Result of FASTA (omim) for
pF1KB7755
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7755, 446 aa
1>>>pF1KB7755 446 - 446 aa - 446 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0835+/-0.00033; mu= 2.1678+/- 0.021
mean_var=280.8083+/-58.044, 0's: 0 Z-trim(124.4): 150 B-trim: 45 in 1/59
Lambda= 0.076537
statistics sampled from 45812 (45986) to 45812 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.539), width: 16
Scan time: 9.980
The best scores are: opt bits E(85289)
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 3155 361.3 2.9e-99
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 1178 143.1 1.6e-33
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 869 108.9 2.8e-23
NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 482 66.2 1.9e-10
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 448 62.4 2.5e-09
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474) 442 61.8 4.5e-09
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 435 60.9 6.6e-09
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 433 60.6 6.8e-09
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 428 60.0 9e-09
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 413 58.3 2.5e-08
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 413 58.6 4e-08
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 404 57.3 5.1e-08
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 408 58.0 5.3e-08
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315) 400 57.0 8.4e-08
NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 400 57.1 1.1e-07
NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 327 49.0 2.5e-05
NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 331 49.7 2.7e-05
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 327 49.0 2.7e-05
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 327 49.3 4e-05
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 327 49.3 4e-05
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 327 49.3 4e-05
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 327 49.3 4e-05
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 327 49.3 4e-05
NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 327 49.3 4e-05
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 327 49.3 4e-05
NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 327 49.3 4.1e-05
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 327 49.3 4.1e-05
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 327 49.3 4.1e-05
NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 327 49.3 4.1e-05
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 327 49.3 4.1e-05
NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 327 49.3 4.2e-05
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 327 49.3 4.2e-05
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 327 49.3 4.3e-05
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 327 49.3 4.3e-05
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 312 47.1 5.2e-05
NP_001139283 (OMIM: 607257) transcription factor S ( 801) 317 48.2 9.2e-05
NP_059978 (OMIM: 607257) transcription factor SOX- ( 804) 317 48.2 9.3e-05
NP_201583 (OMIM: 607257) transcription factor SOX- ( 808) 317 48.2 9.3e-05
NP_001139291 (OMIM: 607257) transcription factor S ( 841) 317 48.2 9.6e-05
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 314 47.8 9.7e-05
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 314 47.8 9.8e-05
NP_001295094 (OMIM: 606698) transcription factor S ( 448) 270 42.8 0.0023
>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H (446 aa)
initn: 3155 init1: 3155 opt: 3155 Z-score: 1903.2 bits: 361.3 E(85289): 2.9e-99
Smith-Waterman score: 3155; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)
10 20 30 40 50 60
pF1KB7 MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 DERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 QAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 CSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRPYASPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRPYASPLL
370 380 390 400 410 420
430 440
pF1KB7 NGLALPPAHSPTSHWDQPVYTTLTRP
::::::::::::::::::::::::::
NP_055 NGLALPPAHSPTSHWDQPVYTTLTRP
430 440
>>NP_000337 (OMIM: 114290,608160,616425) transcription f (509 aa)
initn: 1081 init1: 586 opt: 1178 Z-score: 722.7 bits: 143.1 E(85289): 1.6e-33
Smith-Waterman score: 1243; 48.5% identity (67.0% similar) in 470 aa overlap (16-419:19-480)
10 20 30 40 50
pF1KB7 MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDP-
:: : : . ::: .. :: .::. . .:.:
NP_000 MNLLDPFMKMTDEQEKGLSG-APSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPD
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 --AEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQ
:. ...::.:::.:::::::::::.::::::: .:.. : ::::::::::::::::
NP_000 LKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSS--KNKPHVKRPMNAFMVWAQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 AARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPR
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_000 AARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPR
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 RRKSAKAGHSDSDSGAELGPHPGGGAVYKA--------EAGLGDGHHHGDHTGQTHGPPT
::::.: :..... ..: : . .:..:: .:... : :.:.::..::::
NP_000 RRKSVKNGQAEAEEATEQ-THISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 PPTTPKTELQQAGAKPELKLEGRRPVDSGRQN-IDFSNVDISELSSEVMGTMDAFDVHEF
:::::::..: . : .:: ::: ..::: ::: .:::.::::.:......:::.::
NP_000 PPTTPKTDVQPG--KADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEF
240 250 260 270 280 290
290 300 310 320
pF1KB7 DQYLPLGG-PA-PPEPGQA-YGGAY-------FHAGASPVWAHKS-APSA------SASP
::::: .: :. : ::. : :.: :.:. :: :. :: .: :
NP_000 DQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPP
300 310 320 330 340 350
330 340 350
pF1KB7 TETGPPRP---------------------------------HIKTEQPSPGHYGDQPRGS
. .::.: :::::: ::.::..: . :
NP_000 APQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHS
360 370 380 390 400 410
360 370 380 390 400 410
pF1KB7 PDYGSCS--GQSSATPAAPAGPFAGSQGDYGDLQ-ASSYYGAYPGYAPGLYQYPCFHSP-
:. . : . .:. : :.. :: :: : : .::::. : . :::. . .:
NP_000 PQQIAYSPFNLPHYSPSYP--PITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPA
420 430 440 450 460 470
420 430 440
pF1KB7 RRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
.::. .:.
