Result of FASTA (omim) for
pF1KB7614
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7614, 360 aa
1>>>pF1KB7614 360 - 360 aa - 360 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9031+/-0.000327; mu= 14.4378+/- 0.021
mean_var=261.3764+/-53.017, 0's: 0 Z-trim(124.4): 55 B-trim: 837 in 2/58
Lambda= 0.079331
statistics sampled from 45956 (46028) to 45956 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.836), E-opt: 0.2 (0.54), width: 16
Scan time: 9.560
The best scores are: opt bits E(85289)
NP_002692 (OMIM: 164177) POU domain, class 5, tran ( 360) 2531 302.1 1.3e-81
NP_001153014 (OMIM: 615739) putative POU domain, c ( 359) 2412 288.5 1.6e-77
NP_001272916 (OMIM: 164177) POU domain, class 5, t ( 265) 1515 185.6 1.1e-46
NP_001167002 (OMIM: 164177) POU domain, class 5, t ( 190) 1299 160.7 2.5e-39
NP_976034 (OMIM: 164177) POU domain, class 5, tran ( 190) 1299 160.7 2.5e-39
NP_001272915 (OMIM: 164177) POU domain, class 5, t ( 164) 1134 141.7 1.1e-33
NP_006227 (OMIM: 602480) POU domain, class 3, tran ( 500) 667 89.0 2.6e-17
NP_002690 (OMIM: 602479) POU domain, class 3, tran ( 451) 651 87.1 8.6e-17
NP_000298 (OMIM: 300039,304400) POU domain, class ( 361) 638 85.4 2.1e-16
NP_005595 (OMIM: 600494) POU domain, class 3, tran ( 443) 635 85.2 3e-16
XP_011507957 (OMIM: 164175) PREDICTED: POU domain, ( 671) 570 78.0 6.6e-14
NP_001185715 (OMIM: 164175) POU domain, class 2, t ( 703) 570 78.1 6.8e-14
XP_011507956 (OMIM: 164175) PREDICTED: POU domain, ( 743) 570 78.1 7e-14
NP_001185712 (OMIM: 164175) POU domain, class 2, t ( 755) 570 78.1 7e-14
NP_002688 (OMIM: 164175) POU domain, class 2, tran ( 766) 570 78.1 7.1e-14
XP_011507955 (OMIM: 164175) PREDICTED: POU domain, ( 769) 570 78.1 7.1e-14
XP_011541043 (OMIM: 607394) PREDICTED: POU domain, ( 403) 554 75.9 1.8e-13
XP_011541045 (OMIM: 607394) PREDICTED: POU domain, ( 403) 554 75.9 1.8e-13
XP_011541044 (OMIM: 607394) PREDICTED: POU domain, ( 403) 554 75.9 1.8e-13
XP_011541041 (OMIM: 607394) PREDICTED: POU domain, ( 432) 554 75.9 1.8e-13
XP_011541042 (OMIM: 607394) PREDICTED: POU domain, ( 432) 554 75.9 1.8e-13
NP_055167 (OMIM: 607394) POU domain, class 2, tran ( 436) 554 75.9 1.9e-13
NP_001231611 (OMIM: 607394) POU domain, class 2, t ( 438) 554 75.9 1.9e-13
XP_016872976 (OMIM: 607394) PREDICTED: POU domain, ( 356) 546 74.9 3.1e-13
NP_006228 (OMIM: 601632) POU domain, class 4, tran ( 419) 514 71.3 4.3e-12
NP_000297 (OMIM: 173110,613038) pituitary-specific ( 291) 480 67.2 5.3e-11
NP_001116229 (OMIM: 173110,613038) pituitary-speci ( 317) 480 67.3 5.5e-11
NP_002691 (OMIM: 602459,602460) POU domain, class ( 338) 444 63.2 9.9e-10
NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 444 63.3 1.1e-09
XP_016882385 (OMIM: 164176) PREDICTED: POU domain, ( 600) 410 59.7 2e-08
XP_016882381 (OMIM: 164176) PREDICTED: POU domain, ( 701) 410 59.8 2.2e-08
XP_016882378 (OMIM: 164176) PREDICTED: POU domain, ( 711) 410 59.8 2.2e-08
XP_016882375 (OMIM: 164176) PREDICTED: POU domain, ( 711) 410 59.8 2.2e-08
XP_016882379 (OMIM: 164176) PREDICTED: POU domain, ( 711) 410 59.8 2.2e-08
XP_016882376 (OMIM: 164176) PREDICTED: POU domain, ( 711) 410 59.8 2.2e-08
XP_016882377 (OMIM: 164176) PREDICTED: POU domain, ( 711) 410 59.8 2.2e-08
XP_016882373 (OMIM: 164176) PREDICTED: POU domain, ( 723) 410 59.8 2.2e-08
XP_016882374 (OMIM: 164176) PREDICTED: POU domain, ( 723) 410 59.8 2.2e-08
XP_011525345 (OMIM: 164176) PREDICTED: POU domain, ( 537) 401 58.6 3.9e-08
NP_001159490 (OMIM: 601583,609062) POU domain, cla ( 655) 399 58.5 5.1e-08
NP_001193955 (OMIM: 164176) POU domain, class 2, t ( 467) 392 57.4 7.3e-08
NP_001193954 (OMIM: 164176) POU domain, class 2, t ( 479) 392 57.5 7.4e-08
