Result of FASTA (omim) for
pF1KB8155
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8155, 460 aa
1>>>pF1KB8155 460 - 460 aa - 460 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5537+/-0.000298; mu= 5.0713+/- 0.019
mean_var=194.2526+/-38.917, 0's: 0 Z-trim(123.8): 411 B-trim: 0 in 0/59
Lambda= 0.092022
statistics sampled from 43976 (44389) to 43976 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.813), E-opt: 0.2 (0.52), width: 16
Scan time: 9.650
The best scores are: opt bits E(85289)
NP_009052 (OMIM: 600380) oxysterols receptor LXR-b ( 461) 3131 427.5 3.7e-119
NP_001243576 (OMIM: 600380) oxysterols receptor LX ( 364) 1955 271.3 3.1e-72
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 1234 175.6 2.2e-43
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 1234 175.6 2.2e-43
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 1234 175.6 2.2e-43
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 1234 175.6 2.2e-43
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 1234 175.6 2.2e-43
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 1234 175.6 2.2e-43
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 1234 175.6 2.3e-43
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 1234 175.6 2.3e-43
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 1234 175.6 2.3e-43
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 1234 175.6 2.3e-43
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 1234 175.6 2.3e-43
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 1234 175.6 2.3e-43
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 1234 175.6 2.3e-43
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 1234 175.7 2.4e-43
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 1234 175.7 2.4e-43
XP_011518109 (OMIM: 602423) PREDICTED: oxysterols ( 313) 1228 174.7 3.1e-43
XP_005252773 (OMIM: 602423) PREDICTED: oxysterols ( 313) 1228 174.7 3.1e-43
XP_005252772 (OMIM: 602423) PREDICTED: oxysterols ( 358) 1228 174.8 3.4e-43
XP_011518110 (OMIM: 602423) PREDICTED: oxysterols ( 235) 1216 173.1 7.4e-43
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols ( 332) 830 121.9 2.6e-27
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols ( 323) 822 120.8 5.3e-27
XP_005252775 (OMIM: 602423) PREDICTED: oxysterols ( 253) 760 112.5 1.3e-24
XP_011518108 (OMIM: 602423) PREDICTED: oxysterols ( 342) 760 112.6 1.7e-24
NP_001123573 (OMIM: 602423) oxysterols receptor LX ( 387) 760 112.7 1.8e-24
XP_005252770 (OMIM: 602423) PREDICTED: oxysterols ( 387) 760 112.7 1.8e-24
NP_001165290 (OMIM: 600409) peroxisome proliferato ( 402) 516 80.3 1.1e-14
XP_016866461 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_016866462 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_016866463 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_005249250 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_011513011 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_006715186 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_011513009 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_016866460 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_006715183 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
XP_011513012 (OMIM: 600409) PREDICTED: peroxisome ( 441) 516 80.3 1.1e-14
NP_006229 (OMIM: 600409) peroxisome proliferator-a ( 441) 516 80.3 1.1e-14
NP_001165289 (OMIM: 600409) peroxisome proliferato ( 441) 516 80.3 1.1e-14
XP_011537344 (OMIM: 603826,617049) PREDICTED: bile ( 280) 468 73.8 6.6e-13
NP_005114 (OMIM: 603826,617049) bile acid receptor ( 472) 468 74.0 1e-12
NP_001193921 (OMIM: 603826,617049) bile acid recep ( 482) 468 74.0 1e-12
XP_016880409 (OMIM: 180240,612376) PREDICTED: reti ( 343) 453 71.9 3.1e-12
XP_011537019 (OMIM: 601529) PREDICTED: nuclear rec ( 507) 456 72.4 3.2e-12
NP_001138774 (OMIM: 180240,612376) retinoic acid r ( 365) 453 71.9 3.3e-12
XP_006719782 (OMIM: 603826,617049) PREDICTED: bile ( 284) 450 71.4 3.5e-12
XP_011523398 (OMIM: 180240,612376) PREDICTED: reti ( 404) 453 71.9 3.5e-12
NP_001019980 (OMIM: 180240,612376) retinoic acid r ( 457) 453 72.0 3.9e-12
XP_005257611 (OMIM: 180240,612376) PREDICTED: reti ( 462) 453 72.0 3.9e-12
>>NP_009052 (OMIM: 600380) oxysterols receptor LXR-beta (461 aa)
initn: 1898 init1: 1898 opt: 3131 Z-score: 2260.3 bits: 427.5 E(85289): 3.7e-119
Smith-Waterman score: 3131; 99.8% identity (99.8% similar) in 461 aa overlap (1-460:1-461)
10 20 30 40 50 60
