Result of FASTA (omim) for
pF1KB7851
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7851, 548 aa
1>>>pF1KB7851 548 - 548 aa - 548 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.3118+/-0.000364; mu= -11.7705+/- 0.023
mean_var=469.7762+/-96.490, 0's: 0 Z-trim(126.2): 148 B-trim: 0 in 0/59
Lambda= 0.059174
statistics sampled from 51312 (51486) to 51312 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.604), width: 16
Scan time: 13.770
The best scores are: opt bits E(85289)
NP_006485 (OMIM: 600775,611888) ETS domain-contain ( 548) 3864 344.0 7.1e-94
NP_001295331 (OMIM: 600775,611888) ETS domain-cont ( 473) 3320 297.5 6.1e-80
NP_001287964 (OMIM: 600775,611888) ETS domain-cont ( 473) 3320 297.5 6.1e-80
XP_016881957 (OMIM: 600775,611888) PREDICTED: ETS ( 473) 3320 297.5 6.1e-80
XP_016881958 (OMIM: 600775,611888) PREDICTED: ETS ( 473) 3320 297.5 6.1e-80
NP_001299585 (OMIM: 600775,611888) ETS domain-cont ( 473) 3320 297.5 6.1e-80
NP_001138784 (OMIM: 164873) ETS translocation vari ( 512) 962 96.2 2.6e-19
XP_006711273 (OMIM: 164873) PREDICTED: ETS translo ( 512) 962 96.2 2.6e-19
NP_005231 (OMIM: 164873) ETS translocation variant ( 143) 718 74.9 1.9e-13
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 449 52.1 2.2e-06
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 410 48.8 2.4e-05
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 410 49.0 3.2e-05
XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 410 49.0 3.4e-05
NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 410 49.0 3.4e-05
XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 410 49.0 3.4e-05
XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 410 49.0 3.4e-05
XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 410 49.0 3.4e-05
NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 410 49.1 3.6e-05
NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 407 48.7 3.7e-05
NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 407 48.7 3.8e-05
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 407 48.8 4.1e-05
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 407 48.8 4.2e-05
NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 407 48.8 4.3e-05
XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 407 48.8 4.3e-05
NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 407 48.8 4.4e-05
NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 407 48.8 4.5e-05
NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 407 48.8 4.5e-05
NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 407 48.8 4.5e-05
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 387 47.0 0.00012
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 387 47.0 0.00013
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 387 47.1 0.00014
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 377 46.0 0.00015
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 377 46.2 0.00024
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 377 46.2 0.00025
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 377 46.2 0.00025
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 377 46.3 0.00026
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 377 46.3 0.00027
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 377 46.3 0.00027
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 377 46.3 0.00028
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 374 46.0 0.00031
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 374 46.0 0.00031
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 374 46.0 0.00031
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 374 46.1 0.00038
NP_068567 (OMIM: 600246) ETS domain-containing pro ( 405) 364 45.1 0.00051
XP_016856069 (OMIM: 600246) PREDICTED: ETS domain- ( 413) 364 45.1 0.00051
NP_001964 (OMIM: 600246) ETS domain-containing pro ( 431) 364 45.1 0.00053
XP_005245007 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 364 45.1 0.00053
XP_005245008 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 364 45.1 0.00053
NP_001291478 (OMIM: 609358) ETS translocation vari ( 155) 347 43.3 0.00069
XP_011527822 (OMIM: 600609) PREDICTED: GA-binding ( 454) 358 44.6 0.00078
>>NP_006485 (OMIM: 600775,611888) ETS domain-containing (548 aa)
initn: 3864 init1: 3864 opt: 3864 Z-score: 1806.3 bits: 344.0 E(85289): 7.1e-94
Smith-Waterman score: 3864; 100.0% identity (100.0% similar) in 548 aa overlap (1-548:1-548)
10 20 30 40 50 60
pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 DEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFID
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPGVFRVYPRPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPGVFRVYPRPRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 SHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGLAEGAGALAPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGLAEGAGALAPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 PPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGASQCMPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGASQCMPL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 KLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQ
490 500 510 520 530 540
pF1KB7 LSLEHRDS