XP_011525343 (OMIM: 164176) PREDICTED: POU domain, ( 501) 392 57.5 7.6e-08
XP_016882384 (OMIM: 164176) PREDICTED: POU domain, ( 602) 392 57.6 8.4e-08
XP_016882383 (OMIM: 164176) PREDICTED: POU domain, ( 602) 392 57.6 8.4e-08
XP_011525342 (OMIM: 164176) PREDICTED: POU domain, ( 624) 392 57.6 8.6e-08
XP_016856997 (OMIM: 164175) PREDICTED: POU domain, ( 381) 349 52.4 2e-06
NP_002689 (OMIM: 164176) POU domain, class 2, tran ( 463) 350 52.6 2e-06
XP_011525344 (OMIM: 164176) PREDICTED: POU domain, ( 485) 350 52.7 2.1e-06
XP_005259067 (OMIM: 164176) PREDICTED: POU domain, ( 586) 350 52.8 2.3e-06
>>NP_002692 (OMIM: 164177) POU domain, class 5, transcri (360 aa)
initn: 2531 init1: 2531 opt: 2531 Z-score: 1586.3 bits: 302.1 E(85289): 1.3e-81
Smith-Waterman score: 2531; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360)
10 20 30 40 50 60
pF1KB7 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
310 320 330 340 350 360
>>NP_001153014 (OMIM: 615739) putative POU domain, class (359 aa)
initn: 1734 init1: 1734 opt: 2412 Z-score: 1512.7 bits: 288.5 E(85289): 1.6e-77
Smith-Waterman score: 2412; 95.8% identity (97.5% similar) in 360 aa overlap (1-360:1-359)
10 20 30 40 50 60
pF1KB7 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI
:::::::::::::::::::::: : ::::::: :::::::::::::::::::::::::::
NP_001 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG
::::::::.:::::::::::::::::::::::::::.::::::::::.::::::::: ::
NP_001 PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS
::::::::::::::.:::::::::::::::::::::::::::::::::: ::::::::::
NP_001 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR
: ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 VRGNLENLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
250 260 270 280 290
310 320 330 340 350 360
pF1KB7 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
::::::::::::: :::::::::::::::::::::::::::::.:::::: :::::::::
NP_001 AGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
300 310 320 330 340 350
>>NP_001272916 (OMIM: 164177) POU domain, class 5, trans (265 aa)
initn: 1515 init1: 1515 opt: 1515 Z-score: 959.1 bits: 185.6 E(85289): 1.1e-46
Smith-Waterman score: 1515; 99.6% identity (100.0% similar) in 226 aa overlap (135-360:40-265)
110 120 130 140 150 160
pF1KB7 SNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQ
.:::::::::::::::::::::::::::::
NP_001 ATRRFLNPEWKGEIDNWCVYVLTSLLPFKIQSQDIKALQKELEQFAKLLKQKRITLGYTQ
10 20 30 40 50 60
170 180 190 200 210 220
pF1KB7 ADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAE
70 80 90 100 110 120
230 240 250 260 270 280
pF1KB7 TLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQK
130 140 150 160 170 180
290 300 310 320 330 340
pF1KB7 GKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEA
190 200 210 220 230 240
350 360
pF1KB7 FPPVSVTTLGSPMHSN
::::::::::::::::
NP_001 FPPVSVTTLGSPMHSN
250 260
>>NP_001167002 (OMIM: 164177) POU domain, class 5, trans (190 aa)
initn: 1299 init1: 1299 opt: 1299 Z-score: 827.0 bits: 160.7 E(85289): 2.5e-39
Smith-Waterman score: 1299; 99.5% identity (100.0% similar) in 190 aa overlap (171-360:1-190)
150 160 170 180 190 200
pF1KB7 ALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKL
.:::::::::::::::::::::::::::::
NP_001 MGVLFGKVFSQTTICRFEALQLSFKNMCKL
10 20 30
210 220 230 240 250 260
pF1KB7 RPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQI
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB7 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHF
100 110 120 130 140 150
330 340 350 360
pF1KB7 GTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
::::::::::::::::::::::::::::::::::::::::
NP_001 GTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
160 170 180 190