NP_000 QRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
480 490 500
>>NP_008872 (OMIM: 602229,609136,611584,613266) transcri (466 aa)
initn: 1010 init1: 579 opt: 869 Z-score: 538.8 bits: 108.9 E(85289): 2.8e-23
Smith-Waterman score: 1281; 50.3% identity (68.4% similar) in 475 aa overlap (2-446:10-466)
10 20 30 40 50
pF1KB7 MLDMSEARSQPP-CSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGG
...: . :. : : :.: :.. :. . . : : : :. : :
NP_008 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLG--PDGGGGGSGLRA-SPGPGELG-KVKK
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ARGDPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMV
. : .:: :..::.:::.::::::.::::.::::::: .: : :.:::::::::::::
NP_008 EQQD-GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNG--ASKSKPHVKRPMNAFMV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 WAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKY
::::::::::::::::::::::::::::::::.::.::::.:::::::.:::::::::::
NP_008 WAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKY
120 130 140 150 160 170
180 190 200 210
pF1KB7 QPRRRKSAKA--GHSDSDSG-AELGPHPGGGAVYKA------EAGLGDGHHHGD--H-TG
::::::..:: :... .: :: : . : ::. . : :. :. : .:
NP_008 QPRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSG
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 QTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDA
:.:::::::::::::::.. : : : .:: ..:. .:::.::::.:.: :::..:..
NP_008 QSHGPPTPPTTPKTELQSGKADP--KRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMET
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB7 FDVHEFDQYLPLGG-PAP----PEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPP
::: :.::::: .: :. : . :.: :.. .: : : . : :: ..::
NP_008 FDVAELDQYLPPNGHPGHVSSYSAAGYGLGSALAVASGHSAWISK--PPGVALPT-VSPP
300 310 320 330 340
340 350 360 370 380
pF1KB7 ----RPHIKTEQ--PS-PGHYGDQPRGSP-DYGSCS--GQSSATPAAPAGPFAGSQGDYG
. ..::: :. : :: ::: : : : : .:: :. : ::.
NP_008 GVDAKAQVKTETAGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQF-----DYS
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB7 DLQASSYYGAYPGYAPGLYQYPCFHSP-RRPYASPLLN-GLALPPAHSPTSHWDQPVYTT
: : :. : .. : : :::. . .: .:: . . . . . : .:::: ::.::::::
NP_008 DHQPSGPYYGHSGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPT-HWEQPVYTT
410 420 430 440 450 460
pF1KB7 LTRP
:.::
NP_008 LSRP
>>NP_071899 (OMIM: 610928,613674) transcription factor S (414 aa)
initn: 496 init1: 424 opt: 482 Z-score: 308.5 bits: 66.2 E(85289): 1.9e-10
Smith-Waterman score: 509; 34.6% identity (54.4% similar) in 364 aa overlap (55-373:5-352)
30 40 50 60 70 80
pF1KB7 VEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAADERFPACIRDAVSQVLKGYD---W
: . :.:.. . ..:. :. : :
NP_071 MSSPDAGYASDDQ--SQTQSALPAVMAGLGPCPW
10 20 30
90 100 110 120
pF1KB7 --SLVP---MPVRG----------GGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPH
:: : : :.: :..: :.. ...::::::::::. :..::.: :
NP_071 AESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 LHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK------
:::::::: ::: :. :. .:::::::::::::::: .:::.:::.:::::..:
NP_071 LHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVE
100 110 120 130 140 150
190 200 210 220 230
pF1KB7 AG--HSDSD-SGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPT-PPTTPK--TE
.: :. .. ..: :::. :: : : ::: . . : ::: :: .
