Result of FASTA (omim) for
pF1KB8106
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8106, 177 aa
1>>>pF1KB8106 177 - 177 aa - 177 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0434+/-0.000396; mu= 8.0019+/- 0.024
mean_var=56.6243+/-11.230, 0's: 0 Z-trim(110.8): 31 B-trim: 0 in 0/55
Lambda= 0.170440
statistics sampled from 19144 (19173) to 19144 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.225), width: 16
Scan time: 3.950
The best scores are: opt bits E(85289)
NP_057141 (OMIM: 615472) coatomer subunit zeta-1 i ( 177) 1113 281.9 3.6e-76
NP_001258665 (OMIM: 615472) coatomer subunit zeta- ( 185) 1081 274.1 8.8e-74
XP_016874486 (OMIM: 615472) PREDICTED: coatomer su ( 180) 937 238.7 3.9e-63
NP_001258663 (OMIM: 615472) coatomer subunit zeta- ( 154) 935 238.2 4.7e-63
NP_001258664 (OMIM: 615472) coatomer subunit zeta- ( 160) 920 234.5 6.2e-62
NP_057513 (OMIM: 615526) coatomer subunit zeta-2 [ ( 210) 859 219.5 2.7e-57
XP_011523176 (OMIM: 615526) PREDICTED: coatomer su ( 184) 508 133.2 2.3e-31
NP_005820 (OMIM: 602416) AP-3 complex subunit sigm ( 193) 166 49.1 4.9e-06
XP_016864513 (OMIM: 601507) PREDICTED: AP-3 comple ( 262) 165 48.8 8e-06
XP_011541438 (OMIM: 601507) PREDICTED: AP-3 comple ( 262) 165 48.8 8e-06
NP_001034658 (OMIM: 615781,616106) AP-1 complex su ( 154) 160 47.6 1.1e-05
NP_001305022 (OMIM: 601507) AP-3 complex subunit s ( 162) 159 47.4 1.4e-05
NP_001275 (OMIM: 601507) AP-3 complex subunit sigm ( 193) 154 46.1 3.8e-05
NP_001259000 (OMIM: 300629) AP-1 complex subunit s ( 160) 123 38.5 0.0062
XP_011543901 (OMIM: 300629) PREDICTED: AP-1 comple ( 202) 123 38.5 0.0078
XP_016885414 (OMIM: 300629) PREDICTED: AP-1 comple ( 202) 123 38.5 0.0078
NP_003907 (OMIM: 300629) AP-1 complex subunit sigm ( 157) 121 38.0 0.0085
>>NP_057141 (OMIM: 615472) coatomer subunit zeta-1 isofo (177 aa)
initn: 1113 init1: 1113 opt: 1113 Z-score: 1488.5 bits: 281.9 E(85289): 3.6e-76
Smith-Waterman score: 1113; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)
10 20 30 40 50 60
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
130 140 150 160 170
>>NP_001258665 (OMIM: 615472) coatomer subunit zeta-1 is (185 aa)
initn: 1080 init1: 1080 opt: 1081 Z-score: 1445.6 bits: 274.1 E(85289): 8.8e-74
Smith-Waterman score: 1081; 97.2% identity (98.3% similar) in 177 aa overlap (1-177:9-185)
10 20 30 40 50
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKT
: . . ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGFRTEGMFVSLQEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 HRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 ALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIK
130 140 150 160 170 180
pF1KB8 WSLLR
:::::
NP_001 WSLLR
>>XP_016874486 (OMIM: 615472) PREDICTED: coatomer subuni (180 aa)
initn: 937 init1: 937 opt: 937 Z-score: 1254.5 bits: 238.7 E(85289): 3.9e-63
Smith-Waterman score: 937; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
:::::::::::::::::::::::::::::
XP_016 LFLAVDEIVDGGVILESDPQQVVHRVALRVSKNVFLCIPASIHKHPPEPDLLDVSSSWGS
130 140 150 160 170 180
>>NP_001258663 (OMIM: 615472) coatomer subunit zeta-1 is (154 aa)
initn: 954 init1: 935 opt: 935 Z-score: 1253.1 bits: 238.2 E(85289): 4.7e-63
Smith-Waterman score: 935; 100.0% identity (100.0% similar) in 148 aa overlap (30-177:7-154)
10 20 30 40 50 60
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
:::::::::::::::::::::::::::::::
NP_001 MEALILYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
10 20 30
70 80 90 100 110 120
pF1KB8 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
40 50 60 70 80 90
130 140 150 160 170
pF1KB8 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
100 110 120 130 140 150
>>NP_001258664 (OMIM: 615472) coatomer subunit zeta-1 is (160 aa)
initn: 920 init1: 920 opt: 920 Z-score: 1232.8 bits: 234.5 E(85289): 6.2e-62
Smith-Waterman score: 965; 90.4% identity (90.4% similar) in 177 aa overlap (1-177:1-160)
10 20 30 40 50 60
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
:::::::::::::::::::::::::: ::::::::::::::
NP_001 LFLAVDEIVDGGVILESDPQQVVHRV-----------------LQSAKEQIKWSLLR
130 140 150 160
>>NP_057513 (OMIM: 615526) coatomer subunit zeta-2 [Homo (210 aa)
initn: 873 init1: 859 opt: 859 Z-score: 1149.6 bits: 219.5 E(85289): 2.7e-57
Smith-Waterman score: 859; 74.9% identity (94.7% similar) in 171 aa overlap (7-177:40-210)
10 20 30
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYP
::::::.::..:::::: ::.:::::::.:
NP_057 PHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 SVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNC
:.::: .::::.:::: ::.::::.. :.:.:::.::::..::.:::::::::::.::.:
NP_057 SMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 LFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLT
::.::..::::::::: :::::.: ::..:::::::::::::::::...: .:..: ::
NP_057 LFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLT
130 140 150 160 170 180
160 170
pF1KB8 EQTVSQVLQSAKEQIKWSLLR
::.:.:::::::::::::::.