>>NP_976034 (OMIM: 164177) POU domain, class 5, transcri (190 aa)
initn: 1299 init1: 1299 opt: 1299 Z-score: 827.0 bits: 160.7 E(85289): 2.5e-39
Smith-Waterman score: 1299; 99.5% identity (100.0% similar) in 190 aa overlap (171-360:1-190)
150 160 170 180 190 200
pF1KB7 ALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKL
.:::::::::::::::::::::::::::::
NP_976 MGVLFGKVFSQTTICRFEALQLSFKNMCKL
10 20 30
210 220 230 240 250 260
pF1KB7 RPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 RPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQI
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB7 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHF
100 110 120 130 140 150
330 340 350 360
pF1KB7 GTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
::::::::::::::::::::::::::::::::::::::::
NP_976 GTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
160 170 180 190
>>NP_001272915 (OMIM: 164177) POU domain, class 5, trans (164 aa)
initn: 1134 init1: 1134 opt: 1134 Z-score: 725.5 bits: 141.7 E(85289): 1.1e-33
Smith-Waterman score: 1134; 100.0% identity (100.0% similar) in 164 aa overlap (197-360:1-164)
170 180 190 200 210 220
pF1KB7 VGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETL
::::::::::::::::::::::::::::::
NP_001 MCKLRPLLQKWVEEADNNENLQEICKAETL
10 20 30
230 240 250 260 270 280
pF1KB7 VQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGK
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB7 RSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFP
100 110 120 130 140 150
350 360
pF1KB7 PVSVTTLGSPMHSN
::::::::::::::
NP_001 PVSVTTLGSPMHSN
160
>>NP_006227 (OMIM: 602480) POU domain, class 3, transcri (500 aa)
initn: 744 init1: 619 opt: 667 Z-score: 431.9 bits: 89.0 E(85289): 2.6e-17
Smith-Waterman score: 667; 45.2% identity (63.8% similar) in 290 aa overlap (39-321:213-494)
10 20 30 40 50 60
pF1KB7 FAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYE
: :: . : : : :. ::
NP_006 HPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPG-GFTVNGMLSAPPGPG
190 200 210 220 230 240
70 80 90 100 110 120
pF1KB7 FCGGMAYCGPQVGVGLVPQGGLETSQPE-GEAGVGVESNSDGASPEPCTVT-P----GAV
:: : : : .:: : .. . :: .: . .. :.: . : :.
NP_006 GGGGGAGGGAQ---SLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGG
250 260 270 280 290
130 140 150 160 170 180
pF1KB7 KLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQT
:... .:.. . .:::::: .::.:: ::.:::::::.::.:.:.:::::
NP_006 GGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQT
300 310 320 330 340 350
190 200 210 220 230 240
pF1KB7 TICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRV
::::::::::::::::::.:::.::.::::.. . . . .:.:::: ::::: :
NP_006 TICRFEALQLSFKNMCKLKPLLNKWLEEADSSTG-SPTSIDKIAAQGRKRKKRTSIEVSV
360 370 380 390 400 410
250 260 270 280 290 300
pF1KB7 RGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA
.: ::. ::.::::. :.:...:..: :::.:::::::::::: :: . :.. . .
NP_006 KGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDV
420 430 440 450 460 470
310 320 330 340 350 360
pF1KB7 GSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
: : :: : :: :
NP_006 YSQV--GTVSADTPP-PHHGLQTSVQ
480 490 500
>>NP_002690 (OMIM: 602479) POU domain, class 3, transcri (451 aa)
initn: 677 init1: 603 opt: 651 Z-score: 422.5 bits: 87.1 E(85289): 8.6e-17
Smith-Waterman score: 691; 43.3% identity (62.6% similar) in 321 aa overlap (9-318:159-432)
10 20 30
pF1KB7 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSF
.: . ::::: : .: :.
NP_002 AQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAG----------MLAA
130 140 150 160 170
40 50 60 70 80 90
pF1KB7 QGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGE
: .:::. .. .. . : :::. : :. : . :::... . .
