Result of FASTA (omim) for
pF1KB7723
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7723, 430 aa
1>>>pF1KB7723 430 - 430 aa - 430 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6028+/-0.00035; mu= 16.3486+/- 0.022
mean_var=245.7885+/-48.968, 0's: 0 Z-trim(122.9): 82 B-trim: 0 in 0/59
Lambda= 0.081808
statistics sampled from 41570 (41678) to 41570 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.489), width: 16
Scan time: 11.060
The best scores are: opt bits E(85289)
NP_002577 (OMIM: 176311) pre-B-cell leukemia trans ( 430) 2886 353.3 6.9e-97
XP_016856884 (OMIM: 176310) PREDICTED: pre-B-cell ( 406) 1864 232.7 1.4e-60
NP_001191892 (OMIM: 176310) pre-B-cell leukemia tr ( 420) 1864 232.7 1.4e-60
NP_002576 (OMIM: 176310) pre-B-cell leukemia trans ( 430) 1864 232.7 1.4e-60
XP_005245286 (OMIM: 176310) PREDICTED: pre-B-cell ( 430) 1864 232.7 1.4e-60
NP_006186 (OMIM: 176312) pre-B-cell leukemia trans ( 434) 1836 229.4 1.4e-59
XP_016856885 (OMIM: 176310) PREDICTED: pre-B-cell ( 347) 1742 218.2 2.7e-56
NP_001191890 (OMIM: 176310) pre-B-cell leukemia tr ( 347) 1742 218.2 2.7e-56
NP_001317711 (OMIM: 176312) pre-B-cell leukemia tr ( 351) 1708 214.2 4.4e-55
NP_001128250 (OMIM: 176312) pre-B-cell leukemia tr ( 359) 1594 200.7 5e-51
XP_011507892 (OMIM: 176310) PREDICTED: pre-B-cell ( 462) 1511 191.1 5.1e-48
XP_005245285 (OMIM: 176310) PREDICTED: pre-B-cell ( 486) 1511 191.1 5.2e-48
NP_079521 (OMIM: 608127) pre-B-cell leukemia trans ( 374) 1497 189.3 1.4e-47
XP_006717194 (OMIM: 176312) PREDICTED: pre-B-cell ( 372) 1474 186.6 9.3e-47
XP_006717193 (OMIM: 176312) PREDICTED: pre-B-cell ( 455) 1474 186.7 1e-46
XP_016870275 (OMIM: 176312) PREDICTED: pre-B-cell ( 276) 1466 185.4 1.5e-46
XP_011507893 (OMIM: 176310) PREDICTED: pre-B-cell ( 403) 1389 176.6 1e-43
XP_011507894 (OMIM: 176310) PREDICTED: pre-B-cell ( 403) 1389 176.6 1e-43
XP_011517057 (OMIM: 176312) PREDICTED: pre-B-cell ( 380) 1232 158.0 3.7e-38
XP_016882816 (OMIM: 608127) PREDICTED: pre-B-cell ( 343) 1217 156.2 1.2e-37
XP_016882815 (OMIM: 608127) PREDICTED: pre-B-cell ( 357) 1217 156.2 1.2e-37
XP_011526622 (OMIM: 608127) PREDICTED: pre-B-cell ( 391) 1217 156.3 1.3e-37
XP_016882817 (OMIM: 608127) PREDICTED: pre-B-cell ( 327) 1169 150.5 6e-36
XP_006722974 (OMIM: 608127) PREDICTED: pre-B-cell ( 288) 1124 145.1 2.2e-34
XP_011526624 (OMIM: 608127) PREDICTED: pre-B-cell ( 288) 1124 145.1 2.2e-34
XP_016882818 (OMIM: 608127) PREDICTED: pre-B-cell ( 209) 762 102.2 1.4e-21
XP_006717196 (OMIM: 176312) PREDICTED: pre-B-cell ( 274) 615 85.0 2.6e-16
XP_016882819 (OMIM: 608127) PREDICTED: pre-B-cell ( 188) 297 47.2 4.2e-05
>>NP_002577 (OMIM: 176311) pre-B-cell leukemia transcrip (430 aa)
initn: 2886 init1: 2886 opt: 2886 Z-score: 1860.5 bits: 353.3 E(85289): 6.9e-97
Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 430 aa overlap (1-430:1-430)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEG
370 380 390 400 410 420
430
pF1KB7 PGSVHSDTSN
::::::::::
NP_002 PGSVHSDTSN
430
>>XP_016856884 (OMIM: 176310) PREDICTED: pre-B-cell leuk (406 aa)
initn: 2031 init1: 1142 opt: 1864 Z-score: 1208.8 bits: 232.7 E(85289): 1.4e-60
Smith-Waterman score: 1930; 78.5% identity (91.7% similar) in 386 aa overlap (23-397:15-397)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
: : :: : .::. : ::: :::::::::::
XP_016 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::.::::::::::::::.::::::::: ::::..:::::.:::::::::
XP_016 MTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
::::::::::::::::::::::::::::. : :::.::::::.::.:::.:::.::::::
XP_016 MLLAEGVAGPEKGGGSAAAAAAAAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYE
120 130 140 150 160
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::::::::::.:::::::::::::::::::
XP_016 QACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::.:::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 FLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
230 240 250 260 270 280
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLG
:::::::::::::::::.::::..:. ..: :...::. :.::::..:::.:.:::.:..
