Result of FASTA (omim) for
pF1KB7715
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7715, 426 aa
1>>>pF1KB7715 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4409+/-0.000305; mu= 17.4400+/- 0.019
mean_var=75.5555+/-14.593, 0's: 0 Z-trim(118.2): 48 B-trim: 0 in 0/57
Lambda= 0.147551
statistics sampled from 30809 (30859) to 30809 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.362), width: 16
Scan time: 9.560
The best scores are: opt bits E(85289)
NP_002154 (OMIM: 601565,614893,614894) interferon ( 426) 2959 638.9 7.1e-183
XP_016878688 (OMIM: 601565,614893,614894) PREDICTE ( 222) 1526 333.7 2.8e-91
XP_006715153 (OMIM: 601900,611724) PREDICTED: inte ( 415) 680 153.8 7.6e-37
NP_006075 (OMIM: 147574) interferon regulatory fac ( 393) 678 153.3 9.8e-37
NP_001182215 (OMIM: 601900,611724) interferon regu ( 450) 638 144.9 4e-34
NP_002451 (OMIM: 601900,611724) interferon regulat ( 451) 638 144.9 4e-34
XP_016882256 (OMIM: 603734,616532) PREDICTED: inte ( 427) 476 110.4 9.2e-24
XP_016882255 (OMIM: 603734,616532) PREDICTED: inte ( 427) 476 110.4 9.2e-24
NP_001562 (OMIM: 603734,616532) interferon regulat ( 427) 476 110.4 9.2e-24
NP_002190 (OMIM: 147576) interferon regulatory fac ( 349) 398 93.7 7.8e-19
XP_011541680 (OMIM: 147575,211980,613659) PREDICTE ( 284) 395 93.0 1e-18
NP_001193625 (OMIM: 119300,119500,607199,608864) i ( 372) 396 93.3 1.1e-18
NP_002189 (OMIM: 147575,211980,613659) interferon ( 325) 395 93.1 1.2e-18
NP_006138 (OMIM: 119300,119500,607199,608864) inte ( 467) 391 92.3 2.8e-18
NP_001092100 (OMIM: 607218,612245,612251) interfer ( 498) 390 92.1 3.4e-18
NP_001092097 (OMIM: 607218,612245,612251) interfer ( 498) 390 92.1 3.4e-18
NP_116032 (OMIM: 607218,612245,612251) interferon ( 498) 390 92.1 3.4e-18
XP_011514463 (OMIM: 607218,612245,612251) PREDICTE ( 504) 387 91.5 5.3e-18
NP_001229381 (OMIM: 607218,612245,612251) interfer ( 412) 384 90.8 7.1e-18
XP_011514466 (OMIM: 607218,612245,612251) PREDICTE ( 488) 384 90.8 8.1e-18
XP_011514464 (OMIM: 607218,612245,612251) PREDICTE ( 488) 384 90.8 8.1e-18
XP_011514465 (OMIM: 607218,612245,612251) PREDICTE ( 488) 384 90.8 8.1e-18
XP_011514462 (OMIM: 607218,612245,612251) PREDICTE ( 514) 384 90.8 8.4e-18
XP_005250374 (OMIM: 607218,612245,612251) PREDICTE ( 514) 384 90.8 8.4e-18
XP_006716037 (OMIM: 607218,612245,612251) PREDICTE ( 514) 384 90.8 8.4e-18
NP_001092099 (OMIM: 607218,612245,612251) interfer ( 514) 384 90.8 8.4e-18
XP_011514461 (OMIM: 607218,612245,612251) PREDICTE ( 514) 384 90.8 8.4e-18
XP_011514460 (OMIM: 607218,612245,612251) PREDICTE ( 514) 384 90.8 8.4e-18
XP_006723260 (OMIM: 603734,616532) PREDICTED: inte ( 452) 374 88.7 3.3e-17
XP_006723261 (OMIM: 603734,616532) PREDICTED: inte ( 452) 374 88.7 3.3e-17
NP_001184051 (OMIM: 603734,616532) interferon regu ( 452) 374 88.7 3.3e-17
NP_001184052 (OMIM: 603734,616532) interferon regu ( 392) 312 75.4 2.8e-13
NP_001184053 (OMIM: 603734,616532) interferon regu ( 300) 294 71.5 3.2e-12
NP_001184055 (OMIM: 603734,616532) interferon regu ( 281) 216 54.9 3e-07
NP_001184054 (OMIM: 603734,616532) interferon regu ( 281) 216 54.9 3e-07
XP_006723263 (OMIM: 603734,616532) PREDICTED: inte ( 417) 210 53.7 1e-06
