Result of FASTA (omim) for
pF1KB7603
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7603, 297 aa
1>>>pF1KB7603 297 - 297 aa - 297 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8002+/-0.00037; mu= 1.2289+/- 0.023
mean_var=240.2728+/-48.788, 0's: 0 Z-trim(121.3): 210 B-trim: 19 in 1/52
Lambda= 0.082741
statistics sampled from 37390 (37659) to 37390 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.442), width: 16
Scan time: 8.590
The best scores are: opt bits E(85289)
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297) 2013 252.6 6.8e-67
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297) 2013 252.6 6.8e-67
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289) 1916 241.0 2e-63
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 1916 241.0 2e-63
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 1916 241.0 2e-63
NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 758 102.9 9.7e-22
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 758 102.9 9.7e-22
NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299) 564 79.6 8e-15
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 355 54.7 2.5e-07
NP_001297089 (OMIM: 106210,120430,136520,148190,16 ( 286) 327 51.3 2.6e-06
NP_001297090 (OMIM: 106210,120430,136520,148190,16 ( 286) 327 51.3 2.6e-06
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 327 51.5 3.4e-06
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 327 51.5 3.4e-06
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 327 51.5 3.4e-06
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 327 51.5 3.4e-06
NP_001245392 (OMIM: 106210,120430,136520,148190,16 ( 436) 327 51.5 3.5e-06
NP_001595 (OMIM: 106210,120430,136520,148190,16555 ( 436) 327 51.5 3.5e-06
NP_001297087 (OMIM: 106210,120430,136520,148190,16 ( 436) 327 51.5 3.5e-06
NP_001245391 (OMIM: 106210,120430,136520,148190,16 ( 436) 327 51.5 3.5e-06
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 324 51.0 3.5e-06
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 321 50.7 4.5e-06
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 318 50.3 5.6e-06
NP_001012677 (OMIM: 611164) arginine-fifty homeobo ( 315) 316 50.1 6.8e-06
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 308 49.0 1.2e-05
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 300 48.0 1.8e-05
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 300 48.1 2.2e-05
XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271) 300 48.1 2.3e-05
NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271) 300 48.1 2.3e-05
NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271) 300 48.1 2.3e-05
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 301 48.3 2.5e-05
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 300 48.1 2.6e-05
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 300 48.1 2.6e-05
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 300 48.1 2.6e-05
NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324) 300 48.2 2.6e-05
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 299 48.1 3.3e-05
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 299 48.1 3.4e-05
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 298 48.0 3.4e-05
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 298 48.0 3.4e-05
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 298 48.0 3.4e-05
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 298 48.0 3.5e-05
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 297 48.0 4.5e-05
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 297 48.0 4.5e-05
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 297 48.0 4.5e-05
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 297 48.0 4.6e-05
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 292 47.2 5.1e-05
NP_006874 (OMIM: 312865,400020) short stature home ( 225) 288 46.6 5.4e-05
NP_001290437 (OMIM: 612019) intestine-specific hom ( 245) 288 46.6 5.8e-05
XP_006713791 (OMIM: 602504) PREDICTED: short statu ( 190) 285 46.2 6.1e-05
XP_016862544 (OMIM: 602504) PREDICTED: short statu ( 190) 285 46.2 6.1e-05
XP_016862542 (OMIM: 602504) PREDICTED: short statu ( 204) 285 46.2 6.5e-05
>>NP_068374 (OMIM: 600037,610125,613986) homeobox protei (297 aa)
initn: 2013 init1: 2013 opt: 2013 Z-score: 1321.9 bits: 252.6 E(85289): 6.8e-67
Smith-Waterman score: 2013; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
250 260 270 280 290
>>NP_001257454 (OMIM: 600037,610125,613986) homeobox pro (297 aa)
initn: 2013 init1: 2013 opt: 2013 Z-score: 1321.9 bits: 252.6 E(85289): 6.8e-67
Smith-Waterman score: 2013; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
250 260 270 280 290
>>NP_758840 (OMIM: 600037,610125,613986) homeobox protei (289 aa)
