Result of FASTA (omim) for
pF1KB7691
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7691, 349 aa
1>>>pF1KB7691 349 - 349 aa - 349 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8904+/-0.000428; mu= 18.1270+/- 0.027
mean_var=231.0681+/-48.352, 0's: 0 Z-trim(118.8): 346 B-trim: 33 in 1/54
Lambda= 0.084373
statistics sampled from 31825 (32209) to 31825 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.378), width: 16
Scan time: 8.640
The best scores are: opt bits E(85289)
NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349) 2437 309.4 7.7e-84
XP_011541682 (OMIM: 600366) PREDICTED: insulin gen ( 285) 1889 242.5 8.4e-64
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 1872 240.6 3.9e-63
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 1712 221.4 3.5e-57
XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279) 591 84.5 3e-16
NP_001167540 (OMIM: 600298) LIM homeobox transcrip ( 382) 592 84.9 3.3e-16
NP_796372 (OMIM: 600298) LIM homeobox transcriptio ( 382) 592 84.9 3.3e-16
NP_001167617 (OMIM: 161200,602575) LIM homeobox tr ( 406) 585 84.0 6.1e-16
NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395) 562 81.2 4.2e-15
NP_001167618 (OMIM: 161200,602575) LIM homeobox tr ( 402) 562 81.2 4.2e-15
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 483 71.5 3e-12
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 475 70.6 6.3e-12
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 475 70.6 6.4e-12
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 475 70.6 6.4e-12
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 475 70.7 6.5e-12
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 443 66.6 8.5e-11
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 443 66.8 9.7e-11
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 431 65.3 2.6e-10
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 431 65.3 2.6e-10
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 428 64.9 3.4e-10
NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346) 425 64.5 4.1e-10
NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356) 425 64.5 4.1e-10
XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 425 64.5 4.2e-10
XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 425 64.5 4.2e-10
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 424 64.4 4.6e-10
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 424 64.4 4.7e-10
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 420 64.0 6.7e-10
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363) 415 63.3 9.7e-10
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366) 415 63.3 9.7e-10
NP_954629 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 377) 415 63.3 9.9e-10
XP_011516824 (OMIM: 608215) PREDICTED: LIM/homeobo ( 378) 415 63.3 9.9e-10
NP_055183 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 392) 415 63.3 1e-09
XP_011516823 (OMIM: 608215) PREDICTED: LIM/homeobo ( 407) 415 63.4 1e-09
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 407 62.4 2e-09
XP_011507840 (OMIM: 600298) PREDICTED: LIM homeobo ( 302) 403 61.7 2.4e-09
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230) 399 61.0 3e-09
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 376 58.0 1.8e-08
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 376 58.0 1.8e-08
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 358 55.7 7.5e-08
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 358 55.7 7.5e-08
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 358 55.7 7.8e-08
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 358 55.7 7.8e-08
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 357 55.5 8.2e-08
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 357 55.5 8.2e-08
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 357 55.5 8.2e-08
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 357 55.5 8.2e-08
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 357 55.5 8.2e-08
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 357 55.5 8.2e-08
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 357 55.5 8.2e-08
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 357 55.5 8.2e-08
>>NP_002193 (OMIM: 600366) insulin gene enhancer protein (349 aa)
initn: 2437 init1: 2437 opt: 2437 Z-score: 1626.2 bits: 309.4 E(85289): 7.7e-84
Smith-Waterman score: 2437; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 IMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQ
250 260 270 280 290 300
310 320 330 340
pF1KB7 SDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
310 320 330 340
>>XP_011541682 (OMIM: 600366) PREDICTED: insulin gene en (285 aa)
initn: 1889 init1: 1889 opt: 1889 Z-score: 1266.5 bits: 242.5 E(85289): 8.4e-64