XP_016 RYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMS
290 300 310 320 330 340
360 370 380 390 400
pF1KB7 MPGLNGDSYSA--------SQVESLRHSMGP-GGYGDNLGGGQMYSPREMRANGSWQEAV
. .::::::.. :::..::: .. :::.:.:...:::::.
XP_016 VQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISEIARTY
350 360 370 380 390 400
410 420 430
pF1KB7 TPSSVTSPTEGPGSVHSDTSN
>>NP_001191892 (OMIM: 176310) pre-B-cell leukemia transc (420 aa)
initn: 1997 init1: 1142 opt: 1864 Z-score: 1208.7 bits: 232.7 E(85289): 1.4e-60
Smith-Waterman score: 1930; 78.5% identity (91.7% similar) in 386 aa overlap (23-397:15-397)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
: : :: : .::. : ::: :::::::::::
NP_001 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::.::::::::::::::.::::::::: ::::..:::::.:::::::::
NP_001 MTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
::::::::::::::::::::::::::::. : :::.::::::.::.:::.:::.::::::
NP_001 MLLAEGVAGPEKGGGSAAAAAAAAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYE
120 130 140 150 160
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::::::::::.:::::::::::::::::::
NP_001 QACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::.:::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 FLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
230 240 250 260 270 280
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLG
:::::::::::::::::.::::..:. ..: :...::. :.::::..:::.:.:::.:..
NP_001 RYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMS
290 300 310 320 330 340
360 370 380 390 400
pF1KB7 MPGLNGDSYSA--------SQVESLRHSMGP-GGYGDNLGGGQMYSPREMRANGSWQEAV
. .::::::.. :::..::: .. :::.:.:...:::::.
NP_001 VQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISHLPRHPRQA
350 360 370 380 390 400
410 420 430
pF1KB7 TPSSVTSPTEGPGSVHSDTSN
NP_001 HYHFRLPTWHP
410 420
>>NP_002576 (OMIM: 176310) pre-B-cell leukemia transcrip (430 aa)
initn: 2181 init1: 1142 opt: 1864 Z-score: 1208.6 bits: 232.7 E(85289): 1.4e-60
Smith-Waterman score: 2114; 78.8% identity (91.9% similar) in 419 aa overlap (23-430:15-430)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
: : :: : .::. : ::: :::::::::::
NP_002 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::.::::::::::::::.::::::::: ::::..:::::.:::::::::
NP_002 MTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
::::::::::::::::::::::::::::. : :::.::::::.::.:::.:::.::::::
NP_002 MLLAEGVAGPEKGGGSAAAAAAAAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYE
120 130 140 150 160
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::::::::::.:::::::::::::::::::
NP_002 QACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::.:::::.::::::::::::::::::::::::::::::::::::::::::
NP_002 FLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
230 240 250 260 270 280
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLG
:::::::::::::::::.::::..:. ..: :...::. :.::::..:::.:.:::.:..
NP_002 RYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMS
290 300 310 320 330 340
360 370 380 390 400
pF1KB7 MPGLNGDSYSA--------SQVESLRHSMGP-GGYGDNLGGGQMYSPREMRANGSWQEAV
. .::::::.. :::..::: .. :::.:.:...:::::. . :::.::.:.
