Result of FASTA (omim) for
pF1KB7893
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7893, 588 aa
1>>>pF1KB7893 588 - 588 aa - 588 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8722+/-0.000386; mu= 7.4851+/- 0.024
mean_var=166.3922+/-32.370, 0's: 0 Z-trim(117.8): 187 B-trim: 42 in 1/53
Lambda= 0.099428
statistics sampled from 29967 (30181) to 29967 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.354), width: 16
Scan time: 9.460
The best scores are: opt bits E(85289)
NP_036233 (OMIM: 610658) tripartite motif-containi ( 588) 3944 578.2 2.6e-164
XP_011541034 (OMIM: 610658) PREDICTED: tripartite ( 621) 3628 532.9 1.2e-150
XP_011541031 (OMIM: 610658) PREDICTED: tripartite ( 622) 3621 531.9 2.4e-150
NP_001317311 (OMIM: 610658) tripartite motif-conta ( 327) 2136 318.7 1.9e-86
XP_005271547 (OMIM: 610658) PREDICTED: tripartite ( 321) 2130 317.8 3.5e-86
XP_016872942 (OMIM: 610658) PREDICTED: tripartite ( 361) 1813 272.4 1.8e-72
XP_011541035 (OMIM: 610658) PREDICTED: tripartite ( 355) 1807 271.5 3.3e-72
NP_006461 (OMIM: 609505) tripartite motif-containi ( 564) 502 84.5 1.1e-15
NP_005073 (OMIM: 600453) E3 ubiquitin/ISG15 ligase ( 630) 422 73.0 3.3e-12
NP_258411 (OMIM: 611041) tripartite motif-containi ( 638) 405 70.6 1.8e-11
NP_477514 (OMIM: 607564) tripartite motif-containi ( 488) 275 51.8 6.1e-06
NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516) 275 51.9 6.3e-06
NP_001180208 (OMIM: 189960,300000,300552) E3 ubiqu ( 489) 266 50.6 1.5e-05
XP_016885031 (OMIM: 189960,300000,300552) PREDICTE ( 489) 266 50.6 1.5e-05
XP_016884728 (OMIM: 300204,300928) PREDICTED: prob ( 685) 268 50.9 1.6e-05
NP_438112 (OMIM: 300204,300928) probable E3 ubiqui ( 705) 268 51.0 1.6e-05
XP_016885029 (OMIM: 189960,300000,300552) PREDICTE ( 552) 266 50.6 1.6e-05
XP_005262119 (OMIM: 300204,300928) PREDICTED: prob ( 715) 268 51.0 1.6e-05
NP_036348 (OMIM: 300204,300928) probable E3 ubiqui ( 735) 268 51.0 1.7e-05
NP_150632 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 266 50.7 1.9e-05
NP_001092094 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 266 50.7 1.9e-05
NP_000372 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 266 50.7 1.9e-05
NP_001180206 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 266 50.7 1.9e-05
XP_016885025 (OMIM: 189960,300000,300552) PREDICTE ( 667) 266 50.7 1.9e-05
XP_016873949 (OMIM: 608487) PREDICTED: tripartite ( 314) 254 48.7 3.5e-05
XP_011518729 (OMIM: 608487) PREDICTED: tripartite ( 271) 249 47.9 5.1e-05
NP_001180207 (OMIM: 189960,300000,300552) E3 ubiqu ( 540) 254 48.9 5.3e-05
XP_016885030 (OMIM: 189960,300000,300552) PREDICTE ( 540) 254 48.9 5.3e-05
NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 253 48.7 5.5e-05
NP_569074 (OMIM: 605684) tripartite motif-containi ( 270) 248 47.8 5.6e-05
NP_001186502 (OMIM: 606559) E3 ubiquitin-protein l ( 494) 252 48.5 6e-05
XP_016873951 (OMIM: 608487) PREDICTED: tripartite ( 300) 248 47.8 6.1e-05
XP_006718421 (OMIM: 608487) PREDICTED: tripartite ( 265) 247 47.6 6.1e-05
XP_016873952 (OMIM: 608487) PREDICTED: tripartite ( 265) 247 47.6 6.1e-05
NP_149084 (OMIM: 608487) tripartite motif-containi ( 326) 248 47.8 6.5e-05
XP_005253241 (OMIM: 608487) PREDICTED: tripartite ( 326) 248 47.8 6.5e-05
XP_011543827 (OMIM: 189960,300000,300552) PREDICTE ( 718) 254 49.0 6.6e-05
XP_011543829 (OMIM: 189960,300000,300552) PREDICTE ( 718) 254 49.0 6.6e-05
XP_006724555 (OMIM: 189960,300000,300552) PREDICTE ( 718) 254 49.0 6.6e-05
XP_005274593 (OMIM: 189960,300000,300552) PREDICTE ( 718) 254 49.0 6.6e-05
XP_011543828 (OMIM: 189960,300000,300552) PREDICTE ( 718) 254 49.0 6.6e-05
XP_016885023 (OMIM: 189960,300000,300552) PREDICTE ( 718) 254 49.0 6.6e-05