Smith-Waterman score: 1889; 100.0% identity (100.0% similar) in 276 aa overlap (74-349:10-285)
50 60 70 80 90 100
pF1KB7 KCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIE
::::::::::::::::::::::::::::::
XP_011 MEPIKIVPWLYGIKCAKCSIGFSKNDFVMRARSKVYHIE
10 20 30
110 120 130 140 150 160
pF1KB7 CFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPI
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 SARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 VIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 VQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMV
220 230 240 250 260 270
pF1KB7 ASPIEA
::::::
XP_011 ASPIEA
280
>>NP_665804 (OMIM: 609481) insulin gene enhancer protein (359 aa)
initn: 1920 init1: 1813 opt: 1872 Z-score: 1254.4 bits: 240.6 E(85289): 3.9e-63
Smith-Waterman score: 1872; 75.6% identity (91.4% similar) in 349 aa overlap (1-348:11-358)
10 20 30 40 50
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQ
.: ::: ::: ..:::::.:::::.::::::::::::::::::::.:
NP_665 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 YLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVAC
::::.::::::::::::::::.::.:::::::..:::..:.:::::..::::::::: .:
NP_665 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC
70 80 90 100 110 120
120 130 140 150 160
pF1KB7 SRQLIPGDEFALREDGLFCRADHDVV-ERASLGAGDPLSPLHPARPLQMAAEPISARQPA
::::.:::::.::: :.::::: .. :::. :. .:: :: :.. . :.::::
NP_665 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLP-DAGSGRQPA
130 140 150 160 170
170 180 190 200 210 220
pF1KB7 LRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWF
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 LRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 QNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQP
:::::::::.::.:::::::: .:::..::.::::.::.:: ::....:.. ::::.:::
NP_665 QNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 PWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
:::.::.::::::.:::::::::.:::.: .::.::.:.:.:::::::::::: ::.:
NP_665 PWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET
300 310 320 330 340 350
>>XP_016877994 (OMIM: 609481) PREDICTED: insulin gene en (534 aa)
initn: 1662 init1: 1662 opt: 1712 Z-score: 1147.6 bits: 221.4 E(85289): 3.5e-57
Smith-Waterman score: 1712; 75.5% identity (90.6% similar) in 319 aa overlap (1-318:11-328)
10 20 30 40 50
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQ
.: ::: ::: ..:::::.:::::.::::::::::::::::::::.:
XP_016 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 YLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVAC
::::.::::::::::::::::.::.:::::::..:::..:.:::::..::::::::: .:
XP_016 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC
70 80 90 100 110 120
120 130 140 150 160
pF1KB7 SRQLIPGDEFALREDGLFCRADHDVV-ERASLGAGDPLSPLHPARPLQMAAEPISARQPA
::::.:::::.::: :.::::: .. :::. :. .:: :: :.. . :.::::
XP_016 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLP-DAGSGRQPA
130 140 150 160 170
170 180 190 200 210 220
pF1KB7 LRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWF
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 QNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQP
:::::::::.::.:::::::: .:::..::.::::.::.:: ::....:.. ::::.:::
XP_016 QNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 PWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
:::.::.::::::.:::::::: .: ::
XP_016 PWKALSEFALQSDLDQPAFQQLGLLSAGGRSPRDTFRLGARGPGAPARVPLHLPLPGVSA
300 310 320 330 340 350
>>XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobox tr (279 aa)
initn: 522 init1: 317 opt: 591 Z-score: 412.6 bits: 84.5 E(85289): 3e-16
Smith-Waterman score: 591; 38.2% identity (65.7% similar) in 251 aa overlap (15-261:33-271)
10 20 30 40
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLK
:.: :: : :...::.. : :: :..
XP_011 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 CAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
:: :.. :. ::: :: : ::: :: .:...::. : ... :.:::::...:::. :
XP_011 CASCKEPLE--TTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC
70 80 90 100 110
110 120 130 140 150 160
pF1KB7 FRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSP----LHPARPLQMAA
: : .: ::: ::::.:.: :.:..:.. :: :. .: . . : .:
XP_011 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEK-ERELLSLVSPAASDSGKSDDEESLCKSA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 EPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGL
. ... : . . ::.:. : ::.:. .: ..... . .. .: ..: :. :::
XP_011 HG-AGKGTAEEGKDHKRPK---RPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 SPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQAN
: ::..:::::.: : :: . . :::: .:. : : ..