pF1KB8 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQ-ESQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_009 RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR
370 380 390 400 410 420
420 430 440 450 460
pF1KB8 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::::::::::::::::
NP_009 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
430 440 450 460
>>NP_001243576 (OMIM: 600380) oxysterols receptor LXR-be (364 aa)
initn: 2329 init1: 1898 opt: 1955 Z-score: 1418.0 bits: 271.3 E(85289): 3.1e-72
Smith-Waterman score: 2194; 78.7% identity (78.7% similar) in 461 aa overlap (1-460:1-364)
10 20 30 40 50 60
pF1KB8 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
:
NP_001 ---------------G--------------------------------------------
130 140 150 160 170
pF1KB8 RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQ-ESQS
::::::::::::::::: ::::
NP_001 --------------------------------------VLSEEQIRKKKIRKQQQQESQS
70 80
180 190 200 210 220 230
pF1KB8 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB8 RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ
150 160 170 180 190 200
300 310 320 330 340 350
pF1KB8 IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM
210 220 230 240 250 260
360 370 380 390 400 410
pF1KB8 RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR
270 280 290 300 310 320
420 430 440 450 460
pF1KB8 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::::::::::::::::
NP_001 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
330 340 350 360
>>XP_006718179 (OMIM: 602423) PREDICTED: oxysterols rece (402 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 900.0 bits: 175.6 E(85289): 2.2e-43
Smith-Waterman score: 1811; 69.3% identity (84.6% similar) in 397 aa overlap (64-460:30-402)
40 50 60 70 80 90
pF1KB8 GPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDK
.: : .::::::::::::.::: :::::
XP_006 MPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDK
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 ASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAG
::::::::::::::::::::::..:. .: :..:: : ::..::::::.::::::..::
XP_006 ASGFHYNVLSCEGCKGFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB8 MREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGE
:::.::::::::: ::...:..:. .. : :..:: : :
XP_006 MREECVLSEEQIRLKKLKRQEEEQAHATSLP--PRASSP----PQILP------------
120 130 140 150
220 230 240 250 260 270
pF1KB8 GEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTEL
::. : ::..::::: :::.:::::. .:::::.. ::.::.::::::::::::
XP_006 ----QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTEL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 AIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFT
::.:::::::::::.::::::.:::::::::.:.::.:::::.:::: .: :::::::.
XP_006 AIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 YSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEA
:...:: .:::::::::::::::::: .: :.:::.::::::.::::::::::. .::
XP_006 YNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVER
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 LQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
::. ::::: .:. :..:.:.: :::::::::::::::::::::::::::::::::::::
XP_006 LQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
340 350 360 370 380 390
460
pF1KB8 EIWDVHE
:::::::
XP_006 EIWDVHE
400
>>NP_001123574 (OMIM: 602423) oxysterols receptor LXR-al (402 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 900.0 bits: 175.6 E(85289): 2.2e-43
Smith-Waterman score: 1811; 69.3% identity (84.6% similar) in 397 aa overlap (64-460:30-402)
40 50 60 70 80 90
pF1KB8 GPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDK
.: : .::::::::::::.::: :::::
NP_001 MPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDK
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 ASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAG
::::::::::::::::::::::..:. .: :..:: : ::..::::::.::::::..::
NP_001 ASGFHYNVLSCEGCKGFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB8 MREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGE
:::.::::::::: ::...:..:. .. : :..:: : :
NP_001 MREECVLSEEQIRLKKLKRQEEEQAHATSLP--PRASSP----PQILP------------
120 130 140 150
220 230 240 250 260 270
pF1KB8 GEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTEL
::. : ::..::::: :::.:::::. .:::::.. ::.::.::::::::::::
NP_001 ----QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTEL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 AIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFT
::.:::::::::::.::::::.:::::::::.:.::.:::::.:::: .: :::::::.
