FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8159, 140 aa
  1>>>pF1KB8159 140 - 140 aa - 140 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0736+/-0.000362; mu= 11.5390+/- 0.022
 mean_var=51.3750+/-10.514, 0's: 0 Z-trim(113.3): 13  B-trim: 625 in 1/48
 Lambda= 0.178936
 statistics sampled from 22554 (22566) to 22554 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.265), width:  16
 Scan time:  3.690

The best scores are:                                      opt bits E(85289)
NP_444252 (OMIM: 176590) profilin-2 isoform a [Hom ( 140)  963 256.2 1.3e-68
NP_002619 (OMIM: 176590) profilin-2 isoform b [Hom ( 140)  895 238.6 2.5e-63
NP_005013 (OMIM: 176610,614808) profilin-1 [Homo s ( 140)  605 163.7 8.6e-41
XP_016880250 (OMIM: 176610,614808) PREDICTED: prof ( 181)  473 129.7   2e-30
NP_001025057 (OMIM: 612812) profilin-3 [Homo sapie ( 137)  385 106.9   1e-23


>>NP_444252 (OMIM: 176590) profilin-2 isoform a [Homo sa  (140 aa)
 initn: 963 init1: 963 opt: 963  Z-score: 1352.8  bits: 256.2 E(85289): 1.3e-68
Smith-Waterman score: 963; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140)

               10        20        30        40        50        60
pF1KB8 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
               70        80        90       100       110       120

              130       140
pF1KB8 GGGLNKKAYSMAKYLRDSGF
       ::::::::::::::::::::
NP_444 GGGLNKKAYSMAKYLRDSGF
              130       140

>>NP_002619 (OMIM: 176590) profilin-2 isoform b [Homo sa  (140 aa)
 initn: 907 init1: 895 opt: 895  Z-score: 1258.0  bits: 238.6 E(85289): 2.5e-63
Smith-Waterman score: 895; 94.9% identity (97.1% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KB8 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
       ::::::::::::::::::::::::::::::::::::::::::::::::.::.::::::::
NP_002 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRALVIVMGKEGVH
               70        80        90       100       110       120

              130       140
pF1KB8 GGGLNKKAYSMAKYLRDSGF
       :: :::::: .: ::: :  
NP_002 GGTLNKKAYELALYLRRSDV
              130       140

>>NP_005013 (OMIM: 176610,614808) profilin-1 [Homo sapie  (140 aa)
 initn: 619 init1: 605 opt: 605  Z-score: 853.4  bits: 163.7 E(85289): 8.6e-41
Smith-Waterman score: 605; 61.4% identity (83.6% similar) in 140 aa overlap (1-140:1-140)

               10        20        30        40        50        60
pF1KB8 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
       ::::..:.:::: :: ::.:::::: :.  ::::. : .: .::: :. ..::::: .:.
NP_005 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
       .::::::..:::::::::  ::. .::.:::: :: ::.::.: .. ..::..:::::::
NP_005 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH
               70        80        90       100       110       120

              130       140
pF1KB8 GGGLNKKAYSMAKYLRDSGF
       :: .::: : ::..:: : .
NP_005 GGLINKKCYEMASHLRRSQY
              130       140

>>XP_016880250 (OMIM: 176610,614808) PREDICTED: profilin  (181 aa)
 initn: 487 init1: 473 opt: 473  Z-score: 667.4  bits: 129.7 E(85289): 2e-30
Smith-Waterman score: 473; 61.1% identity (83.3% similar) in 108 aa overlap (1-108:1-108)

               10        20        30        40        50        60
pF1KB8 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
       ::::..:.:::: :: ::.:::::: :.  ::::. : .: .::: :. ..::::: .:.
XP_016 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
       .::::::..:::::::::  ::. .::.:::: :: ::.::.: .. .            
XP_016 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKSEFLSLTLPLAP
               70        80        90       100       110       120

              130       140                                        
pF1KB8 GGGLNKKAYSMAKYLRDSGF                                        
                                                                   
XP_016 RSLMYRLLVILRVLFCVIPQHEGSQTSIVFLVCWMLEHGIVPPFCLSSSSCNSKLLNCIT
              130       140       150       160       170       180

>>NP_001025057 (OMIM: 612812) profilin-3 [Homo sapiens]   (137 aa)
 initn: 360 init1: 238 opt: 385  Z-score: 546.6  bits: 106.9 E(85289): 1e-23
Smith-Waterman score: 385; 41.0% identity (71.2% similar) in 139 aa overlap (1-139:1-136)

               10        20        30        40        50        60
pF1KB8 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
       :. :. :.. .. :   ...::::. : . :::.  ::.. .:.: :. ...: ::. :.
NP_001 MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
         ::..:...: :::: : ..:: ..: :::   :  .  : :::: :.:. .::..:::
NP_001 QAGLSVGGRRCCVIRDHLLAEGDGVLDARTK---GLDARAVCVGRAPRALLVLMGRRGVH
               70        80        90          100       110       

              130       140
pF1KB8 GGGLNKKAYSMAKYLRDSGF
       :: ::: .. . . :: .: 
NP_001 GGILNKTVHELIRGLRMQGA
       120       130       




140 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:06:54 2016 done: Fri Nov  4 10:06:55 2016
 Total Scan time:  3.690 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]