XP_011 SVRVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSDWCSHTC
240 250 260 270
290 300 310 320 330 340
pF1KB7 PVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPN
>>NP_001167540 (OMIM: 600298) LIM homeobox transcription (382 aa)
initn: 468 init1: 317 opt: 592 Z-score: 412.1 bits: 84.9 E(85289): 3.3e-16
Smith-Waterman score: 595; 35.0% identity (62.7% similar) in 300 aa overlap (15-310:33-314)
10 20 30 40
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLK
:.: :: : :...::.. : :: :..
NP_001 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 CAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
:: :.. :. ::: :: : ::: :: .:...::. : ... :.:::::...:::. :
NP_001 CASCKEPLE--TTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC
70 80 90 100 110
110 120 130 140 150 160
pF1KB7 FRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSP----LHPARPLQMAA
: : .: ::: ::::.:.: :.:..:.. :: :. .: . . : .:
NP_001 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEK-ERELLSLVSPAASDSGKSDDEESLCKSA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 EPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGL
. ... : . . ::.:. : ::.:. .: ..... . .. .: ..: :. :::
NP_001 HG-AGKGTAEEGKDHKRPK---RPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 SPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQAN
: ::..:::::.: : :: . . :::: .:. : : .... ... .: . :
NP_001 SVRVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIM--N
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 PVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPN
: . : ..:. :: .. :.:
NP_001 PY--TALPTPQQLLA--IEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTS
290 300 310 320 330 340
>>NP_796372 (OMIM: 600298) LIM homeobox transcription fa (382 aa)
initn: 468 init1: 317 opt: 592 Z-score: 412.1 bits: 84.9 E(85289): 3.3e-16
Smith-Waterman score: 595; 35.0% identity (62.7% similar) in 300 aa overlap (15-310:33-314)
10 20 30 40
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLK
:.: :: : :...::.. : :: :..
NP_796 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 CAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
:: :.. :. ::: :: : ::: :: .:...::. : ... :.:::::...:::. :
NP_796 CASCKEPLE--TTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC
70 80 90 100 110
110 120 130 140 150 160
pF1KB7 FRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSP----LHPARPLQMAA
: : .: ::: ::::.:.: :.:..:.. :: :. .: . . : .:
NP_796 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEK-ERELLSLVSPAASDSGKSDDEESLCKSA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 EPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGL
. ... : . . ::.:. : ::.:. .: ..... . .. .: ..: :. :::
NP_796 HG-AGKGTAEEGKDHKRPK---RPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 SPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQAN
: ::..:::::.: : :: . . :::: .:. : : .... ... .: . :
NP_796 SVRVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIM--N
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 PVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPN
: . : ..:. :: .. :.:
NP_796 PY--TALPTPQQLLA--IEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTS
290 300 310 320 330 340
>>NP_001167617 (OMIM: 161200,602575) LIM homeobox transc (406 aa)
initn: 466 init1: 288 opt: 585 Z-score: 407.2 bits: 84.0 E(85289): 6.1e-16
Smith-Waterman score: 585; 32.5% identity (58.5% similar) in 323 aa overlap (15-333:54-368)
10 20 30 40
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLK
..: :: : :....::. . :: ::.
NP_001 MLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNES-SWHEECLQ
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB7 CAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
:: :.: : :: . :: : :::.:: .:.. ::. : .. ..::::: :::. :
NP_001 CAACQQALTTSC--YFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGC
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB7 FRCVACSRQLIPGDEFALREDGLFCRADH----DVVERASLGAGDPLSPLHPARPLQMAA
: : .: ::: ::::.:.: :.:..:. :.. .: .: .. .. :
NP_001 FCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAK
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB7 EPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGL
: : :.:.. : ::.:. .: ..... . .. .: ..: :. :::
NP_001 GQGS--QSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGL
210 220 230 240 250
230 240 250 260 270 280
pF1KB7 SPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQAN
: ::..:::::.: : :: . .: ::.: :.. :: : : . . : .. ...