XP_005274594 (OMIM: 189960,300000,300552) PREDICTE ( 718) 254 49.0 6.6e-05
NP_149083 (OMIM: 608487) tripartite motif-containi ( 347) 248 47.9 6.8e-05
XP_011518728 (OMIM: 608487) PREDICTED: tripartite ( 310) 247 47.7 6.9e-05
XP_016873950 (OMIM: 608487) PREDICTED: tripartite ( 310) 247 47.7 6.9e-05
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 249 48.1 7.9e-05
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 248 48.0 8.9e-05
NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 248 48.0 8.9e-05
NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 248 48.0 8.9e-05
>>NP_036233 (OMIM: 610658) tripartite motif-containing p (588 aa)
initn: 3944 init1: 3944 opt: 3944 Z-score: 3070.9 bits: 578.2 E(85289): 2.6e-164
Smith-Waterman score: 3944; 100.0% identity (100.0% similar) in 588 aa overlap (1-588:1-588)
10 20 30 40 50 60
pF1KB7 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS
490 500 510 520 530 540
550 560 570 580
pF1KB7 LKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP
::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP
550 560 570 580
>>XP_011541034 (OMIM: 610658) PREDICTED: tripartite moti (621 aa)
initn: 3628 init1: 3628 opt: 3628 Z-score: 2825.6 bits: 532.9 E(85289): 1.2e-150
Smith-Waterman score: 3868; 94.7% identity (94.7% similar) in 621 aa overlap (1-588:1-621)
10 20 30 40 50 60
pF1KB7 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS
490 500 510 520 530 540
550 560
pF1KB7 LKG---------------------------------YPSLMRSQSPKAQPQTWKSGKQTM
::: ::::::::::::::::::::::::
XP_011 LKGTGKTPYQFTTLGQATAEFSKPLGRSGLSKNNPGYPSLMRSQSPKAQPQTWKSGKQTM
550 560 570 580 590 600
570 580
pF1KB7 LSHYRPFYVNKGNGIGSNEAP
:::::::::::::::::::::
XP_011 LSHYRPFYVNKGNGIGSNEAP
610 620
>>XP_011541031 (OMIM: 610658) PREDICTED: tripartite moti (622 aa)
initn: 3930 init1: 3620 opt: 3621 Z-score: 2820.2 bits: 531.9 E(85289): 2.4e-150
Smith-Waterman score: 3851; 94.5% identity (94.5% similar) in 620 aa overlap (1-586:1-620)
10 20 30 40 50 60
pF1KB7 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS
490 500 510 520 530 540
550 560
pF1KB7 LK----------------------------------GYPSLMRSQSPKAQPQTWKSGKQT
:: ::::::::::::::::::::::::
XP_011 LKAGTGKTPYQFTTLGQATAEFSKPLGRSGLSKNNPGYPSLMRSQSPKAQPQTWKSGKQT
550 560 570 580 590 600
570 580
pF1KB7 MLSHYRPFYVNKGNGIGSNEAP
::::::::::::::::::::
XP_011 MLSHYRPFYVNKGNGIGSNEAP
610 620
>>NP_001317311 (OMIM: 610658) tripartite motif-containin (327 aa)
initn: 2136 init1: 2136 opt: 2136 Z-score: 1672.9 bits: 318.7 E(85289): 1.9e-86
Smith-Waterman score: 2136; 100.0% identity (100.0% similar) in 321 aa overlap (268-588:7-327)
240 250 260 270 280 290
pF1KB7 TDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKD
::::::::::::::::::::::::::::::
NP_001 MVPGISETELSLQKEQLQLKIIEIEDEAEKWQKEKD
10 20 30
300 310 320 330 340 350
pF1KB7 RIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVL
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB7 HEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLL
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB7 NVCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTP
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB7 KGGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSS
220 230 240 250 260 270
540 550 560 570 580
pF1KB7 SFSLKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFSLKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP
280 290 300 310 320
>>XP_005271547 (OMIM: 610658) PREDICTED: tripartite moti (321 aa)
initn: 2130 init1: 2130 opt: 2130 Z-score: 1668.3 bits: 317.8 E(85289): 3.5e-86
Smith-Waterman score: 2130; 100.0% identity (100.0% similar) in 320 aa overlap (269-588:2-321)
240 250 260 270 280 290
pF1KB7 DQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDR
