Result of FASTA (ccds) for
pF1KB8131
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8131, 183 aa
1>>>pF1KB8131 183 - 183 aa - 183 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8966+/-0.000889; mu= 15.3461+/- 0.054
mean_var=77.5014+/-15.498, 0's: 0 Z-trim(107.4): 198 B-trim: 311 in 1/51
Lambda= 0.145687
statistics sampled from 9340 (9561) to 9340 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.294), width: 16
Scan time: 1.400
The best scores are: opt bits E(32554)
CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 ( 183) 1195 260.2 5.1e-70
CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX ( 183) 1109 242.1 1.4e-64
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 1089 237.9 2.6e-63
CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 ( 184) 750 166.7 7.3e-42
CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 ( 184) 731 162.7 1.2e-40
CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX ( 117) 697 155.4 1.2e-38
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 584 131.8 2.4e-31
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 581 131.2 4.1e-31
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 581 131.3 4.3e-31
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 577 130.3 6.5e-31
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 571 129.1 1.6e-30
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 566 128.1 3.6e-30
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 560 126.8 7.8e-30
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 537 122.0 2.4e-28
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 534 121.3 3.2e-28
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 ( 204) 534 121.3 3.6e-28
CCDS6687.1 DIRAS2 gene_id:54769|Hs108|chr9 ( 199) 529 120.3 7.4e-28
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 527 119.9 1e-27
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19 ( 218) 526 119.7 1.2e-27
CCDS12092.1 DIRAS1 gene_id:148252|Hs108|chr19 ( 198) 516 117.5 4.9e-27
CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 ( 208) 510 116.3 1.2e-26
CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 ( 183) 488 111.6 2.7e-25
CCDS62431.1 RIT2 gene_id:6014|Hs108|chr18 ( 153) 460 105.7 1.4e-23
CCDS8673.1 RERG gene_id:85004|Hs108|chr12 ( 199) 439 101.3 3.7e-22
CCDS5927.1 RHEB gene_id:6009|Hs108|chr7 ( 184) 430 99.4 1.3e-21
CCDS53603.1 RRAS2 gene_id:22800|Hs108|chr11 ( 169) 427 98.8 1.9e-21
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 ( 183) 424 98.2 3.1e-21
CCDS58253.1 RAP1B gene_id:5908|Hs108|chr12 ( 165) 419 97.1 5.9e-21
CCDS58254.1 RAP1B gene_id:5908|Hs108|chr12 ( 142) 413 95.7 1.3e-20
CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 386 90.2 8.8e-19
CCDS82198.1 RAB37 gene_id:326624|Hs108|chr17 ( 196) 385 90.0 9.5e-19
CCDS32722.1 RAB37 gene_id:326624|Hs108|chr17 ( 223) 385 90.0 1e-18
CCDS54161.1 RAB37 gene_id:326624|Hs108|chr17 ( 228) 385 90.1 1.1e-18
CCDS641.1 DIRAS3 gene_id:9077|Hs108|chr1 ( 229) 374 87.7 5.3e-18
CCDS35246.1 ERAS gene_id:3266|Hs108|chrX ( 233) 372 87.3 7.1e-18
CCDS31613.1 RAB1B gene_id:81876|Hs108|chr11 ( 201) 362 85.2 2.8e-17
CCDS14156.1 RAB9A gene_id:9367|Hs108|chrX ( 201) 361 85.0 3.2e-17
CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 359 84.5 4.3e-17
CCDS10460.1 RAB26 gene_id:25837|Hs108|chr16 ( 256) 359 84.6 5.1e-17
CCDS13181.1 REM1 gene_id:28954|Hs108|chr20 ( 298) 358 84.5 6.5e-17
CCDS14766.1 RAB39B gene_id:116442|Hs108|chrX ( 213) 354 83.5 9.2e-17