NP_001 AIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 YSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEA
:...:: .:::::::::::::::::: .: :.:::.::::::.::::::::::. .::
NP_001 YNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVER
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 LQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
::. ::::: .:. :..:.:.: :::::::::::::::::::::::::::::::::::::
NP_001 LQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
340 350 360 370 380 390
460
pF1KB8 EIWDVHE
:::::::
NP_001 EIWDVHE
400
>>XP_006718178 (OMIM: 602423) PREDICTED: oxysterols rece (402 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 900.0 bits: 175.6 E(85289): 2.2e-43
Smith-Waterman score: 1811; 69.3% identity (84.6% similar) in 397 aa overlap (64-460:30-402)
40 50 60 70 80 90
pF1KB8 GPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDK
.: : .::::::::::::.::: :::::
XP_006 MPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDK
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 ASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAG
::::::::::::::::::::::..:. .: :..:: : ::..::::::.::::::..::
XP_006 ASGFHYNVLSCEGCKGFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB8 MREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGE
:::.::::::::: ::...:..:. .. : :..:: : :
XP_006 MREECVLSEEQIRLKKLKRQEEEQAHATSLP--PRASSP----PQILP------------
120 130 140 150
220 230 240 250 260 270
pF1KB8 GEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTEL
::. : ::..::::: :::.:::::. .:::::.. ::.::.::::::::::::
XP_006 ----QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTEL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 AIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFT
::.:::::::::::.::::::.:::::::::.:.::.:::::.:::: .: :::::::.
XP_006 AIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 YSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEA
:...:: .:::::::::::::::::: .: :.:::.::::::.::::::::::. .::
XP_006 YNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVER
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 LQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
::. ::::: .:. :..:.:.: :::::::::::::::::::::::::::::::::::::
XP_006 LQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
340 350 360 370 380 390
460
pF1KB8 EIWDVHE
:::::::
XP_006 EIWDVHE
400
>>XP_005252767 (OMIM: 602423) PREDICTED: oxysterols rece (402 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 900.0 bits: 175.6 E(85289): 2.2e-43
Smith-Waterman score: 1811; 69.3% identity (84.6% similar) in 397 aa overlap (64-460:30-402)
40 50 60 70 80 90
pF1KB8 GPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDK
.: : .::::::::::::.::: :::::
XP_005 MPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDK
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 ASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAG
::::::::::::::::::::::..:. .: :..:: : ::..::::::.::::::..::
XP_005 ASGFHYNVLSCEGCKGFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB8 MREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGE
:::.::::::::: ::...:..:. .. : :..:: : :
XP_005 MREECVLSEEQIRLKKLKRQEEEQAHATSLP--PRASSP----PQILP------------
120 130 140 150
220 230 240 250 260 270
pF1KB8 GEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTEL
::. : ::..::::: :::.:::::. .:::::.. ::.::.::::::::::::
XP_005 ----QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTEL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 AIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFT
::.:::::::::::.::::::.:::::::::.:.::.:::::.:::: .: :::::::.
XP_005 AIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 YSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEA
:...:: .:::::::::::::::::: .: :.:::.::::::.::::::::::. .::
XP_005 YNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVER
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 LQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
::. ::::: .:. :..:.:.: :::::::::::::::::::::::::::::::::::::
XP_005 LQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
340 350 360 370 380 390
460
pF1KB8 EIWDVHE
:::::::
XP_005 EIWDVHE
400
>>XP_005252766 (OMIM: 602423) PREDICTED: oxysterols rece (402 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 900.0 bits: 175.6 E(85289): 2.2e-43
Smith-Waterman score: 1811; 69.3% identity (84.6% similar) in 397 aa overlap (64-460:30-402)
40 50 60 70 80 90
pF1KB8 GPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDK
.: : .::::::::::::.::: :::::
XP_005 MPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDK
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 ASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAG
::::::::::::::::::::::..:. .: :..:: : ::..::::::.::::::..::
XP_005 ASGFHYNVLSCEGCKGFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB8 MREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGE
:::.::::::::: ::...:..:. .. : :..:: : :
XP_005 MREECVLSEEQIRLKKLKRQEEEQAHATSLP--PRASSP----PQILP------------
120 130 140 150
220 230 240 250 260 270
pF1KB8 GEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTEL
::. : ::..::::: :::.:::::. .:::::.. ::.::.::::::::::::
XP_005 ----QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTEL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 AIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFT
::.:::::::::::.::::::.:::::::::.:.::.:::::.:::: .: :::::::.