XP_005252966 (OMIM: 605047,616345) PREDICTED: inte ( 487) 210 53.8 1.1e-06
XP_005252964 (OMIM: 605047,616345) PREDICTED: inte ( 515) 210 53.8 1.2e-06
XP_005252963 (OMIM: 605047,616345) PREDICTED: inte ( 516) 210 53.8 1.2e-06
NP_004022 (OMIM: 605047,616345) interferon regulat ( 516) 210 53.8 1.2e-06
NP_004020 (OMIM: 605047,616345) interferon regulat ( 474) 209 53.6 1.3e-06
XP_011518368 (OMIM: 605047,616345) PREDICTED: inte ( 502) 209 53.6 1.4e-06
NP_001563 (OMIM: 605047,616345) interferon regulat ( 503) 209 53.6 1.4e-06
XP_016873163 (OMIM: 605047,616345) PREDICTED: inte ( 210) 180 47.2 4.9e-05
>>NP_002154 (OMIM: 601565,614893,614894) interferon regu (426 aa)
initn: 2959 init1: 2959 opt: 2959 Z-score: 3404.1 bits: 638.9 E(85289): 7.1e-183
Smith-Waterman score: 2959; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE
370 380 390 400 410 420
pF1KB7 NQQITV
::::::
NP_002 NQQITV
>>XP_016878688 (OMIM: 601565,614893,614894) PREDICTED: i (222 aa)
initn: 1526 init1: 1526 opt: 1526 Z-score: 1759.6 bits: 333.7 E(85289): 2.8e-91
Smith-Waterman score: 1526; 100.0% identity (100.0% similar) in 222 aa overlap (205-426:1-222)
180 190 200 210 220 230
pF1KB7 PDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQP
::::::::::::::::::::::::::::::
XP_016 MVISFYYGGKLVGQATTTCPEGCRLSLSQP
10 20 30
240 250 260 270 280 290
pF1KB7 GLPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQ
40 50 60 70 80 90
300 310 320 330 340 350
pF1KB7 GRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEF
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB7 PDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQ
160 170 180 190 200 210
420
pF1KB7 RSFFRENQQITV
::::::::::::
XP_016 RSFFRENQQITV
220
>>XP_006715153 (OMIM: 601900,611724) PREDICTED: interfer (415 aa)
initn: 1088 init1: 388 opt: 680 Z-score: 782.4 bits: 153.8 E(85289): 7.6e-37
Smith-Waterman score: 1052; 46.9% identity (66.2% similar) in 390 aa overlap (6-386:20-386)
10 20 30 40
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQ
:. .::::::.::::. ::::.:::::::.:::::::::::
XP_006 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 DYNQEVDASIFKAWAVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISE
:::.: ::..:::::.:::::.:: :: .: ::::::::::::: ::::...:::::::.
XP_006 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 PYKVYRIVPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPS--VDDYMGMIKRSP
:::::::::: .: :. . : . . :. : .::
XP_006 PYKVYRIVPEGAKK---GAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYM-------
130 140 150 160 170
170 180 190 200 210
pF1KB7 SPP-EACRSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFS---QMVISFYYGGKLVGQA
:: . . .:: . :.. : . . : .. : .:: :: .
XP_006 MPPLDRSWRDYVPDQPHPEIPYQCPMTFGPRGHHWQGPACENDCRLHICLYYREILVKEL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 TTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFP-PADAIPSERQRQVTRKLFGHLERGV
::. :::::.: .. : .:. : :: : : . ::. .::..::::::
XP_006 TTSSPEGCRISHGHT-------YDASNLDQVLFPYPED----NGQRKNIEKLLSHLERGV
240 250 260 270
280 290 300 310 320 330
pF1KB7 LLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQ
.: . .:...:::::.:.. .: ..:. ::::::::.. ..:::.::. ::: : .
