Result of FASTA (omim) for
pF1KB7623
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7623, 314 aa
1>>>pF1KB7623 314 - 314 aa - 314 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7475+/-0.000302; mu= 8.6566+/- 0.019
mean_var=223.3231+/-45.121, 0's: 0 Z-trim(124.3): 259 B-trim: 137 in 2/58
Lambda= 0.085824
statistics sampled from 45428 (45726) to 45428 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.823), E-opt: 0.2 (0.536), width: 16
Scan time: 7.440
The best scores are: opt bits E(85289)
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 2174 280.9 2.3e-75
NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324) 1220 162.8 8.5e-40
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 1214 162.1 1.4e-39
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 1214 162.1 1.4e-39
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 1214 162.1 1.4e-39
NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271) 1202 160.5 3.5e-39
XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271) 1202 160.5 3.5e-39
NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271) 1202 160.5 3.5e-39
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 801 110.9 3.4e-24
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 359 56.2 1.1e-07
NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 344 54.3 3.8e-07
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 340 53.7 4.3e-07
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 343 54.3 4.8e-07
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 343 54.4 5.4e-07
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 343 54.4 5.4e-07
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 343 54.4 5.4e-07
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 343 54.4 5.6e-07
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 340 53.9 5.6e-07
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 331 52.7 1.1e-06
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 331 52.7 1.1e-06
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289) 331 52.7 1.1e-06
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 332 53.0 1.2e-06
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 332 53.0 1.2e-06
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 328 52.6 2e-06
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 328 52.6 2e-06
NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 328 52.6 2.1e-06
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297) 321 51.5 2.6e-06
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297) 321 51.5 2.6e-06
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 321 51.6 3.4e-06
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 51.6 3.4e-06
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 51.6 3.4e-06
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 51.6 3.4e-06
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 321 51.6 3.4e-06
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 51.6 3.4e-06
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 321 51.6 3.4e-06
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 320 51.6 4.3e-06
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 312 50.3 5e-06
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 313 50.5 5.6e-06
NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299) 307 49.7 8.6e-06
NP_001290437 (OMIM: 612019) intestine-specific hom ( 245) 302 49.0 1.2e-05
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 301 48.9 1.3e-05
NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 300 48.9 1.8e-05
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 300 48.9 1.8e-05
NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245) 297 48.4 1.8e-05
NP_005306 (OMIM: 601845) homeobox protein goosecoi ( 205) 295 48.1 1.9e-05
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 295 48.1 2e-05
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 291 47.5 2.5e-05
XP_006711451 (OMIM: 167420,202650) PREDICTED: pair ( 198) 290 47.4 2.8e-05
NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 291 47.7 3.4e-05
NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 287 47.0 3.5e-05
>>NP_002644 (OMIM: 119800,186550,602149) pituitary homeo (314 aa)
initn: 2174 init1: 2174 opt: 2174 Z-score: 1474.0 bits: 280.9 E(85289): 2.3e-75
Smith-Waterman score: 2174; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KB7 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGL
250 260 270 280 290 300
310
pF1KB7 QGPASGLNACQYNS
::::::::::::::
NP_002 QGPASGLNACQYNS
310
>>NP_000316 (OMIM: 137600,180500,180550,601542,604229) p (324 aa)
initn: 1148 init1: 595 opt: 1220 Z-score: 835.5 bits: 162.8 E(85289): 8.5e-40
Smith-Waterman score: 1228; 62.1% identity (78.2% similar) in 330 aa overlap (1-312:1-318)
10 20 30 40
pF1KB7 MDAFKGGMSLERLPEGLRPPPPP------PHDMGPAFHLARPADPR------EPLE-NSA
:. .:: . ::. : . :. .. : :: :..:: . :: ..