NP_002 GGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAH-------GHAHAGGLHAAAAHLH
180 190 200 210 220 230
100 110 120 130 140 150
pF1KB7 AGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRI
:.: ..: : . :. : :.: .:::::: .::.::
NP_002 PGAGGGGSSVGEHSD----------------EDAP--SSD------DLEQFAKQFKQRRI
240 250 260
160 170 180 190 200 210
pF1KB7 TLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNE---
::.:::::::.::.:.:.:::::::::::::::::::::::.:::.::.::.:..
NP_002 KLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSP
270 280 290 300 310 320
220 230 240 250 260 270
pF1KB7 -NLQEICKAETLVQARKRK-RTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDV
::..: .:.:::: ::::: :.: ::. ::.::::. ..:. .:..: :::.:
NP_002 TNLDKIA-----AQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEV
330 340 350 360 370 380
280 290 300 310 320
pF1KB7 VRVWFCNRRQKGKR----SSSDYAQREDFEAAG--SPFSGGPVSFPLAPGPHFGTPGYGS
::::::::::: :: ... . .: : : .: .:: .: : :: :
NP_002 VRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGP-GGGGASPPSAPPPPPPAALHHH
390 400 410 420 430 440
330 340 350 360
pF1KB7 PHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
NP_002 HHHTLPGSVQ
450
>>NP_000298 (OMIM: 300039,304400) POU domain, class 3, t (361 aa)
initn: 619 init1: 619 opt: 638 Z-score: 415.4 bits: 85.4 E(85289): 2.1e-16
Smith-Waterman score: 665; 49.8% identity (69.5% similar) in 243 aa overlap (58-295:114-343)
30 40 50 60 70 80
pF1KB7 GWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGM---AYCGPQVGV-G
:: : : : .:. .: : : :
NP_000 GREDLQLGAIIHHRSPHVAHHSPHTNHPNAWGASPAPNPSITSSGQPLNVYSQPGFTVSG
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB7 LVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQ
.. .::: : : :.....: : :. . . .. :..: ..:
NP_000 MLEHGGL-TPPP---AAASAQSLHPVLREPPDHGELGSHHCQDHSDEETP--TSD-----
150 160 170 180 190
150 160 170 180 190 200
pF1KB7 KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPL
::::::: .::.:: ::.:::::::.::.:.:.:::::::::::::::::::::::.::
NP_000 -ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPL
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB7 LQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVRGNLENLFLQCPKPTLQQISH
:.::.::::.. . . . .:.:::: ::::: :.: ::. ::.::::. :.::
NP_000 LNKWLEEADSSTG-SPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISS
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB7 IAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGT
.:..: :::.:::::::::::: :: . :.
NP_000 LADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEVYSHTVKTDTSCHDL
320 330 340 350 360
330 340 350 360
pF1KB7 PGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
>>NP_005595 (OMIM: 600494) POU domain, class 3, transcri (443 aa)
initn: 739 init1: 617 opt: 635 Z-score: 412.6 bits: 85.2 E(85289): 3e-16
Smith-Waterman score: 654; 46.7% identity (65.9% similar) in 255 aa overlap (49-287:163-411)
20 30 40 50 60 70
pF1KB7 GDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPY-EFCGGMAYCG
:: : . . :: . ::. :
NP_005 QQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLYSQ
140 150 160 170 180 190
80 90 100 110 120
pF1KB7 PQVGV-GLVPQGGLETSQPEGEAGVGVESNSD-----GASPEPCT--------VTPGAVK
:. : :.. :: :: : :... : :.: . :
NP_005 PSFTVNGMLGAGG----QPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGP
200 210 220 230 240
130 140 150 160 170 180
pF1KB7 LEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTT
. ...:. ..: . . .:::::: .::.:: ::.:::::::.::.:.:.::::::
NP_005 PGHPGAHHDPHSDEDTPT-SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTT
250 260 270 280 290 300
190 200 210 220 230 240
pF1KB7 ICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVR
:::::::::::::::::.:::.::.::::.. . . . .:.:::: ::::: :.
NP_005 ICRFEALQLSFKNMCKLKPLLNKWLEEADSSSG-SPTSIDKIAAQGRKRKKRTSIEVSVK
310 320 330 340 350 360
250 260 270 280 290 300
pF1KB7 GNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAG
: ::. ::.::::. :.:. .:..: :::.:::::::::::: ::
NP_005 GALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVY
370 380 390 400 410 420
310 320 330 340 350 360
pF1KB7 SPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
NP_005 GGSRDTPPHHGVQTPVQ
430 440
360 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 09:06:26 2016 done: Sat Nov 5 09:06:28 2016
Total Scan time: 9.560 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]