XP_006 VLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFDTQQFLSELQAFAHHG
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB7 GRLPDGRVVLCFGEEFPDMAPLRS-KLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEP
:: .:.::::::::: : :. ::: ...: : .::: : .. :
XP_006 RSLPRFQVTLCFGEEFPD--PQRQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYDLPEH
340 350 360 370 380 390
400 410 420
pF1KB7 PPDQVFRMFPDICASHQRSFFRENQQITV
XP_006 ISNPEDYHRSIRHSSIQE
400 410
>>NP_006075 (OMIM: 147574) interferon regulatory factor (393 aa)
initn: 728 init1: 525 opt: 678 Z-score: 780.5 bits: 153.3 E(85289): 9.8e-37
Smith-Waterman score: 739; 34.3% identity (64.9% similar) in 396 aa overlap (8-387:10-388)
10 20 30 40 50
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFK
:.::.:..::..:...::. :.. :.:::::::::::::. .. ::..::
NP_006 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 AWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQ
:::.::::.:::: . ::.:::::::::::: .:.:: .:...:..::::::...:
NP_006 AWAIFKGKYKEGDTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLLPPGIV
70 80 90 100 110 120
120 130 140 150 160
pF1KB7 KCKLGVATAGCVNEVTEMECGRSEIDELIKE----PSV-DDYMGMIKRSPSPPE------
. . :. . . . . :.: .. ... ::: .: .. ... :
NP_006 SGQPGTQKVPSKRQHSSVSSERKEEEDAMQNCTLSPSVLQDSLNNEEEGASGGAVHSDIG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 ACRSQLLPDWWAQQPSTGVPLVTGYTTYD---AHHSAFSQMVISFYYGGKLVGQATTTCP
. :. :. .: .:. . . . .: ....: :.:..::.: .
NP_006 SSSSSSSPEPQEVTDTTEAPFQGDQRSLEFLLPPEPDYS-LLLTFIYNGRVVGEAQVQSL
190 200 210 220 230
230 240 250 260 270 280
pF1KB7 EGCRLSLSQPGLPGTKLYGPEGLELVRFP-PADAIPSERQRQVTRKLFGHLERGVLLHSS
. ::: ...:. :.. ..: : :: :. :..: :...::::.:. :.
NP_006 D-CRL-VAEPS--GSE----SSMEQVLFPKPGPLEPTQR-------LLSQLERGILVASN
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 RQGVFVKRLCQGRV-FCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLP
.:.::.::: . . . .: : :. : .: :..: :. : :.: ..... : :
NP_006 PRGLFVQRLCPIPISWNAPQAPPGPG-PHLLPSNECVELFRTAYFCRDLVRYFQGLGPPP
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 DGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQV
.:.: : :: . ..:: :..:: ..: : :.. .. .:
NP_006 KFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQTPEQQAAILSLV
350 360 370 380 390
410 420
pF1KB7 FRMFPDICASHQRSFFRENQQITV
>>NP_001182215 (OMIM: 601900,611724) interferon regulato (450 aa)
initn: 1103 init1: 388 opt: 638 Z-score: 733.6 bits: 144.9 E(85289): 4e-34
Smith-Waterman score: 1044; 45.3% identity (65.5% similar) in 417 aa overlap (6-386:20-421)
10 20 30 40
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQ
:. .::::::.::::. ::::.:::::::.:::::::::::
NP_001 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 DYNQEVDASIFKAWAVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISE
:::.: ::..:::::.:::::.:: :: .: ::::::::::::: ::::...:::::::.
NP_001 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
110 120 130 140 150
pF1KB7 PYKVYRIVPEEEQKC--KLGV-----ATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGM
:::::::::: .: .: . . . . .: . ... . . : .. .
NP_001 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQVHNYMMPPLDRSWRDY
130 140 150 160 170 180
160 170 180 190
pF1KB7 IKRSPSP--PEACRSQLLP---DW---------------WAQQP----STGVPLVTGYTT
. .: : : : . : : .: : . ::: : .
NP_001 VPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVP--TEPSI
190 200 210 220 230
200 210 220 230 240 250
pF1KB7 YDAHHSAFS--QMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRF
.:. ::: .. : .:: :: . ::. :::::.: .. : .:. : :
NP_001 RSAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHT-------YDASNLDQVLF
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB7 P-PADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPN
: : : . ::. .::..::::::.: . .:...:::::.:.. .: ..:. :::
NP_001 PYPED----NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPN
300 310 320 330 340
320 330 340 350 360 370
pF1KB7 KLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPLRS-KLILVQIE
:::::.. ..:::.::. ::: : . :: .:.::::::::: : :. ::: ...:
NP_001 KLERDQTCKLFDTQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPD--PQRQRKLITAHVE
350 360 370 380 390 400
380 390 400 410 420
pF1KB7 QLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRENQQITV
: .::: : .. :
NP_001 PLLARQLYYFAQQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
410 420 430 440 450
>>NP_002451 (OMIM: 601900,611724) interferon regulatory (451 aa)
initn: 1103 init1: 388 opt: 638 Z-score: 733.6 bits: 144.9 E(85289): 4e-34
Smith-Waterman score: 1040; 45.6% identity (63.7% similar) in 421 aa overlap (6-386:20-422)
10 20 30 40
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQ
:. .::::::.::::. ::::.:::::::.:::::::::::
NP_002 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 DYNQEVDASIFKAWAVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISE
:::.: ::..:::::.:::::.:: :: .: ::::::::::::: ::::...:::::::.
