Result of FASTA (ccds) for
pF1KB7623
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7623, 314 aa
1>>>pF1KB7623 314 - 314 aa - 314 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0294+/-0.000743; mu= 6.7155+/- 0.046
mean_var=205.6504+/-42.428, 0's: 0 Z-trim(116.7): 183 B-trim: 0 in 0/53
Lambda= 0.089435
statistics sampled from 17113 (17307) to 17113 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.532), width: 16
Scan time: 2.600
The best scores are: opt bits E(32554)
CCDS4182.1 PITX1 gene_id:5307|Hs108|chr5 ( 314) 2174 292.0 4e-79
CCDS3694.1 PITX2 gene_id:5308|Hs108|chr4 ( 324) 1220 168.9 4.6e-42
CCDS3692.1 PITX2 gene_id:5308|Hs108|chr4 ( 317) 1214 168.2 7.8e-42
CCDS3693.1 PITX2 gene_id:5308|Hs108|chr4 ( 271) 1202 166.5 2e-41
CCDS7532.1 PITX3 gene_id:5309|Hs108|chr10 ( 302) 801 114.8 8.3e-26
>>CCDS4182.1 PITX1 gene_id:5307|Hs108|chr5 (314 aa)
initn: 2174 init1: 2174 opt: 2174 Z-score: 1534.0 bits: 292.0 E(32554): 4e-79
Smith-Waterman score: 2174; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KB7 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 YNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGL
250 260 270 280 290 300
310
pF1KB7 QGPASGLNACQYNS
::::::::::::::
CCDS41 QGPASGLNACQYNS
310
>>CCDS3694.1 PITX2 gene_id:5308|Hs108|chr4 (324 aa)
initn: 1148 init1: 595 opt: 1220 Z-score: 868.6 bits: 168.9 E(32554): 4.6e-42
Smith-Waterman score: 1228; 62.1% identity (78.2% similar) in 330 aa overlap (1-312:1-318)
10 20 30 40
pF1KB7 MDAFKGGMSLERLPEGLRPPPPP------PHDMGPAFHLARPADPR------EPLE-NSA
:. .:: . ::. : . :. .. : :: :..:: . :: ..
CCDS36 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLA-PGQPRSLDSSKHRLEVHTI
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 SESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEAT
:..:. : ::... . :. :: ::.::.:::.:::::::::::::::::::
CCDS36 SDTSSPEAAEKDKSQQGKN-EDV--------GAEDPSKKKRQRRQRTHFTSQQLQELEAT
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 FQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGL
:::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::
CCDS36 FQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 VQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTM
.:::.:.: ::::::::::.:. : :::::: :::::. ::::::::: :.:::::.:
CCDS36 MQPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSM
180 190 200 210 220
230 240 250 260 270 280
pF1KB7 PSSMGPGAVPGMPNSGLN---NINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSL
::: :.:: :.:.:.:: :.:::.. :::::. ::::. :. :: ::::::::::
CCDS36 SSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSL
230 240 250 260 270 280
290 300 310
pF1KB7 ASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
::::::.::::::::...:.:::.:.::::
CCDS36 ASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
290 300 310 320
>>CCDS3692.1 PITX2 gene_id:5308|Hs108|chr4 (317 aa)
initn: 1148 init1: 595 opt: 1214 Z-score: 864.6 bits: 168.2 E(32554): 7.8e-42
Smith-Waterman score: 1214; 69.0% identity (84.7% similar) in 274 aa overlap (44-312:42-311)
20 30 40 50 60 70
pF1KB7 PEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAG
:. .:. .:... :.. : . : :
CCDS36 CVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEK--DKSQQG
20 30 40 50 60
80 90 100 110 120 130
pF1KB7 GTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRV
. ::.::.:::.::::::::::::::::::::::::::::: :::::::::::: ::
CCDS36 KNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARV
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 RVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAP
::::::::::::::::::: .:::.:. :::.::.:::.:.: ::::::::::.:. :
CCDS36 RVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYP-GYSYNNWAAKGLTSAS
130 140 150 160 170 180
200 210 220 230 240
pF1KB7 LSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLN---NINNL
:::::: :::::. ::::::::: :.:::::.: ::: :.:: :.:.:.:: :.:::
CCDS36 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLN
.. :::::. ::::. :. :: ::::::::::::::::.::::::::...:.:::.:.
CCDS36 SSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLS
250 260 270 280 290 300
310
pF1KB7 ACQYNS
::::
CCDS36 ACQYAVDRPV
310
>>CCDS3693.1 PITX2 gene_id:5308|Hs108|chr4 (271 aa)
initn: 1148 init1: 595 opt: 1202 Z-score: 857.1 bits: 166.5 E(32554): 2e-41
Smith-Waterman score: 1202; 76.2% identity (89.5% similar) in 239 aa overlap (79-312:29-265)
50 60 70 80 90 100
pF1KB7 ESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATF
::.::.:::.::::::::::::::::::::
CCDS36 METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATF
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 QRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLV
::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::.
CCDS36 QRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLM
60 70 80 90 100 110
170 180 190 200 210 220
pF1KB7 QPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTMP
:::.:.: ::::::::::.:. : :::::: :::::. ::::::::: :.:::::.:
CCDS36 QPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMS
120 130 140 150 160 170
230 240 250 260 270 280
pF1KB7 SSMGPGAVPGMPNSGLN---NINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLA
::: :.:: :.:.:.:: :.:::.. :::::. ::::. :. :: :::::::::::
CCDS36 SSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSLA
180 190 200 210 220 230
290 300 310
pF1KB7 SLRLKSKQHSSFGYGGLQGPASGLNACQYNS
:::::.::::::::...:.:::.:.::::
CCDS36 SLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
240 250 260 270
>>CCDS7532.1 PITX3 gene_id:5309|Hs108|chr10 (302 aa)
initn: 841 init1: 558 opt: 801 Z-score: 576.8 bits: 114.8 E(32554): 8.3e-26
Smith-Waterman score: 969; 56.3% identity (75.3% similar) in 300 aa overlap (31-312:3-296)
10 20 30 40 50
pF1KB7 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREP-LENSASESSDTELPEKE
: : :. : : : : . . .:::.
CCDS75 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHG
10 20 30
60 70 80 90 100 110
pF1KB7 -RGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSM
.: : . : ..:. : :. .: . ::::::::::::::::::::::::::::::::
CCDS75 CKGQEHSDSEKASASLPG-GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMST
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 REEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAG
:::::::::::: ::::::::::::::::::.:: .::::... ..::: :::.:: :
CCDS75 REEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYP-G
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 YSYNNWAAKSLAPAPLSTKSFTF-FNSMS--PLSSQSMFSAPSSISSMTMPSSMG-PGAV
:::.:: :.::: ::..:.: : :::.. ::.:: .:: ::::.. .::. . ::.:
CCDS75 YSYGNWPPKALAP-PLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTV
160 170 180 190 200
240 250 260 270 280
pF1KB7 PGMPNSGLNNINNLTGSSLNSAMSPGA--CPYGTPA--------SPYSVYRDTCNSSLAS
:: :.. :..... . .:.: :: :::.. : ::: :::: :::::::
CCDS75 PG-PGA-LQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPY-VYRDPCNSSLAS
210 220 230 240 250 260
290 300 310
pF1KB7 LRLKSKQHSSFGYGGLQGP--ASGLNACQYNS
::::.:::.::.: ...:: :..:. :::
CCDS75 LRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
270 280 290 300
314 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:00:55 2016 done: Fri Nov 4 09:00:55 2016
Total Scan time: 2.600 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]