Result of FASTA (omim) for
pF1KB7662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7662, 396 aa
1>>>pF1KB7662 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3951+/-0.00033; mu= 17.0320+/- 0.021
mean_var=76.6179+/-15.447, 0's: 0 Z-trim(116.0): 16 B-trim: 24 in 1/49
Lambda= 0.146524
statistics sampled from 26758 (26772) to 26758 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.314), width: 16
Scan time: 9.040
The best scores are: opt bits E(85289)
NP_071761 (OMIM: 607055) dimethyladenosine transfe ( 396) 2715 583.3 3.5e-166
XP_016857544 (OMIM: 607055) PREDICTED: dimethylade ( 203) 1395 304.0 2.1e-82
XP_011542550 (OMIM: 607055) PREDICTED: dimethylade ( 295) 1110 243.9 3.8e-64
XP_011534172 (OMIM: 607033) PREDICTED: dimethylade ( 267) 159 42.8 0.0012
XP_011534173 (OMIM: 607033) PREDICTED: dimethylade ( 267) 159 42.8 0.0012
XP_011534174 (OMIM: 607033) PREDICTED: dimethylade ( 267) 159 42.8 0.0012
NP_057104 (OMIM: 607033) dimethyladenosine transfe ( 346) 159 42.9 0.0014
>>NP_071761 (OMIM: 607055) dimethyladenosine transferase (396 aa)
initn: 2715 init1: 2715 opt: 2715 Z-score: 3104.4 bits: 583.3 E(85289): 3.5e-166
Smith-Waterman score: 2715; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB7 MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 PGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 MIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDE
310 320 330 340 350 360
370 380 390
pF1KB7 KVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
::::::::::::::::::::::::::::::::::::
NP_071 KVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
370 380 390
>>XP_016857544 (OMIM: 607055) PREDICTED: dimethyladenosi (203 aa)
initn: 1395 init1: 1395 opt: 1395 Z-score: 1600.5 bits: 304.0 E(85289): 2.1e-82
Smith-Waterman score: 1395; 100.0% identity (100.0% similar) in 203 aa overlap (194-396:1-203)
170 180 190 200 210 220
pF1KB7 PPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRI
::::::::::::::::::::::::::::::
XP_016 MFPSRGEKRALWKLAYDLYSCTSIYKFGRI
10 20 30
230 240 250 260 270 280
pF1KB7 EVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENP
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB7 KRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLT
100 110 120 130 140 150
350 360 370 380 390
pF1KB7 PLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
160 170 180 190 200
>>XP_011542550 (OMIM: 607055) PREDICTED: dimethyladenosi (295 aa)
initn: 1110 init1: 1110 opt: 1110 Z-score: 1272.6 bits: 243.9 E(85289): 3.8e-64
Smith-Waterman score: 1811; 74.5% identity (74.5% similar) in 396 aa overlap (1-396:1-295)
10 20 30 40 50 60
pF1KB7 MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEA
::::::::::::::
XP_011 VALESDKTFIPHLE----------------------------------------------
130
190 200 210 220 230 240
pF1KB7 VPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMAD
:::::
XP_011 -------------------------------------------------------KLMAD
250 260 270 280 290 300
pF1KB7 PGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQ
140 150 160 170 180 190
310 320 330 340 350 360
pF1KB7 MIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDE
200 210 220 230 240 250
370 380 390
pF1KB7 KVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
::::::::::::::::::::::::::::::::::::
XP_011 KVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR
260 270 280 290
>>XP_011534172 (OMIM: 607033) PREDICTED: dimethyladenosi (267 aa)
initn: 123 init1: 100 opt: 159 Z-score: 186.8 bits: 42.8 E(85289): 0.0012
Smith-Waterman score: 201; 24.3% identity (54.8% similar) in 230 aa overlap (47-271:8-217)
20 30 40 50 60 70
pF1KB7 LAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPR--KASKASLDFKRY
:. .: : : .:. . . . :. . .
XP_011 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNF
10 20 30
80 90 100 110 120 130
pF1KB7 VTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAG-AKVVALESDKTFIPHL
. : ::.. ... :. . . : .:::: .:...:.: :.....:.: ::: :
XP_011 LLDLRLTDKIVR-KAGNLTNA--YVYEVGPGPGGITRSILNADVAELLVVEKDTRFIPGL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 ESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIP-LKVV
. :. ::::..: : . . : :..: . :: : : ....
XP_011 QMLSDAAPGKLRIVHGDVLTF--------KVEKAFSESLKR-------PWEDDPPNVHII
100 110 120 130
200 210 220 230 240 250
pF1KB7 GMFPSRGEKRALWKLAYDLYSCTS-IYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLS
: .: . : .. :: . . .:: .... . .. ..: :. :. . ::
XP_011 GNLPFSVSTPLIIKWLENI-SCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQ-RSRLS
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB7 VIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKN
:. : :... . : ..:
XP_011 VMAQYLCNVRHIFTIPGQAFVPKPEIFLHLNCLHPLSGAPLWGRGDSVDPILQPPLQFCP
200 210 220 230 240 250
>>XP_011534173 (OMIM: 607033) PREDICTED: dimethyladenosi (267 aa)
initn: 123 init1: 100 opt: 159 Z-score: 186.8 bits: 42.8 E(85289): 0.0012
Smith-Waterman score: 201; 24.3% identity (54.8% similar) in 230 aa overlap (47-271:8-217)
20 30 40 50 60 70
pF1KB7 LAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPR--KASKASLDFKRY
:. .: : : .:. . . . :. . .
