
XP_011 ARHAQHTRIPCGAGQVRAGRGPEAGGGVLQPQRPAPEKPGCPCRRGQPRLHTVKMWRA
540 550 560 570 580 590
557 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:13:22 2016 done: Fri Nov 4 10:13:23 2016
Total Scan time: 7.190 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]