::::::::
NP_006 LSLEHRDS
>>NP_001295331 (OMIM: 600775,611888) ETS domain-containi (473 aa)
initn: 3320 init1: 3320 opt: 3320 Z-score: 1556.1 bits: 297.5 E(85289): 6.1e-80
Smith-Waterman score: 3320; 100.0% identity (100.0% similar) in 473 aa overlap (76-548:1-473)
50 60 70 80 90 100
pF1KB7 IAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
NP_001 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
110 120 130 140 150 160
pF1KB7 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB7 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB7 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
400 410 420 430 440 450
530 540
pF1KB7 TPRRVSSDLQHATAQLSLEHRDS
:::::::::::::::::::::::
NP_001 TPRRVSSDLQHATAQLSLEHRDS
460 470
>>NP_001287964 (OMIM: 600775,611888) ETS domain-containi (473 aa)
initn: 3320 init1: 3320 opt: 3320 Z-score: 1556.1 bits: 297.5 E(85289): 6.1e-80
Smith-Waterman score: 3320; 100.0% identity (100.0% similar) in 473 aa overlap (76-548:1-473)
50 60 70 80 90 100
pF1KB7 IAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
NP_001 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
110 120 130 140 150 160
pF1KB7 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB7 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB7 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
400 410 420 430 440 450
530 540
pF1KB7 TPRRVSSDLQHATAQLSLEHRDS
:::::::::::::::::::::::
NP_001 TPRRVSSDLQHATAQLSLEHRDS
460 470
>>XP_016881957 (OMIM: 600775,611888) PREDICTED: ETS doma (473 aa)
initn: 3320 init1: 3320 opt: 3320 Z-score: 1556.1 bits: 297.5 E(85289): 6.1e-80
Smith-Waterman score: 3320; 100.0% identity (100.0% similar) in 473 aa overlap (76-548:1-473)
50 60 70 80 90 100
pF1KB7 IAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
XP_016 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
110 120 130 140 150 160
pF1KB7 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB7 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB7 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
400 410 420 430 440 450
530 540
pF1KB7 TPRRVSSDLQHATAQLSLEHRDS
:::::::::::::::::::::::
XP_016 TPRRVSSDLQHATAQLSLEHRDS
460 470
>>XP_016881958 (OMIM: 600775,611888) PREDICTED: ETS doma (473 aa)
initn: 3320 init1: 3320 opt: 3320 Z-score: 1556.1 bits: 297.5 E(85289): 6.1e-80
Smith-Waterman score: 3320; 100.0% identity (100.0% similar) in 473 aa overlap (76-548:1-473)
50 60 70 80 90 100
pF1KB7 IAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
XP_016 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
110 120 130 140 150 160
pF1KB7 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB7 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB7 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
400 410 420 430 440 450
530 540
pF1KB7 TPRRVSSDLQHATAQLSLEHRDS
:::::::::::::::::::::::
XP_016 TPRRVSSDLQHATAQLSLEHRDS
460 470
>>NP_001299585 (OMIM: 600775,611888) ETS domain-containi (473 aa)
initn: 3320 init1: 3320 opt: 3320 Z-score: 1556.1 bits: 297.5 E(85289): 6.1e-80
Smith-Waterman score: 3320; 100.0% identity (100.0% similar) in 473 aa overlap (76-548:1-473)
50 60 70 80 90 100
pF1KB7 IAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
NP_001 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
110 120 130 140 150 160
pF1KB7 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB7 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB7 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL
400 410 420 430 440 450
530 540
pF1KB7 TPRRVSSDLQHATAQLSLEHRDS
:::::::::::::::::::::::
NP_001 TPRRVSSDLQHATAQLSLEHRDS
460 470
>>NP_001138784 (OMIM: 164873) ETS translocation variant (512 aa)
initn: 1060 init1: 480 opt: 962 Z-score: 467.8 bits: 96.2 E(85289): 2.6e-19
Smith-Waterman score: 1324; 45.6% identity (63.0% similar) in 551 aa overlap (2-502:10-504)
10 20 30 40 50
pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQ-GD
: . :. ::::::: :::::::::::::::::::.:::.. ::::: :.
NP_001 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 YGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_001 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 VLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSS
:. :::::.. ..:.:::::::::...:.:.::: .. :::.: . : :.::
NP_001 VMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPP---LDTHSPTNDVQ-PGRFSASS--
130 140 150 160 170
180 190 200 210 220 230
pF1KB7 LFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGP-PDLGAFRGPPLARLPHDPG
..: .. .: . ::::. . : : : : . .:. : ... . :
NP_001 ----LTASGQESSNGTDRKTELSELEDGSAADWR-RGVDPVSSRNAIGGGGIGHQKRKPD
180 190 200 210 220
240 250 260 270 280
pF1KB7 V-FRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPS
. . .. :: :.: ::: :::. : :..: .:::: .::: ..:.::: :::. :
NP_001 IMLPLFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSS
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 GGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCP
: :::.::.::.::.... ::.:::::::.: .::::.:: : .:
NP_001 -----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP----PLQC-
290 300 310 320 330
350 360 370 380 390 400
pF1KB7 LPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGL
: :: :. :..::::::.::..: :.. .: . . ...