NP_000 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLA-PGQPRSLDSSKHRLEVHTI
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 SESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEAT
:..:. : ::... . :. :: ::.::.:::.:::::::::::::::::::
NP_000 SDTSSPEAAEKDKSQQGKN-EDV--------GAEDPSKKKRQRRQRTHFTSQQLQELEAT
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 FQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGL
:::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::
NP_000 FQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 VQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTM
.:::.:.: ::::::::::.:. : :::::: :::::. ::::::::: :.:::::.:
NP_000 MQPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSM
180 190 200 210 220
230 240 250 260 270 280
pF1KB7 PSSMGPGAVPGMPNSGLN---NINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSL
::: :.:: :.:.:.:: :.:::.. :::::. ::::. :. :: ::::::::::
NP_000 SSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSL
230 240 250 260 270 280
290 300 310
pF1KB7 ASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
::::::.::::::::...:.:::.:.::::
NP_000 ASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
290 300 310 320
>>NP_001191327 (OMIM: 137600,180500,180550,601542,604229 (317 aa)
initn: 1148 init1: 595 opt: 1214 Z-score: 831.6 bits: 162.1 E(85289): 1.4e-39
Smith-Waterman score: 1214; 69.0% identity (84.7% similar) in 274 aa overlap (44-312:42-311)
20 30 40 50 60 70
pF1KB7 PEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAG
:. .:. .:... :.. : . : :
NP_001 CVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEK--DKSQQG
20 30 40 50 60
80 90 100 110 120 130
pF1KB7 GTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRV
. ::.::.:::.::::::::::::::::::::::::::::: :::::::::::: ::
NP_001 KNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARV
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 RVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAP
::::::::::::::::::: .:::.:. :::.::.:::.:.: ::::::::::.:. :
NP_001 RVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYP-GYSYNNWAAKGLTSAS
130 140 150 160 170 180
200 210 220 230 240
pF1KB7 LSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLN---NINNL
:::::: :::::. ::::::::: :.:::::.: ::: :.:: :.:.:.:: :.:::
NP_001 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLN
.. :::::. ::::. :. :: ::::::::::::::::.::::::::...:.:::.:.
NP_001 SSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLS
250 260 270 280 290 300
310
pF1KB7 ACQYNS
::::
NP_001 ACQYAVDRPV
310
>>NP_001191326 (OMIM: 137600,180500,180550,601542,604229 (317 aa)
initn: 1148 init1: 595 opt: 1214 Z-score: 831.6 bits: 162.1 E(85289): 1.4e-39
Smith-Waterman score: 1214; 69.0% identity (84.7% similar) in 274 aa overlap (44-312:42-311)
20 30 40 50 60 70
pF1KB7 PEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAG
:. .:. .:... :.. : . : :
NP_001 CVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEK--DKSQQG
20 30 40 50 60
80 90 100 110 120 130
pF1KB7 GTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRV
. ::.::.:::.::::::::::::::::::::::::::::: :::::::::::: ::
NP_001 KNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARV
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 RVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAP
::::::::::::::::::: .:::.:. :::.::.:::.:.: ::::::::::.:. :
NP_001 RVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYP-GYSYNNWAAKGLTSAS
130 140 150 160 170 180
200 210 220 230 240
pF1KB7 LSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLN---NINNL
:::::: :::::. ::::::::: :.:::::.: ::: :.:: :.:.:.:: :.:::
NP_001 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLN
.. :::::. ::::. :. :: ::::::::::::::::.::::::::...:.:::.:.
NP_001 SSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLS
250 260 270 280 290 300
310
pF1KB7 ACQYNS
::::
NP_001 ACQYAVDRPV
310
>>NP_700475 (OMIM: 137600,180500,180550,601542,604229) p (317 aa)
initn: 1148 init1: 595 opt: 1214 Z-score: 831.6 bits: 162.1 E(85289): 1.4e-39
Smith-Waterman score: 1214; 69.0% identity (84.7% similar) in 274 aa overlap (44-312:42-311)
20 30 40 50 60 70
pF1KB7 PEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAG
:. .:. .:... :.. : . : :
NP_700 CVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEK--DKSQQG
20 30 40 50 60
80 90 100 110 120 130
pF1KB7 GTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRV
. ::.::.:::.::::::::::::::::::::::::::::: :::::::::::: ::
NP_700 KNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARV
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 RVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAP
::::::::::::::::::: .:::.:. :::.::.:::.:.: ::::::::::.:. :
NP_700 RVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYP-GYSYNNWAAKGLTSAS
130 140 150 160 170 180
200 210 220 230 240
pF1KB7 LSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLN---NINNL
:::::: :::::. ::::::::: :.:::::.: ::: :.:: :.:.:.:: :.:::
NP_700 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLN
.. :::::. ::::. :. :: ::::::::::::::::.::::::::...:.:::.:.
