FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7631, 320 aa
  1>>>pF1KB7631 320 - 320 aa - 320 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7112+/-0.000308; mu= 7.0129+/- 0.019
 mean_var=186.6881+/-37.149, 0's: 0 Z-trim(123.3): 34  B-trim: 2155 in 1/61
 Lambda= 0.093868
 statistics sampled from 42733 (42779) to 42733 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.502), width:  16
 Scan time:  9.820

The best scores are:                                      opt bits E(85289)
NP_002469 (OMIM: 159970) myoblast determination pr ( 320) 2225 312.8   6e-85
NP_005584 (OMIM: 159990) myogenic factor 5 [Homo s ( 255)  564 87.8 2.6e-17
NP_002470 (OMIM: 159980) myogenin [Homo sapiens]   ( 224)  422 68.5 1.5e-11
NP_002460 (OMIM: 159991,614408) myogenic factor 6  ( 242)  420 68.3 1.9e-11


>>NP_002469 (OMIM: 159970) myoblast determination protei  (320 aa)
 initn: 2225 init1: 2225 opt: 2225  Z-score: 1646.1  bits: 312.8 E(85289): 6e-85
Smith-Waterman score: 2225; 100.0% identity (100.0% similar) in 320 aa overlap (1-320:1-320)

               10        20        30        40        50        60
pF1KB7 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQS
              250       260       270       280       290       300

              310       320
pF1KB7 PDAAPQCPAGANPNPIYQVL
       ::::::::::::::::::::
NP_002 PDAAPQCPAGANPNPIYQVL
              310       320

>>NP_005584 (OMIM: 159990) myogenic factor 5 [Homo sapie  (255 aa)
 initn: 758 init1: 550 opt: 564  Z-score: 431.8  bits: 87.8 E(85289): 2.6e-17
Smith-Waterman score: 767; 48.7% identity (69.2% similar) in 279 aa overlap (17-294:5-247)

               10        20        30        40        50        60
pF1KB7 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE
                       ::  :.:. .. :::  :. ::. .: ... ::.   ::     
NP_005             MDVMDG--CQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGA-----
                             10        20        30        40      

               70        80        90       100       110       120
pF1KB7 EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR
        :.   : ..   :. ::::::::.::::::.::.:::::::::.:. ::::::::::::
NP_005 -HK---AELQ---GSDEDEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERR
                     50        60        70        80        90    

              130       140       150       160       170       180
pF1KB7 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA
       ::.:::.:::::::::..::::::::::::::::::::.:: :::.:       .  .:.
NP_005 RLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQ-------VENYYS
          100       110       120       130       140              

              190       200       210       220       230       240
pF1KB7 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP
            ::..       :. .:: ::::::: . ..:   .:. . ... :  .. .    
NP_005 L----PGQSC------SEPTSPTSNCSDGMPECNSP-VWSRKSSTFDSIYCPDVSNVYAT
           150             160       170        180       190      

              250        260       270       280       290         
pF1KB7 GKSAAVSSLDCLSSIVERI-STESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQ
        :.. .:::::::.::.:: :.:.:. :   : :. : ::    ..   . : ::     
NP_005 DKNS-LSSLDCLSNIVDRITSSEQPGLP---LQDLASLSPVASTDSQPATPGASSSRLIY
        200        210       220          230       240       250  

     300       310       320
pF1KB7 SPDAAPQCPAGANPNPIYQVL
                            
NP_005 HVL                  
                            

>>NP_002470 (OMIM: 159980) myogenin [Homo sapiens]        (224 aa)
 initn: 444 init1: 382 opt: 422  Z-score: 328.6  bits: 68.5 E(85289): 1.5e-11
Smith-Waterman score: 434; 41.7% identity (64.3% similar) in 199 aa overlap (23-217:4-183)

               10        20        30        40        50        60
pF1KB7 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE
                             . :.  ::..:       ::..  .   .:. .. .: 
NP_002                    MELYETSPYFYQEP-------RFYDGENYLPVHLQGF-EPP
                                  10               20        30    

               70         80        90       100       110         
pF1KB7 EHSHFPAAVHP-APGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRER
        . .   .. : :::  ::. . .:  .:  :.:: ::::.::::....:::.:::.::.
NP_002 GYERTELTLSPEAPGPLEDKGLGTP--EHCPGQCLPWACKVCKRKSVSVDRRRAATLREK
            40        50          60        70        80        90 

     120       130       140       150       160       170         
pF1KB7 RRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFY
       :::.:::::::.::: :  :::::::::::::.::.::: ::::: . .          :
NP_002 RRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLR---Y
             100       110       120       130       140           

     180       190       200          210       220       230      
pF1KB7 APGPLPPGRGGEHYSGDSDASSPRSNCSD---GMMDYSGPPSGARRRNCYEGAYYNEAPS
         :      :: . .  :. ::  ..::    . ...:. :                   
NP_002 RGG------GGPQPGVPSECSSHSASCSPEWGSALEFSANPGDHLLTADPTDAHNLHSLT
      150             160       170       180       190       200  

        240       250       260       270       280       290      
pF1KB7 EPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGD
                                                                   
NP_002 SIVDSITVEDVSVAFPDETMPN                                      
            210       220                                          

>>NP_002460 (OMIM: 159991,614408) myogenic factor 6 [Hom  (242 aa)
 initn: 472 init1: 388 opt: 420  Z-score: 326.7  bits: 68.3 E(85289): 1.9e-11
Smith-Waterman score: 446; 44.9% identity (58.4% similar) in 214 aa overlap (57-267:41-234)

         30        40        50        60        70        80      
pF1KB7 DDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPEEHSHFPAAVHPAPGAREDEHVRAPSG
                                     :.: . .  : :   . :   .::: :: :
NP_002 YFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSG---EEHVLAPPG
               20        30        40        50           60       

            90       100       110       120       130       140   
pF1KB7 ---HHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQR
           :  :.::.::::.::::.. .:::::::.::::::.:.:::::.::: : .:::::
NP_002 LQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQR
        70        80        90       100       110       120       

           150       160       170       180       190       200   
pF1KB7 LPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDASSPR
       ::::::::.:: ::: :: ::.  :        .   :    : .  :.  :   :.  :
NP_002 LPKVEILRSAISYIERLQDLLHRLDQQEKMQELGV-DPFSYRPKQ--ENLEG---ADFLR
       130       140       150       160        170            180 

           210       220       230       240       250       260   
pF1KB7 SNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRPGKSAAVSSLDCLSSIVERISTES
       . ::.   . :    :        ::  .          :.: ::: ::::::. ::.: 
NP_002 T-CSSQWPSVSDHSRGLVITAKEGGASID----------SSASSSLRCLSSIVDSISSEE
              190       200                 210       220       230

           270       280       290       300       310       320
pF1KB7 PAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQSPDAAPQCPAGANPNPIYQVL
          :                                                     
NP_002 RKLPCVEEVVEK                                             
              240                                               




320 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:04:19 2016 done: Fri Nov  4 09:04:20 2016
 Total Scan time:  9.820 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]