NP_002 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
110 120 130 140 150
pF1KB7 PYKVYRIVPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPS--VDDYM-------
:::::::::: .: :. . : . . :. : .::
NP_002 PYKVYRIVPEGAKK---GAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRS
130 140 150 160 170
160 170 180 190
pF1KB7 --GMIKRSPSP--PEACRSQLLP---DW---------------WAQQP----STGVPLVT
.. .: : : : . : : .: : . ::: :
NP_002 WRDYVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVP--T
180 190 200 210 220 230
200 210 220 230 240
pF1KB7 GYTTYDAHHSAFS--QMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLE
. .:. ::: .. : .:: :: . ::. :::::.: .. : .:.
NP_002 EPSIRSAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHT-------YDASNLD
240 250 260 270 280
250 260 270 280 290 300
pF1KB7 LVRFP-PADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCK
: :: : : . ::. .::..::::::.: . .:...:::::.:.. .: ..:.
NP_002 QVLFPYPED----NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCN
290 300 310 320 330 340
310 320 330 340 350 360
pF1KB7 GRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPLRS-KLIL
::::::::.. ..:::.::. ::: : . :: .:.::::::::: : :. :::
NP_002 DRPNKLERDQTCKLFDTQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPD--PQRQRKLIT
350 360 370 380 390 400
370 380 390 400 410 420
pF1KB7 VQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRENQQITV
...: : .::: : .. :
NP_002 AHVEPLLARQLYYFAQQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
410 420 430 440 450
>>XP_016882256 (OMIM: 603734,616532) PREDICTED: interfer (427 aa)
initn: 263 init1: 196 opt: 476 Z-score: 547.6 bits: 110.4 E(85289): 9.2e-24
Smith-Waterman score: 480; 28.1% identity (54.3% similar) in 409 aa overlap (9-390:7-387)
10 20 30 40 50 60
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
:. ::. :.: .. :. : :. .. :::::::. .:: .:: : .::.::
XP_016 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAW
10 20 30 40 50
70 80 90 100 110
pF1KB7 AVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQK
: : . : :: . ::: .: :::.. .. . :::. : .:.:.:..:
XP_016 AEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSK-DPHDPHKIYEFVNS----
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 CKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSP----------PEAC
::. . . . . : : : .: .:. .: . .: : :: :
XP_016 ---GVGDFSQPDTSPDTNGGGSTSDT--QEDILDELLGNMVLAPLPDPGPPSLAVAPEPC
120 130 140 150 160
170 180 190 200 210 220
pF1KB7 RSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVI---------SFYYGGKLVGQAT
. : ..:: : : . . .. ...... . .: :. : : :
XP_016 PQPL------RSPSLDNP--TPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQT
170 180 190 200 210
230 240 250 260 270
pF1KB7 TTCPEGCRLSLSQPG---LPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERG
.:::: :: :. : ::: . :. :. .. .. . .:.... : :
XP_016 ISCPEGLRLVGSEVGDRTLPGWPVTLPD--------PGMSLTDRGVMSYVRHVLSCLGGG
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB7 VLLHSSRQGVFVKRL--CQGRVFCSGNAVVCKGR-PN-KLERDEVVQVFDTSQFFRELQQ
. : . : ....:: :. : . . .:. :. .. .:. ::: . :. .:
XP_016 LALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLIT
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB7 FYNSQGRLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQA
: ...:: : . .: :: .:. : ..:..:.. .: :.: : . ::.:.
XP_016 FTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMA-RVGGASSLENT
340 350 360 370 380 390
400 410 420
pF1KB7 PEEPPPDQVFRMFPDICASHQRSFFRENQQITV
XP_016 VDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES
400 410 420
>>XP_016882255 (OMIM: 603734,616532) PREDICTED: interfer (427 aa)
initn: 263 init1: 196 opt: 476 Z-score: 547.6 bits: 110.4 E(85289): 9.2e-24
Smith-Waterman score: 480; 28.1% identity (54.3% similar) in 409 aa overlap (9-390:7-387)
10 20 30 40 50 60
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
:. ::. :.: .. :. : :. .. :::::::. .:: .:: : .::.::
XP_016 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAW
10 20 30 40 50
70 80 90 100 110
pF1KB7 AVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQK
: : . : :: . ::: .: :::.. .. . :::. : .:.:.:..:
XP_016 AEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSK-DPHDPHKIYEFVNS----
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 CKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSP----------PEAC
::. . . . . : : : .: .:. .: . .: : :: :
XP_016 ---GVGDFSQPDTSPDTNGGGSTSDT--QEDILDELLGNMVLAPLPDPGPPSLAVAPEPC
120 130 140 150 160
170 180 190 200 210 220
pF1KB7 RSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVI---------SFYYGGKLVGQAT
. : ..:: : : . . .. ...... . .: :. : : :
XP_016 PQPL------RSPSLDNP--TPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQT
170 180 190 200 210
230 240 250 260 270
pF1KB7 TTCPEGCRLSLSQPG---LPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERG
.:::: :: :. : ::: . :. :. .. .. . .:.... : :
XP_016 ISCPEGLRLVGSEVGDRTLPGWPVTLPD--------PGMSLTDRGVMSYVRHVLSCLGGG
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB7 VLLHSSRQGVFVKRL--CQGRVFCSGNAVVCKGR-PN-KLERDEVVQVFDTSQFFRELQQ
. : . : ....:: :. : . . .:. :. .. .:. ::: . :. .:
XP_016 LALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLIT
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB7 FYNSQGRLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQA
: ...:: : . .: :: .:. : ..:..:.. .: :.: : . ::.:.