CCDS10200.1 RASL12 gene_id:51285|Hs108|chr15 ( 266) 346 81.9 3.5e-16
CCDS9003.1 RAB21 gene_id:23011|Hs108|chr12 ( 225) 345 81.6 3.6e-16
CCDS76806.1 RAB26 gene_id:25837|Hs108|chr16 ( 190) 344 81.4 3.6e-16
CCDS6175.1 RAB2A gene_id:5862|Hs108|chr8 ( 212) 339 80.4 8.2e-16
CCDS6261.1 GEM gene_id:2669|Hs108|chr8 ( 296) 339 80.5 1e-15
CCDS12372.1 RAB3A gene_id:5864|Hs108|chr19 ( 220) 336 79.7 1.3e-15
CCDS42410.1 RAB12 gene_id:201475|Hs108|chr18 ( 244) 336 79.8 1.4e-15
CCDS14515.1 RAB9B gene_id:51209|Hs108|chrX ( 201) 334 79.3 1.6e-15
CCDS1058.1 RAB13 gene_id:5872|Hs108|chr1 ( 203) 334 79.3 1.6e-15
>>CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 (183 aa)
initn: 1195 init1: 1195 opt: 1195 Z-score: 1370.6 bits: 260.2 E(32554): 5.1e-70
Smith-Waterman score: 1195; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC
130 140 150 160 170 180
pF1KB8 NIQ
:::
CCDS94 NIQ
>>CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX (183 aa)
initn: 1126 init1: 1109 opt: 1109 Z-score: 1272.9 bits: 242.1 E(32554): 1.4e-64
Smith-Waterman score: 1109; 91.3% identity (97.3% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
::::::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::
CCDS14 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC
: :::: ::::::::.::::::::::::::.:::::::::::::::.. :.:.: ::..:
CCDS14 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC
130 140 150 160 170 180
pF1KB8 NIQ
.:
CCDS14 VVQ
>>CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 (183 aa)
initn: 1106 init1: 1089 opt: 1089 Z-score: 1250.2 bits: 237.9 E(32554): 2.6e-63
Smith-Waterman score: 1089; 91.2% identity (97.3% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS31 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
:::::::::::::::::::::::::::::::::::::::::::::::.::.:::::::::
CCDS31 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC
:.::::: .::.::::::.:::::::::.:. ::::::::::::::::::. :. :::::
CCDS31 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC
130 140 150 160 170 180
pF1KB8 NIQ
:
CCDS31 VIL
>>CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 (184 aa)
initn: 699 init1: 636 opt: 750 Z-score: 865.0 bits: 166.7 E(32554): 7.3e-42
Smith-Waterman score: 750; 62.4% identity (84.0% similar) in 181 aa overlap (1-180:1-181)
10 20 30 40 50 60
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..::: . .::::::::
CCDS84 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: : ::.:::::: ::
CCDS84 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 ESEREVSSSEGRALAEEW-GCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSA
:.:: :.. .:. ::..: .: :.:.::::: :.:.: ..:::.: . .: : ..
CCDS84 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
130 140 150 160 170 180
180
pF1KB8 CNIQ
:
CCDS84 CLLL
>>CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 (184 aa)
initn: 697 init1: 634 opt: 731 Z-score: 843.5 bits: 162.7 E(32554): 1.2e-40
Smith-Waterman score: 731; 61.4% identity (83.7% similar) in 184 aa overlap (1-182:1-183)
10 20 30 40 50 60
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..:::.. .::::::::
CCDS89 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: . ::.:::::: ::
CCDS89 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 ESEREVSSSEGRALAEEWG-CPFMETSAKSKTMVDELFAEIVRQMNYAAQ-PDKDDPCCS
:.:: :.. .:. ::..:. : :.:.::::: :.:.: ..:::.: . : : :
CCDS89 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKK-S
130 140 150 160 170
180
pF1KB8 ACNIQ
.:..