::::::::::::::::::::::::::::::
XP_005 MTELSLQKEQLQLKIIEIEDEAEKWQKEKDR
10 20 30
300 310 320 330 340 350
pF1KB7 IKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLH
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB7 EDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLN
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB7 VCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPK
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB7 GGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSS
220 230 240 250 260 270
540 550 560 570 580
pF1KB7 FSLKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSLKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP
280 290 300 310 320
>>XP_016872942 (OMIM: 610658) PREDICTED: tripartite moti (361 aa)
initn: 2122 init1: 1812 opt: 1813 Z-score: 1421.9 bits: 272.4 E(85289): 1.8e-72
Smith-Waterman score: 2043; 90.4% identity (90.4% similar) in 353 aa overlap (268-586:7-359)
240 250 260 270 280 290
pF1KB7 TDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKD
::::::::::::::::::::::::::::::
XP_016 MVPGISETELSLQKEQLQLKIIEIEDEAEKWQKEKD
10 20 30
300 310 320 330 340 350
pF1KB7 RIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVL
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB7 HEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLL
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB7 NVCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTP
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB7 KGGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSS
220 230 240 250 260 270
540 550 560
pF1KB7 SFSLK----------------------------------GYPSLMRSQSPKAQPQTWKSG
::::: :::::::::::::::::::::
XP_016 SFSLKAGTGKTPYQFTTLGQATAEFSKPLGRSGLSKNNPGYPSLMRSQSPKAQPQTWKSG
280 290 300 310 320 330
570 580
pF1KB7 KQTMLSHYRPFYVNKGNGIGSNEAP
:::::::::::::::::::::::
XP_016 KQTMLSHYRPFYVNKGNGIGSNEAP
340 350 360
>>XP_011541035 (OMIM: 610658) PREDICTED: tripartite moti (355 aa)
initn: 2116 init1: 1806 opt: 1807 Z-score: 1417.3 bits: 271.5 E(85289): 3.3e-72
Smith-Waterman score: 2037; 90.3% identity (90.3% similar) in 352 aa overlap (269-586:2-353)
240 250 260 270 280 290
pF1KB7 DQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDR
::::::::::::::::::::::::::::::
XP_011 MTELSLQKEQLQLKIIEIEDEAEKWQKEKDR
10 20 30
300 310 320 330 340 350
pF1KB7 IKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLH
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB7 EDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLN
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB7 VCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPK
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB7 GGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSS
220 230 240 250 260 270
540 550 560
pF1KB7 FSLK----------------------------------GYPSLMRSQSPKAQPQTWKSGK
:::: ::::::::::::::::::::::
XP_011 FSLKAGTGKTPYQFTTLGQATAEFSKPLGRSGLSKNNPGYPSLMRSQSPKAQPQTWKSGK
280 290 300 310 320 330
570 580
pF1KB7 QTMLSHYRPFYVNKGNGIGSNEAP
::::::::::::::::::::::
XP_011 QTMLSHYRPFYVNKGNGIGSNEAP
340 350
>>NP_006461 (OMIM: 609505) tripartite motif-containing p (564 aa)
initn: 520 init1: 247 opt: 502 Z-score: 402.8 bits: 84.5 E(85289): 1.1e-15
Smith-Waterman score: 502; 33.3% identity (66.7% similar) in 240 aa overlap (169-406:73-309)
140 150 160 170 180 190
pF1KB7 TVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNKQ--KAVKSCLVCQASFCE
.::::: :. . . :::::::.:....::
NP_006 EDVGSSEKLGRETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCE
50 60 70 80 90 100
200 210 220 230 240 250
pF1KB7 LHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKNHS
::.:: . ...: : ::..: . : ::.: . . :: :: ::: : :::..:.