initn: 1928 init1: 1725 opt: 1916 Z-score: 1259.5 bits: 241.0 E(85289): 2e-63
Smith-Waterman score: 1916; 97.3% identity (97.3% similar) in 297 aa overlap (1-297:1-289)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
:::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_758 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP--------ATPRKQRRERTTFTRAQLDV
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
240 250 260 270 280
>>NP_001257452 (OMIM: 600037,610125,613986) homeobox pro (289 aa)
initn: 1928 init1: 1725 opt: 1916 Z-score: 1259.5 bits: 241.0 E(85289): 2e-63
Smith-Waterman score: 1916; 97.3% identity (97.3% similar) in 297 aa overlap (1-297:1-289)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
:::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_001 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP--------ATPRKQRRERTTFTRAQLDV
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
240 250 260 270 280
>>NP_001257453 (OMIM: 600037,610125,613986) homeobox pro (289 aa)
initn: 1928 init1: 1725 opt: 1916 Z-score: 1259.5 bits: 241.0 E(85289): 2e-63
Smith-Waterman score: 1916; 97.3% identity (97.3% similar) in 297 aa overlap (1-297:1-289)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
:::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_001 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP--------ATPRKQRRERTTFTRAQLDV
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
240 250 260 270 280
>>NP_001186699 (OMIM: 600036) homeobox protein OTX1 [Hom (354 aa)
initn: 845 init1: 442 opt: 758 Z-score: 511.3 bits: 102.9 E(85289): 9.7e-22
Smith-Waterman score: 987; 56.1% identity (68.5% similar) in 337 aa overlap (1-269:1-321)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
::::::::::..:::.:. .::::::::::: :::::::::::::::.::::
NP_001 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
::::::::::::::::::::::::::::::::::::::::::::: :.:. .: ::::
NP_001 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ---QSGSGTKSRPAK
60 70 80 90 100
130 140 150
pF1KB7 KKTSPAREVSSESGTSGQFTPP---SSTSVPTIASSSA--------------PV------
::.::.:: :: : .::::::: ::.: . ::::. ::
NP_001 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL
110 120 130 140 150 160
160 170 180 190
pF1KB7 ------SIWSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQA
:::::::::: : : :.: .:::::: :::.: :.
NP_001 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG
170 180 190 200 210 220
200 210 220 230 240
pF1KB7 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPAS---
..:.::: . :.:::::.::.:::.::: :. : ::::. .....: .. : .
NP_001 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHP
230 240 250 260 270 280
250 260 270 280 290
pF1KB7 LST-------------QGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSW
:: ::::.:.:.:::. ::::::.
NP_001 LSQSSGHHHHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYK
290 300 310 320 330 340
pF1KB7 KFQVL
NP_001 DQASWRFQVL
350
>>NP_055377 (OMIM: 600036) homeobox protein OTX1 [Homo s (354 aa)
initn: 845 init1: 442 opt: 758 Z-score: 511.3 bits: 102.9 E(85289): 9.7e-22
Smith-Waterman score: 987; 56.1% identity (68.5% similar) in 337 aa overlap (1-269:1-321)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
::::::::::..:::.:. .::::::::::: :::::::::::::::.::::
NP_055 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
::::::::::::::::::::::::::::::::::::::::::::: :.:. .: ::::
NP_055 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ---QSGSGTKSRPAK
60 70 80 90 100
130 140 150
pF1KB7 KKTSPAREVSSESGTSGQFTPP---SSTSVPTIASSSA--------------PV------
::.::.:: :: : .::::::: ::.: . ::::. ::
NP_055 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL
110 120 130 140 150 160
160 170 180 190
pF1KB7 ------SIWSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQA
:::::::::: : : :.: .:::::: :::.: :.
NP_055 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG
170 180 190 200 210 220
200 210 220 230 240
pF1KB7 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPAS---
..:.::: . :.:::::.::.:::.::: :. : ::::. .....: .. : .
NP_055 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHP
230 240 250 260 270 280
250 260 270 280 290
pF1KB7 LST-------------QGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSW
:: ::::.:.:.:::. ::::::.
NP_055 LSQSSGHHHHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYK
290 300 310 320 330 340
pF1KB7 KFQVL
NP_055 DQASWRFQVL
350
>>NP_000545 (OMIM: 120970,268000,602225,613829) cone-rod (299 aa)
initn: 646 init1: 410 opt: 564 Z-score: 387.1 bits: 79.6 E(85289): 8e-15
Smith-Waterman score: 899; 50.2% identity (70.7% similar) in 317 aa overlap (1-297:1-299)
10 20 30 40 50
pF1KB7 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLD
::.:.. : :.::.:.:. ..::.: .: :: ..:::::::::::::.::.
