Result of FASTA (omim) for
pF1KB7779
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7779, 434 aa
1>>>pF1KB7779 434 - 434 aa - 434 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9544+/-0.000324; mu= 22.4536+/- 0.021
mean_var=128.8771+/-25.858, 0's: 0 Z-trim(119.5): 170 B-trim: 0 in 0/56
Lambda= 0.112976
statistics sampled from 33316 (33529) to 33316 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.393), width: 16
Scan time: 10.000
The best scores are: opt bits E(85289)
NP_006186 (OMIM: 176312) pre-B-cell leukemia trans ( 434) 2866 478.3 1.7e-134
NP_002576 (OMIM: 176310) pre-B-cell leukemia trans ( 430) 2361 396.0 1e-109
XP_005245286 (OMIM: 176310) PREDICTED: pre-B-cell ( 430) 2361 396.0 1e-109
NP_001128250 (OMIM: 176312) pre-B-cell leukemia tr ( 359) 2345 393.2 5.6e-109
NP_001317711 (OMIM: 176312) pre-B-cell leukemia tr ( 351) 2211 371.4 2.1e-102
XP_016856884 (OMIM: 176310) PREDICTED: pre-B-cell ( 406) 2156 362.5 1.1e-99
NP_001191892 (OMIM: 176310) pre-B-cell leukemia tr ( 420) 2156 362.5 1.2e-99
XP_005245285 (OMIM: 176310) PREDICTED: pre-B-cell ( 486) 1976 333.3 8.5e-91
XP_006717193 (OMIM: 176312) PREDICTED: pre-B-cell ( 455) 1862 314.7 3.2e-85
XP_006717194 (OMIM: 176312) PREDICTED: pre-B-cell ( 372) 1852 312.9 8.9e-85
NP_002577 (OMIM: 176311) pre-B-cell leukemia trans ( 430) 1836 310.4 5.9e-84
XP_016856885 (OMIM: 176310) PREDICTED: pre-B-cell ( 347) 1815 306.8 5.6e-83
NP_001191890 (OMIM: 176310) pre-B-cell leukemia tr ( 347) 1815 306.8 5.6e-83
XP_011507892 (OMIM: 176310) PREDICTED: pre-B-cell ( 462) 1771 299.8 9.4e-81
XP_016870275 (OMIM: 176312) PREDICTED: pre-B-cell ( 276) 1690 286.3 6.7e-77
NP_079521 (OMIM: 608127) pre-B-cell leukemia trans ( 374) 1589 270.0 7.1e-72
XP_011507894 (OMIM: 176310) PREDICTED: pre-B-cell ( 403) 1430 244.2 4.7e-64
XP_011507893 (OMIM: 176310) PREDICTED: pre-B-cell ( 403) 1430 244.2 4.7e-64
XP_011517057 (OMIM: 176312) PREDICTED: pre-B-cell ( 380) 1341 229.6 1.1e-59
XP_016882816 (OMIM: 608127) PREDICTED: pre-B-cell ( 343) 1294 221.9 2e-57
XP_016882815 (OMIM: 608127) PREDICTED: pre-B-cell ( 357) 1294 221.9 2.1e-57
XP_011526622 (OMIM: 608127) PREDICTED: pre-B-cell ( 391) 1294 222.0 2.2e-57
XP_016882817 (OMIM: 608127) PREDICTED: pre-B-cell ( 327) 1203 207.0 5.7e-53
XP_006722974 (OMIM: 608127) PREDICTED: pre-B-cell ( 288) 1172 201.9 1.8e-51
XP_011526624 (OMIM: 608127) PREDICTED: pre-B-cell ( 288) 1172 201.9 1.8e-51
XP_006717196 (OMIM: 176312) PREDICTED: pre-B-cell ( 274) 1027 178.2 2.2e-44
XP_016882818 (OMIM: 608127) PREDICTED: pre-B-cell ( 209) 812 143.0 6.8e-34
XP_016882819 (OMIM: 608127) PREDICTED: pre-B-cell ( 188) 306 60.5 4.3e-09
XP_016859632 (OMIM: 601739) PREDICTED: homeobox pr ( 352) 213 45.7 0.00022
XP_006718957 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 212 45.5 0.00025
XP_016873600 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 212 45.5 0.00025
XP_011541249 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 212 45.5 0.00025
XP_016859631 (OMIM: 601739) PREDICTED: homeobox pr ( 417) 213 45.8 0.00025
XP_016859630 (OMIM: 601739) PREDICTED: homeobox pr ( 433) 213 45.9 0.00025
XP_005271700 (OMIM: 613066) PREDICTED: homeobox pr ( 443) 212 45.7 0.00029
XP_011541247 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 212 45.7 0.0003
XP_016873599 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 212 45.7 0.0003
XP_005271699 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 212 45.7 0.0003
XP_011541246 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 212 45.7 0.0003
NP_071345 (OMIM: 613066) homeobox protein PKNOX2 [ ( 472) 212 45.7 0.0003
XP_016877694 (OMIM: 601740) PREDICTED: homeobox pr ( 306) 194 42.5 0.0018
NP_758527 (OMIM: 601740) homeobox protein Meis2 is ( 306) 194 42.5 0.0018
NP_002390 (OMIM: 601740) homeobox protein Meis2 is ( 381) 194 42.7 0.002
