FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8151, 304 aa
  1>>>pF1KB8151 304 - 304 aa - 304 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2762+/-0.000325; mu= -0.3872+/- 0.020
 mean_var=305.0053+/-66.296, 0's: 0 Z-trim(123.8): 11  B-trim: 0 in 0/54
 Lambda= 0.073438
 statistics sampled from 44312 (44325) to 44312 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.52), width:  16
 Scan time:  8.340

The best scores are:                                      opt bits E(85289)
NP_058431 (OMIM: 164762) adapter molecule crk isof ( 304) 2088 233.9   3e-61
NP_005197 (OMIM: 164762) adapter molecule crk isof ( 204) 1378 158.5   1e-38
NP_005198 (OMIM: 602007) crk-like protein [Homo sa ( 303)  642 80.7   4e-15


>>NP_058431 (OMIM: 164762) adapter molecule crk isoform   (304 aa)
 initn: 2088 init1: 2088 opt: 2088  Z-score: 1220.5  bits: 233.9 E(85289): 3e-61
Smith-Waterman score: 2088; 100.0% identity (100.0% similar) in 304 aa overlap (1-304:1-304)

               10        20        30        40        50        60
pF1KB8 MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 IINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 MIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 MIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 RVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPD
              250       260       270       280       290       300

           
pF1KB8 EDFS
       ::::
NP_058 EDFS
           

>>NP_005197 (OMIM: 164762) adapter molecule crk isoform   (204 aa)
 initn: 1378 init1: 1378 opt: 1378  Z-score: 816.1  bits: 158.5 E(85289): 1e-38
Smith-Waterman score: 1378; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)

               10        20        30        40        50        60
pF1KB8 MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 MIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYA
       :::::::::::::::::::::::                                     
NP_005 MIPVPYVEKYRPASASVSALIGGR                                    
              190       200                                        

>>NP_005198 (OMIM: 602007) crk-like protein [Homo sapien  (303 aa)
 initn: 1223 init1: 403 opt: 642  Z-score: 392.6  bits: 80.7 E(85289): 4e-15
Smith-Waterman score: 1135; 57.5% identity (73.8% similar) in 320 aa overlap (5-302:6-302)

                10        20        30        40        50         
pF1KB8  MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSH
            ::: .::.:: : .::::: . :::::::.:::::::: ::::::::::::::::
NP_005 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 YIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVS
       :::::   :                 :..::::::: :::::::::::::::::::::. 
NP_005 YIINSLPNR-----------------RFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAP
                                70        80        90       100   

     120              130       140       150       160       170  
pF1KB8 R-------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNA
       :       : .. ..   ... ::::.:.:: ::: ::::::::.:: : .:::::::.:
NP_005 RYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA
           110       120       130       140       150       160   

            180       190       200       210        220       230 
pF1KB8 EDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPG-PYAQPSVNTPLP
       ....:. ::::::::::   .:        :.. . . .  : :::.  ::::...::::
NP_005 RNKDGRVGMIPVPYVEKLVRSSPH------GKHGNRNSNSYGIPEPAHAYAQPQTTTPLP
           170       180             190       200       210       

                           240       250       260       270       
pF1KB8 NL--------------QNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEG
        .              ::::..:..:::::: ::::::::::::..::::..:..:::::
NP_005 AVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEG
       220       230       240       250       260       270       

       280       290       300    
pF1KB8 ECNGKRGHFPFTHVRLLDQQNPDEDFS
       : ::..: ::::::...: :::::.  
NP_005 EVNGRKGLFPFTHVKIFDPQNPDENE 
       280       290       300    




304 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:54:04 2016 done: Fri Nov  4 19:54:05 2016
 Total Scan time:  8.340 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]