NP_000 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYP--------SAPRKQRRERTTFTRSQLE
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 VLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQN
::::::::.:::.. ::::::::::::::::::::::::::::: :::: :::
NP_000 ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 KVRPAKKKTS----PAREVSSES-GTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLS
:.::::.:.. :. .: . : : ...:: . ... : :::::::: :::
NP_000 KARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLP
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 DP-----LSTSSSCMQRSYPMTYTQASGYSQG---YAGSTSYFGGMDCGSYLTPMHHQLP
. .... : . : :::. ::.. .. :.. .:::.:.: ::.:: ::
NP_000 EAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 GPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNA-
::. :::.. .: : :::.::: :.::: : .: :..:: :..::...:
NP_000 GPA--LSPLSGPSVGPSLAQSPTSLSGQSYGAY-----SPVDSLEFKDPTGTWKFTYNPM
240 250 260 270 280
290
pF1KB7 DCLDYKDQTSSWKFQVL
: :::::: :.::::.:
NP_000 DPLDYKDQ-SAWKFQIL
290
>>NP_005160 (OMIM: 602078,602753) paired mesoderm homeob (284 aa)
initn: 330 init1: 308 opt: 355 Z-score: 252.5 bits: 54.7 E(85289): 2.5e-07
Smith-Waterman score: 358; 36.1% identity (54.5% similar) in 244 aa overlap (8-244:47-278)
10 20 30
pF1KB7 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPG-PWA
:: . : : . : : . : . :.
NP_005 EASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYK
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 SCPAAT----PRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQV
: . ::::: ::::: ::: :: .::.:.::::. :::.::::.: :.::::
NP_005 FFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQV
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 WFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFT-PPSSTSVPTIA
::.::::: :.:.. . : . ::: . :: :::. : . : :. :. ..
NP_005 WFQNRRAKFRKQERAASAKGAAGAAGAKK--GEAR-CSSEDDDSKESTCSPTPDSTASLP
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB7 SSSAPVSIWSPA-SISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCG
:: .. :: : ::: :... . :. . .: . : .:. : .
NP_005 PPPAP-GLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGP----GAGAA
200 210 220 230 240
220 230 240 250 260 270
pF1KB7 SYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQ
: . ::: :.. . : . .::
NP_005 ELLKAWQPAESGPG----PFSGVLSSFHRKPGPALKTNLF
250 260 270 280
280 290
pF1KB7 TASWKLNFNADCLDYKDQTSSWKFQVL
>>NP_001297089 (OMIM: 106210,120430,136520,148190,165550 (286 aa)
initn: 304 init1: 275 opt: 327 Z-score: 234.4 bits: 51.3 E(85289): 2.6e-06
Smith-Waterman score: 327; 33.2% identity (61.1% similar) in 211 aa overlap (44-253:72-274)
20 30 40 50 60 70
pF1KB7 GLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDI
:: .:.::.::. :...:: : .:.:::.
NP_001 QQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDV
50 60 70 80 90 100
80 90 100 110 120 130
pF1KB7 FMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSES
: ::..: ::.:::.:.::::.::::: :.... ... : . :.. : . .: .
NP_001 FARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQ
110 120 130 140 150 160
140 150 160 170 180 190
pF1KB7 GTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGY
:: :: . .. . . . . ... :. . ... :: : .:.:.:
NP_001 PIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVP---SQTSSY
170 180 190 200 210
200 210 220 230 240 250
pF1KB7 SQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPA-SLSTQGYG
: : : .: . .: :: : : . .::::...:: ::. :. .: :
NP_001 SCMLPTSPSV-NGRSYDTY-TPPHMQ---THMNSQPMGTSGTTSTGLISPGVSVPVQVPG
220 230 240 250 260 270
260 270 280 290
pF1KB7 ASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
.
NP_001 SEPDMSQYWPRLQ
280
297 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:05:29 2016 done: Sat Nov 5 08:05:30 2016
Total Scan time: 8.590 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]