NP_001 SVRVVQVWFQNQRAKMKKLARRHQQ-QQEQQNSQRLGQGEPG-PGQGLGQEVLSSRMEGM
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB7 PVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPN
. :: . . . . .. ::: .. . ::..: .. : .:
NP_001 MASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQM-PGNDSIFHDIDSDTSLTSLSDC
320 330 340 350 360 370
pF1KB7 SMVASPIEA
NP_001 FLGSSDVGSLQARVGNPIDRLYSMQSSYFAS
380 390 400
>>NP_002307 (OMIM: 161200,602575) LIM homeobox transcrip (395 aa)
initn: 466 init1: 288 opt: 562 Z-score: 392.2 bits: 81.2 E(85289): 4.2e-15
Smith-Waterman score: 600; 32.3% identity (59.4% similar) in 347 aa overlap (15-345:54-391)
10 20 30 40
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLK
..: :: : :....::. . :: ::.
NP_002 MLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVN-ESSWHEECLQ
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB7 CAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
:: :.: : : :. :: : :::.:: .:.. ::. : .. ..::::: :::. :
NP_002 CAACQQALTTS--CYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGC
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB7 FRCVACSRQLIPGDEFALREDGLFCRADH----DVVERASLGAGDPLSPLHPARPLQMAA
: : .: ::: ::::.:.: :.:..:. :.. .: .: .. .. :
NP_002 FCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAK
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB7 EPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGL
: : :.:.. : ::.:. .: ..... . .. .: ..: :. :::
NP_002 GQGS--QSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGL
210 220 230 240 250
230 240 250 260 270
pF1KB7 SPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDK-------TNIQGMTGTPMVAASPERH
: ::..:::::.: : :: . .: :.:: ... . ..:: .. : :...
NP_002 SVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQ
260 270 280 290 300 310
280 290 300 310 320
pF1KB7 DGGLQANPVEV-----QSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEV
... .: :. :: .: .. :::. . .:...:. ::...::
NP_002 IVAMEQSPYGSSDPFQQGLTPPQMPGND-SIFHDIDSDT--SLTSLSDCFLGSSDVGSLQ
320 330 340 350 360 370
330 340
pF1KB7 ASMSSQLPDTPNSMVASPIEA
: ... . : :: .:
NP_002 ARVGNPI-DRLYSMQSSYFAS
380 390
>>NP_001167618 (OMIM: 161200,602575) LIM homeobox transc (402 aa)
initn: 466 init1: 288 opt: 562 Z-score: 392.1 bits: 81.2 E(85289): 4.2e-15
Smith-Waterman score: 585; 31.7% identity (58.9% similar) in 353 aa overlap (15-345:54-398)
10 20 30 40
pF1KB7 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLK
..: :: : :....::. . :: ::.
NP_001 MLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVN-ESSWHEECLQ
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB7 CAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC
:: :.: : : :. :: : :::.:: .:.. ::. : .. ..::::: :::. :
NP_001 CAACQQALTTS--CYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGC
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB7 FRCVACSRQLIPGDEFALREDGLFCRADH----DVVERASLGAGDPLSPLHPARPLQMAA
: : .: ::: ::::.:.: :.:..:. :.. .: .: .. .. :
NP_001 FCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAK
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB7 EPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGL
: : :.:.. : ::.:. .: ..... . .. .: ..: :. :::
NP_001 GQGS--QSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGL
210 220 230 240 250
230 240 250 260 270
pF1KB7 SPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDK-------TNIQGMTGTPMVAASPERH
: ::..:::::.: : :: . .: :.:: ... . ..:: .. : :...
NP_001 SVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQ
260 270 280 290 300 310
280 290 300 310 320
pF1KB7 DGGLQANPVEV-----QSYQPPWKV---LSDFALQS---DIDQPAFQQLVNFSEGGPGSN
... .: :. :: .. .. .: :::. . .:...:. ::.
NP_001 IVAMEQSPYGSSDPFQQGLTPPQMPGDHMNPYGNDSIFHDIDSDT--SLTSLSDCFLGSS
320 330 340 350 360 370
330 340
pF1KB7 STGSEVASMSSQLPDTPNSMVASPIEA
..:: : ... . : :: .:
NP_001 DVGSLQARVGNPI-DRLYSMQSSYFAS
380 390 400
349 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:09:03 2016 done: Sat Nov 5 04:09:05 2016
Total Scan time: 8.640 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]