NP_700 SSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLS
250 260 270 280 290 300
310
pF1KB7 ACQYNS
::::
NP_700 ACQYAVDRPV
310
>>NP_700476 (OMIM: 137600,180500,180550,601542,604229) p (271 aa)
initn: 1148 init1: 595 opt: 1202 Z-score: 824.4 bits: 160.5 E(85289): 3.5e-39
Smith-Waterman score: 1202; 76.2% identity (89.5% similar) in 239 aa overlap (79-312:29-265)
50 60 70 80 90 100
pF1KB7 ESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATF
::.::.:::.::::::::::::::::::::
NP_700 METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATF
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 QRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLV
::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::.
NP_700 QRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLM
60 70 80 90 100 110
170 180 190 200 210 220
pF1KB7 QPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMP
:::.:.: ::::::::::.:. : :::::: :::::. ::::::::: :.:::::.:
NP_700 QPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMS
120 130 140 150 160 170
230 240 250 260 270 280
pF1KB7 SSMGPGAVPGMPNSGLN---NINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLA
::: :.:: :.:.:.:: :.:::.. :::::. ::::. :. :: :::::::::::
NP_700 SSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLA
180 190 200 210 220 230
290 300 310
pF1KB7 SLRLKSKQHSSFGYGGLQGPASGLNACQYNS
:::::.::::::::...:.:::.:.::::
NP_700 SLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
240 250 260 270
>>XP_011530329 (OMIM: 137600,180500,180550,601542,604229 (271 aa)
initn: 1148 init1: 595 opt: 1202 Z-score: 824.4 bits: 160.5 E(85289): 3.5e-39
Smith-Waterman score: 1202; 76.2% identity (89.5% similar) in 239 aa overlap (79-312:29-265)
50 60 70 80 90 100
pF1KB7 ESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATF
::.::.:::.::::::::::::::::::::
XP_011 METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATF
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 QRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLV
::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::.
XP_011 QRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLM
60 70 80 90 100 110
170 180 190 200 210 220
pF1KB7 QPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMP
:::.:.: ::::::::::.:. : :::::: :::::. ::::::::: :.:::::.:
XP_011 QPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMS
120 130 140 150 160 170
230 240 250 260 270 280
pF1KB7 SSMGPGAVPGMPNSGLN---NINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLA
::: :.:: :.:.:.:: :.:::.. :::::. ::::. :. :: :::::::::::
XP_011 SSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLA
180 190 200 210 220 230
290 300 310
pF1KB7 SLRLKSKQHSSFGYGGLQGPASGLNACQYNS
:::::.::::::::...:.:::.:.::::
XP_011 SLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
240 250 260 270
>>NP_001191328 (OMIM: 137600,180500,180550,601542,604229 (271 aa)
initn: 1148 init1: 595 opt: 1202 Z-score: 824.4 bits: 160.5 E(85289): 3.5e-39
Smith-Waterman score: 1202; 76.2% identity (89.5% similar) in 239 aa overlap (79-312:29-265)
50 60 70 80 90 100
pF1KB7 ESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATF
::.::.:::.::::::::::::::::::::
NP_001 METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATF
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 QRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLV
::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::.