NP_057 EQSVAQVLQSAKEQIKWSLLK
190 200 210
>>XP_011523176 (OMIM: 615526) PREDICTED: coatomer subuni (184 aa)
initn: 718 init1: 503 opt: 508 Z-score: 684.2 bits: 133.2 E(85289): 2.3e-31
Smith-Waterman score: 656; 62.0% identity (80.7% similar) in 171 aa overlap (7-177:40-184)
10 20 30
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYP
::::::.::..:::::: ::.:::::::.:
XP_011 PHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 SVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNC
:.::: .::::.:::: ::.::::.. :.:.:::.::::..::.:::::::::::.::.:
XP_011 SMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 LFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLT
::.::..:: .::::::::::...: .:..: ::
XP_011 LFESLNHML--------------------------SVILESDPQQVIQKVNFRADDGGLT
130 140 150 160
160 170
pF1KB8 EQTVSQVLQSAKEQIKWSLLR
::.:.:::::::::::::::.
XP_011 EQSVAQVLQSAKEQIKWSLLK
170 180
>>NP_005820 (OMIM: 602416) AP-3 complex subunit sigma-2 (193 aa)
initn: 107 init1: 74 opt: 166 Z-score: 229.3 bits: 49.1 E(85289): 4.9e-06
Smith-Waterman score: 166; 23.2% identity (62.0% similar) in 142 aa overlap (13-146:2-141)
10 20 30 40 50 60
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
..:::...: : ....:. .: .:. .... .: :.
NP_005 MIQAILVFNNHGKPRLVRFYQ-RFPEEIQQQIVRETFHLVLKRDDNICN
10 20 30 40
70 80 90 100 110
pF1KB8 LLEGLTVV--------YKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKR
.::: ... :. ::: .: :.:: .. ... . ..:.. . .:: .
NP_005 FLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCF-ENVCEL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 ALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIK
:. .:. . ..:.: ::..::.. ...: ..
NP_005 DLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKN
110 120 130 140 150 160
pF1KB8 WSLLR
NP_005 INLPEIPRNINIGDLNIKVPNLSQFV
170 180 190
>>XP_016864513 (OMIM: 601507) PREDICTED: AP-3 complex su (262 aa)
initn: 151 init1: 71 opt: 165 Z-score: 225.6 bits: 48.8 E(85289): 8e-06
Smith-Waterman score: 165; 22.9% identity (60.6% similar) in 170 aa overlap (8-169:97-260)
10 20 30
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS
:. .:::::..: : ..:.:. :
XP_016 GGGWGRIAGEITRRGSRARPRPGPQCPPGRPGTAMIKAILIFNNHGKPRLSKFYQP-YSE
70 80 90 100 110 120
40 50 60 70 80
pF1KB8 VKEQKAFEKNIFNKTHRTDSEIALLEG-LTV-------VYKSSIDLYFYVIGSSYENELM
.:. ..... ..: .. .::: : . .:. ::: .: :.::
XP_016 DTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELG
130 140 150 160 170 180
90 100 110 120 130 140
pF1KB8 LMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALR
.. ... . ..:.. . .:: . :. ... . . :.: ::..::.. ...: .. .
XP_016 ILDLIQVFVETLDKCF-ENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQ
190 200 210 220 230 240
150 160 170
pF1KB8 GEDVPLTEQTVSQVLQSAKEQIKWSLLR
.. :.. . ..:: ..
XP_016 NK----LEKSETFIFQSPRQDR
250 260
>>XP_011541438 (OMIM: 601507) PREDICTED: AP-3 complex su (262 aa)
initn: 151 init1: 71 opt: 165 Z-score: 225.6 bits: 48.8 E(85289): 8e-06
Smith-Waterman score: 165; 22.9% identity (60.6% similar) in 170 aa overlap (8-169:97-260)
10 20 30
pF1KB8 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPS
:. .:::::..: : ..:.:. :
XP_011 GGGWGRIAGEITRRGSRARPRPGPQCPPGRPGTAMIKAILIFNNHGKPRLSKFYQP-YSE
70 80 90 100 110 120
40 50 60 70 80
pF1KB8 VKEQKAFEKNIFNKTHRTDSEIALLEG-LTV-------VYKSSIDLYFYVIGSSYENELM
.:. ..... ..: .. .::: : . .:. ::: .: :.::
XP_011 DTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELG
130 140 150 160 170 180
90 100 110 120 130 140
pF1KB8 LMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALR
.. ... . ..:.. . .:: . :. ... . . :.: ::..::.. ...: .. .
XP_011 ILDLIQVFVETLDKCF-ENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQ
190 200 210 220 230 240
150 160 170
pF1KB8 GEDVPLTEQTVSQVLQSAKEQIKWSLLR
.. :.. . ..:: ..
XP_011 NK----LEKSETFIFQSPRQDR
250 260
177 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:32:35 2016 done: Fri Nov 4 09:32:35 2016
Total Scan time: 3.950 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]