NP_002 VQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDAT
350 360 370 380 390 400
410 420 430
pF1KB7 TPSSVTSPTEGPGSVHSDTSN
:::::::::::::::::::::
NP_002 TPSSVTSPTEGPGSVHSDTSN
410 420 430
>>XP_005245286 (OMIM: 176310) PREDICTED: pre-B-cell leuk (430 aa)
initn: 2181 init1: 1142 opt: 1864 Z-score: 1208.6 bits: 232.7 E(85289): 1.4e-60
Smith-Waterman score: 2114; 78.8% identity (91.9% similar) in 419 aa overlap (23-430:15-430)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
: : :: : .::. : ::: :::::::::::
XP_005 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::.::::::::::::::.::::::::: ::::..:::::.:::::::::
XP_005 MTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
::::::::::::::::::::::::::::. : :::.::::::.::.:::.:::.::::::
XP_005 MLLAEGVAGPEKGGGSAAAAAAAAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYE
120 130 140 150 160
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::::::::::.:::::::::::::::::::
XP_005 QACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::.:::::.::::::::::::::::::::::::::::::::::::::::::
XP_005 FLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
230 240 250 260 270 280
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLG
:::::::::::::::::.::::..:. ..: :...::. :.::::..:::.:.:::.:..
XP_005 RYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMS
290 300 310 320 330 340
360 370 380 390 400
pF1KB7 MPGLNGDSYSA--------SQVESLRHSMGP-GGYGDNLGGGQMYSPREMRANGSWQEAV
. .::::::.. :::..::: .. :::.:.:...:::::. . :::.::.:.
XP_005 VQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDAT
350 360 370 380 390 400
410 420 430
pF1KB7 TPSSVTSPTEGPGSVHSDTSN
:::::::::::::::::::::
XP_005 TPSSVTSPTEGPGSVHSDTSN
410 420 430
>>NP_006186 (OMIM: 176312) pre-B-cell leukemia transcrip (434 aa)
initn: 1537 init1: 1106 opt: 1836 Z-score: 1190.7 bits: 229.4 E(85289): 1.4e-59
Smith-Waterman score: 2090; 78.0% identity (90.5% similar) in 419 aa overlap (26-430:23-434)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
:: . :: : : :. : ::::::::.::
NP_006 MDDQSRMLQTLAGVNLAGHSVQGGMALPP----PPHGHEGADGDGRKQDIGDILHQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::::::::::::::::::::::::::::::::..:::.: :::::::::
NP_006 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
:::::::.:::::::::::::::::::: : ::::::::::.::.:::.:::.::::::
NP_006 MLLAEGVSGPEKGGGSAAAAAAAAASGG--SSDNSIEHSDYRAKLTQIRQIYHTELEKYE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::.:::::::.:::::::::::::::::::
NP_006 QACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::::::::.::::::::::::::::::::::::::.:::::::::::::::
NP_006 FLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRI
240 250 260 270 280 290
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQG-----GHSRTSSPTPPSSAGSGGSFNLSGSGDM
::::::::::::::.::.::::..... ...:.::: :.: ::.::::: .::::
NP_006 RYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDM
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 FLGMPGLNGDSYSASQV--------ESLRHSMGP-GGYGDNLGGGQMYSPREMRANGSWQ
:..: .::::::..::: ..::: .. :::.:.:::...:::... :::.::
NP_006 FMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQ
360 370 380 390 400 410
410 420 430
pF1KB7 EAVTPSSVTSPTEGPGSVHSDTSN
.:.:::::::::::::::::::::
NP_006 DATTPSSVTSPTEGPGSVHSDTSN
420 430
>>XP_016856885 (OMIM: 176310) PREDICTED: pre-B-cell leuk (347 aa)
initn: 1161 init1: 1161 opt: 1742 Z-score: 1131.7 bits: 218.2 E(85289): 2.7e-56
Smith-Waterman score: 1742; 84.5% identity (93.8% similar) in 322 aa overlap (23-342:15-333)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
: : :: : .::. : ::: :::::::::::
XP_016 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::.::::::::::::::.::::::::: ::::..:::::.:::::::::
XP_016 MTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
::::::::::::::::::::::::::::. : :::.::::::.::.:::.:::.::::::
XP_016 MLLAEGVAGPEKGGGSAAAAAAAAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYE
120 130 140 150 160
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::::::::::.:::::::::::::::::::
XP_016 QACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::.:::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 FLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
230 240 250 260 270 280
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLG
:::::::::::::::::.::::..:. ..: :...::. :.:::
XP_016 RYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGGYPSPCYQPDRRIQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 MPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPT
>>NP_001191890 (OMIM: 176310) pre-B-cell leukemia transc (347 aa)