XP_016 FTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMA-RVGGASSLENT
340 350 360 370 380 390
400 410 420
pF1KB7 PEEPPPDQVFRMFPDICASHQRSFFRENQQITV
XP_016 VDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES
400 410 420
>>NP_001562 (OMIM: 603734,616532) interferon regulatory (427 aa)
initn: 263 init1: 196 opt: 476 Z-score: 547.6 bits: 110.4 E(85289): 9.2e-24
Smith-Waterman score: 480; 28.1% identity (54.3% similar) in 409 aa overlap (9-390:7-387)
10 20 30 40 50 60
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
:. ::. :.: .. :. : :. .. :::::::. .:: .:: : .::.::
NP_001 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAW
10 20 30 40 50
70 80 90 100 110
pF1KB7 AVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQK
: : . : :: . ::: .: :::.. .. . :::. : .:.:.:..:
NP_001 AEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSK-DPHDPHKIYEFVNS----
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 CKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSP----------PEAC
::. . . . . : : : .: .:. .: . .: : :: :
NP_001 ---GVGDFSQPDTSPDTNGGGSTSDT--QEDILDELLGNMVLAPLPDPGPPSLAVAPEPC
120 130 140 150 160
170 180 190 200 210 220
pF1KB7 RSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVI---------SFYYGGKLVGQAT
. : ..:: : : . . .. ...... . .: :. : : :
NP_001 PQPL------RSPSLDNP--TPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQT
170 180 190 200 210
230 240 250 260 270
pF1KB7 TTCPEGCRLSLSQPG---LPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERG
.:::: :: :. : ::: . :. :. .. .. . .:.... : :
NP_001 ISCPEGLRLVGSEVGDRTLPGWPVTLPD--------PGMSLTDRGVMSYVRHVLSCLGGG
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB7 VLLHSSRQGVFVKRL--CQGRVFCSGNAVVCKGR-PN-KLERDEVVQVFDTSQFFRELQQ
. : . : ....:: :. : . . .:. :. .. .:. ::: . :. .:
NP_001 LALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLIT
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB7 FYNSQGRLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQA
: ...:: : . .: :: .:. : ..:..:.. .: :.: : . ::.:.
NP_001 FTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMA-RVGGASSLENT
340 350 360 370 380 390
400 410 420
pF1KB7 PEEPPPDQVFRMFPDICASHQRSFFRENQQITV
NP_001 VDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES
400 410 420
>>NP_002190 (OMIM: 147576) interferon regulatory factor (349 aa)
initn: 403 init1: 221 opt: 398 Z-score: 459.1 bits: 93.7 E(85289): 7.8e-19
Smith-Waterman score: 398; 46.6% identity (72.4% similar) in 116 aa overlap (9-123:7-122)
10 20 30 40 50 60
pF1KB7 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
:.: :: :::.:. ::: : :.::..:.::: ::... .. : :: .:. :
NP_002 MPVERMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNW
10 20 30 40 50
70 80 90 100 110
pF1KB7 AVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQK
:. :: . : :: .: :::. .:::.:. ::.::: :.: .. ..:::..: :.
NP_002 AIHTGKHQPGVDKPDPKTWKANFRCAMNSLPDIEEVKDKSIKKGNNAFRVYRMLPLSERP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 CKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWA
: :
NP_002 SKKGKKPKTEKEDKVKHIKQEPVESSLGLSNGVSDLSPEYAVLTSTIKNEVDSTVNIIVV
120 130 140 150 160 170
426 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:14:44 2016 done: Fri Nov 4 09:14:45 2016
Total Scan time: 9.560 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]