NP_001207411 (OMIM: 601740) homeobox protein Meis2 ( 470) 195 43.0 0.002
NP_733776 (OMIM: 601740) homeobox protein Meis2 is ( 470) 195 43.0 0.002
XP_006720588 (OMIM: 601740) PREDICTED: homeobox pr ( 393) 194 42.7 0.002
NP_733774 (OMIM: 601740) homeobox protein Meis2 is ( 394) 194 42.7 0.002
XP_006720592 (OMIM: 601740) PREDICTED: homeobox pr ( 255) 190 41.8 0.0025
XP_011519893 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 191 42.1 0.0026
XP_006720590 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 191 42.1 0.0026
>>NP_006186 (OMIM: 176312) pre-B-cell leukemia transcrip (434 aa)
initn: 2866 init1: 2866 opt: 2866 Z-score: 2535.6 bits: 478.3 E(85289): 1.7e-134
Smith-Waterman score: 2866; 100.0% identity (100.0% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 QEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTS
370 380 390 400 410 420
430
pF1KB7 PTEGPGSVHSDTSN
::::::::::::::
NP_006 PTEGPGSVHSDTSN
430
>>NP_002576 (OMIM: 176310) pre-B-cell leukemia transcrip (430 aa)
initn: 1266 init1: 1200 opt: 2361 Z-score: 2090.8 bits: 396.0 E(85289): 1e-109
Smith-Waterman score: 2361; 83.2% identity (93.9% similar) in 440 aa overlap (1-434:1-430)
10 20 30 40 50
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGD----GRKQDIGDILHQIMTI
::.: :.... :::..::: :.. : ..:: : ::::::::::.:::::
NP_002 MDEQPRLMHSHAGVGMAGHP---GLS----QHLQDGAGGTEGEGGRKQDIGDILQQIMTI
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 TDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLL
::::::::::.::::::::::::::.::::::::: :::::::::.: ::::::::::::
NP_002 TDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 AEGVSGPEKGGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACN
::::.::::::::::::::::::::. ::::.:::::::::.::::::::::::::::::
NP_002 AEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_002 EFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 RRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK
:::::::.::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_002 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 NIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNM
::::::::::.:::::::::... : ...:.:::.:::: :::.:::. ::::.::..
NP_002 NIGKFQEEANIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 QSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATT
::::::::::.:::::::::::::::::.:::::::::.....:::....::::::::::
NP_002 QSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATT
360 370 380 390 400 410
420 430
pF1KB7 PSSVTSPTEGPGSVHSDTSN
::::::::::::::::::::
NP_002 PSSVTSPTEGPGSVHSDTSN
420 430
>>XP_005245286 (OMIM: 176310) PREDICTED: pre-B-cell leuk (430 aa)
initn: 1266 init1: 1200 opt: 2361 Z-score: 2090.8 bits: 396.0 E(85289): 1e-109
Smith-Waterman score: 2361; 83.2% identity (93.9% similar) in 440 aa overlap (1-434:1-430)
10 20 30 40 50
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGD----GRKQDIGDILHQIMTI
::.: :.... :::..::: :.. : ..:: : ::::::::::.:::::
XP_005 MDEQPRLMHSHAGVGMAGHP---GLS----QHLQDGAGGTEGEGGRKQDIGDILQQIMTI
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 TDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLL
::::::::::.::::::::::::::.::::::::: :::::::::.: ::::::::::::
XP_005 TDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 AEGVSGPEKGGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACN
::::.::::::::::::::::::::. ::::.:::::::::.::::::::::::::::::
XP_005 AEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_005 EFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 RRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK
:::::::.::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_005 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 NIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNM
::::::::::.:::::::::... : ...:.:::.:::: :::.:::. ::::.::..