XP_005 AIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 YSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEA
:...:: .:::::::::::::::::: .: :.:::.::::::.::::::::::. .::
XP_005 YNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVER
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 LQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
::. ::::: .:. :..:.:.: :::::::::::::::::::::::::::::::::::::
XP_005 LQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
340 350 360 370 380 390
460
pF1KB8 EIWDVHE
:::::::
XP_005 EIWDVHE
400
>>XP_016872547 (OMIM: 602423) PREDICTED: oxysterols rece (402 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 900.0 bits: 175.6 E(85289): 2.2e-43
Smith-Waterman score: 1811; 69.3% identity (84.6% similar) in 397 aa overlap (64-460:30-402)
40 50 60 70 80 90
pF1KB8 GPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDK
.: : .::::::::::::.::: :::::
XP_016 MPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDK
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 ASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAG
::::::::::::::::::::::..:. .: :..:: : ::..::::::.::::::..::
XP_016 ASGFHYNVLSCEGCKGFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB8 MREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGE
:::.::::::::: ::...:..:. .. : :..:: : :
XP_016 MREECVLSEEQIRLKKLKRQEEEQAHATSLP--PRASSP----PQILP------------
120 130 140 150
220 230 240 250 260 270
pF1KB8 GEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTEL
::. : ::..::::: :::.:::::. .:::::.. ::.::.::::::::::::
XP_016 ----QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTEL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 AIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFT
::.:::::::::::.::::::.:::::::::.:.::.:::::.:::: .: :::::::.
XP_016 AIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 YSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEA
:...:: .:::::::::::::::::: .: :.:::.::::::.::::::::::. .::
XP_016 YNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVER
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 LQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
::. ::::: .:. :..:.:.: :::::::::::::::::::::::::::::::::::::
XP_016 LQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLS
340 350 360 370 380 390
460
pF1KB8 EIWDVHE
:::::::
XP_016 EIWDVHE
400
>>XP_006718175 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 899.4 bits: 175.6 E(85289): 2.3e-43
Smith-Waterman score: 1835; 62.8% identity (78.9% similar) in 460 aa overlap (4-460:13-447)
10 20 30 40 50
pF1KB8 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTV-KEEGPEPWPGGPDPDVPGTD
: :... :: . : ..: . .::. : .: : : .
XP_006 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGV-GLE
10 20 30 40 50
60 70 80 90 100
pF1KB8 EASSACSTDWVIP--DPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCK
: . . : .: : .::::::::::::.::: ::::::::::::::::::::
XP_006 AAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 GFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKK
:::::::..:. .: :..:: : ::..::::::.::::::..:::::.::::::::: :
XP_006 GFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 KIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQ
:...:..:. .. : :..:: : : ::. : ::.
XP_006 KLKRQEEEQAHATSLP--PRASSP----PQILP----------------QLSPEQLGMIE
180 190 200 210
230 240 250 260 270 280
pF1KB8 QLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQV
.::::: :::.:::::. .:::::.. ::.::.::::::::::::::.:::::::::::.
XP_006 KLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQL
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB8 PGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEF
::::::.:::::::::.:.::.:::::.:::: .: :::::::.:...:: .:::::::
XP_006 PGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEF
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB8 INPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRI
::::::::::: .: :.:::.::::::.::::::::::. .:: ::. ::::: .:. :
XP_006 INPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSI
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB8 KRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
..:.:.: ::::::::::::::::::::::::::::::::::::::::::::
XP_006 HHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
400 410 420 430 440
>>XP_005252764 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 1837 init1: 1228 opt: 1234 Z-score: 899.4 bits: 175.6 E(85289): 2.3e-43
Smith-Waterman score: 1835; 62.8% identity (78.9% similar) in 460 aa overlap (4-460:13-447)
10 20 30 40 50
pF1KB8 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTV-KEEGPEPWPGGPDPDVPGTD
: :... :: . : ..: . .::. : .: : : .
XP_005 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGV-GLE
10 20 30 40 50
60 70 80 90 100
pF1KB8 EASSACSTDWVIP--DPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCK
: . . : .: : .::::::::::::.::: ::::::::::::::::::::
XP_005 AAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 GFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKK
:::::::..:. .: :..:: : ::..::::::.::::::..:::::.::::::::: :
XP_005 GFFRRSVIKGA--HYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 KIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQ
:...:..:. .. : :..:: : : ::. : ::.
XP_005 KLKRQEEEQAHATSLP--PRASSP----PQILP----------------QLSPEQLGMIE
180 190 200 210
230 240 250 260 270 280
pF1KB8 QLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQV
.::::: :::.:::::. .:::::.. ::.::.::::::::::::::.:::::::::::.
XP_005 KLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQL
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB8 PGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEF
::::::.:::::::::.:.::.:::::.:::: .: :::::::.:...:: .:::::::
XP_005 PGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEF
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB8 INPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRI
::::::::::: .: :.:::.::::::.::::::::::. .:: ::. ::::: .:. :
XP_005 INPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSI
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB8 KRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
..:.:.: ::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
400 410 420 430 440
460 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:03:44 2016 done: Fri Nov 4 10:03:46 2016
Total Scan time: 9.650 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]