NP_001 --QMHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPVTTPTMASI
340 350 360 370
410 420 430 440 450
pF1KB7 AEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------EEDGEVFK
::.::::: :: . : . : . ..:. :: : .:
NP_001 ------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKGTIFA
380 390 400 410 420
460 470 480 490
pF1KB7 TPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRFKRRWSEDC
: ::: : .: .::. :.: . :: :::.::::..:
NP_001 RPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRWNDDP
430 440 450 460 470 480
500 510 520 530 540
pF1KB7 R----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQLS
. : .:.:: :
NP_001 EARELSKSGKFLWNGSGPQGLATAAADA
490 500 510
>>XP_006711273 (OMIM: 164873) PREDICTED: ETS translocati (512 aa)
initn: 1060 init1: 480 opt: 962 Z-score: 467.8 bits: 96.2 E(85289): 2.6e-19
Smith-Waterman score: 1324; 45.6% identity (63.0% similar) in 551 aa overlap (2-502:10-504)
10 20 30 40 50
pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQ-GD
: . :. ::::::: :::::::::::::::::::.:::.. ::::: :.
XP_006 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 YGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_006 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 VLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSS
:. :::::.. ..:.:::::::::...:.:.::: .. :::.: . : :.::
XP_006 VMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPP---LDTHSPTNDVQ-PGRFSASS--
130 140 150 160 170
180 190 200 210 220 230
pF1KB7 LFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGP-PDLGAFRGPPLARLPHDPG
..: .. .: . ::::. . : : : : . .:. : ... . :
XP_006 ----LTASGQESSNGTDRKTELSELEDGSAADWR-RGVDPVSSRNAIGGGGIGHQKRKPD
180 190 200 210 220
240 250 260 270 280
pF1KB7 V-FRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPS
. . .. :: :.: ::: :::. : :..: .:::: .::: ..:.::: :::. :
XP_006 IMLPLFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSS
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 GGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCP
: :::.::.::.::.... ::.:::::::.: .::::.:: : .:
XP_006 -----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP----PLQC-
290 300 310 320 330
350 360 370 380 390 400
pF1KB7 LPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGL
: :: :. :..::::::.::..: :.. .: . . ...
XP_006 --QMHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPVTTPTMASI
340 350 360 370
410 420 430 440 450
pF1KB7 AEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------EEDGEVFK
::.::::: :: . : . : . ..:. :: : .:
XP_006 ------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKGTIFA
380 390 400 410 420
460 470 480 490
pF1KB7 TPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRFKRRWSEDC
: ::: : .: .::. :.: . :: :::.::::..:
XP_006 RPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRWNDDP
430 440 450 460 470 480
500 510 520 530 540
pF1KB7 R----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQLS
. : .:.:: :
XP_006 EARELSKSGKFLWNGSGPQGLATAAADA
490 500 510
>>NP_005231 (OMIM: 164873) ETS translocation variant 3 i (143 aa)
initn: 719 init1: 475 opt: 718 Z-score: 362.4 bits: 74.9 E(85289): 1.9e-13
Smith-Waterman score: 718; 82.4% identity (90.4% similar) in 125 aa overlap (2-125:10-134)
10 20 30 40 50
pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQ-GD
: . :. ::::::: :::::::::::::::::::.:::.. ::::: :.
NP_005 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 YGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_005 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 VLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSS
:. :::::.. .:
NP_005 VMPNYPFINIRSSGKIQTLLVGN
130 140
>>NP_059991 (OMIM: 607150) protein FEV [Homo sapiens] (238 aa)
initn: 459 init1: 402 opt: 449 Z-score: 235.4 bits: 52.1 E(85289): 2.2e-06
Smith-Waterman score: 449; 39.6% identity (63.4% similar) in 202 aa overlap (12-211:31-223)
10 20 30 40
pF1KB7 MKTPADTGFAFPDWA-YKPESSPGSRQIQLWHFILELLRKE
:.:. .: . :: :::::.:.:::: .
NP_059 MRQSGASQPLLINMYLPDPVGDGLFKDGKNPSWGPLSPAVQKGSGQIQLWQFLLELLADR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 EYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGK
: :::.: .::: . ::::::: :: :: ::.::::::::::::::.: :. :..::
NP_059 ANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMSKVHGK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 RFTYKFNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPR
:..:.:.:. :. . : . ..:. .: . . :. ...: . :.: :
NP_059 RYAYRFDFQGLAQACQP-PPAHAHAAAAAAAAAAAAQDGALYKLPAG-----LAPLPFPG
130 140 150 160 170
170 180 190 200 210
pF1KB7 -SPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRG
: ..:... : . : : .. . .:. : . .: ::::
NP_059 LSKLNLMAASAGVAPAGFSYWPGPGPAATAAAATAALYPSPSLQP---PPGPFGAVAAAS
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 PPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTP
NP_059 HLGGHYH
548 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:38:24 2016 done: Fri Nov 4 22:38:27 2016
Total Scan time: 13.770 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]