NP_001 QRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLM
60 70 80 90 100 110
170 180 190 200 210 220
pF1KB7 QPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMP
:::.:.: ::::::::::.:. : :::::: :::::. ::::::::: :.:::::.:
NP_001 QPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMS
120 130 140 150 160 170
230 240 250 260 270 280
pF1KB7 SSMGPGAVPGMPNSGLN---NINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLA
::: :.:: :.:.:.:: :.:::.. :::::. ::::. :. :: :::::::::::
NP_001 SSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLA
180 190 200 210 220 230
290 300 310
pF1KB7 SLRLKSKQHSSFGYGGLQGPASGLNACQYNS
:::::.::::::::...:.:::.:.::::
NP_001 SLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
240 250 260 270
>>NP_005020 (OMIM: 107250,602669,610623) pituitary homeo (302 aa)
initn: 841 init1: 558 opt: 801 Z-score: 555.5 bits: 110.9 E(85289): 3.4e-24
Smith-Waterman score: 969; 56.3% identity (75.3% similar) in 300 aa overlap (31-312:3-296)
10 20 30 40 50
pF1KB7 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREP-LENSASESSDTELPEKE
: : :. : : : : . . .:::.
NP_005 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHG
10 20 30
60 70 80 90 100 110
pF1KB7 -RGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSM
.: : . : ..:. : :. .: . ::::::::::::::::::::::::::::::::
NP_005 CKGQEHSDSEKASASLPG-GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMST
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 REEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAG
:::::::::::: ::::::::::::::::::.:: .::::... ..::: :::.:: :
NP_005 REEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYP-G
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 YSYNNWAAKSLAPAPLSTKSFTF-FNSMS--PLSSQSMFSAPSSISSMTMPSSMG-PGAV
:::.:: :.::: ::..:.: : :::.. ::.:: .:: ::::.. .::. . ::.:
NP_005 YSYGNWPPKALAP-PLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTV
160 170 180 190 200
240 250 260 270 280
pF1KB7 PGMPNSGLNNINNLTGSSLNSAMSPGA--CPYGTPA--------SPYSVYRDTCNSSLAS
:: :.. :..... . .:.: :: :::.. : ::: :::: :::::::
NP_005 PG-PGA-LQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPY-VYRDPCNSSLAS
210 220 230 240 250 260
290 300 310
pF1KB7 LRLKSKQHSSFGYGGLQGP--ASGLNACQYNS
::::.:::.::.: ...:: :..:. :::
NP_005 LRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
270 280 290 300
>>NP_115485 (OMIM: 604529) homeobox protein orthopedia [ (325 aa)
initn: 320 init1: 285 opt: 359 Z-score: 259.3 bits: 56.2 E(85289): 1.1e-07
Smith-Waterman score: 385; 32.6% identity (56.1% similar) in 310 aa overlap (12-293:30-319)
10 20 30 40
pF1KB7 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPAD--PR
:: : : : :..: .. : :
NP_115 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ
: . . .: .. . :. .: ::. :: . . : . ..::.:.::.:: :
NP_115 EDITTVGSTPASLAVSAKDPDKQP-GPQ----GGPNPSQAGQQQGQQKQKRHRTRFTPAQ
70 80 90 100 110
110 120 130 140 150 160
pF1KB7 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGY
:.::: .: ...:::. ::::.:. .::: ::.:::.::::::.::... .. :
NP_115 LNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTL
120 130 140 150 160 170
170 180 190 200
pF1KB7 VPQFSGLVQ-PYEDVYAAG--------YSYNN--WAAKSL---APAPLSTKSFTFFNSMS
.: :: : : . ::. . :. ::: .. . :: .. ..:.
NP_115 LPT-PGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPP-ALGRQQAMA
180 190 200 210 220 230
210 220 230 240 250
pF1KB7 PLSSQSMFSA---PSSIS-SMTMPSSMGPG--------AVPGMPNSGLNNINNLTGSSLN
:: ..: :.:.. : .. .: : : : ::: ..: . .:..:
NP_115 QSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSG----
240 250 260 270 280
260 270 280 290 300 310
pF1KB7 SAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
:: : ..: : .:.: : :.:::: :. .:.
NP_115 ---SPQLC--SSPDSS-DVWRGT---SIASLRRKALEHTVSMSFT
290 300 310 320
314 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:00:56 2016 done: Fri Nov 4 09:00:57 2016
Total Scan time: 7.440 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]