NP_006 EHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCC-QEHSGHT
110 120 130 140 150 160
260 270 280 290 300 310
pF1KB7 TVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNFRD
:... :. .::.::. . .:. :. :. . : .. . ... ::. :..: .
NP_006 IVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGE
170 180 190 200 210 220
320 330 340 350 360 370
pF1KB7 LVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISDSVLF
:. ..: . .: ::..:: :..:.. : :. :. ....:: :.. .::..: :
NP_006 LLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQF
230 240 250 260 270 280
380 390 400 410 420 430
pF1KB7 LQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKADLSRNF
:.:. . .. .. .:. .: :. . :
NP_006 LEEYCKFKNTEDI--TFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEE
290 300 310 320 330
>>NP_005073 (OMIM: 600453) E3 ubiquitin/ISG15 ligase TRI (630 aa)
initn: 296 init1: 296 opt: 422 Z-score: 340.1 bits: 73.0 E(85289): 3.3e-12
Smith-Waterman score: 422; 28.8% identity (62.9% similar) in 267 aa overlap (166-426:100-357)
140 150 160 170 180 190
pF1KB7 RKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNKQKAVKSCLVCQASFC
: . .: :: :. :. :::.::::.::::
NP_005 CNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCL--KEAAVKTCLVCMASFC
70 80 90 100 110 120
200 210 220 230 240 250
pF1KB7 ELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKNH
. ::.::... ::.:: : :.::. ::: :.. :.:: . :::..:. :::.
NP_005 QEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV-EHKTC
130 140 150 160 170 180
260 270 280 290 300 310
pF1KB7 STVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKS--FTTNEKA-ILEQ
: ... .:.:. :. : ...: . .:. .. . ..: .. .:.:.:. :.:
NP_005 SPASLSQASADLEATL---RHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQ
190 200 210 220 230 240
320 330 340 350 360 370
pF1KB7 NFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISD
.. .. :. .. ....:. . .. .:.. : .. . .. :. :: . :
NP_005 EYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRD
250 260 270 280 290 300
380 390 400 410 420
pF1KB7 SVLFLQEFGALMSNYSLP---PPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCK
::.. . : . . : : . : :.. :. :: ..:..: . :. ....
NP_005 EFEFLEKASKLRGISTKPVYIPEVELNHKLIK--GIHQSTIDLKNEL-KQCIGRLQEPTP
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB7 ADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGGVRTSYQPSS
NP_005 SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL
370 380 390 400 410 420
>>NP_258411 (OMIM: 611041) tripartite motif-containing p (638 aa)
initn: 355 init1: 294 opt: 405 Z-score: 326.9 bits: 70.6 E(85289): 1.8e-11
Smith-Waterman score: 405; 28.9% identity (56.4% similar) in 266 aa overlap (166-427:122-384)
140 150 160 170 180 190
pF1KB7 RKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCI-GNKQKAVKSCLVCQASF
.: : : ::.: : :. ::: : :::
NP_258 APALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASF
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 CELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKN
: :: :: .. :.: :.:. :.: .: :: : . .: .:.....:.: : :::..
NP_258 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLRPLERYCRAERVCLCEACAAQEHRG
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB7 HSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNF
: : .:. .: .:.: : .. .. :. . .. ::: .. :. . . :
NP_258 HELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLF
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB7 RDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISDSV
: . :. . .: . .:. : . . . . .:. . : . .:. :. .:::
NP_258 ADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSV
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB7 LFLQEFGAL---MSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKAD
::::. :: . . : : : .. . . :.. .: : .:. . :..
NP_258 SFLQELLALRLALEDGCGPGPGPPRELSFTKSS--QAVRAVRDMLAVACVNQWEQLRGPG
340 350 360 370 380
440 450 460 470 480 490
pF1KB7 LSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGGVRTSYQPSSPG
NP_258 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
390 400 410 420 430 440
588 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:18:37 2016 done: Fri Nov 4 21:18:38 2016
Total Scan time: 9.460 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]