XP_011 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNF
10 20 30
80 90 100 110 120 130
pF1KB7 VTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAG-AKVVALESDKTFIPHL
. : ::.. ... :. . . : .:::: .:...:.: :.....:.: ::: :
XP_011 LLDLRLTDKIVR-KAGNLTNA--YVYEVGPGPGGITRSILNADVAELLVVEKDTRFIPGL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 ESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIP-LKVV
. :. ::::..: : . . : :..: . :: : : ....
XP_011 QMLSDAAPGKLRIVHGDVLTF--------KVEKAFSESLKR-------PWEDDPPNVHII
100 110 120 130
200 210 220 230 240 250
pF1KB7 GMFPSRGEKRALWKLAYDLYSCTS-IYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLS
: .: . : .. :: . . .:: .... . .. ..: :. :. . ::
XP_011 GNLPFSVSTPLIIKWLENI-SCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQ-RSRLS
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB7 VIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKN
:. : :... . : ..:
XP_011 VMAQYLCNVRHIFTIPGQAFVPKPEIFLHLNCLHPLSGAPLWGRGDSVDPILQPPLQFCP
200 210 220 230 240 250
>>XP_011534174 (OMIM: 607033) PREDICTED: dimethyladenosi (267 aa)
initn: 123 init1: 100 opt: 159 Z-score: 186.8 bits: 42.8 E(85289): 0.0012
Smith-Waterman score: 201; 24.3% identity (54.8% similar) in 230 aa overlap (47-271:8-217)
20 30 40 50 60 70
pF1KB7 LAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPR--KASKASLDFKRY
:. .: : : .:. . . . :. . .
XP_011 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNF
10 20 30
80 90 100 110 120 130
pF1KB7 VTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAG-AKVVALESDKTFIPHL
. : ::.. ... :. . . : .:::: .:...:.: :.....:.: ::: :
XP_011 LLDLRLTDKIVR-KAGNLTNA--YVYEVGPGPGGITRSILNADVAELLVVEKDTRFIPGL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 ESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIP-LKVV
. :. ::::..: : . . : :..: . :: : : ....
XP_011 QMLSDAAPGKLRIVHGDVLTF--------KVEKAFSESLKR-------PWEDDPPNVHII
100 110 120 130
200 210 220 230 240 250
pF1KB7 GMFPSRGEKRALWKLAYDLYSCTS-IYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLS
: .: . : .. :: . . .:: .... . .. ..: :. :. . ::
XP_011 GNLPFSVSTPLIIKWLENI-SCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQ-RSRLS
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB7 VIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKN
:. : :... . : ..:
XP_011 VMAQYLCNVRHIFTIPGQAFVPKPEIFLHLNCLHPLSGAPLWGRGDSVDPILQPPLQFCP
200 210 220 230 240 250
>>NP_057104 (OMIM: 607033) dimethyladenosine transferase (346 aa)
initn: 123 init1: 100 opt: 159 Z-score: 185.2 bits: 42.9 E(85289): 0.0014
Smith-Waterman score: 205; 24.1% identity (53.6% similar) in 274 aa overlap (47-308:8-253)
20 30 40 50 60 70
pF1KB7 LAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPR--KASKASLDFKRY
:. .: : : .:. . . . :. . .
NP_057 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNF
10 20 30
80 90 100 110 120 130
pF1KB7 VTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAG-AKVVALESDKTFIPHL
. : ::.. ... :. . . : .:::: .:...:.: :.....:.: ::: :
NP_057 LLDLRLTDKIVR-KAGNLTNA--YVYEVGPGPGGITRSILNADVAELLVVEKDTRFIPGL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 ESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIP-LKVV
. :. ::::..: : . . : :..: . :: : : ....
NP_057 QMLSDAAPGKLRIVHGDVLTF--------KVEKAFSESLKR-------PWEDDPPNVHII
100 110 120 130
200 210 220 230 240 250
pF1KB7 GMFPSRGEKRALWKLAYDLYSCTS-IYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLS
: .: . : .. :: . . .:: .... . .. ..: :. :. . ::
NP_057 GNLPFSVSTPLIIKWLENI-SCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQ-RSRLS
140 150 160 170 180 190
260 270 280 290 300
pF1KB7 VIWQLACEIKVLHMEPWSSF------DI-YTRKGPLENPKRRELLDQLQQKLYLIQMIPR
:. : :... . : ..: :. .. :: .:: ..: . :.. .
NP_057 VMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPK-------IEQPFKLVEKVV-
200 210 220 230 240
310 320 330 340 350 360
pF1KB7 QNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVN
::.:
NP_057 QNVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRK
250 260 270 280 290 300
396 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:04:10 2016 done: Sat Nov 5 10:04:12 2016
Total Scan time: 9.040 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]