XP_005 NIGKFQEEANIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 QSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATT
::::::::::.:::::::::::::::::.:::::::::.....:::....::::::::::
XP_005 QSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATT
360 370 380 390 400 410
420 430
pF1KB7 PSSVTSPTEGPGSVHSDTSN
::::::::::::::::::::
XP_005 PSSVTSPTEGPGSVHSDTSN
420 430
>>NP_001128250 (OMIM: 176312) pre-B-cell leukemia transc (359 aa)
initn: 2345 init1: 2345 opt: 2345 Z-score: 2077.5 bits: 393.2 E(85289): 5.6e-109
Smith-Waterman score: 2345; 100.0% identity (100.0% similar) in 359 aa overlap (76-434:1-359)
50 60 70 80 90 100
pF1KB7 IGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPD
::::::::::::::::::::::::::::::
NP_001 MKPALFSVLCEIKEKTGLSIRGAQEEDPPD
10 20 30
110 120 130 140 150 160
pF1KB7 PQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 ELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 MILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNW
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 FGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 NSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNA
280 290 300 310 320 330
410 420 430
pF1KB7 NGGWQDATTPSSVTSPTEGPGSVHSDTSN
:::::::::::::::::::::::::::::
NP_001 NGGWQDATTPSSVTSPTEGPGSVHSDTSN
340 350
>>NP_001317711 (OMIM: 176312) pre-B-cell leukemia transc (351 aa)
initn: 2211 init1: 2211 opt: 2211 Z-score: 1959.5 bits: 371.4 E(85289): 2.1e-102
Smith-Waterman score: 2211; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 QEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGD
:::::::::::::::::::::::::::::::::::::
NP_001 QEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGGYPPSCYQSDGRLQ
310 320 330 340 350
370 380 390 400 410 420
pF1KB7 SYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTS
>>XP_016856884 (OMIM: 176310) PREDICTED: pre-B-cell leuk (406 aa)
initn: 1609 init1: 1200 opt: 2156 Z-score: 1910.4 bits: 362.5 E(85289): 1.1e-99
Smith-Waterman score: 2156; 82.0% identity (93.4% similar) in 410 aa overlap (1-404:1-400)
10 20 30 40 50
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGD----GRKQDIGDILHQIMTI
::.: :.... :::..::: :.. : ..:: : ::::::::::.:::::
XP_016 MDEQPRLMHSHAGVGMAGHP---GLS----QHLQDGAGGTEGEGGRKQDIGDILQQIMTI
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 TDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLL
::::::::::.::::::::::::::.::::::::: :::::::::.: ::::::::::::
XP_016 TDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 AEGVSGPEKGGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACN
::::.::::::::::::::::::::. ::::.:::::::::.::::::::::::::::::
XP_016 AEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_016 EFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 RRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK
:::::::.::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_016 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 NIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNM
::::::::::.:::::::::... : ...:.:::.:::: :::.:::. ::::.::..
XP_016 NIGKFQEEANIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 QSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATT
::::::::::.:::::::::::::::::.:::::::::.....:::....
XP_016 QSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISEIARTY
360 370 380 390 400
420 430
pF1KB7 PSSVTSPTEGPGSVHSDTSN
>>NP_001191892 (OMIM: 176310) pre-B-cell leukemia transc (420 aa)
initn: 1609 init1: 1200 opt: 2156 Z-score: 1910.3 bits: 362.5 E(85289): 1.2e-99
Smith-Waterman score: 2156; 82.0% identity (93.4% similar) in 410 aa overlap (1-404:1-400)
10 20 30 40 50
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGD----GRKQDIGDILHQIMTI
::.: :.... :::..::: :.. : ..:: : ::::::::::.:::::
NP_001 MDEQPRLMHSHAGVGMAGHP---GLS----QHLQDGAGGTEGEGGRKQDIGDILQQIMTI
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 TDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLL
::::::::::.::::::::::::::.::::::::: :::::::::.: ::::::::::::
NP_001 TDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 AEGVSGPEKGGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACN
::::.::::::::::::::::::::. ::::.:::::::::.::::::::::::::::::
NP_001 AEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 EFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 RRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK
:::::::.::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_001 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 NIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNM
::::::::::.:::::::::... : ...:.:::.:::: :::.:::. ::::.::..