NP_071 GGFLHGLAEPQAAALGPE--GGRV--AMDGLG---LQFPEQGFPAGPPLLPPHMGGHYRD
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 LQQAGAKPELKLEGRRPVDSGRQN-IDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGG
:. :: : :.: :. . . .: . : . ... . : : .. . : .:
NP_071 CQSLGAPP---LDGY-PLPTPDTSPLDGVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAG
210 220 230 240 250 260
300 310 320 330
pF1KB7 PAPPEPGQAY-------GGAYFHAGASPVWAHKSAPSASASPTETG-------PPRPHIK
: : : . .: . . .: : . .: .:: : : . : .
NP_071 PPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQH
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB7 TEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYA
.: : : :: :. : .... :. ::
NP_071 QHQHHPPGPG-QPSPPPEALPC--RDGTDPSQPAELLGEVDRTEFEQYLHFVCKPEMGLP
330 340 350 360 370
400 410 420 430 440
pF1KB7 PGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
NP_071 YQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
380 390 400 410
>>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H (391 aa)
initn: 466 init1: 410 opt: 448 Z-score: 288.5 bits: 62.4 E(85289): 2.5e-09
Smith-Waterman score: 478; 32.9% identity (54.0% similar) in 350 aa overlap (90-428:39-357)
60 70 80 90 100 110
pF1KB7 ADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRK
:::::: . .:::::::::::... :::
NP_005 DLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRK
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB7 LADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KS
.:.. :..::.:.:: :: :...::.:::::..::.:::. : :.::::::.:::. :.
NP_005 MAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT
70 80 90 100 110 120
180 190 200 210 220 230
pF1KB7 AKAGHSDSDSGAELGPHPGGG-AVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQ
. : .:. :. ::: :. .:.: : . .:: :
NP_005 LLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG---AAAVGQRLESPGG---------A
130 140 150 160 170
240 250 260 270 280 290
pF1KB7 AGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMD-AFDVHEFDQYLPLGGPAP
::. : :.. .. ..: . .. .: . :. : : .: :
NP_005 AGG-------GYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQH------PGAGGAH
180 190 200 210 220
300 310 320 330 340 350
pF1KB7 PEPGQAYGGAYFHAGASPVWAHKSAP--SASASPTETGPPRPHIKTEQPSPGHYGDQPRG
:. :. . : : : :. : . . . .: . ::. :: : :
NP_005 PHAHPAHPHPH-HPHAHP---HNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYG
230 240 250 260 270
360 370 380 390 400
pF1KB7 SPDYGSCSG----QSSATPAAPAGPFA--GSQGDYGDLQASSYYGAYPGYAPGLYQYPCF
. .. .. :.::. :: :. : :. : :.: : :. : ::. . ::
NP_005 AAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPP--APAHSRAPCP
280 290 300 310 320 330
410 420 430 440
pF1KB7 HSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
. :. . : : . ::
NP_005 GDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI
340 350 360 370 380 390
>>NP_003098 (OMIM: 184430) transcription factor SOX-4 [H (474 aa)
initn: 500 init1: 403 opt: 442 Z-score: 283.9 bits: 61.8 E(85289): 4.5e-09
Smith-Waterman score: 448; 34.3% identity (59.6% similar) in 329 aa overlap (101-400:58-375)
80 90 100 110 120 130
pF1KB7 AVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNA
:.::::::::::.: :::. .: : .:::
NP_003 LGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNA
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB7 ELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGA
:.:: ::: :.::..:.: ::..::::::..: :.:::::.: ::..:.:...:.:.:
NP_003 EISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRP--RKKVKSGNANSSSSA
90 100 110 120 130 140
200 210 220 230
pF1KB7 ELGPHPG---------GGAVYKAEAGLGDGHHHGDHTGQTHGPP-TPPTTPKTELQQ-AG
. .:: ::. . . .: :... : : . : . :. :. .. ::
NP_003 AASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAG
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB7 ------AKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEF-DQYLPLG
.::. :: . .: . . . . ...: :. . . :..