CCDS89 SCQLL
180
>>CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX (117 aa)
initn: 732 init1: 697 opt: 697 Z-score: 807.4 bits: 155.4 E(32554): 1.2e-38
Smith-Waterman score: 697; 86.3% identity (95.7% similar) in 117 aa overlap (67-183:1-117)
40 50 60 70 80 90
pF1KB8 EDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPM
::::::::::::::::::::::::::::::
CCDS76 MRDLYIKNGQGFILVYSLVNQQSFQDIKPM
10 20 30
100 110 120 130 140 150
pF1KB8 RDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDEL
::::.:::::::::.:::::::::: :::: ::::::::.::::::::::::::.:::::
CCDS76 RDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDEL
40 50 60 70 80 90
160 170 180
pF1KB8 FAEIVRQMNYAAQPDKDDPCCSACNIQ
::::::::::.. :.:.: ::..: .:
CCDS76 FAEIVRQMNYSSLPEKQDQCCTTCVVQ
100 110
>>CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 (189 aa)
initn: 579 init1: 466 opt: 584 Z-score: 676.3 bits: 131.8 E(32554): 2.4e-31
Smith-Waterman score: 584; 46.5% identity (75.7% similar) in 185 aa overlap (1-180:1-184)
10 20 30 40 50 60
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS76 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
:....::: :...:.::. :... : .::.::. .:.:: ::: . ::..::::: ::
CCDS76 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAA-----QPDKDDP
. : : : ... ::. .: :..:::::.. :.. : .::.. ::.. :
CCDS76 -AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGP
130 140 150 160 170
180
pF1KB8 CCSACNIQ
: .:
CCDS76 GCMSCKCVLS
180
>>CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 (219 aa)
initn: 604 init1: 581 opt: 581 Z-score: 672.1 bits: 131.2 E(32554): 4.1e-31
Smith-Waterman score: 581; 49.7% identity (83.4% similar) in 163 aa overlap (2-164:20-182)
10 20 30 40
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRK
::::.:.::.:::::::.:.::.. : : .:::::: :.
CCDS11 MDSGTRPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 EIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIR
.:..:. :. :.:::::: .:..::: :.. :.:::. ::.....::.... ... : :
CCDS11 RIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 VKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVR
:.: . .::.::::: ::.. :.:.. :: :::.:..:::.:::: . ..:..: .::
CCDS11 VRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVR
130 140 150 160 170 180
170 180
pF1KB8 QMNYAAQPDKDDPCCSACNIQ
..
CCDS11 EIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT
190 200 210
>>CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 (236 aa)
initn: 604 init1: 581 opt: 581 Z-score: 671.7 bits: 131.3 E(32554): 4.3e-31
Smith-Waterman score: 581; 49.7% identity (83.4% similar) in 163 aa overlap (2-164:37-199)
10 20 30
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEK
::::.:.::.:::::::.:.::.. : :
CCDS58 LGATEEGPKRTMDSGTRPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPED
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 YDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQ
.:::::: :. .:..:. :. :.:::::: .:..::: :.. :.:::. ::.....::.
CCDS58 HDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 DIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAKSKT
... ... : ::.: . .::.::::: ::.. :.:.. :: :::.:..:::.:::: .
CCDS58 EVREFKQLIYRVRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRY
130 140 150 160 170 180
160 170 180
pF1KB8 MVDELFAEIVRQMNYAAQPDKDDPCCSACNIQ
..:..: .::..
CCDS58 YIDDVFHALVREIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT
190 200 210 220 230
>>CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 (188 aa)
initn: 560 init1: 473 opt: 577 Z-score: 668.4 bits: 130.3 E(32554): 6.5e-31
Smith-Waterman score: 577; 49.4% identity (80.5% similar) in 174 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB8 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
:....::: :...:.::. :... : .::.::. .:.:: ::: : ::..::::: ::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM-NYAAQPDKDDPCCSA
: : :...... ::. .: ::.:::::.. ::. : .::.. .. . .::
CCDS87 PS-RTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKK
130 140 150 160 170
180
pF1KB8 CNIQ
CCDS87 KSKTKCVIM
180
183 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:49:46 2016 done: Fri Nov 4 09:49:46 2016
Total Scan time: 1.400 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]