NP_001 NIGKFQEEANIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 QSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATT
::::::::::.:::::::::::::::::.:::::::::.....:::....
NP_001 QSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISHLPRHPRQAH
360 370 380 390 400 410
420 430
pF1KB7 PSSVTSPTEGPGSVHSDTSN
NP_001 YHFRLPTWHP
420
>>XP_005245285 (OMIM: 176310) PREDICTED: pre-B-cell leuk (486 aa)
initn: 1577 init1: 1200 opt: 1976 Z-score: 1751.1 bits: 333.3 E(85289): 8.5e-91
Smith-Waterman score: 2186; 77.0% identity (85.5% similar) in 461 aa overlap (33-434:29-486)
10 20 30 40 50 60
pF1KB7 DQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDG-RKQDIGDILHQIMTITDQSL
: :..:.: :::::::::.::::::::::
XP_005 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSL
10 20 30 40 50
70 80 90
pF1KB7 DEAQAKKHALNCHRMKPALFSVLCEIKEKT------------------------------
:::::.::::::::::::::.:::::::::
XP_005 DEAQARKHALNCHRMKPALFNVLCEIKEKTELKEARSRNCPSLFFLVTRIQSSVRHRVLS
60 70 80 90 100 110
100 110 120
pF1KB7 -----G---------------------LSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEK
: :::::::::.: ::::::::::::::::.::::
XP_005 SASTSGNPVTPQPTHHHPSFGWGEGKVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEK
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 GGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNL
::::::::::::::::. ::::.:::::::::.:::::::::::::::::::::::::::
XP_005 GGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNL
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 LREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSK
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::.:
XP_005 LREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNK
240 250 260 270 280 290
250 260 270 280 290 300
pF1KB7 QATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEA
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_005 QATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEA
300 310 320 330 340 350
310 320 330 340 350 360
pF1KB7 NLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNMQSLNGDSYQ
:.:::::::::... : ...:.:::.:::: :::.:::. ::::.::..:::::::::
XP_005 NIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQ
360 370 380 390 400 410
370 380 390 400 410 420
pF1KB7 GSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTE
:.:::::::::::::::::.:::::::::.....:::....:::::::::::::::::::
XP_005 GAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTE
420 430 440 450 460 470
430
pF1KB7 GPGSVHSDTSN
:::::::::::
XP_005 GPGSVHSDTSN
480
>>XP_006717193 (OMIM: 176312) PREDICTED: pre-B-cell leuk (455 aa)
initn: 1852 init1: 1852 opt: 1862 Z-score: 1651.0 bits: 314.7 E(85289): 3.2e-85
Smith-Waterman score: 2814; 95.4% identity (95.4% similar) in 455 aa overlap (1-434:1-455)
10 20 30 40 50 60
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
190 200 210 220 230 240
250 260 270 280
pF1KB7 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_006 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQSLVKDPKERGSKGSDIQPT
250 260 270 280 290 300
290 300 310 320 330
pF1KB7 --VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSS
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB7 GSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYS
370 380 390 400 410 420
400 410 420 430
pF1KB7 PHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN
:::::::::::::::::::::::::::::::::::
XP_006 PHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN
430 440 450
>>XP_006717194 (OMIM: 176312) PREDICTED: pre-B-cell leuk (372 aa)
initn: 1852 init1: 1852 opt: 1852 Z-score: 1643.0 bits: 312.9 E(85289): 8.9e-85
Smith-Waterman score: 2159; 94.1% identity (94.1% similar) in 358 aa overlap (1-337:1-358)
10 20 30 40 50 60
pF1KB7 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRR
190 200 210 220 230 240
250 260 270 280
pF1KB7 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_006 NFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQSLVKDPKERGSKGSDIQPT
250 260 270 280 290 300
290 300 310 320 330
pF1KB7 --VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGGY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB7 GSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYS
XP_006 PPSCYQSDGRLQ
370
434 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:17:09 2016 done: Fri Nov 4 22:17:11 2016
Total Scan time: 10.000 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]