NP_003 GAGGGVSKPHAKL----ILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYK
210 220 230 240 250 260
300 310 320 330 340
pF1KB7 GPAPPEPGQAYGGAYFHAG-ASPV--WAHKSAPSA---SASPTETGPPRPHIKTEQPS-P
. .: ..: ..: :. :.: :.:.. . .. : ..: .:: :
NP_003 ARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDP
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB7 -GHYGDQPRG-SPDYGSCSGQSSA--TPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPG
: : .. : ::: : ::.::: .::: .: : .: :..:.:.: :. ::
NP_003 LGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSP-ADHRG-YASLRAAS---PAPSSAPS
330 340 350 360 370
410 420 430 440
pF1KB7 LYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
NP_003 HASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNF
380 390 400 410 420 430
>>NP_060889 (OMIM: 137940,601618,607823) transcription f (384 aa)
initn: 487 init1: 397 opt: 435 Z-score: 280.9 bits: 60.9 E(85289): 6.6e-09
Smith-Waterman score: 446; 31.7% identity (48.2% similar) in 398 aa overlap (31-407:12-381)
10 20 30 40 50
pF1KB7 MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSP---AGSEGLGRAGVAVGGARGDPA
: ::. : . : : :. . : : : ::
NP_060 MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAG-PA
10 20 30 40
60 70 80 90 100 110
pF1KB7 EAADERFPACIRDAVSQVLKGYDWSLVPMPVRGG----GGGALKA--KPHVKRPMNAFMV
: :: : . : : : : : : .: . ...::::::::
NP_060 ALAAPAAPA------SPPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMV
50 60 70 80 90
120 130 140 150 160 170
pF1KB7 WAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKY
::. :..::.: : :::: ::: ::: :. :. .:::::::::::::::: .:::.:::
NP_060 WAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKY
100 110 120 130 140 150
180 190 200 210 220
pF1KB7 QPRRRKSAKAGHSDSDSG---AELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTH---GPP
.:::.:.:. .. . : :.: . : .: . . .. : : :
NP_060 RPRRKKQARKARR-LEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLGLP
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB7 TPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEF
:: .: :. . : . : : . . . . .::: . : . : .
NP_060 TPERSPLDGLEPGEAA--FFPPPAAPEDCALRPFRAPYAP-TELSRDPGGCYGA----PL
220 230 240 250 260
290 300 310 320 330 340
pF1KB7 DQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSP
. : . :: : : :: :. . .: : : :.. : :.
NP_060 AEALRTAPPAAPLAGLYYGTL----GTPGPYPGPLSPPPEAPPLESAEPL------GPAA
270 280 290 300 310
350 360 370 380 390
pF1KB7 GHYGDQPRGSPD-YGSCSGQSSATPAAPAGPFAGSQGDYGDL-----QASSYYGAYPGYA
..: : : .:: . : ::. :. . . : . :: .: .
NP_060 DLWADVDLTEFDQYLNCS---RTRPDAPGLPYHVALAKLGPRAMSCPEESSLISALSDAS
320 330 340 350 360 370
400 410 420 430 440
pF1KB7 PGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
..: :
NP_060 SAVYYSACISG
380
>>NP_003097 (OMIM: 184429,189960,206900) transcription f (317 aa)
initn: 387 init1: 387 opt: 433 Z-score: 280.7 bits: 60.6 E(85289): 6.8e-09
Smith-Waterman score: 441; 31.5% identity (56.0% similar) in 327 aa overlap (85-396:14-313)
60 70 80 90 100
pF1KB7 DPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGA---------LKAKP-HVKR
:. . ::::: : .: .:::
NP_003 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKR
10 20 30 40
110 120 130 140 150 160
pF1KB7 PMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKK
::::::::... :::.:.. :..::.:.:: :: :.::::.:::::..::.:::. : :
NP_003 PMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMK
50 60 70 80 90 100
170 180 190 200 210
pF1KB7 DHPDYKYQPRRR-KSAKAGHSDSDSGAELGPHPGGGAVYKAE---AGLGDG-HHHGDHTG
.::::::.:::. :. . . :. :.: ::... .. :::: : ... : .