initn: 1161 init1: 1161 opt: 1742 Z-score: 1131.7 bits: 218.2 E(85289): 2.7e-56
Smith-Waterman score: 1742; 84.5% identity (93.8% similar) in 322 aa overlap (23-342:15-333)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
: : :: : .::. : ::: :::::::::::
NP_001 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::.::::::::::::::.::::::::: ::::..:::::.:::::::::
NP_001 MTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
::::::::::::::::::::::::::::. : :::.::::::.::.:::.:::.::::::
NP_001 MLLAEGVAGPEKGGGSAAAAAAAAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYE
120 130 140 150 160
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::::::::::.:::::::::::::::::::
NP_001 QACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::.:::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 FLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
230 240 250 260 270 280
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLG
:::::::::::::::::.::::..:. ..: :...::. :.:::
NP_001 RYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGGYPSPCYQPDRRIQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 MPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPT
>>NP_001317711 (OMIM: 176312) pre-B-cell leukemia transc (351 aa)
initn: 1823 init1: 1097 opt: 1708 Z-score: 1109.9 bits: 214.2 E(85289): 4.4e-55
Smith-Waterman score: 1708; 82.6% identity (92.2% similar) in 322 aa overlap (26-342:23-338)
10 20 30 40 50 60
pF1KB7 MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
:: . :: : : :. : ::::::::.::
NP_001 MDDQSRMLQTLAGVNLAGHSVQGGMALPP----PPHGHEGADGDGRKQDIGDILHQI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
:::::::::::::::::::::::::::::::::::::::::::..:::.: :::::::::
NP_001 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
:::::::.:::::::::::::::::::: : ::::::::::.::.:::.:::.::::::
NP_001 MLLAEGVSGPEKGGGSAAAAAAAAASGG--SSDNSIEHSDYRAKLTQIRQIYHTELEKYE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
::::::::::::::::::::::..:::.::::.:::::::.:::::::::::::::::::
NP_001 QACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
:::::::::::::::::.::::::::::::::::::::::::::.:::::::::::::::
NP_001 FLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRI
240 250 260 270 280 290
310 320 330 340 350
pF1KB7 RYKKNIGKFQEEANIYAVKTAVSVTQG-----GHSRTSSPTPPSSAGSGGSFNLSGSGDM
::::::::::::::.::.::::..... ...:.::: :.:.:
NP_001 RYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGGYPPSCYQSDGRLQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 FLGMPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVT
>>NP_001128250 (OMIM: 176312) pre-B-cell leukemia transc (359 aa)
initn: 1495 init1: 1106 opt: 1594 Z-score: 1037.1 bits: 200.7 E(85289): 5e-51
Smith-Waterman score: 1848; 79.3% identity (92.8% similar) in 362 aa overlap (83-430:1-359)
60 70 80 90 100 110
pF1KB7 IGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVD
:::::::::::::::::::::..:::.: :
NP_001 MKPALFSVLCEIKEKTGLSIRGAQEEDPPD
10 20 30
120 130 140 150 160 170
pF1KB7 PQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIY
:::::::::::::::.:::::::::::::::::::: : ::::::::::.::.:::.::
NP_001 PQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGG--SSDNSIEHSDYRAKLTQIRQIY
40 50 60 70 80
180 190 200 210 220 230
pF1KB7 HSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCE
:.::::::::::::::::::::::::::::..:::.::::.:::::::.:::::::::::
NP_001 HTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCE
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB7 AVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVS
:::::::::::::::::::::::::.::::::::::::::::::::::::::.:::::::
NP_001 AVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVS
150 160 170 180 190 200
300 310 320 330 340
pF1KB7 NWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQG-----GHSRTSSPTPPSSAGSGGSF
::::::::::::::::::::::.::.::::..... ...:.::: :.: ::.:::
NP_001 NWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSF
210 220 230 240 250 260
350 360 370 380 390
pF1KB7 NLSGSGDMFLGMPGLNGDSYSASQV--------ESLRHSMGP-GGYGDNLGGGQMYSPRE
:: .:::::..: .::::::..::: ..::: .. :::.:.:::...:::..
NP_001 NLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHN
270 280 290 300 310 320
400 410 420 430
pF1KB7 MRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN
. :::.::.:.:::::::::::::::::::::
NP_001 LNANGGWQDATTPSSVTSPTEGPGSVHSDTSN
330 340 350
430 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:07:33 2016 done: Fri Nov 4 22:07:35 2016
Total Scan time: 11.060 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]