NP_003 EHPDYKYRPRRKTKTLMKKDKYTLPGGLLAP--GGNSMASGVGVGAGLGAGVNQRMDSYA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB7 QTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDA
. .: . . . .: :. .: . : . :.: :. . : . ..
NP_003 HMNGWSNGSYSMMQDQLGYPQHPGLNAHG------AAQMQPMHRYDVSALQYNSMTSSQT
170 180 190 200 210
280 290 300 310 320 330
pF1KB7 FDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIK
:. :.:. :. .: . : .: : : :. : . ..:: .
NP_003 --------YMN-GSPT-------YSMSYSQQG-TPGMALGSMGSVVKSEASSSPPVVTSS
220 230 240 250
340 350 360 370 380 390
pF1KB7 TEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYA
... .: . :: : : ::::. ... . : . ... :. :
NP_003 SHSRAPCQAGDLRDMISMY--LPGAEVPEPAAPSRLHMSQHYQSGPVPGTAINGTLPLSH
260 270 280 290 300 310
400 410 420 430 440
pF1KB7 PGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
NP_003 M
>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [ (276 aa)
initn: 466 init1: 393 opt: 428 Z-score: 278.5 bits: 60.0 E(85289): 9e-09
Smith-Waterman score: 428; 34.4% identity (58.0% similar) in 262 aa overlap (98-346:2-247)
70 80 90 100 110 120
pF1KB7 IRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKP--HVKRPMNAFMVWAQAARRKLADQYP
.:: ::::::::::::..: :::.:.. :
NP_009 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENP
10 20 30
130 140 150 160 170 180
pF1KB7 HLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSD
..::.:.:: :: :.::.:::::::..::.:::..: :.::::::.:::. ..
NP_009 KMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLL---K
40 50 60 70 80
190 200 210 220 230 240
pF1KB7 SDSGAELGPHPGGGAVYKAEAGL--GDGHHHGDHTGQTHGPPTPPTTPKTELQQAGAK--
.:. : :. ::.. . .: : : : : : . : . ..:. :.:
NP_009 KDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV--PESLLANPEKAAAAAAAAAA
90 100 110 120 130 140
250 260 270 280 290
pF1KB7 ----PELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPP
:. . . .. . .: .:.. .:. .. ... :: :.
NP_009 RVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYAS-----SLGYPT--
150 160 170 180 190
300 310 320 330 340 350
pF1KB7 EPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPR---PHIKTEQPSPGHYGDQPRG
: .::. :.:. . : .: . . : : : : . ::::
NP_009 ----AGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYI
200 210 220 230 240 250
360 370 380 390 400 410
pF1KB7 SPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRP
NP_009 LLPGMGKPQLDPYPAAYAAAL
260 270
>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens] (233 aa)
initn: 400 init1: 377 opt: 413 Z-score: 270.4 bits: 58.3 E(85289): 2.5e-08
Smith-Waterman score: 430; 38.6% identity (62.8% similar) in 223 aa overlap (85-302:29-224)
60 70 80 90 100 110
pF1KB7 DPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAK-P--HVKRPMNAFMV
:. .:.:. : . : .::::::::::
NP_008 MALPGSSQDQAWSLEPPAATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMV
10 20 30 40 50
120 130 140 150 160 170
pF1KB7 WAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKY
:..: ::..:.: :..::.:.:: :: :.::.:.:::::::::.:::..: .:.:::::
NP_008 WSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKY
60 70 80 90 100 110
180 190 200 210 220
pF1KB7 QPRRR-KSAKAGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHG-PPTPPT
.:::. ::. :: : .: : .:: .. : :. : ..: ::.
NP_008 RPRRKAKSSGAGPSRCGQGR--GNLASGGPLW------GPGYA---TTQPSRGFGYRPPS
120 130 140 150 160
230 240 250 260 270 280
pF1KB7 TPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYL
. : . .. . :::. : . ... .:..:.. : . .::
NP_008 YSTAYLPGSYGSSHCKLEAPSPCSLPQSD--------PRLQGELLPT--------YTHYL
170 180 190 200 210
290 300 310 320 330 340
pF1KB7 PLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYG
: :.:.: .: :
NP_008 PPGSPTPYNPPLAGAPMPLTHL
220 230
446 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:23:25 2016 done: Fri Nov 4 09:23:27 2016
Total Scan time: 9.980 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]